Connectivity Map (CMAP)
The Connectivity Map is a collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules and simple pattern-matching algorithms that together enable the discovery of functional connections between drugs, genes and diseases through the transitory feature of common gene-expression changes.
Contact:
Justin Lamb (justin@broadinstitute.org), Aravind Subramanian (aravind@broadinstitute.org), Todd Golub (golub@broadinstitute.org), cmap-help@broadinsititute.org
Data Info:
Publication Info:
Date:
9/29/2006
Notes:
Lamb, et al. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science. 2006 Sep 29;313(5795):1929-35.
Date:
1/7/2007
Notes:
Lamb, J. The Connectivity Map: a new tool for biomedical research. Nat Rev Cancer. 2007 Jan;7(1):54-60.
Tool Info:
Name:
CMAP