Cell Differentiation | Broad Institute

Transcriptomic landscape of the blastema niche in regenerating adult axolotl limbs at single-cell resolution.

Leigh ND, Dunlap GS, Johnson K, et al. Transcriptomic landscape of the blastema niche in regenerating adult axolotl limbs at single-cell resolution. Nat Commun. 2018;9(1):5153. doi:10.1038/s41467-018-07604-0PubMed DOI Google Scholar

Type 2 innate lymphoid cells in the induction and resolution of tissue inflammation.

Wallrapp A, Riesenfeld SJ, Burkett PR, Kuchroo VK. Type 2 innate lymphoid cells in the induction and resolution of tissue inflammation. Immunol Rev. 2018;286(1):53-73. doi:10.1111/imr.12702Google Scholar PubMed DOI

Identification of RIOK2 as a master regulator of human blood cell development.

Ghosh S, Raundhal M, Myers SA, et al. Identification of RIOK2 as a master regulator of human blood cell development. Nat Immunol. 2022;23(1):109-121. doi:10.1038/s41590-021-01079-wPubMed DOI Google Scholar

New Recipes for Myelinating Oligodendrocytes.

Nobuta H, Stockley JH, Rowitch DH. New Recipes for Myelinating Oligodendrocytes. Cell Stem Cell. 2018;23(4):464-465. doi:10.1016/j.stem.2018.09.011PubMed DOI Google Scholar

Colon stroma mediates an inflammation-driven fibroblastic response controlling matrix remodeling and healing.

Jasso GJ, Jaiswal A, Varma M, et al. Colon stroma mediates an inflammation-driven fibroblastic response controlling matrix remodeling and healing. PLoS Biol. 2022;20(1):e3001532. doi:10.1371/journal.pbio.3001532Google Scholar PubMed DOI

IL-1β inflammatory response driven by primary breast cancer prevents metastasis-initiating cell colonization.

Castaño Z, San Juan BP, Spiegel A, et al. IL-1β inflammatory response driven by primary breast cancer prevents metastasis-initiating cell colonization. Nat Cell Biol. 2018;20(9):1084-1097. doi:10.1038/s41556-018-0173-5PubMed DOI Google Scholar

Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome.

Cacchiarelli D, Qiu X, Srivatsan S, et al. Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome. Cell Syst. 2018;7(3):258-268.e3. doi:10.1016/j.cels.2018.07.006PubMed DOI Google Scholar

Modulating Bone Marrow Hematopoietic Lineage Potential to Prevent Bone Metastasis in Breast Cancer.

Ubellacker JM, Baryawno N, Severe N, et al. Modulating Bone Marrow Hematopoietic Lineage Potential to Prevent Bone Metastasis in Breast Cancer. Cancer Res. 2018;78(18):5300-5314. doi:10.1158/0008-5472.CAN-18-0548PubMed DOI Google Scholar

Epigenetic crossroads of the Epstein-Barr virus B-cell relationship.

Frost TC, Gewurz BE. Epigenetic crossroads of the Epstein-Barr virus B-cell relationship. Curr Opin Virol. 2018;32:15-23. doi:10.1016/j.coviro.2018.08.012PubMed DOI Google Scholar

The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.

Khor B, Gagnon JD, Goel G, et al. The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells. Elife. 2015;4. doi:10.7554/eLife.05920PubMed DOI Google Scholar