Watch now Broad is accelerating discovery Broad Institute is a multidisciplinary community of researchers on a mission to improve human health. About us Latest News 11.23.2023 Search algorithm reveals nearly 200 new kinds of CRISPR systems By analyzing bacterial data, researchers have discovered thousands of rare new CRISPR systems that have a range of functions and could enable gene editing, diagnostics, and more. News 11.15.2023 Fairness, listening, and learning: A conversation with Broad’s chief equity officer News 11.14.2023 #WhyIScience Q&A: A computational biologist uses physics to find hidden patterns in cells News 11.13.2023 Gerstner Center for Cancer Diagnostics receives additional commitment from Louis V. Gerstner, Jr., to advance technologies that could transform cancer care All news Our community Join Broad We are a research organization dedicated to better understanding the roots of disease and narrowing the gap between new biological insights and impact for patients. Institute Members Associate and Affiliate Members Professional scientists Early career scientists Administration Affinity groups Partner institutions How we work Research Disease areas Research areas Technology areas Cancer Our scientists are probing the mechanisms of cancer and applying this knowledge to enable precision cancer medicine. /cancer Cardiovascular disease By applying a variety of tools and technologies, researchers here are working to reduce the burden of cardiovascular disease. /cardiovascular-disease Diabetes Our researchers study the cellular roles and physiological impacts of genes associated with type 2 diabetes. /diabetes Infectious disease and the microbiome Researchers across the institute are working to understand infectious diseases, antibiotic resistance, and the human microbiome. /infectious-disease-microbiome Kidney disease Our scientists are cataloging the molecular causes of kidney diseases in order to develop mechanism-based treatments. /kidney-disease Obesity By studying the genetic determinants of body weight, our researchers work to identify targets for future obesity therapies. /obesity Psychiatric disorders We are committed to characterizing psychiatric disorders' molecular roots and turning new findings into new treatments. /psychiatric-disease Rare disease Our scientists search for the risk factors underlying rare genetic diseases to help reveal their biological underpinnings and improve patients' lives. /rare-disease Previous Next Cancer Cardiovascular disease Diabetes Infectious disease and the microbiome Kidney disease Obesity Psychiatric disorders Rare disease Chemical biology and therapeutics science We are fostering a diverse research community engaged in innovative chemical biology and therapeutic research. /chemical-biology-and-therapeutics-science Drug discovery Our Center for the Development of Therapeutics (CDoT) helps scientists advance biological insights to new treatments. /center-development-therapeutics-cdot Genome regulation, cellular circuitry, and epigenomics Our scientists are charting the vast landscape of molecular elements that define and regulate the cell. /genomeregulation-cellcircuitry-epigenomics Immunology Researchers across Broad are defining the immune cells and pathways that regulate physiologic and pathologic processes. /immunology Medical and population genetics An array of scientists here are collaborating to establish genomic variations' roles in human traits and disorders. /medical-population-genetics Metabolism Our researchers aim to decipher the metabolic basis of rare and common human diseases. /metabolism Previous Next Chemical biology and therapeutics science Drug discovery Genome regulation, cellular circuitry, and epigenomics Immunology Medical and population genetics Metabolism Data sciences Members of the Data Sciences Platform build open-source technologies that help researchers everywhere connect to the patients, datasets, and tools they need to do life-changing science. /data-sciences Genetic perturbation The Genetic Perturbation Platform drives the functional study of the genome by developing groundbreaking technologies for perturbing genes at scale. /genetic-perturbation-platform Genomics Genomic scientists here at Broad create foundational resources and study the genomic basis of human traits and diseases. /genomics Imaging Computationally mining cellular images' rich information content can propel discoveries in biology and medicine. /imaging Metabolomics Cells' metabolites reveal unique chemical fingerprints of both normal and pathological disease processes. /metabolomics Proteomics Broad proteomic researchers address important questions in biology, chemistry, and clinical science through collaboration and technology development. /proteomics Previous Next Data sciences Genetic perturbation Genomics Imaging Metabolomics Proteomics Broad Discovery Series: New perspectives on diabetes — the many subtypes of type 2 Miriam Udler and Melina Claussnitzer talk about the many subtypes of type 2 diabetes that genetics has revealed, and what that could mean for patients down the road. Visit the Broad Discovery Center Explore exhibits showcasing how scientists are advancing our understanding of disease. The museum is in the ground floor atrium of the Merkin building at 415 Main Street, Cambridge, MA and is free and open to the public. Learn about summer research programs for students Watch a video to see how high school and undergraduate students have benefitted from doing summer research at Broad. Explore classroom resources Broad Institute offers free high school curriculum guides on genomics, cancer research, and more.