DISCOVAR is a new genome assembler and variant caller for state-of-the-art data. Its inputs are designed to optimize quality while keeping costs low. Currently it takes as input Illumina reads of length 250 or longer — produced on MiSeq or HiSeq 2500 — and from a single PCR-free library. These data enable a level of completeness and continuity that was not previously possible. Please note limitations as described in the FAQ — DISCOVAR will currently process small regions or small genomes, not entire large genomes; DISCOVAR variant calling is under active development and transitioning to VCF.

DISCOVAR is free for non-profit users. We will be charging for commercial use, however DISCOVAR is initially in a free, beta-test period. For more information, see Licensing.

This work has been funded by the National Human Genome Research Institute and National Institute of Allergy and Infectious Diseases.

If you have any trouble building or using DISCOVAR then please follow the steps in our help section.

- DISCOVAR banner and logo designed by Susanna M. Hamilton, Broad Communications.