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2008
Sequencing the nuclear genome of the extinct woolly mammoth.Miller, W., Drautz DI, Ratan A., Pusey B., Qi J., Lesk AM, Tomsho LP, Packard MD, Zhao F., Sher A., Tikhonov A., Raney B., Patterson N., Lindblad-Toh K., Lander E. S., Knight JR, Irzyk GP, Fredrikson KM, Harkins TT, Sheridan S., et al. Nature, 2008/11/20, Volume 456, Issue 7220, p.387-90, (2008) Read More / View Supplemental Materials
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CellProfiler Analyst: data exploration and analysis software for complex image-based screens.Jones, TR, Kang IH, Wheeler DB, Lindquist RA, Papallo A., Sabatini DM, Golland P., and Carpenter AE BMC bioinformatics, 2008/11/15, Volume 9, p.482, (2008) Read More / View Supplemental Materials
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Genetic mapping in human disease.Altshuler, D., Daly M. J., and Lander E. S. Science (New York, N.Y.), 2008/11/07, Volume 322, Issue 5903, p.881-8, (2008) Read More / View Supplemental Materials
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Gene expression in fixed tissues and outcome in hepatocellular carcinoma.Hoshida, Y., Villanueva A., Kobayashi M., Peix J., Chiang DY, Camargo A., Gupta S., Moore J., Wrobel MJ, Lerner J., Reich M., Chan JA, Glickman JN, Ikeda K., Hashimoto M., Watanabe G., Daidone MG, Roayaie S., Schwartz M., Thung S., et al. The New England journal of medicine, 2008/11/06, Volume 359, Issue 19, p.1995-2004, (2008) Read More / View Supplemental Materials
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Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines.Choy, E., Yelensky R., Bonakdar S., Plenge RM, Saxena R., De Jager PL, Shaw SY, Wolfish CS, Slavik JM, Cotsapas C., Rivas M., Dermitzakis ET, Cahir-McFarland E., Kieff E., Hafler D., Daly M. J., and Altshuler D. PLoS genetics, 2008/11/01, Volume 4, Issue 11, p.e1000287, (2008) Read More / View Supplemental Materials
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PCA and clustering reveal alternate mtDNA phylogeny of N and M clades.Alexe, G., Satya RV, Seiler M., Platt D., Bhanot T., Hui S., Tanaka M., Levine AJ, and Bhanot G. Journal of molecular evolution, 2008/11/01, Volume 67, Issue 5, p.465-87, (2008) Read More / View Supplemental Materials
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Protein quantitation through targeted mass spectrometry: the way out of biomarker purgatory?Carr, SA, and Anderson L. Clinical chemistry, 2008/11/01, Volume 54, Issue 11, p.1749-52, (2008) Read More / View Supplemental Materials
A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking.Daniels, R., Volkman SK, Milner DA, Mahesh N., Neafsey DE, Park DJ, Rosen D., Angelino E., Sabeti PC, Wirth DF, and Wiegand RC Malaria journal, 2008/10/29, Volume 7, p.223, (2008) Read More / View Supplemental Materials
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Somatic mutations affect key pathways in lung adenocarcinoma.Ding, L., Getz G., Wheeler DA, Mardis ER, McLellan MD, Cibulskis K., Sougnez C., Greulich H., Muzny DM, Morgan MB, Fulton L., Fulton RS, Zhang Q., Wendl MC, Lawrence MS, Larson DE, Chen K., Dooling DJ, Sabo A., Hawes AC, et al. Nature, 2008/10/23, Volume 455, Issue 7216, p.1069-75, (2008) Read More / View Supplemental Materials
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Activating mutations in ALK provide a therapeutic target in neuroblastoma.George, RE, Sanda T., Hanna M., Fröhling S., Luther W 2nd, Zhang J., Ahn Y., Zhou W., London WB, McGrady P., Xue L., Zozulya S., Gregor VE, Webb TR, Gray NS, Gilliland DG, Diller L., Greulich H., Morris SW, Meyerson M., et al. Nature, 2008/10/16, Volume 455, Issue 7215, p.975-8, (2008) Read More / View Supplemental Materials
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Autoimmune diseases: insights from genome-wide association studies.Lettre, G., and Rioux JD Human molecular genetics, 2008/10/15, Volume 17, Issue R2, p.R116-21, (2008) Read More / View Supplemental Materials
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Extending genome-wide association studies to copy-number variation.McCarroll, SA Human molecular genetics, 2008/10/15, Volume 17, Issue R2, p.R135-42, (2008) Read More / View Supplemental Materials
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Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.Li, Z., Lu J., Sun M., Mi S., Zhang H., Luo RT, Chen P., Wang Y., Yan M., Qian Z., Neilly MB, Jin J., Zhang Y., Bohlander SK, Zhang DE, Larson RA, Le Beau MM, Thirman MJ, Golub T. R., Rowley JD, et al. Proceedings of the National Academy of Sciences of the United States of America, 2008/10/07, Volume 105, Issue 40, p.15535-40, (2008) Read More / View Supplemental Materials
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Accurate inclusion mass screening: a bridge from unbiased discovery to targeted assay development for biomarker verification.Jaffe, JD, Keshishian H., Chang B., Addona TA, Gillette MA, and Carr SA Molecular & cellular proteomics : MCP, 2008/10/01, Volume 7, Issue 10, p.1952-62, (2008) Read More / View Supplemental Materials
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Common variants at CD40 and other loci confer risk of rheumatoid arthritis.Raychaudhuri, S., Remmers EF, Lee AT, Hackett R., Guiducci C., Burtt NP, Gianniny L., Korman BD, Padyukov L., Kurreeman FA, Chang M., Catanese JJ, Ding B., Wong S., van der Helm-van Mil AH, Neale BM, Coblyn J., Cui J., Tak PP, Wolbink GJ, et al. Nature genetics, 2008/10/01, Volume 40, Issue 10, p.1216-23, (2008) Read More / View Supplemental Materials
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Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains.Ku, M., Koche RP, Rheinbay E., Mendenhall EM, Endoh M., Mikkelsen TS, Presser A., Nusbaum C., Xie X., Chi AS, Adli M., Kasif S., Ptaszek LM, Cowan CA, Lander E. S., Koseki H., and Bernstein BE PLoS genetics, 2008/10/01, Volume 4, Issue 10, p.e1000242, (2008) Read More / View Supplemental Materials
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HapMap and mapping genes for cardiovascular disease.Musunuru, K., and Kathiresan S. Circulation. Cardiovascular genetics, 2008/10/01, Volume 1, Issue 1, p.66-71, (2008) Read More / View Supplemental Materials
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High-throughput screens for fluorescent dye discovery.Ljosa, V., and Carpenter AE Trends in biotechnology, 2008/10/01, Volume 26, Issue 10, p.527-30, (2008) Read More / View Supplemental Materials
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In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis.Caron, SJ, Prober D., Choy M., and Schier AF Development (Cambridge, England), 2008/10/01, Volume 135, Issue 19, p.3259-69, (2008) Read More / View Supplemental Materials
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Integrated detection and population-genetic analysis of SNPs and copy number variation.McCarroll, SA, Kuruvilla FG, Korn JM, Cawley S., Nemesh J., Wysoker A., Shapero MH, de Bakker PI, Maller JB, Kirby A., Elliott AL, Parkin M., Hubbell E., Webster T., Mei R., Veitch J., Collins PJ, Handsaker R., Lincoln S., Nizzari M., et al. Nature genetics, 2008/10/01, Volume 40, Issue 10, p.1166-74, (2008) Read More / View Supplemental Materials
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Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs.Korn, JM, Kuruvilla FG, McCarroll SA, Wysoker A., Nemesh J., Cawley S., Hubbell E., Veitch J., Collins PJ, Darvishi K., Lee C., Nizzari MM, Gabriel SB, Purcell S., Daly M. J., and Altshuler D. Nature genetics, 2008/10/01, Volume 40, Issue 10, p.1253-60, (2008) Read More / View Supplemental Materials
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Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury.Lewis, GD, Wei R., Liu E., Yang E., Shi X., Martinovic M., Farrell L., Asnani A., Cyrille M., Ramanathan A., Shaham O., Berriz G., Lowry PA, Palacios IF, Taşan M., Roth FP, Min J., Baumgartner C., Keshishian H., Addona T., et al. The Journal of clinical investigation, 2008/10/01, Volume 118, Issue 10, p.3503-12, (2008) Read More / View Supplemental Materials
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A common sequence motif associated with recombination hot spots and genome instability in humans.Myers, S., Freeman C., Auton A., Donnelly P., and McVean G. Nature genetics, 2008/09/01, Volume 40, Issue 9, p.1124-9, (2008) Read More / View Supplemental Materials
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Evolutionary toggling of the MAPT 17q21.31 inversion region.Zody, MC, Jiang Z., Fung HC, Antonacci F., Hillier LW, Cardone MF, Graves TA, Kidd JM, Cheng Z., Abouelleil A., Chen L., Wallis J., Glasscock J., Wilson RK, Reily AD, Duckworth J., Ventura M., Hardy J., Warren WC, and Eichler EE Nature genetics, 2008/09/01, Volume 40, Issue 9, p.1076-83, (2008) Read More / View Supplemental Materials
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Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.Graham, RR, Cotsapas C., Davies L., Hackett R., Lessard CJ, Leon JM, Burtt NP, Guiducci C., Parkin M., Gates C., Plenge RM, Behrens TW, Wither JE, Rioux JD, Fortin PR, Graham DC, Wong AK, Vyse TJ, Daly M. J., Altshuler D., et al. Nature genetics, 2008/09/01, Volume 40, Issue 9, p.1059-61, (2008) Read More / View Supplemental Materials
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Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells.Tam, WF, Gu TL, Chen J., Lee BH, Bullinger L., Fröhling S., Wang A., Monti S., Golub T. R., and Gilliland DG Blood, 2008/09/01, Volume 112, Issue 5, p.1981-92, (2008) Read More / View Supplemental Materials
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Leader of the pack: gene mapping in dogs and other model organisms.Karlsson, EK, and Lindblad-Toh K. Nature reviews. Genetics, 2008/09/01, Volume 9, Issue 9, p.713-25, (2008) Read More / View Supplemental Materials
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Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor.Bowers, A., West N., Taunton J., Schreiber SL, Bradner JE, and Williams RM Journal of the American Chemical Society, 2008/08/20, Volume 130, Issue 33, p.11219-22, (2008) Read More / View Supplemental Materials
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DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease.Lettre, G., Sankaran VG, Bezerra MA, Araújo AS, Uda M., Sanna S., Cao A., Schlessinger D., Costa FF, Hirschhorn JN, and Orkin SH Proceedings of the National Academy of Sciences of the United States of America, 2008/08/19, Volume 105, Issue 33, p.11869-74, (2008) Read More / View Supplemental Materials
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Genome-scale DNA methylation maps of pluripotent and differentiated cells.Meissner, A., Mikkelsen TS, Gu H., Wernig M., Hanna J., Sivachenko A., Zhang X., Bernstein BE, Nusbaum C., Jaffe DB, Gnirke A., Jaenisch R., and Lander E. S. Nature, 2008/08/07, Volume 454, Issue 7205, p.766-70, (2008) Read More / View Supplemental Materials
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Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells.Haining, WN, Ebert BL, Subrmanian A., Wherry EJ, Eichbaum Q., Evans JW, Mak R., Rivoli S., Pretz J., Angelosanto J., Smutko JS, Walker BD, Kaech SM, Ahmed R., Nadler LM, and Golub T. R. Journal of immunology (Baltimore, Md. : 1950), 2008/08/01, Volume 181, Issue 3, p.1859-68, (2008) Read More / View Supplemental Materials
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A set of reference sequences for the hepatitis C genotypes 4d, 4f, and 4k covering the full open reading frame.Kuntzen, T., Berical A., Ndjomou J., Bennett P., Schneidewind A., Lennon N., Birren BW, Kuiken C., Henn MR, Simmonds P., and Allen TM Journal of medical virology, 2008/08/01, Volume 80, Issue 8, p.1370-8, (2008) Read More / View Supplemental Materials
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Conserved secondary structures in Aspergillus.McGuire, AM, and Galagan JE PloS one, 2008/07/30, Volume 3, Issue 7, p.e2812, (2008) Read More / View Supplemental Materials
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Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiationHahn, Cynthia K., Ross Kenneth N., Warrington Ian M., Mazitschek Ralph, Kanegai Cindy M., Wright Renee D., Kung Andrew L., Golub Todd R., and Stegmaier Kimberly Proceedings of the National Academy of Sciences of the United States of America, 2008/07/15/, Volume 105, Issue 28, p.9751 - 6, (2008) Read More / View Supplemental Materials
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Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation.Hahn, CK, Ross KN, Warrington IM, Mazitschek R., Kanegai CM, Wright RD, Kung AL, Golub T. R., and Stegmaier K. Proceedings of the National Academy of Sciences of the United States of America, 2008/07/15, Volume 105, Issue 28, p.9751-6, (2008) Read More / View Supplemental Materials
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A mitochondrial protein compendium elucidates complex I disease biologyPagliarini, David J., Calvo Sarah E., Chang Betty, Sheth Sunil A., Vafai Scott B., Ong Shao-En, Walford Geoffrey A., Sugiana Canny, Boneh Avihu, Chen William K., Hill David E., Vidal Marc, Evans James G., Thorburn David R., Carr Steven A., and Mootha Vamsi K. Cell, 2008/07/11/, Volume 134, Issue 1, p.112 - 23, (2008) Read More / View Supplemental Materials
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A mitochondrial protein compendium elucidates complex I disease biology.Pagliarini, DJ, Calvo SE, Chang B., Sheth SA, Vafai SB, Ong SE, Walford GA, Sugiana C., Boneh A., Chen WK, Hill DE, Vidal M., Evans JG, Thorburn DR, Carr SA, and Mootha VK Cell, 2008/07/11, Volume 134, Issue 1, p.112-23, (2008) Read More / View Supplemental Materials
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Dissecting direct reprogramming through integrative genomic analysis.Mikkelsen, TS, Hanna J., Zhang X., Ku M., Wernig M., Schorderet P., Bernstein BE, Jaenisch R., Lander E. S., and Meissner A. Nature, 2008/07/03, Volume 454, Issue 7200, p.49-55, (2008) Read More / View Supplemental Materials
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Diversity synthesis of complex pyridines yields a probe of a neurotrophic signaling pathway.Gray, BL, Wang X., Brown WC, Kuai L., and Schreiber SL Organic letters, 2008/07/03, Volume 10, Issue 13, p.2621-4, (2008) Read More / View Supplemental Materials
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15-Hydroxyprostaglandin dehydrogenase is a target of hepatocyte nuclear factor 3beta and a tumor suppressor in lung cancerHuang, Guosheng, Eisenberg Rosana, Yan Min, Monti Stefano, Lawrence Earl, Fu Pingfu, Walbroehl Jaclyn, and L Cancer Research, 2008/07/01/, Volume 68, Issue 13, p.5040 - 8, (2008) Read More / View Supplemental Materials
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Increasing ecological inference from high throughput sequencing of fungi in the environment through a tagging approach.Taylor, DL, Booth MG, McFarland JW, Herriott IC, Lennon NJ, Nusbaum C., and Marr TG Molecular ecology resources, 2008/07/01, Volume 8, Issue 4, p.742-52, (2008) Read More / View Supplemental Materials
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Small-molecule microarrays as tools in ligand discovery.Vegas, AJ, Fuller JH, and Koehler AN Chemical Society reviews, 2008/07/01, Volume 37, Issue 7, p.1385-94, (2008) Read More / View Supplemental Materials
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Drug-sensitive FGFR2 mutations in endometrial carcinoma.Dutt, A., Salvesen HB, Chen TH, Ramos AH, Onofrio RC, Hatton C., Nicoletti R., Winckler W., Grewal R., Hanna M., Wyhs N., Ziaugra L., Richter DJ, Trovik J., Engelsen IB, Stefansson IM, Fennell T., Cibulskis K., Zody MC, Akslen LA, et al. Proceedings of the National Academy of Sciences of the United States of America, 2008/06/24, Volume 105, Issue 25, p.8713-7, (2008) Read More / View Supplemental Materials
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Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancerSetlur, Sunita R., Mertz Kirsten D., Hoshida Yujin, Demichelis Francesca, Lupien Mathieu, Perner Sven, Sboner Andrea, Pawitan Yudi, and Andr Journal of the National Cancer Institute, 2008/06/04/, Volume 100, Issue 11, p.815 - 25, (2008) Read More / View Supplemental Materials
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Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer.Setlur, SR, Mertz KD, Hoshida Y., Demichelis F., Lupien M., Perner S., Sboner A., Pawitan Y., Andrén O., Johnson LA, Tang J., Adami HO, Calza S., Chinnaiyan AM, Rhodes D., Tomlins S., Fall K., Mucci LA, Kantoff PW, Stampfer MJ, et al. Journal of the National Cancer Institute, 2008/06/04, Volume 100, Issue 11, p.815-25, (2008) Read More / View Supplemental Materials
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The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.Lee, KB, De Backer P., Aono T., Liu CT, Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer DM, Najar FZ, Wiley GB, Roe B., Binnewies TT, Ussery DW, D'Haeze W., Herder JD, Gevers D., Vereecke D., Holsters M., et al. BMC genomics, 2008/06/04, Volume 9, p.271, (2008) Read More / View Supplemental Materials
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Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cellsMishra, Pravin J., Mishra Prasun J., Humeniuk Rita, Medina Daniel J., Alexe Gabriela, Mesirov Jill P., Ganesan Sridhar, Glod John W., and Banerjee Debabrata Cancer Research, 2008/06/01/, Volume 68, Issue 11, p.4331 - 9, (2008) Read More / View Supplemental Materials
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MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors.Lu, J., Guo S., Ebert BL, Zhang H., Peng X., Bosco J., Pretz J., Schlanger R., Wang JY, Mak RH, Dombkowski DM, Preffer FI, Scadden DT, and Golub T. R. Developmental cell, 2008/06/01, Volume 14, Issue 6, p.843-53, (2008) Read More / View Supplemental Materials
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Targeted mutagenesis in zebrafish.Woods, IG, and Schier AF Nature biotechnology, 2008/06/01, Volume 26, Issue 6, p.650-1, (2008) Read More / View Supplemental Materials
Transcriptome and metabolite responses to predation in a South pacific soft coral.Hoover, CA, Slattery M., Targett NM, and Marsh AG The Biological bulletin, 2008/06/01, Volume 214, Issue 3, p.319-28, (2008) Read More / View Supplemental Materials
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Using ChemBank to probe chemical biology.Petri Seiler, K., Kuehn H., Pat Happ M., DeCaprio D., and Clemons PA Current protocols in bioinformatics / editoral board, Andreas D. Baxevanis ... [et al.], 2008/06/01, Volume Chapter 14, p.Unit 14.5, (2008) Read More / View Supplemental Materials
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Using GenePattern for gene expression analysis.Kuehn, H., Liberzon A., Reich M., and Mesirov J. P. Current protocols in bioinformatics / editoral board, Andreas D. Baxevanis ... [et al.], 2008/06/01, Volume Chapter 7, p.Unit 7.12, (2008) Read More / View Supplemental Materials
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MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitorsLu, Jun, Guo Shangqin, Ebert Benjamin L., Zhang Hao, Peng Xiao, Bosco Jocelyn, Pretz Jennifer, Schlanger Rita, Wang Judy Y., Mak Raymond H., Dombkowski David M., Preffer Frederic I., Scadden David T., and Golub Todd R. Developmental Cell, 2008/06//, Volume 14, Issue 6, p.843 - 53, (2008) Read More / View Supplemental Materials
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Perturbational profiling of nanomaterial biologic activity.Shaw, SY, Westly EC, Pittet MJ, Subramanian A., Schreiber SL, and Weissleder R. Proceedings of the National Academy of Sciences of the United States of America, 2008/05/27, Volume 105, Issue 21, p.7387-92, (2008) Read More / View Supplemental Materials
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Resource partitioning and sympatric differentiation among closely related bacterioplankton.Hunt, DE, David LA, Gevers D., Preheim SP, Alm EJ, and Polz MF Science (New York, N.Y.), 2008/05/23, Volume 320, Issue 5879, p.1081-5, (2008) Read More / View Supplemental Materials
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Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways.Onder, TT, Gupta PB, Mani SA, Yang J., Lander E. S., and Weinberg R. A. Cancer research, 2008/05/15, Volume 68, Issue 10, p.3645-54, (2008) Read More / View Supplemental Materials
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ALLPATHS: de novo assembly of whole-genome shotgun microreads.Butler, J., Maccallum I., Kleber M., Shlyakhter IA, Belmonte MK, Lander E. S., Nusbaum C., and Jaffe DB Genome research, 2008/05/01, Volume 18, Issue 5, p.810-20, (2008) Read More / View Supplemental Materials
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Can one learn history from the allelic spectrum?Myers, S., Fefferman C., and Patterson N. Theoretical population biology, 2008/05/01, Volume 73, Issue 3, p.342-8, (2008) Read More / View Supplemental Materials
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Development of a fluorescence polarization based assay for histone deacetylase ligand discovery.Mazitschek, R., Patel V., Wirth DF, and Clardy J. Bioorganic & medicinal chemistry letters, 2008/05/01, Volume 18, Issue 9, p.2809-12, (2008) Read More / View Supplemental Materials
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Identification of ten loci associated with height highlights new biological pathways in human growth.Lettre, G., Jackson AU, Gieger C., Schumacher FR, Berndt SI, Sanna S., Eyheramendy S., Voight BF, Butler JL, Guiducci C., Illig T., Hackett R., Heid IM, Jacobs KB, Lyssenko V., Uda M., Diabetes Genetics Initiative, FUSION, KORA, Prostate, Lung Colorectal and Ovarian Cancer Screening Trial, et al. Nature genetics, 2008/05/01, Volume 40, Issue 5, p.584-91, (2008) Read More / View Supplemental Materials
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Mapping and sequencing of structural variation from eight human genomes.Kidd, JM, Cooper GM, Donahue WF, Hayden HS, Sampas N., Graves T., Hansen N., Teague B., Alkan C., Antonacci F., Haugen E., Zerr T., Yamada NA, Tsang P., Newman TL, Tüzün E., Cheng Z., Ebling HM, Tusneem N., David R., et al. Nature, 2008/05/01, Volume 453, Issue 7191, p.56-64, (2008) Read More / View Supplemental Materials
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Quality scores and SNP detection in sequencing-by-synthesis systems.Brockman, W., Alvarez P., Young S., Garber M., Giannoukos G., Lee WL, Russ C., Lander E. S., Nusbaum C., and Jaffe DB Genome research, 2008/05/01, Volume 18, Issue 5, p.763-70, (2008) Read More / View Supplemental Materials
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Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): I. CIP Treatment of Samples and Tailing Reaction with Terminal Transferase.Liu, CL, Bernstein BE, and Schreiber SL CSH protocols, 2008/05/01, Volume 2008, p.pdb.prot5002, (2008) Read More / View Supplemental Materials
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Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): II. Second-Strand Synthesis and In Vitro Transcription.Liu, CL, Bernstein BE, and Schreiber SL CSH protocols, 2008/05/01, Volume 2008, p.pdb.prot5003, (2008) Read More / View Supplemental Materials
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Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): III. Sample Purification.Liu, CL, Bernstein BE, and Schreiber SL CSH protocols, 2008/05/01, Volume 2008, p.pdb.prot5004, (2008) Read More / View Supplemental Materials
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Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): Overview.Liu, CL, Bernstein BE, and Schreiber SL CSH protocols, 2008/05/01, Volume 2008, p.pdb.top42, (2008) Read More / View Supplemental Materials
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Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastasesXu, Lei, Shen Steven S., Hoshida Yujin, Subramanian Aravind, Ross Ken, Brunet Jean-Philippe, Wagner Stephan N., Ramaswamy Sridhar, Mesirov Jill P., and Hynes Richard O. Molecular Cancer Research: MCR, 2008/05//, Volume 6, Issue 5, p.760 - 9, (2008) Read More / View Supplemental Materials
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Performance and scalability of discriminative metrics for comparative gene identification in 12 Drosophila genomes.Lin, MF, Deoras AN, Rasmussen MD, and Kellis M. PLoS computational biology, 2008/04/18, Volume 4, Issue 4, p.e1000067, (2008) Read More / View Supplemental Materials
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Zinc-catalyzed silylation of terminal alkynes.Rahaim RJ, Jr, and Shaw JT The Journal of organic chemistry, 2008/04/04, Volume 73, Issue 7, p.2912-5, (2008) Read More / View Supplemental Materials
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Small-molecule fluorophores to detect cell-state switching in the context of high-throughput screening.Wagner, BK, Carrinski HA, Ahn YH, Kim YK, Gilbert TJ, Fomina DA, Schreiber SL, Chang YT, and Clemons PA Journal of the American Chemical Society, 2008/04/02, Volume 130, Issue 13, p.4208-9, (2008) Read More / View Supplemental Materials
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Using CellProfiler for automatic identification and measurement of biological objects in images.Vokes, MS, and Carpenter AE Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.], 2008/04/01, Volume Chapter 14, p.Unit 14.17, (2008) Read More / View Supplemental Materials
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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.Christofk, HR, Vander Heiden MG, Harris MH, Ramanathan A., Gerszten RE, Wei R., Fleming MD, Schreiber SL, and Cantley LC Nature, 2008/03/13, Volume 452, Issue 7184, p.230-3, (2008) Read More / View Supplemental Materials
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Large-scale chemical dissection of mitochondrial function.Wagner, BK, Kitami T., Gilbert TJ, Peck D., Ramanathan A., Schreiber SL, Golub T. R., and Mootha VK Nature biotechnology, 2008/03/01, Volume 26, Issue 3, p.343-51, (2008) Read More / View Supplemental Materials
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Small-molecule reagents for cellular pull-down experiments.Wang, X., Imber BS, and Schreiber SL Bioconjugate chemistry, 2008/03/01, Volume 19, Issue 3, p.585-7, (2008) Read More / View Supplemental Materials
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SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphomaChen, Linfeng, Monti Stefano, Juszczynski Przemyslaw, Daley John, Chen Wen, Witzig Thomas E., Habermann Thomas M., Kutok Jeffery L., and Shipp Margaret A. Blood, 2008/02/15/, Volume 111, Issue 4, p.2230 - 7, (2008) Read More / View Supplemental Materials
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Complex selection on intron size in Cryptococcus neoformans.Hughes, SS, Buckley CO, and Neafsey DE Molecular biology and evolution, 2008/02/01, Volume 25, Issue 2, p.247-53, (2008) Read More / View Supplemental Materials
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An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndrome.Ebert, BL, Galili N., Tamayo P., Bosco J., Mak R., Pretz J., Tanguturi S., Ladd-Acosta C., Stone R., Golub T. R., and Raza A. PLoS medicine, 2008/02/01, Volume 5, Issue 2, p.e35, (2008) Read More / View Supplemental Materials
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Modeling genomic diversity and tumor dependency in malignant melanoma.Lin, WM, Baker AC, Beroukhim R., Winckler W., Feng W., Marmion JM, Laine E., Greulich H., Tseng H., Gates C., Hodi FS, Dranoff G., Sellers WR, Thomas RK, Meyerson M., Golub T. R., Dummer R., Herlyn M., Getz G., and Garraway LA Cancer research, 2008/02/01, Volume 68, Issue 3, p.664-73, (2008) Read More / View Supplemental Materials
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An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndromeEbert, Benjamin L., Galili Naomi, Tamayo Pablo, Bosco Jocelyn, Mak Raymond, Pretz Jennifer, Tanguturi Shyam, Ladd-Acosta Christine, Stone Richard, Golub Todd R., and Raza Azra PLoS Medicine, 2008/02//, Volume 5, Issue 2, p.e35 - e35, (2008) Read More / View Supplemental Materials
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An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndromeEbert, Benjamin L., Galili Naomi, Tamayo Pablo, Bosco Jocelyn, Mak Raymond, Pretz Jennifer, Tanguturi Shyam, Ladd-Acosta Christine, Stone Richard, Golub Todd R., and Raza Azra PLoS Medicine, 2008/02//, Volume 5, Issue 2, p.e35 - e35, (2008) Read More / View Supplemental Materials
Abstract
Cancer: hay in a haystackShannon, Kevin M., and Le Beau Michelle M. Nature, 2008/01/17/, Volume 451, Issue 7176, p.252 - 3, (2008) Read More / View Supplemental Materials
Identification of RPS14 as a 5q- syndrome gene by RNA interference screenEbert, Benjamin L., Pretz Jennifer, Bosco Jocelyn, Chang Cindy Y., Tamayo Pablo, Galili Naomi, Raza Azra, Root David E., Attar Eyal, Ellis Steven R., and Golub Todd R. Nature, 2008/01/17/, Volume 451, Issue 7176, p.335 - 9, (2008) Read More / View Supplemental Materials
Abstract
Identification of RPS14 as a 5q- syndrome gene by RNA interference screen.Ebert, BL, Pretz J., Bosco J., Chang CY, Tamayo P., Galili N., Raza A., Root DE, Attar E., Ellis SR, and Golub T. R. Nature, 2008/01/17, Volume 451, Issue 7176, p.335-9, (2008) Read More / View Supplemental Materials
Abstract
Integrative analysis reveals 53BP1 copy loss and decreased expression in a subset of human diffuse large B-cell lymphomasTakeyama, K., Monti S., Manis J. P., Cin Dal P., Getz G., Beroukhim R., Dutt S., Aster J. C., Alt F. W., Golub T. R., and Shipp M. A. Oncogene, 2008/01/10/, Volume 27, Issue 3, p.318 - 22, (2008) Read More / View Supplemental Materials
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Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity.Nieland, TJ, Shaw JT, Jaipuri FA, Duffner JL, Koehler AN, Banakos S., Zannis VI, Kirchhausen T., and Krieger M. Biochemistry, 2008/01/08, Volume 47, Issue 1, p.460-72, (2008) Read More / View Supplemental Materials
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Analysis of alternative splicing in plants with bioinformatics tools.Haas, BJ Current topics in microbiology and immunology, 2008/01/01, Volume 326, p.17-37, (2008) Read More / View Supplemental Materials
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ChemBank: a small-molecule screening and cheminformatics resource database.Seiler, KP, George GA, Happ MP, Bodycombe NE, Carrinski HA, Norton S., Brudz S., Sullivan JP, Muhlich J., Serrano M., Ferraiolo P., Tolliday NJ, Schreiber SL, and Clemons PA Nucleic acids research, 2008/01/01, Volume 36, Issue Database issue, p.D351-9, (2008) Read More / View Supplemental Materials
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Conservation of the chitin utilization pathway in the Vibrionaceae.Hunt, DE, Gevers D., Vahora NM, and Polz MF Applied and environmental microbiology, 2008/01/01, Volume 74, Issue 1, p.44-51, (2008) Read More / View Supplemental Materials
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Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity.Shaham, O., Wei R., Wang TJ, Ricciardi C., Lewis GD, Vasan RS, Carr SA, Thadhani R., Gerszten RE, and Mootha VK Molecular systems biology, 2008/01/01, Volume 4, p.214, (2008) Read More / View Supplemental Materials
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Probing the cancer genome.Greulich, H. Genome biology, 2008/01/01, Volume 9, Issue 5, p.309, (2008) Read More / View Supplemental Materials
A single Hox locus in Drosophila produces functional microRNAs from opposite DNA strands.Stark, A., Bushati N., Jan CH, Kheradpour P., Hodges E., Brennecke J., Bartel DP, Cohen SM, and Kellis M. Genes & development, 2008/01/01, Volume 22, Issue 1, p.8-13, (2008) Read More / View Supplemental Materials
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Towards the optimal screening collection: a synthesis strategy.Nielsen, TE, and Schreiber SL Angewandte Chemie (International ed. in English), 2007/12/13, Volume 47, Issue 1, p.48-56, (2008) Read More / View Supplemental Materials
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Boosting permutation tests for marker selectionGad Getz, Joshua Gold, Stefano Monti, (2008) Read More / View Supplemental Materials
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An erythroid differentiation signature predicts response to lenalidomide in Myelodysplastic SyndromeBenjamin L. Ebert, Naomi Galili, Pablo Tamayo Jocelyn Bosco Raymond Mak Jennifer Pretz Christine Ladd-Acosta Richard Stone, and Raza Azra, Volume 5, Issue 2, p.e35, (2008) Read More / View Supplemental Materials
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Gene Expression Changes in an Animal Melanoma Model Correlate with Aggressiveness of Human Melanoma MetastasesLei Xu, Steven S. Shen, Yujin Hoshida Aravind Subramanian Ken Ross Jean-Philippe Brunet Stephan Wagner Sridhar Ramaswamy N., and Hynes Richard O., Volume 6, Issue May 1, p.760-769, (2008) Read More / View Supplemental Materials
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High-resolution mapping of copy-number alterations with massively parallel sequencingDerek Y. Chiang, Gad Getz, David Jaffe Xiaojun Zhao Scott Carter Carsten Russ Chad Nusbaum Matthew Meyerson Eric B. L., (2008) Read More / View Supplemental Materials
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2007
Assessing the significance of chromosomal aberrations in cancer: methodology and application to gliomaBeroukhim, Rameen, Getz Gad, Nghiemphu Leia, Barretina Jordi, Hsueh Teli, Linhart David, Vivanco Igor, Lee Jeffrey C., Huang Julie H., Alexander Sethu, Du Jinyan, Kau Tweeny, Thomas Roman K., Shah Kinjal, Soto Horacio, Perner Sven, Prensner John, and Debiasi Ralp Proceedings of the National Academy of Sciences of the United States of America, 2007/12/11/, Volume 104, Issue 50, p.20007 - 12, (2007) Read More / View Supplemental Materials
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Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma.Beroukhim, R., Getz G., Nghiemphu L., Barretina J., Hsueh T., Linhart D., Vivanco I., Lee JC, Huang JH, Alexander S., Du J., Kau T., Thomas RK, Shah K., Soto H., Perner S., Prensner J., Debiasi RM, Demichelis F., Hatton C., et al. Proceedings of the National Academy of Sciences of the United States of America, 2007/12/11, Volume 104, Issue 50, p.20007-12, (2007) Read More / View Supplemental Materials
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MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia.Mi, S., Lu J., Sun M., Li Z., Zhang H., Neilly MB, Wang Y., Qian Z., Jin J., Zhang Y., Bohlander SK, Le Beau MM, Larson RA, Golub T. R., Rowley JD, and Chen J. Proceedings of the National Academy of Sciences of the United States of America, 2007/12/11, Volume 104, Issue 50, p.19971-6, (2007) Read More / View Supplemental Materials
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Characterizing the cancer genome in lung adenocarcinomaWeir, Barbara A., Woo Michele S., Getz Gad, Perner Sven, Ding Li, Beroukhim Rameen, Lin William M., Province Michael A., Kraja Aldi, Johnson Laura A., Shah Kinjal, Sato Mitsuo, Thomas Roman K., Barletta Justine A., Borecki Ingrid B., Broderick Stephen, and Chang Andre Nature, 2007/12/06/, Volume 450, Issue 7171, p.893 - 8, (2007) Read More / View Supplemental Materials
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