MutSig

MutSig (for "Mutation Significance") is a package of tools for analyzing mutation data.  It operates on a cohort of patients and identifies mutations, genes, and other genomic elements predicted to be driver candidates.

Contact: 
http://www.broadinstitute.org/cancer/cga/forum/5
Publication Info: 
Title: 
Mutational heterogeneity in cancer and the search for new cancer-associated genes
Notes: 
Lawrence, M. et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature 499, 214-218 (2013)