Head and Neck Cancer Sequencing

Head and neck squamous cell carcinoma (HNSCC) is a common, morbid, and frequently lethal malignancy. To uncover its mutational spectrum, we analyzed whole-exome sequencing data from 74 tumor-normal pairs.

Contact: 
Levi Garraway (levi_garraway@dfci.harvard.edu)
Data Info: 
Description: 

Here is a link to the Head and Neck Cancer Sequencing data in dbGAP

Publication Info: 
Title: 
The mutational landscape of head and neck squamous cell carcinoma
Date: 
Science. 2011 Aug 26;333(6046):1157-60. Epub 2011 Jul 28.
Notes: 
Stransky N, Egloff AM, Tward AD, Kostic AD, Cibulskis K, Sivachenko A, Kryukov GV, Lawrence MS, Sougnez C, McKenna A, Shefler E, Ramos AH, Stojanov P, Carter SL, Voet D, Cortés ML, Auclair D, Berger MF, Saksena G, Guiducci C, Onofrio RC, Parkin M, Romkes M, Weissfeld JL, Seethala RR, Wang L, Rangel-Escareño C, Fernandez-Lopez JC, Hidalgo-Miranda A, Melendez-Zajgla J, Winckler W, Ardlie K, Gabriel SB, Meyerson M, Lander ES, Getz G, Golub TR, Garraway LA, Grandis JR.