Achilles Project

The goal of the Achilles Project is to create a genome-wide catalog of tumor dependencies to identify vulnerabilities associated with genetic or epigenetic alterations.

Contact: 
Francisca Vazquez vazquez@broadinstitute.org
Data Info: 
Description: 

The Project Achilles data is hosted on the Project Achilles Data Portal.
Here, you can find the Project Achilles data as well as links to files that include annotation information. You can also find links that provide information about the processing of the data files. For additional informaiton about many of the cell lines, please visit the Cancer Cell Line Encyclopedia portal.

Publication Info: 
Title: 
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies
Date: 
9/30/2014
Notes: 
Cowley, Weir, Vazquez et al. Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies. Sci Data. 2014 Sep 30;1:140035. doi: 10.1038/sdata.2014.35. eCollection 2014.
Tool Info: 
Description: 

Links to GenePattern modules and tutorials forĀ Achilles 2 data analysis.