Canine Genomics & Disease Publications
Dog Genome Paper:
Lindblad-Toh, K, et al. (2005). Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 438, 803-819.
Degenerative myelopathy:
Genome-wide association analysis reveals a SOD1 mutation in canine degenerative myelopathy that resembles amyotrophic lateral sclerosis. (2009) PNAS USA 106:2794-9
OCD:
A canine chromosome 7 locus confers compulsive disorder susceptibility. (2010) Mol Psychiatry. 15:8-10.
Familial Shar Pei Fever (FSF):
A Novel Unstable Duplication Upstream of HAS2 Predisposes to a Breed-Defining Skin Phenotype and a Periodic Fever Syndrome in Chinese Shar-Pei Dogs, (2011) PLoS Genet. 7: e1001332.
Toller diseases:
Genome-wide association mapping identifies multiple loci for a canine SLE-related disease complex (2010) Nat Genet. 42:250-4
Dermoid Sinus:
Duplication of FGF3, FGF4, FGF19, and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback dogs. Nature Genetics DOI: 10.1038/ng.2007.4
Hairlessness/Canine Ecodermal Dysplasia:
A Mutation in Hairless Dogs Implicates FOXI3 in Ectodermal Development. Science DOI: 10.1126/science.1162525
Progressive cone rod dystrophy:
A deletion in nephronophthisis 4 (NPHP4) is associated with recessive cone-rod dystrophy in standard wire-haired dachshund. Genome Res. doi:10.1101/gr.074302.107
White Coat Color:
Efficient mapping of mendelian traits in dogs through genome-wide association. Nature Genetics DOI:10.1038/ng.2007.10
