Connectivity Map (CMap)

The Connectivity Map (or CMap) is a catalog of gene-expression data collected from human cells treated with chemical compounds and genetic reagents. Computational methods to reduce the number of necessary genomic measurements along with streamlined methodologies enable the current effort to significantly increase the size of the CMap database and along with it, our potential to connect human diseases with the genes that underlie them and the drugs that treat them.

Contact: 
Aravind Subramanian (aravind@broadinstitute.org), Todd Golub (golub@broadinstitute.org), cmap-help@broadinsititute.org
Publication Info: 
Date: 
9/29/2006
Notes: 
Lamb, et al. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science. 2006 Sep 29;313(5795):1929-35.
Date: 
1/7/2007
Notes: 
Lamb, J. The Connectivity Map: a new tool for biomedical research. Nat Rev Cancer. 2007 Jan;7(1):54-60.
Tool Info: