1.
Haggarty SJ, Koeller KM, Wong JC, Butcher RA, Schreiber SL. Multidimensional chemical genetic analysis of diversity-oriented synthesis-derived deacetylase inhibitors using cell-based assays. Chem Biol. 2003;10(5):383-96.
1.
Strausberg RL, Schreiber SL. From knowing to controlling: a path from genomics to drugs using small molecule probes. Science. 2003;300(5617):294-5. doi:10.1126/science.1083395.
1.
Kubota H, Lim J, Depew KM, Schreiber SL. Pathway development and pilot library realization in diversity-oriented synthesis: exploring Ferrier and Pauson-Khand reactions on a glycal template. Chem Biol. 2002;9(2):265-76.
1.
Blackwell HE, Pérez L, Stavenger RA, et al. A one-bead, one-stock solution approach to chemical genetics: part 1. Chem Biol. 2001;8(12):1167-82.
1.
Zhong C, Wang Y, Hung AW, Schreiber SL, Young DW. Diastereoselective control of intramolecular aza-Michael reactions using achiral catalysts. Org Lett. 2011;13(20):5556-9. doi:10.1021/ol202276h.
1.
Evensen E, Joseph-McCarthy D, Weiss GA, Schreiber SL, Karplus M. Ligand design by a combinatorial approach based on modeling and experiment: application to HLA-DR4. J Comput Aided Mol Des. 2007;21(7):395-418. doi:10.1007/s10822-007-9119-x.
1.
Zhou G, Ferrer M, Chopra R, et al. The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core. Bioorg Med Chem. 2000;8(9):2219-27.
1.
Franz AK, Dreyfuss PD, Schreiber SL. Synthesis and cellular profiling of diverse organosilicon small molecules. J Am Chem Soc. 2007;129(5):1020-1. doi:10.1021/ja067552n.
1.
Ferrer M, Kapoor TM, Strassmaier T, et al. Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements. Nat Struct Biol. 1999;6(10):953-60. doi:10.1038/13324.
1.
Kumar N, Kiuchi M, Tallarico JA, Schreiber SL. Small-molecule diversity using a skeletal transformation strategy. Org Lett. 2005;7(13):2535-8. doi:10.1021/ol0504345.