Addison’s disease

Also known as hypoadrenocorticism or adrenal insufficiency, Addison’s disease is caused by an insufficient production of adrenal hormones such as cortisol and aldosterone. One of the important functions for these hormones is to regulate the body´s salt balance and response to stress. Symptoms are diffuse but often include vomiting, diarrhea, lethargy and poor appetite. An untreated dog can also suffer from an “Addison crisis” and suddenly collapse.

Latest Research Update: A comparison of the genome of 120 affected and 120 unaffected Standard Poodles has been performed. No clear difference was detected between these two groups so further sample collection and analysis are ongoing.

Breeds: Standard Poodle, Bearded Collies, Portuguese Water Dog

Main collaborators: Anita Oberbauer (University of California, Davis), Åke Hedhammar and Jeanette Hansson (Swedish University of Agricultural Science) Olle Kämpe and Katarina Tengvall (Uppsala University)

Main contact: Jeanette Hansson, Jeanette.Hanson@slu.se

*Note - sample collection also at UCD and SUAS