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Utility of Mycobacterium tuberculosis genome sequencing snapshots to assess transmission dynamics over time.
Yuen CM, Huang CC, Millones AK, et al. Utility of Mycobacterium tuberculosis genome sequencing snapshots to assess transmission dynamics over time. The Journal of infectious diseases. 2023. doi:10.1093/infdis/jiad515PubMedDOIGoogle Scholar
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Temporal development of the gut microbiome in early childhood from the TEDDY study.
Stewart CJ, Ajami NJ, O’Brien JL, et al. Temporal development of the gut microbiome in early childhood from the TEDDY study. Nature. 2018;562(7728):583-588. doi:10.1038/s41586-018-0617-xGoogle ScholarPubMedDOI
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Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models.
Brown EA, Lautz JD, Davis TR, et al. Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models. Mol Autism. 2018;9:48. doi:10.1186/s13229-018-0229-1PubMedDOIGoogle Scholar
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Whole-genome comparison of urinary pathogenic Escherichia coli and faecal isolates of UTI patients and healthy controls.
Nielsen KL, Stegger M, Kiil K, et al. Whole-genome comparison of urinary pathogenic Escherichia coli and faecal isolates of UTI patients and healthy controls. Int J Med Microbiol. 2017;307(8):497-507. doi:10.1016/j.ijmm.2017.09.007PubMedDOIGoogle Scholar
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Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer.
Robertson G, Kim J, Al-Ahmadie H, et al. Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer. Cell. 2017;171(3):540-556.e25. doi:10.1016/j.cell.2017.09.007PubMedDOIGoogle Scholar
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Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages.
Goudot C, Coillard A, Villani AC, et al. Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages. Immunity. 2017;47(3):582-596.e6. doi:10.1016/j.immuni.2017.08.016PubMedDOIGoogle Scholar
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CLIC, a tool for expanding biological pathways based on co-expression across thousands of datasets.
Li Y, Jourdain AA, Calvo SE, Liu JS, Mootha VK. CLIC, a tool for expanding biological pathways based on co-expression across thousands of datasets. PLoS Comput Biol. 2017;13(7):e1005653. doi:10.1371/journal.pcbi.1005653PubMedDOIGoogle Scholar
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: An Intricate Dance of Anther Smut and Its Host.
San Toh S, Chen Z, Rouchka EC, Schultz DJ, Cuomo CA, Perlin MH. : An Intricate Dance of Anther Smut and Its Host. G3 (Bethesda). 2018;8(2):505-518. doi:10.1534/g3.117.300318PubMedDOIGoogle Scholar
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SynerClust: a highly scalable, synteny-aware orthologue clustering tool.
Georgescu CH, Manson AL, Griggs AD, et al. SynerClust: a highly scalable, synteny-aware orthologue clustering tool. Microb Genom. 2018;4(11). doi:10.1099/mgen.0.000231PubMedDOIGoogle Scholar
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Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis.
Udler MS, Kim J, von Grotthuss M, et al. Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis. PLoS Med. 2018;15(9):e1002654. doi:10.1371/journal.pmed.1002654PubMedDOIGoogle Scholar
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In March of 2020, Broad Institute converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks.

We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap).

Broad Genomics Platform sequences a whole human genome every four minutes.

More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research.

The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery.

In 2021, our sustainability efforts sent more than 80 percent of waste from the Genomics Platform to either a recycling facility or to an incineration plant that generates electricity.

Through Broad's Scientists in the Classroom program, Broad researchers visit every 8th grade classroom in Cambridge each year to talk about genetics and evolution.

Every summer, 18 high school students spend six weeks at Broad working side-by-side with mentors on cutting-edge research.

In November 2022, Broad’s Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th.

By the end of 2022, Broad’s COVID-19 testing lab had processed more than 37 million tests.

Working with Addgene, Broad Institute has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries.

The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Chan School of Public Health to study the genetics of severe mental illness, has recruited more than 42,000 participants in Ethiopia, Kenya, Uganda, and South Africa.

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