Fanning S, Haque A, Imberdis T, et al. Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. Mol Cell. 2019;73(5):1001-1014.e8. doi:10.1016/j.molcel.2018.11.028.
Buss CG, Dudani JS, Akana RTK, Fleming HE, Bhatia SN. Protease activity sensors noninvasively classify bacterial infections and antibiotic responses. EBioMedicine. 2018;38:248-256. doi:10.1016/j.ebiom.2018.11.031.
Mandt REK, Lafuente-Monasterio MJ, Sakata-Kato T, et al. In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model. Sci Transl Med. 2019;11(521). doi:10.1126/scitranslmed.aav1636.
Manoli I, Sysol JR, Epping MW, et al. FGF21 underlies a hormetic response to metabolic stress in methylmalonic acidemia. JCI Insight. 2018;3(23). doi:10.1172/jci.insight.124351.
Anahtar M, Chan LW, Ko H, et al. Host protease activity classifies pneumonia etiology. Proc Natl Acad Sci U S A. 2022;119(25):e2121778119. doi:10.1073/pnas.2121778119.
Bouziat R, Biering SB, Kouame E, et al. Murine Norovirus Infection Induces T1 Inflammatory Responses to Dietary Antigens. Cell Host Microbe. 2018;24(5):677-688.e5. doi:10.1016/j.chom.2018.10.004.
Gould RA, Aziz H, Woods CE, et al. ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm. Nat Genet. 2019;51(1):42-50. doi:10.1038/s41588-018-0265-y.
Fang C, Lee KK, Nietupski R, et al. Discovery of heterocyclic replacements for the coumarin core of anti-tubercular FadD32 inhibitors. Bioorg Med Chem Lett. 2018;28(22):3529-3533. doi:10.1016/j.bmcl.2018.09.037.
Vatanen T, Franzosa EA, Schwager R, et al. The human gut microbiome in early-onset type 1 diabetes from the TEDDY study. Nature. 2018;562(7728):589-594. doi:10.1038/s41586-018-0620-2.
Dawson TM, Golde TE, Lagier-Tourenne C. Animal models of neurodegenerative diseases. Nat Neurosci. 2018;21(10):1370-1379. doi:10.1038/s41593-018-0236-8.