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The phospholipid PI(3,4)P is an apical identity determinant.
Román-Fernández Álvaro, Roignot J, Sandilands E, et al. The phospholipid PI(3,4)P is an apical identity determinant. Nat Commun. 2018;9(1):5041. doi:10.1038/s41467-018-07464-8PubMedGoogle ScholarDOI
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Presence of thoracic and lumbar vertebral malformations in pugs with and without chronic neurological deficits.
Rohdin C, Häggström J, Ljungvall I, et al. Presence of thoracic and lumbar vertebral malformations in pugs with and without chronic neurological deficits. Vet J. 2018;241:24-30. doi:10.1016/j.tvjl.2018.09.008PubMedGoogle ScholarDOI
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Hepatotrophic properties in dogs of human FKBP, the binding protein for FK506 and rapamycin.
Starzl TE, Schreiber SL, Albers MW, Porter KA, Foglieni CS, Francavilla A. Hepatotrophic properties in dogs of human FKBP, the binding protein for FK506 and rapamycin. Transplantation. 1991;52(4):751-3.PubMedGoogle Scholar
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Effect of sodium nitrate loading on electrolyte transport by the renal tubule.
Kahn T, Bosch J, Levitt MF, Goldstein MH. Effect of sodium nitrate loading on electrolyte transport by the renal tubule. Am J Physiol. 1975;229(3):746-53.PubMedGoogle Scholar
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The discovery of a potent and selective lethal factor inhibitor for adjunct therapy of anthrax infection.
Xiong Y, Wiltsie J, Woods A, et al. The discovery of a potent and selective lethal factor inhibitor for adjunct therapy of anthrax infection. Bioorg Med Chem Lett. 2006;16(4):964-8. doi:10.1016/j.bmcl.2005.10.088PubMedGoogle ScholarDOI
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America's lost dogs.
Goodman L, Karlsson EK. America’s lost dogs. Science. 2018;361(6397):27-28. doi:10.1126/science.aau1306PubMedGoogle ScholarDOI
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An exome sequencing based approach for genome-wide association studies in the dog.
Broeckx BJG, Derrien T, Mottier S, et al. An exome sequencing based approach for genome-wide association studies in the dog. Sci Rep. 2017;7(1):15680. doi:10.1038/s41598-017-15947-9PubMedGoogle ScholarDOI
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Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Gaya M, Barral P, Burbage M, et al. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. 2018;172(3):517-533.e20. doi:10.1016/j.cell.2017.11.036PubMedGoogle ScholarDOI
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A novel, safe, fast and efficient treatment for Her2-positive and negative bladder cancer utilizing an EGF-anthrax toxin chimera.
Jack S, Madhivanan K, Ramadesikan S, et al. A novel, safe, fast and efficient treatment for Her2-positive and negative bladder cancer utilizing an EGF-anthrax toxin chimera. Int J Cancer. 2020;146(2):449-460. doi:10.1002/ijc.32719PubMedGoogle ScholarDOI
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High prevalence of gait abnormalities in pugs.
Rohdin C, Jäderlund KH, Ljungvall I, Lindblad-Toh K, Häggström J. High prevalence of gait abnormalities in pugs. Vet Rec. 2018;182(6):167. doi:10.1136/vr.104510PubMedGoogle ScholarDOI
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In March of 2020, Broad Institute converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks.

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Working with Addgene, Broad Institute has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries.

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