Save the date for the next Stanley Symposium!
September 19-20, 2023
This two-day symposium, chaired by Steve Hyman, Guoping Feng and Ben Neale, brought together leading scientists working on the genetics, neurobiology, and treatment of schizophrenia, bipolar disorder, autism spectrum disorder, and related neuropsychiatric disorders.
The central theme this year was addressing the challenges of turning genetic results that reveal extreme polygenicity into useful biological insights that can help patients. Graduate students and postdoctoral associates are especially welcomed to this symposium in order to build this interdisciplinary field and address the unmet medical needs of patients and their families at a time of great opportunity and urgency.
All sessions were held in the auditorium of the Broad Institute, 415 Main Street, Cambridge MA 02142.
AgendaDay 1 |
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Chair: Ben Neale
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8:15 – 8:50
8:50 – 9:00
9:00 – 9:10
9:10 – 9:40
Common genetic variants associated with Schizophrenia: a Psychiatric Genomics Consortium (PGC) collaboration
Charité University/Massachusetts General Hospital
9:40 – 10:10
Leveraging polygenicity for biological insight from genome-wide association data
Broad Institute
10:10 – 10:40
ENIGMA at 10: What have we learned from a decade of large scale collaborative meta-analysis in neuroimaging
QIMR Berghofer
10:40 – 11:00
11:00 – 11:30
Adaptively using auxiliary data to discover risk genes provides powerful insights into mental illnesses
Carnegie Mellon University
11:30 – 12:00
Interpreting genetic associations with detailed human behavioral data
Harvard T.H. Chan School of Public Health/Broad Institute
12:00 – 12:45
12:45 – 1:15
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1:15 – 1:20
1:20 – 1:35
1:35 – 1:50
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Chair: Morgan Sheng
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1:50 – 2:00
2:00 – 2:30
2:30 – 3:00
3:00 – 3:20
3:20 – 3:50
3:50 – 4:20
Patient selection strategies for clinical trails in monogenic and complex neurological disease
Biogen
4:20 – 4:50
Designing Imaging Biomarkers for Microglia States
Broad Institute
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Boston Children’s Hospital/Broad Institute
4:50 – 5:00
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5:15 – 7:00
McGovern Institute Atrium
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Day 2 |
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Chair: Evan Macosko
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8:15 – 8:50
8:50 – 9:00
9:00 – 9:30
Dissecting Neural Circuits Across Model Systems with Cell Type and Single Cell Resolution
Salk Institute
9:30 – 10:00
10:00 – 10:20
10:20 – 10:50
10:50 – 11:20
11:20 – 11:30
3 Teaser talks for poster session #2
Massachusetts General Hospital
Stanley Center for Psychiatric Research on behalf of the SCHEMA consortium
11:30 – 11:40
11:40 – 11:50
Sunovion Pharmaceuticals Inc.
11:50 – 1:00
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1:00 – 1:05
Keynote Introduction
1:05 – 2:00
Washington University in St Louis
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Chair: Paola Arlotta
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2:00 – 2:10
2:10 – 2:50
Coupling Genotype to Phenotype: Genetic Buffering, Homeostatic Plasticity and a Phenotypic Spectrum
UCSF
2:50 – 3:20
Translating genetic risk of Alzheimer’s disease into mechanisms of disease
VIB-KU Leuven
3:20 – 3:40
Dissecting mechanisms of FMRP in RNA processing using human stem cell models
Broad Institute
3:40 – 4:00
4:00 – 4:20
4:20 – 4:50
4:50 – 5:20
5:20 – 5:30
Concluding remarks from symposium chairs
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