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The forty years of medical genetics in China.
Cai L, Zheng LA, He L. The forty years of medical genetics in China. J Genet Genomics. 2018;45(11):569-582. doi:10.1016/j.jgg.2018.10.001Google ScholarPubMedDOI
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Genetic effects influencing risk for major depressive disorder in China and Europe.
Bigdeli TB, Ripke S, Peterson RE, et al. Genetic effects influencing risk for major depressive disorder in China and Europe. Transl Psychiatry. 2017;7(3):e1074. doi:10.1038/tp.2016.292Google ScholarPubMedDOI
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Chinese scientists and US leadership in the life sciences.
Holtzman SH, Cohen R, Levin JM, Maraganore J, Signatories to the Statement. Chinese scientists and US leadership in the life sciences. Nat Biotechnol. 2019;37(11):1261-1263. doi:10.1038/s41587-019-0285-xGoogle ScholarPubMedDOI
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DNA methylation-based subclassification of psoriasis in the Chinese Han population.
Zhou F, Shen C, Hsu YH, et al. DNA methylation-based subclassification of psoriasis in the Chinese Han population. Front Med. 2018;12(6):717-725. doi:10.1007/s11684-017-0588-6Google ScholarPubMedDOI
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Association studies of genomic variants with treatment response to risperidone, clozapine, quetiapine and chlorpromazine in the Chinese Han population.
Xu Q, Wu X, Li M, et al. Association studies of genomic variants with treatment response to risperidone, clozapine, quetiapine and chlorpromazine in the Chinese Han population. Pharmacogenomics J. 2016;16(4):357-65. doi:10.1038/tpj.2015.61Google ScholarPubMedDOI
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EDARV370A associated facial characteristics in Uyghur population revealing further pleiotropic effects.
Peng Q, Li J, Tan J, et al. EDARV370A associated facial characteristics in Uyghur population revealing further pleiotropic effects. Hum Genet. 2016;135(1):99-108. doi:10.1007/s00439-015-1618-6Google ScholarPubMedDOI
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Genetic Association of Curative and Adverse Reactions to Tyrosine Kinase Inhibitors in Chinese advanced Non-Small Cell Lung Cancer patients.
Ruan Y, Jiang J, Guo L, et al. Genetic Association of Curative and Adverse Reactions to Tyrosine Kinase Inhibitors in Chinese advanced Non-Small Cell Lung Cancer patients. Sci Rep. 2016;6:23368. doi:10.1038/srep23368Google ScholarPubMedDOI
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The structure of haplotype blocks in the human genome.
Gabriel SB, Schaffner SF, Nguyen H, et al. The structure of haplotype blocks in the human genome. Science. 2002;296(5576):2225-9. doi:10.1126/science.1069424Google ScholarPubMedDOI
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In March of 2020, Broad Institute converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks.

We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap).

Broad Genomics Platform sequences a whole human genome every four minutes.

More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research.

The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery.

In 2021, our sustainability efforts sent more than 80 percent of waste from the Genomics Platform to either a recycling facility or to an incineration plant that generates electricity.

Through Broad's Scientists in the Classroom program, Broad researchers visit every 8th grade classroom in Cambridge each year to talk about genetics and evolution.

Every summer, 18 high school students spend six weeks at Broad working side-by-side with mentors on cutting-edge research.

In November 2022, Broad’s Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th.

By the end of 2022, Broad’s COVID-19 testing lab had processed more than 37 million tests.

Working with Addgene, Broad Institute has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries.

The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Chan School of Public Health to study the genetics of severe mental illness, has recruited more than 42,000 participants in Ethiopia, Kenya, Uganda, and South Africa.

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