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2007
Characterizing the cancer genome in lung adenocarcinomaWeir, Barbara A., Woo Michele S., Getz Gad, Perner Sven, Ding Li, Beroukhim Rameen, Lin William M., Province Michael A., Kraja Aldi, Johnson Laura A., Shah Kinjal, Sato Mitsuo, Thomas Roman K., Barletta Justine A., Borecki Ingrid B., Broderick Stephen, and Chang Andre Nature, 2007/12/06/, Volume 450, Issue 7171, p.893 - 8, (2007) Read More / View Supplemental Materials
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Characterizing the cancer genome in lung adenocarcinoma.Weir, BA, Woo MS, Getz G., Perner S., Ding L., Beroukhim R., Lin WM, Province MA, Kraja A., Johnson LA, Shah K., Sato M., Thomas RK, Barletta JA, Borecki IB, Broderick S., Chang AC, Chiang DY, Chirieac LR, Cho J., et al. Nature, 2007/12/06, Volume 450, Issue 7171, p.893-8, (2007) Read More / View Supplemental Materials
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Distinguishing protein-coding and noncoding genes in the human genome.Clamp, M., Fry B., Kamal M., Xie X., Cuff J., Lin MF, Kellis M., Lindblad-Toh K., and Lander E. S. Proceedings of the National Academy of Sciences of the United States of America, 2007/12/04, Volume 104, Issue 49, p.19428-33, (2007) Read More / View Supplemental Materials
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28-way vertebrate alignment and conservation track in the UCSC Genome Browser.Miller, W., Rosenbloom K., Hardison RC, Hou M., Taylor J., Raney B., Burhans R., King DC, Baertsch R., Blankenberg D., Kosakovsky Pond SL, Nekrutenko A., Giardine B., Harris RS, Tyekucheva S., Diekhans M., Pringle TH, Murphy WJ, Lesk A., Weinstock GM, et al. Genome research, 2007/12/01, Volume 17, Issue 12, p.1797-808, (2007) Read More / View Supplemental Materials
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GSEA-P: a desktop application for Gene Set Enrichment Analysis.Subramanian, A., Kuehn H., Gould J., Tamayo P., and Mesirov J. P. Bioinformatics (Oxford, England), 2007/12/01, Volume 23, Issue 23, p.3251-3, (2007) Read More / View Supplemental Materials
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Identification of driver and passenger mutations of FLT3 by high-throughput DNA sequence analysis and functional assessment of candidate alleles.Fröhling, S., Scholl C., Levine RL, Loriaux M., Boggon TJ, Bernard OA, Berger R., Döhner H., Döhner K., Ebert BL, Teckie S., Golub T. R., Jiang J., Schittenhelm MM, Lee BH, Griffin JD, Stone RM, Heinrich MC, Deininger MW, Druker BJ, et al. Cancer cell, 2007/12/01, Volume 12, Issue 6, p.501-13, (2007) Read More / View Supplemental Materials
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N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli.Mukherjee, S., Robinson CA, Howe AG, Mazor T., Wood PA, Urgaonkar S., Hebert AM, Raychaudhuri D., and Shaw JT Bioorganic & medicinal chemistry letters, 2007/12/01, Volume 17, Issue 23, p.6651-5, (2007) Read More / View Supplemental Materials
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Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution.Keshishian, H., Addona T., Burgess M., Kuhn E., and Carr SA Molecular & cellular proteomics : MCP, 2007/12/01, Volume 6, Issue 12, p.2212-29, (2007) Read More / View Supplemental Materials
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Revisiting the protein-coding gene catalog of Drosophila melanogaster using 12 fly genomes.Lin, MF, Carlson JW, Crosby MA, Matthews BB, Yu C., Park S., Wan KH, Schroeder AJ, Gramates LS, St Pierre SE, Roark M., Wiley KL Jr, Kulathinal RJ, Zhang P., Myrick KV, Antone JV, Celniker SE, Gelbart WM, and Kellis M. Genome research, 2007/12/01, Volume 17, Issue 12, p.1823-36, (2007) Read More / View Supplemental Materials
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Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes.Stark, A., Kheradpour P., Parts L., Brennecke J., Hodges E., Hannon GJ, and Kellis M. Genome research, 2007/12/01, Volume 17, Issue 12, p.1865-79, (2007) Read More / View Supplemental Materials
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Two independent alleles at 6q23 associated with risk of rheumatoid arthritis.Plenge, RM, Cotsapas C., Davies L., Price AL, de Bakker PI, Maller J., Pe'er I., Burtt NP, Blumenstiel B., DeFelice M., Parkin M., Barry R., Winslow W., Healy C., Graham RR, Neale BM, Izmailova E., Roubenoff R., Parker AN, Glass R., et al. Nature genetics, 2007/12/01, Volume 39, Issue 12, p.1477-82, (2007) Read More / View Supplemental Materials
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Subclass mapping: identifying common subtypes in independent disease data sets.Hoshida, Y., Brunet JP, Tamayo P., Golub T. R., and Mesirov J. P. PloS one, 2007/11/21, Volume 2, Issue 11, p.e1195, (2007) Read More / View Supplemental Materials
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High expression of lymphocyte-associated genes in node-negative HER2+ breast cancers correlates with lower recurrence ratesAlexe, Gabriela, Dalgin Gul S., Scanfeld Daniel, Tamayo Pablo, Mesirov Jill P., DeLisi Charles, Harris Lyndsay, Barnard Nicola, Martel Maritza, Levine Arnold J., Ganesan Shridar, and Bhanot Gyan Cancer Research, 2007/11/15/, Volume 67, Issue 22, p.10669 - 76, (2007) Read More / View Supplemental Materials
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High expression of lymphocyte-associated genes in node-negative HER2+ breast cancers correlates with lower recurrence rates.Alexe, G., Dalgin GS, Scanfeld D., Tamayo P., Mesirov J. P., Delisi C., Harris L., Barnard N., Martel M., Levine AJ, Ganesan S., and Bhanot G. Cancer research, 2007/11/15, Volume 67, Issue 22, p.10669-76, (2007) Read More / View Supplemental Materials
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Altered microRNA expression in human heart disease.Ikeda, S., Kong SW, Lu J., Bisping E., Zhang H., Allen PD, Golub T. R., Pieske B., and Pu WT Physiological genomics, 2007/11/14, Volume 31, Issue 3, p.367-73, (2007) Read More / View Supplemental Materials
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Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures.Stark, A., Lin MF, Kheradpour P., Pedersen JS, Parts L., Carlson JW, Crosby MA, Rasmussen MD, Roy S., Deoras AN, Ruby JG, Brennecke J., curators Harvard FlyBase, Berkeley Drosophila Genome Project, Hodges E., Hinrichs AS, Caspi A., Paten B., Park SW, Han MV, et al. Nature, 2007/11/08, Volume 450, Issue 7167, p.219-32, (2007) Read More / View Supplemental Materials
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Evolution of genes and genomes on the Drosophila phylogeny.Drosophila 12 Genomes, Consortium, Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B., Markow TA, Kaufman TC, Kellis M., Gelbart W., Iyer VN, Pollard DA, Sackton TB, Larracuente AM, Singh ND, Abad JP, Abt DN, Adryan B., Aguade M., Akashi H., et al. Nature, 2007/11/08, Volume 450, Issue 7167, p.203-18, (2007) Read More / View Supplemental Materials
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Identification of prostate cancer modifier pathways using parental strain expression mapping.Xu, Q., Majumder PK, Ross K., Shim Y., Golub T. R., Loda M., and Sellers WR Proceedings of the National Academy of Sciences of the United States of America, 2007/11/06, Volume 104, Issue 45, p.17771-6, (2007) Read More / View Supplemental Materials
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Efficient mapping of mendelian traits in dogs through genome-wide association.Karlsson, EK, Baranowska I., Wade CM, Salmon Hillbertz NH, Zody MC, Anderson N., Biagi TM, Patterson N., Pielberg GR, Kulbokas EJ 3rd, Comstock KE, Keller ET, Mesirov J. P., von Euler H., Kämpe O., Hedhammar A., Lander E. S., Andersson G., Andersson L., and Lindblad-Toh K. Nature genetics, 2007/11/01, Volume 39, Issue 11, p.1321-8, (2007) Read More / View Supplemental Materials
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Genome-wide detection and characterization of positive selection in human populations.Sabeti, PC, Varilly P., Fry B., Lohmueller J., Hostetter E., Cotsapas C., Xie X., Byrne EH, McCarroll SA, Gaudet R., Schaffner SF, Lander E. S., International HapMap Consortium, Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, Belmont JW, et al. Nature, 2007/10/18, Volume 449, Issue 7164, p.913-8, (2007) Read More / View Supplemental Materials
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Lesional gene expression profiling in cutaneous T-cell lymphoma reveals natural clusters associated with disease outcomeShin, Jessica, Monti Stefano, Aires Daniel J., Duvic Madeleine, Golub Todd, Jones David A., and Kupper Thomas S. Blood, 2007/10/15/, Volume 110, Issue 8, p.3015 - 27, (2007) Read More / View Supplemental Materials
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Identification of novel epoxide inhibitors of hepatitis C virus replication using a high-throughput screen.Peng, LF, Kim SS, Matchacheep S., Lei X., Su S., Lin W., Runguphan W., Choe WH, Sakamoto N., Ikeda M., Kato N., Beeler AB, Porco JA Jr, Schreiber SL, and Chung RT Antimicrobial agents and chemotherapy, 2007/10/01, Volume 51, Issue 10, p.3756-9, (2007) Read More / View Supplemental Materials
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MicroRNAs and cancerCowland, Jack B., Hother Christoffer, and Gr APMIS: Acta Pathologica, Microbiologica, Et Immunologica Scandinavica, 2007/10//, Volume 115, Issue 10, p.1090 - 106, (2007) Read More / View Supplemental Materials
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Diastereoselective synthesis of gamma-lactams by a one-pot, four-component reaction.Wei, J., and Shaw JT Organic letters, 2007/09/27, Volume 9, Issue 20, p.4077-80, (2007) Read More / View Supplemental Materials
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TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.Plenge, RM, Seielstad M., Padyukov L., Lee AT, Remmers EF, Ding B., Liew A., Khalili H., Chandrasekaran A., Davies LR, Li W., Tan AK, Bonnard C., Ong RT, Thalamuthu A., Pettersson S., Liu C., Tian C., Chen WV, Carulli JP, et al. The New England journal of medicine, 2007/09/20, Volume 357, Issue 12, p.1199-209, (2007) Read More / View Supplemental Materials
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Detecting binding interactions using microarrays of natural product extracts.Schmitz, K., Haggarty SJ, McPherson OM, Clardy J., and Koehler AN Journal of the American Chemical Society, 2007/09/19, Volume 129, Issue 37, p.11346-7, (2007) Read More / View Supplemental Materials
Fluorous-based small-molecule microarrays for the discovery of histone deacetylase inhibitors.Vegas, AJ, Bradner JE, Tang W., McPherson OM, Greenberg EF, Koehler AN, and Schreiber SL Angewandte Chemie (International ed. in English), 2007/09/17, Volume 46, Issue 42, p.7960-4, (2007) Read More / View Supplemental Materials
Comment on "The consensus coding sequences of human breast and colorectal cancers".Getz, G., Höfling H., Mesirov J. P., Golub T. R., Meyerson M., Tibshirani R., and Lander E. S. Science (New York, N.Y.), 2007/09/14, Volume 317, Issue 5844, p.1500, (2007) Read More / View Supplemental Materials
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The Fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization.Cuomo, CA, Güldener U., Xu JR, Trail F., Turgeon BG, Di Pietro A., Walton JD, Ma LJ, Baker SE, Rep M., Adam G., Antoniw J., Baldwin T., Calvo S., Chang YL, DeCaprio D., Gale LR, Gnerre S., Goswami RS, Hammond-Kosack K., et al. Science (New York, N.Y.), 2007/09/07, Volume 317, Issue 5843, p.1400-2, (2007) Read More / View Supplemental Materials
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Natural history and evolutionary principles of gene duplication in fungi.Wapinski, I., Pfeffer A., Friedman N., and Regev A. Nature, 2007/09/06, Volume 449, Issue 7158, p.54-61, (2007) Read More / View Supplemental Materials
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Common genetic variation in eight genes of the GH/IGF1 axis does not contribute to adult height variation.Lettre, G., Butler JL, Ardlie KG, and Hirschhorn JN Human genetics, 2007/09/01, Volume 122, Issue 2, p.129-39, (2007) Read More / View Supplemental Materials
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Conrad: gene prediction using conditional random fields.DeCaprio, D., Vinson JP, Pearson MD, Montgomery P., Doherty M., and Galagan JE Genome research, 2007/09/01, Volume 17, Issue 9, p.1389-98, (2007) Read More / View Supplemental Materials
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New models of collaboration in genome-wide association studies: the Genetic Association Information Network.GAIN Collaborative Research, Group, Manolio TA, Rodriguez LL, Brooks L., Abecasis G., Collaborative Association Study of Psoriasis, Ballinger D., Daly M., Donnelly P., Faraone SV, International Multi-Center ADHD Genetics Project, Frazer K., Gabriel S., Gejman P., Molecular Genetics of Schizophrenia Collaboration, Guttmacher A., Harris EL, Insel T., Kelsoe JR, Bipolar Genome Study, et al. Nature genetics, 2007/09/01, Volume 39, Issue 9, p.1045-51, (2007) Read More / View Supplemental Materials
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Risk alleles for multiple sclerosis identified by a genomewide study.International Multiple Sclerosis Genetics, Consortium, Hafler DA, Compston A., Sawcer S., Lander E. S., Daly M. J., De Jager PL, de Bakker PI, Gabriel SB, Mirel DB, Ivinson AJ, Pericak-Vance MA, Gregory SG, Rioux JD, McCauley JL, Haines JL, Barcellos LF, Cree B., Oksenberg JR, and Hauser SL The New England journal of medicine, 2007/08/30, Volume 357, Issue 9, p.851-62, (2007) Read More / View Supplemental Materials
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The AP1-dependent secretion of galectin-1 by Reed Sternberg cells fosters immune privilege in classical Hodgkin lymphomaJuszczynski, Przemyslaw, Ouyang Jing, Monti Stefano, Rodig Scott J., Takeyama Kunihiko, Abramson Jeremy, Chen Wen, Kutok Jeffery L., Rabinovich Gabriel A., and Shipp Margaret A. Proceedings of the National Academy of Sciences of the United States of America, 2007/08/07/, Volume 104, Issue 32, p.13134 - 9, (2007) Read More / View Supplemental Materials
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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells.Mikkelsen, TS, Ku M., Jaffe DB, Issac B., Lieberman E., Giannoukos G., Alvarez P., Brockman W., Kim TK, Koche RP, Lee W., Mendenhall E., O'Donovan A., Presser A., Russ C., Xie X., Meissner A., Wernig M., Jaenisch R., Nusbaum C., et al. Nature, 2007/08/02, Volume 448, Issue 7153, p.553-60, (2007) Read More / View Supplemental Materials
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Analysis of breast cancer progression using principal component analysis and clustering.Alexe, G., Dalgin GS, Ganesan S., Delisi C., and Bhanot G. Journal of biosciences, 2007/08/01, Volume 32, Issue 5, p.1027-39, (2007) Read More / View Supplemental Materials
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Dual modes of natural selection on upstream open reading frames.Neafsey, DE, and Galagan JE Molecular biology and evolution, 2007/08/01, Volume 24, Issue 8, p.1744-51, (2007) Read More / View Supplemental Materials
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Evolutionarily conserved optimization of amino acid biosynthesis.Perlstein, EO, de Bivort BL, Kunes S., and Schreiber SL Journal of molecular evolution, 2007/08/01, Volume 65, Issue 2, p.186-96, (2007) Read More / View Supplemental Materials
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Image-based chemical screening.Carpenter, AE Nature chemical biology, 2007/08/01, Volume 3, Issue 8, p.461-5, (2007) Read More / View Supplemental Materials
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Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI.Nieland, TJ, Shaw JT, Jaipuri FA, Maliga Z., Duffner JL, Koehler AN, and Krieger M. Journal of lipid research, 2007/08/01, Volume 48, Issue 8, p.1832-45, (2007) Read More / View Supplemental Materials
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Positive selection for unpreferred codon usage in eukaryotic genomes.Neafsey, DE, and Galagan JE BMC evolutionary biology, 2007/07/18, Volume 7, p.119, (2007) Read More / View Supplemental Materials
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TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohortDemichelis, F., Fall K., Perner S., and Andr Oncogene, 2007/07/05/, Volume 26, Issue 31, p.4596 - 9, (2007) Read More / View Supplemental Materials
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Automatic genome-wide reconstruction of phylogenetic gene trees.Wapinski, I., Pfeffer A., Friedman N., and Regev A. Bioinformatics (Oxford, England), 2007/07/01, Volume 23, Issue 13, p.i549-58, (2007) Read More / View Supplemental Materials
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Copy-number variation and association studies of human disease.McCarroll, SA, and Altshuler DM Nature genetics, 2007/07/01, Volume 39, Issue 7 Suppl, p.S37-42, (2007) Read More / View Supplemental Materials
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Ligand design by a combinatorial approach based on modeling and experiment: application to HLA-DR4.Evensen, E., Joseph-McCarthy D., Weiss GA, Schreiber SL, and Karplus M. Journal of computer-aided molecular design, 2007/07/01, Volume 21, Issue 7, p.395-418, (2007) Read More / View Supplemental Materials
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Rethinking relationships between natural products.Schreiber, SL Nature chemical biology, 2007/07/01, Volume 3, Issue 7, p.352, (2007) Read More / View Supplemental Materials
Quantifying fitness distributions and phenotypic relationships in recombinant yeast populations.Perlstein, EO, Deeds EJ, Ashenberg O., Shakhnovich EI, and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2007/06/19, Volume 104, Issue 25, p.10553-8, (2007) Read More / View Supplemental Materials
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Integrative genomic approaches identify IKBKE as a breast cancer oncogene.Boehm, JS, Zhao JJ, Yao J., Kim SY, Firestein R., Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S., Richardson AL, Greulich H., Stewart CJ, Mulvey LA, Shen RR, Ambrogio L., Hirozane-Kishikawa T., Hill DE, Vidal M., Meyerson M., Grenier JK, et al. Cell, 2007/06/15, Volume 129, Issue 6, p.1065-79, (2007) Read More / View Supplemental Materials
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.ENCODE Project, Consortium, Birney E., Stamatoyannopoulos JA, Dutta A., Guigó R., Gingeras TR, Margulies EH, Weng Z., Snyder M., Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S., Koch CM, Asthana S., Malhotra A., Adzhubei I., Greenbaum JA, Andrews RM, et al. Nature, 2007/06/14, Volume 447, Issue 7146, p.799-816, (2007) Read More / View Supplemental Materials
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Synthesis of diverse lactam carboxamides leading to the discovery of a new transcription-factor inhibitor.Ng, PY, Tang Y., Knosp WM, Stadler HS, and Shaw JT Angewandte Chemie (International ed. in English), 2007/06/14, Volume 46, Issue 28, p.5352-5, (2007) Read More / View Supplemental Materials
Synthesis of kaempferitrin.Urgaonkar, S., and Shaw JT The Journal of organic chemistry, 2007/06/08, Volume 72, Issue 12, p.4582-5, (2007) Read More / View Supplemental Materials
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Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome.Margulies, EH, Cooper GM, Asimenos G., Thomas DJ, Dewey CN, Siepel A., Birney E., Keefe D., Schwartz AS, Hou M., Taylor J., Nikolaev S., Montoya-Burgos JI, Löytynoja A., Whelan S., Pardi F., Massingham T., Brown JB, Bickel P., Holmes I., et al. Genome research, 2007/06/01, Volume 17, Issue 6, p.760-74, (2007) Read More / View Supplemental Materials
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Genetic determinants of QT interval variation and sudden cardiac death.Newton-Cheh, C., and Shah R. Current opinion in genetics & development, 2007/06/01, Volume 17, Issue 3, p.213-21, (2007) Read More / View Supplemental Materials
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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.and of Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, Novartis Institutes BioMedical Rese, Saxena R., Voight BF, Lyssenko V., Burtt NP, de Bakker PI, Chen H., Roix JJ, Kathiresan S., Hirschhorn JN, Daly M. J., Hughes TE, Groop L., Altshuler D., Almgren P., Florez JC, Meyer J., Ardlie K., Bengtsson Boström K., Isomaa B., et al. Science (New York, N.Y.), 2007/06/01, Volume 316, Issue 5829, p.1331-6, (2007) Read More / View Supplemental Materials
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Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.Sarkar, S., Perlstein EO, Imarisio S., Pineau S., Cordenier A., Maglathlin RL, Webster JA, Lewis TA, O'Kane CJ, Schreiber SL, and Rubinsztein DC Nature chemical biology, 2007/06/01, Volume 3, Issue 6, p.331-8, (2007) Read More / View Supplemental Materials
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Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences.Mikkelsen, TS, Wakefield MJ, Aken B., Amemiya CT, Chang JL, Duke S., Garber M., Gentles AJ, Goodstadt L., Heger A., Jurka J., Kamal M., Mauceli E., Searle SM, Sharpe T., Baker ML, Batzer MA, Benos PV, Belov K., Clamp M., et al. Nature, 2007/05/10, Volume 447, Issue 7141, p.167-77, (2007) Read More / View Supplemental Materials
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Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate.Lowery, DM, Clauser KR, Hjerrild M., Lim D., Alexander J., Kishi K., Ong SE, Gammeltoft S., Carr SA, and Yaffe MB The EMBO journal, 2007/05/02, Volume 26, Issue 9, p.2262-73, (2007) Read More / View Supplemental Materials
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Enrichment of longevity phenotype in mtDNA haplogroups D4b2b, D4a, and D5 in the Japanese population.Alexe, G., Fuku N., Bilal E., Ueno H., Nishigaki Y., Fujita Y., Ito M., Arai Y., Hirose N., Bhanot G., and Tanaka M. Human genetics, 2007/05/01, Volume 121, Issue 3-4, p.347-56, (2007) Read More / View Supplemental Materials
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Genetic model testing and statistical power in population-based association studies of quantitative traits.Lettre, G., Lange C., and Hirschhorn JN Genetic epidemiology, 2007/05/01, Volume 31, Issue 4, p.358-62, (2007) Read More / View Supplemental Materials
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Impaired microRNA processing enhances cellular transformation and tumorigenesis.Kumar, MS, Lu J., Mercer KL, Golub T. R., and Jacks T. Nature genetics, 2007/05/01, Volume 39, Issue 5, p.673-7, (2007) Read More / View Supplemental Materials
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Impaired microRNA processing enhances cellular transformation and tumorigenesisKumar, Madhu S., Lu Jun, Mercer Kim L., Golub Todd R., and Jacks Tyler Nature Genetics, 2007/05//, Volume 39, Issue 5, p.673 - 7, (2007) Read More / View Supplemental Materials
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Synthesis and stereochemical assignment of brasilibactin A.Mitchell, JM, and Shaw JT Organic letters, 2007/04/26, Volume 9, Issue 9, p.1679-81, (2007) Read More / View Supplemental Materials
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Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites.Xie, X., Mikkelsen TS, Gnirke A., Lindblad-Toh K., Kellis M., and Lander E. S. Proceedings of the National Academy of Sciences of the United States of America, 2007/04/24, Volume 104, Issue 17, p.7145-50, (2007) Read More / View Supplemental Materials
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The maternal-zygotic transition: death and birth of RNAs.Schier, AF Science (New York, N.Y.), 2007/04/20, Volume 316, Issue 5823, p.406-7, (2007) Read More / View Supplemental Materials
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Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.Graham, RR, Kyogoku C., Sigurdsson S., Vlasova IA, Davies LR, Baechler EC, Plenge RM, Koeuth T., Ortmann WA, Hom G., Bauer JW, Gillett C., Burtt N., Cunninghame Graham DS, Onofrio R., Petri M., Gunnarsson I., Svenungsson E., Rönnblom L., Nordmark G., et al. Proceedings of the National Academy of Sciences of the United States of America, 2007/04/17, Volume 104, Issue 16, p.6758-63, (2007) Read More / View Supplemental Materials
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Prospective isolation and global gene expression analysis of definitive and visceral endoderm.Sherwood, RI, Jitianu C., Cleaver O., Shaywitz DA, Lamenzo JO, Chen AE, Golub T. R., and Melton DA Developmental biology, 2007/04/15, Volume 304, Issue 2, p.541-55, (2007) Read More / View Supplemental Materials
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Genomics: global views of leukaemia.Golub, T. R. Nature, 2007/04/12, Volume 446, Issue 7137, p.739-40, (2007) Read More / View Supplemental Materials
Metagene projection for cross-platform, cross-species characterization of global transcriptional statesTamayo, Pablo, Scanfeld Daniel, Ebert Benjamin L., Gillette Michael A., Roberts Charles W. M., and Mesirov Jill P. Proceedings of the National Academy of Sciences of the United States of America, 2007/04/03/, Volume 104, Issue 14, p.5959 - 64, (2007) Read More / View Supplemental Materials
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Metagene projection for cross-platform, cross-species characterization of global transcriptional states.Tamayo, P., Scanfeld D., Ebert BL, Gillette MA, Roberts CW, and Mesirov J. P. Proceedings of the National Academy of Sciences of the United States of America, 2007/04/03, Volume 104, Issue 14, p.5959-64, (2007) Read More / View Supplemental Materials
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Genetic basis of individual differences in the response to small-molecule drugs in yeast.Perlstein, EO, Ruderfer DM, Roberts DC, Schreiber SL, and Kruglyak L. Nature genetics, 2007/04/01, Volume 39, Issue 4, p.496-502, (2007) Read More / View Supplemental Materials
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Identification of a small-molecule inhibitor of class Ia PI3Ks with cell-based screening.Yang, J., Shamji A., Matchacheep S., and Schreiber SL Chemistry & biology, 2007/04/01, Volume 14, Issue 4, p.371-7, (2007) Read More / View Supplemental Materials
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Population genetic tools: application to cancer.Gabriel, S. Seminars in oncology, 2007/04/01, Volume 34, Issue 2 Suppl 1, p.S21-4, (2007) Read More / View Supplemental Materials
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Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma.Stegmaier, K., Wong JS, Ross KN, Chow KT, Peck D., Wright RD, Lessnick SL, Kung AL, and Golub T. R. PLoS medicine, 2007/04/01, Volume 4, Issue 4, p.e122, (2007) Read More / View Supplemental Materials
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Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcomaStegmaier, Kimberly, Wong Jenny S., Ross Kenneth N., Chow Kwan T., Peck David, Wright Renee D., Lessnick Stephen L., Kung Andrew L., and Golub Todd R. PLoS Medicine, 2007/04//, Volume 4, Issue 4, p.e122 - e122, (2007) Read More / View Supplemental Materials
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PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.Sancak, Y., Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E., Carr SA, and Sabatini DM Molecular cell, 2007/03/23, Volume 25, Issue 6, p.903-15, (2007) Read More / View Supplemental Materials
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Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes.Winckler, W., Weedon MN, Graham RR, McCarroll SA, Purcell S., Almgren P., Tuomi T., Gaudet D., Boström KB, Walker M., Hitman G., Hattersley AT, McCarthy MI, Ardlie KG, Hirschhorn JN, Daly M. J., Frayling TM, Groop L., and Altshuler D. Diabetes, 2007/03/01, Volume 56, Issue 3, p.685-93, (2007) Read More / View Supplemental Materials
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High-throughput oncogene mutation profiling in human cancer.Thomas, RK, Baker AC, Debiasi RM, Winckler W., LaFramboise T., Lin WM, Wang M., Feng W., Zander T., MacConaill L., Lee JC, Nicoletti R., Hatton C., Goyette M., Girard L., Majmudar K., Ziaugra L., Wong KK, Gabriel S., Beroukhim R., et al. Nature genetics, 2007/03/01, Volume 39, Issue 3, p.347-51, (2007) Read More / View Supplemental Materials
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A second major histocompatibility complex susceptibility locus for multiple sclerosis.Yeo, TW, De Jager PL, Gregory SG, Barcellos LF, Walton A., Goris A., Fenoglio C., Ban M., Taylor CJ, Goodman RS, Walsh E., Wolfish CS, Horton R., Traherne J., Beck S., Trowsdale J., Caillier SJ, Ivinson AJ, Green T., Pobywajlo S., et al. Annals of neurology, 2007/03/01, Volume 61, Issue 3, p.228-36, (2007) Read More / View Supplemental Materials
Abstract
Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomasPolo, Jose M., Juszczynski Przemyslaw, Monti Stefano, Cerchietti Leandro, Ye Kenny, Greally John M., Shipp Margaret, and Melnick Ari Proceedings of the National Academy of Sciences of the United States of America, 2007/02/27/, Volume 104, Issue 9, p.3207 - 12, (2007) Read More / View Supplemental Materials
Abstract
The mammalian epigenome.Bernstein, BE, Meissner A., and Lander E. S. Cell, 2007/02/23, Volume 128, Issue 4, p.669-81, (2007) Read More / View Supplemental Materials
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Synthesis and cellular profiling of diverse organosilicon small molecules.Franz, AK, Dreyfuss PD, and Schreiber SL Journal of the American Chemical Society, 2007/02/07, Volume 129, Issue 5, p.1020-1, (2007) Read More / View Supplemental Materials
A pipeline for ligand discovery using small-molecule microarrays.Duffner, JL, Clemons PA, and Koehler AN Current opinion in chemical biology, 2007/02/01, Volume 11, Issue 1, p.74-82, (2007) Read More / View Supplemental Materials
Abstract
Semiautomated multiplexed quantum dot-based in situ hybridization and spectral deconvolution.Byers, RJ, Di Vizio D., O'connell F., Tholouli E., Levenson RM, Gossage K., Twomey D., Yang Y., Benedettini E., Rose J., Ligon KL, Finn SP, Golub T. R., and Loda M. The Journal of molecular diagnostics : JMD, 2007/02/01, Volume 9, Issue 1, p.20-9, (2007) Read More / View Supplemental Materials
Abstract
Sleep-related epilepsy in the A/J mouse.Strohl, KP, Gallaugher L., Lynn A., Friedman L., Hill A., Singer JB, Lander E. S., and Nadeau J. Sleep, 2007/02/01, Volume 30, Issue 2, p.169-76, (2007) Read More / View Supplemental Materials
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IFN-alpha-stimulated genes and Epstein-Barr virus gene expression distinguish WHO type II and III nasopharyngeal carcinomas.Pegtel, DM, Subramanian A., Meritt D., Tsai CH, Sheen TS, Golub T. R., and Thorley-Lawson DA Cancer research, 2007/01/15, Volume 67, Issue 2, p.474-81, (2007) Read More / View Supplemental Materials
Abstract
Breast cancer stratification from analysis of micro-array data of micro-dissected specimens.Alexe, G., Dalgin GS, Scanfeld D., Tamayo P., Mesirov J. P., Ganesan S., Delisi C., and Bhanot G. Genome informatics. International Conference on Genome Informatics, 2007/01/01, Volume 18, p.130-40, (2007) Read More / View Supplemental Materials
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A cell-based, high-throughput screen for small molecule regulators of hepatitis C virus replication.Kim, SS, Peng LF, Lin W., Choe WH, Sakamoto N., Kato N., Ikeda M., Schreiber SL, and Chung RT Gastroenterology, 2007/01/01, Volume 132, Issue 1, p.311-20, (2007) Read More / View Supplemental Materials
Abstract
The Connectivity Map: a new tool for biomedical research.Lamb, J. Nature reviews. Cancer, 2007/01/01, Volume 7, Issue 1, p.54-60, (2007) Read More / View Supplemental Materials
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A genome-wide map of diversity in Plasmodium falciparum.Volkman, SK, Sabeti PC, DeCaprio D., Neafsey DE, Schaffner SF, Milner DA Jr, Daily JP, Sarr O., Ndiaye D., Ndir O., Mboup S., Duraisingh MT, Lukens A., Derr A., Stange-Thomann N., Waggoner S., Onofrio R., Ziaugra L., Mauceli E., Gnerre S., et al. Nature genetics, 2007/01/01, Volume 39, Issue 1, p.113-9, (2007) Read More / View Supplemental Materials
Abstract
Single nucleotide polymorphism array analysis of cancer.Dutt, A., and Beroukhim R. Current opinion in oncology, 2007/01/01, Volume 19, Issue 1, p.43-9, (2007) Read More / View Supplemental Materials
Abstract
Portraits of breast cancer progressionDalgin, Gul S., Alexe Gabriela, Scanfeld Daniel, Tamayo Pablo, Mesirov Jill P., Ganesan Shridar, DeLisi Charles, and Bhanot Gyan BMC Bioinformatics, 2007///, Volume 8, p.291 - 291, (2007) Read More / View Supplemental Materials
Abstract
Subclass mapping: identifying common subtypes in independent disease data setsHoshida, Yujin, Brunet Jean-Philippe, Tamayo Pablo, Golub Todd R., and Mesirov Jill P. PLoS ONE, 2007///, Volume 2, Issue 11, p.e1195 - e1195, (2007) Read More / View Supplemental Materials
Abstract
Ring-opening and ring-closing reactions of a shikimic acid-derived substrate leading to diverse small molecules.Miao, H., Tallarico JA, Hayakawa H., Münger K., Duffner JL, Koehler AN, Schreiber SL, and Lewis TA Journal of combinatorial chemistry, 1969/12/31, Volume 9, Issue 2, p.245-53, (2007) Read More / View Supplemental Materials
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2006
Schizophrenia: do the genetics and neurobiology of neuregulin provide a pathogenesis model?Scolnick, EM, Petryshen T., and Sklar P. Harvard review of psychiatry, 2006/12/31, Volume 14, Issue 2, p.64-77, (2006) Read More / View Supplemental Materials
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A method for the covalent capture and screening of diverse small molecules in a microarray format.Bradner, JE, McPherson OM, and Koehler AN Nature protocols, 2006/12/21, Volume 1, Issue 5, p.2344-52, (2006) Read More / View Supplemental Materials
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Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signalingKobayashi, Susumu, Shimamura Takeshi, Monti Stefano, Steidl Ulrich, Hetherington Christopher J., Lowell April M., Golub Todd, Meyerson Matthew, Tenen Daniel G., Shapiro Geoffrey I., and Halmos Bal Cancer Research, 2006/12/01/, Volume 66, Issue 23, p.11389 - 98, (2006) Read More / View Supplemental Materials
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Coevolution, modularity and human disease.Fraser, HB Current opinion in genetics & development, 2006/12/01, Volume 16, Issue 6, p.637-44, (2006) Read More / View Supplemental Materials
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Contributions of estrogen to ER-negative breast tumor growth.Gupta, PB, and Kuperwasser C. The Journal of steroid biochemistry and molecular biology, 2006/12/01, Volume 102, Issue 1-5, p.71-8, (2006) Read More / View Supplemental Materials
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Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.Lee, JC, Vivanco I., Beroukhim R., Huang JH, Feng WL, Debiasi RM, Yoshimoto K., King JC, Nghiemphu P., Yuza Y., Xu Q., Greulich H., Thomas RK, Paez JG, Peck TC, Linhart DJ, Glatt KA, Getz G., Onofrio R., Ziaugra L., et al. PLoS medicine, 2006/12/01, Volume 3, Issue 12, p.e485, (2006) Read More / View Supplemental Materials
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