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The RNAi Consortium shRNA Library

The RNAi Consortium, or TRC, is a public-private effort based at the Broad whose mission is to create a shRNA library as well to validate tools and methods that will enable the scientific community to use RNAi to determine the function of human and mouse genes. The reagents are composed of short hairpin sequences carried in lentiviral vectors arrayed in 96-well plates.

Library Distribution

The TRC shRNA library is distributed as bacterial glycerol stocks, plasmid DNA or lentiviral particles by Sigma-Aldrich and as bacterial glycerol stocks by Open Biosystems. The Broad RNAi platform does not directly distribute the TRC library.

Search for Available TRC shRNA Constructs

Sigma-Aldrich
Open Biosystems
TRC Library Database

Protocols and Related Information

For protocols and other useful resources, please visit our TRC Library Database

Questions

Any questions? Please email us at trc_info@broadinstitute.org