Genetic Analysis Platform

The Genetic Analysis Platform collaborates with scientists at the Broad and across the world to identify and characterize patterns of genetic variation and gene expression. These patterns can yield a deeper understanding of how genetic factors influence disease risk and treatment outcomes in a wide range of human diseases, including type 2 diabetes, Crohn's disease, schizophrenia, and cancer, among many others.

Over the past several years, the platform has been a leading contributor to major projects such as the International Haplotype Map Project, The Cancer Genome Atlas, the 1,000 Genomes Project, the Genes and Environment Initiative, and served as a national genotyping center under a NIH/NCRR program.

Genetic Analysis Platform (GAP) scientists are experts in a wide range of genomic technologies and technology platforms, including genotyping, gene expression and directed resequencing, and routinely apply these technologies to studies of both human and non-human samples. In addition, teams of platform researchers work to test out emerging genetic technologies, develop informatics tools and infrastructure to enhance scientific research, and coordinate large-scale projects involving collaborators both within and beyond the Broad.

The Genetic Analysis Platform (GAP) is led by Wendy Winckler, who brings expertise in human and cancer genetics as well as the management of large-scale genomic projects. Assistant Director of Operations Andrew Crenshaw manages the SNP genotyping, gene expression, and directed sequencing production. Assistant Director of Informatics George Grant supervises informatics development for the platform.

Questions? Please use the GAP inquiry form to get in touch.