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Latin American Trans-ancestry INitiative for OCD genomics (LATINO): Study protocol.
Crowley JJ, Cappi C, Ochoa-Panaifo ME, et al. Latin American Trans-ancestry INitiative for OCD genomics (LATINO): Study protocol. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2023:e32962. doi:10.1002/ajmg.b.32962DOIGoogle ScholarPubMed
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OCD candidate gene /EAAT3 impacts basal ganglia-mediated activity and stereotypic behavior.
Zike ID, Chohan MO, Kopelman JM, et al. OCD candidate gene /EAAT3 impacts basal ganglia-mediated activity and stereotypic behavior. Proc Natl Acad Sci U S A. 2017;114(22):5719-5724. doi:10.1073/pnas.1701736114DOIGoogle ScholarPubMed
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Integrating evolutionary and regulatory information with a multispecies approach implicates genes and pathways in obsessive-compulsive disorder.
Noh HJ, Tang R, Flannick J, et al. Integrating evolutionary and regulatory information with a multispecies approach implicates genes and pathways in obsessive-compulsive disorder. Nat Commun. 2017;8(1):774. doi:10.1038/s41467-017-00831-xDOIGoogle ScholarPubMed
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Striatal circuits, habits, and implications for obsessive-compulsive disorder.
Burguière E, Monteiro P, Mallet L, Feng G, Graybiel AM. Striatal circuits, habits, and implications for obsessive-compulsive disorder. Curr Opin Neurobiol. 2015;30:59-65. doi:10.1016/j.conb.2014.08.008DOIGoogle ScholarPubMed
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Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder.
Wan Y, Ade KK, Caffall Z, et al. Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder. Biol Psychiatry. 2014;75(8):623-30. doi:10.1016/j.biopsych.2013.01.008DOIGoogle ScholarPubMed
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Neurobiology of obsessive-compulsive disorder: insights into neural circuitry dysfunction through mouse genetics.
Ting JT, Feng G. Neurobiology of obsessive-compulsive disorder: insights into neural circuitry dysfunction through mouse genetics. Curr Opin Neurobiol. 2011;21(6):842-8. doi:10.1016/j.conb.2011.04.010DOIGoogle ScholarPubMed
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Genome-wide association study of Tourette's syndrome.
Scharf JM, Yu D, Mathews CA, et al. Genome-wide association study of Tourette’s syndrome. Mol Psychiatry. 2013;18(6):721-8. doi:10.1038/mp.2012.69DOIGoogle ScholarPubMed
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Learning From Animal Models of Obsessive-Compulsive Disorder.
Monteiro P, Feng G. Learning From Animal Models of Obsessive-Compulsive Disorder. Biol Psychiatry. 2016;79(1):7-16. doi:10.1016/j.biopsych.2015.04.020DOIGoogle ScholarPubMed
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Web-based phenotyping for Tourette Syndrome: Reliability of common co-morbid diagnoses.
Darrow SM, Illmann C, Gauvin C, et al. Web-based phenotyping for Tourette Syndrome: Reliability of common co-morbid diagnoses. Psychiatry Res. 2015;228(3):816-25. doi:10.1016/j.psychres.2015.05.017DOIGoogle ScholarPubMed
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Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder.
Tang R, Noh HJ, Wang D, et al. Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder. Genome Biol. 2014;15(3):R25. doi:10.1186/gb-2014-15-3-r25DOIGoogle ScholarPubMed
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In March of 2020, Broad Institute converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks.

We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap).

Broad Genomics Platform sequences a whole human genome every four minutes.

More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research.

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Through Broad's Scientists in the Classroom program, Broad researchers visit every 8th grade classroom in Cambridge each year to talk about genetics and evolution.

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In November 2022, Broad’s Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th.

By the end of 2022, Broad’s COVID-19 testing lab had processed more than 37 million tests.

Working with Addgene, Broad Institute has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries.

The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Chan School of Public Health to study the genetics of severe mental illness, has recruited more than 42,000 participants in Ethiopia, Kenya, Uganda, and South Africa.

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