Exocrine Pancreatic Insufficiency (EPI)

Exocrine Pancreatic Insufficiency (EPI) is caused by the progressive lack of pancreatic cells that make digestive enzymes. This causes the inability for the dog to properly digest food and take in nutrients their bodies need. EPI can lead to noticeable weight loss, increased appetite and muscle atrophy. The dogs are diagnosed using a TLI-test where the concentration of a digestion enzyme is measured from a blood sample.

Latest Research Update: A comparison of the genome between healthy and affected German Shepherd has been performed. No clear difference between the two groups was detected so we are now focusing on collecting more EPI affected dogs to strengthen the analysis.

Breeds: German Shepherd, Eurasians, Chow Chow, Rough Coated Collie

Main collaborators: Mia Olsson and Leif Andersson (Uppsala University), Merete Fredholm (University of Copenhagen)

Main contact: Mia Olsson, mia.olsson@imbim.uu.se