Melanoma Genomics Portal

Here, we describe a comprehensive genomic analysis of 101 melanoma short-term cultures and cell lines. Using an analytic approach designed to enrich for putative “driver” events, we show that cultured melanoma cells encompass the spectrum of significant genomic alterations present in primary tumors.

Contact: 
Levi Garraway (levi_garraway@dfci.harvard.edu)
Publication Info: 
Title: 
Modeling genomic diversity and tumor dependency in malignant melanoma
Date: 
Cancer Res. 2008 Feb 1;68(3):664-73.
Notes: 
Lin WM, Baker AC, Beroukhim R, Winckler W, Feng W, Marmion JM, Laine E, Greulich H, Tseng H, Gates C, Hodi FS, Dranoff G, Sellers WR, Thomas RK, Meyerson M, Golub TR, Dummer R, Herlyn M, Getz G, Garraway LA.