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2012
Concordance and Discordance in Tumor Genomic Profiling.Garraway, LA Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012/07/23, (2012) Read More / View Supplemental Materials
A landscape of driver mutations in melanoma.Hodis, E., Watson IR, Kryukov GV, Arold ST, Imielinski M., Theurillat JP, Nickerson E., Auclair D., Li L., Place C., Dicara D., Ramos AH, Lawrence MS, Cibulskis K., Sivachenko A., Voet D., Saksena G., Stransky N., Onofrio RC, Winckler W., et al. Cell, 2012/07/20, Volume 150, Issue 2, p.251-63, (2012) Read More / View Supplemental Materials
Abstract
Microsporidian genome analysis reveals evolutionary strategies for obligate intracellular growth.Cuomo, CA, Desjardins CA, Bakowski MA, Goldberg J., Ma AT, Becnel JJ, Didier ES, Fan L., Heiman DI, Levin JZ, Young S., Zeng Q., and Troemel ER Genome research, 2012/07/18, (2012) Read More / View Supplemental Materials
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Paired-end sequencing of Fosmid libraries by Illumina.Williams, LJ, Tabbaa DG, Li N., Berlin AM, Shea TP, Maccallum I., Lawrence MS, Drier Y., Getz G., Young SK, Jaffe DB, Nusbaum C., and Gnirke A. Genome research, 2012/07/17, (2012) Read More / View Supplemental Materials
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A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers.Lee, RS, Stewart C., Carter SL, Ambrogio L., Cibulskis K., Sougnez C., Lawrence MS, Auclair D., Mora J., Golub T. R., Biegel JA, Getz G., and Roberts CW The Journal of clinical investigation, 2012/07/16, (2012) Read More / View Supplemental Materials
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Wisdom of crowds for robust gene network inference.Marbach, D., Costello JC, Küffner R., Vega NM, Prill RJ, Camacho DM, Allison KR, The DREAM5 Consortium, Aderhold A., Allison KR, Bonneau R., Camacho DM, Chen Y., Collins JJ, Cordero F., Costello JC, Crane M., Dondelinger F., Drton M., Esposito R., et al. Nature methods, 2012/07/15, (2012) Read More / View Supplemental Materials
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Reconstructing Native American population history.Reich, D., Patterson N., Campbell D., Tandon A., Mazieres S., Ray N., Parra MV, Rojas W., Duque C., Mesa N., García LF, Triana O., Blair S., Maestre A., Dib JC, Bravi CM, Bailliet G., Corach D., Hünemeier T., Bortolini MC, et al. Nature, 2012/07/11, (2012) Read More / View Supplemental Materials
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Untuning the tumor metabolic machine: Targeting cancer metabolism: a bedside lesson.Birsoy, K., Sabatini DM, and Possemato R. Nature medicine, 2012/07/06, Volume 18, Issue 7, p.1022-3, (2012) Read More / View Supplemental Materials
Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity.Fass, DM, Reis SA, Ghosh B., Hennig KM, Joseph NF, Zhao WN, Nieland TJ, Guan JS, Groves Kuhnle CE, Tang W., Barker DD, Mazitschek R., Schreiber SL, Tsai LH, and Haggarty SJ Neuropharmacology, 2012/07/04, (2012) Read More / View Supplemental Materials
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Strain-Specific Regulation of Striatal Phenotype in Drd2-eGFP BAC Transgenic Mice.Chan, CS, Peterson JD, Gertler TS, Glajch KE, Quintana RE, Cui Q., Sebel LE, Plotkin JL, Shen W., Heiman M., Heintz N., Greengard P., and Surmeier DJ The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012/07/04, Volume 32, Issue 27, p.9124-9132, (2012) Read More / View Supplemental Materials
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Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion.Straussman, R., Morikawa T., Shee K., Barzily-Rokni M., Qian ZR, Du J., Davis A., Mongare MM, Gould J., Frederick DT, Cooper ZA, Chapman PB, Solit DB, Ribas A., Lo RS, Flaherty KT, Ogino S., Wargo JA, and Golub T. R. Nature, 2012/07/04, (2012) Read More / View Supplemental Materials
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Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia.Sankaran, VG, Ghazvinian R., Do R., Thiru P., Vergilio JA, Beggs AH, Sieff CA, Orkin SH, Nathan DG, Lander E. S., and Gazda HT The Journal of clinical investigation, 2012/07/02, Volume 122, Issue 7, p.2439-43, (2012) Read More / View Supplemental Materials
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Efficiency and power as a function of sequence coverage, SNP array density, and imputation.Flannick, J., Korn JM, Fontanillas P., Grant GB, Banks E., DePristo MA, and Altshuler D. PLoS computational biology, 2012/07/01, Volume 8, Issue 7, p.e1002604, (2012) Read More / View Supplemental Materials
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Structural haplotypes and recent evolution of the human 17q21.31 region.Boettger, LM, Handsaker RE, Zody MC, and McCarroll SA Nature genetics, 2012/07/01, (2012) Read More / View Supplemental Materials
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The uncertain road towards genomic medicine.Macarthur, DG, and Lek M. Trends in genetics : TIG, 2012/07/01, Volume 28, Issue 7, p.303-5, (2012) Read More / View Supplemental Materials
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Annotated high-throughput microscopy image sets for validation.Ljosa, V., Sokolnicki KL, and Carpenter AE Nature methods, 2012/06/28, Volume 9, Issue 7, p.637, (2012) Read More / View Supplemental Materials
A call for bioimaging software usability.Carpenter, AE, Kamentsky L., and Eliceiri KW Nature methods, 2012/06/28, Volume 9, Issue 7, p.666-70, (2012) Read More / View Supplemental Materials
Amino acids and mTORC1: from lysosomes to disease.Efeyan, A., Zoncu R., and Sabatini DM Trends in molecular medicine, 2012/06/27, (2012) Read More / View Supplemental Materials
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Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers.Briggs, AW, Rios X., Chari R., Yang L., Zhang F., Mali P., and Church GM Nucleic acids research, 2012/06/26, (2012) Read More / View Supplemental Materials
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Genomic sequencing of Plasmodium falciparum malaria parasites from Senegal reveals the demographic history of the population.Chang, HH, Park DJ, Galinsky KJ, Schaffner SF, Ndiaye D., Ndir O., Mboup S., Wiegand RC, Volkman SK, Sabeti PC, Wirth DF, Neafsey DE, and Hartl DL Molecular biology and evolution, 2012/06/24, (2012) Read More / View Supplemental Materials
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Inhibition of histone deacetylase 3 protects Beta cells from cytokine-induced apoptosis.Chou, DH, Holson EB, Wagner FF, Tang AJ, Maglathlin RL, Lewis TA, Schreiber SL, and Wagner BK Chemistry & biology, 2012/06/22, Volume 19, Issue 6, p.669-73, (2012) Read More / View Supplemental Materials
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Sequence analysis of mutations and translocations across breast cancer subtypes.Banerji, S., Cibulskis K., Rangel-Escareno C., Brown KK, Carter SL, Frederick AM, Lawrence MS, Sivachenko AY, Sougnez C., Zou L., Cortes ML, Fernandez-Lopez JC, Peng S., Ardlie KG, Auclair D., Bautista-Piña V., Duke F., Francis J., Jung J., Maffuz-Aziz A., et al. Nature, 2012/06/20, Volume 486, Issue 7403, p.405-9, (2012) Read More / View Supplemental Materials
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Activity-dependent A-to-I RNA Editing in Rat Cortical Neurons.Sanjana, NE, Levanon EY, Hueske EA, Ambrose JM, and Li JB Genetics, 2012/06/19, (2012) Read More / View Supplemental Materials
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Efficient algorithms for the reconciliation problem with gene duplication, horizontal transfer and loss.Bansal, MS, Alm EJ, and Kellis M. Bioinformatics (Oxford, England), 2012/06/15, Volume 28, Issue 12, p.i283-i291, (2012) Read More / View Supplemental Materials
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The promise and perils of stem cell therapeutics.Daley, GQ Cell stem cell, 2012/06/14, Volume 10, Issue 6, p.740-9, (2012) Read More / View Supplemental Materials
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Integrative Genomic Analysis Implicates Gain of PIK3CA at 3q26 and MYC at 8q24 in Chronic Lymphocytic Leukemia.Brown, JR, Hanna M., Tesar B., Werner L., Pochet N., Asara JM, Wang YE, Dal Cin P., Fernandes SM, Thompson C., MacConaill L., Wu CJ, Van de Peer Y., Correll M., Regev A., Neuberg D., and Freedman AS Clinical cancer research : an official journal of the American Association for Cancer Research, 2012/06/13, (2012) Read More / View Supplemental Materials
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Genetic polymorphisms for estimating risk of atrial fibrillation: a literature-based meta-analysis.Gustav Smith, J., Almgren P., Engström G., Hedblad B., Platonov PG, Newton-Cheh C., and Melander O. Journal of internal medicine, 2012/06/12, (2012) Read More / View Supplemental Materials
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Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.Bergen, SE, O'Dushlaine CT, Ripke S., Lee PH, Ruderfer DM, Akterin S., Moran JL, Chambert KD, Handsaker RE, Backlund L., Osby U., McCarroll S., Landen M., Scolnick EM, Magnusson PK, Lichtenstein P., Hultman CM, Purcell SM, Sklar P., and Sullivan PF Molecular psychiatry, 2012/06/12, (2012) Read More / View Supplemental Materials
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Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs.Cade, L., Reyon D., Hwang WY, Tsai SQ, Patel S., Khayter C., Joung JK, Sander JD, Peterson RT, and Yeh JR Nucleic acids research, 2012/06/07, (2012) Read More / View Supplemental Materials
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The Role of Genetic Markers in the Management of Prostate Cancer.Choudhury, AD, Eeles R., Freedland SJ, Isaacs WB, Pomerantz MM, Schalken JA, Tammela TL, and Visakorpi T. European urology, 2012/06/05, (2012) Read More / View Supplemental Materials
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Attenuation of notch and hedgehog signaling is required for fate specification in the spinal cord.Huang, P., Xiong F., Megason SG, and Schier AF PLoS genetics, 2012/06/01, Volume 8, Issue 6, p.e1002762, (2012) Read More / View Supplemental Materials
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Dosage and tumour suppression.Berger, AH, Knudson AG, and Pandolfi PP The Journal of pathology, 2012/06/01, Volume 227, Issue 2, p.e1, (2012) Read More / View Supplemental Materials
Identifying gnostic predictors of the vaccine response.Haining, WN, and Pulendran B. Current opinion in immunology, 2012/06/01, Volume 24, Issue 3, p.332-6, (2012) Read More / View Supplemental Materials
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RNA-SeQC: RNA-seq metrics for quality control and process optimization.Deluca, DS, Levin JZ, Sivachenko A., Fennell T., Nazaire MD, Williams C., Reich M., Winckler W., and Getz G. Bioinformatics (Oxford, England), 2012/06/01, Volume 28, Issue 11, p.1530-2, (2012) Read More / View Supplemental Materials
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Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacology.Kokel, D., Rennekamp AJ, Shah AH, Liebel U., and Peterson RT Trends in biotechnology, 2012/05/29, (2012) Read More / View Supplemental Materials
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Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy.Huillard, E., Hashizume R., Phillips JJ, Griveau A., Ihrie RA, Aoki Y., Nicolaides T., Perry A., Waldman T., McMahon M., Weiss WA, Petritsch C., James CD, and Rowitch DH Proceedings of the National Academy of Sciences of the United States of America, 2012/05/29, Volume 109, Issue 22, p.8710-5, (2012) Read More / View Supplemental Materials
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Exome sequencing and the genetic basis of complex traits.Kiezun, A., Garimella K., Do R., Stitziel NO, Neale BM, McLaren PJ, Gupta N., Sklar P., Sullivan PF, Moran JL, Hultman CM, Lichtenstein P., Magnusson P., Lehner T., Shugart YY, Price AL, de Bakker PI, Purcell SM, and Sunyaev SR Nature genetics, 2012/05/29, Volume 44, Issue 6, p.623-30, (2012) Read More / View Supplemental Materials
Exploring the variation within.Macosko, EZ, and McCarroll SA Nature genetics, 2012/05/29, Volume 44, Issue 6, p.614-6, (2012) Read More / View Supplemental Materials
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A Keystone for ncRNA.Hacisuleyman, E., Cabili MN, and Rinn JL Genome biology, 2012/05/25, Volume 13, Issue 5, p.315, (2012) Read More / View Supplemental Materials
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Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation.Jain, M., Nilsson R., Sharma S., Madhusudhan N., Kitami T., Souza AL, Kafri R., Kirschner MW, Clish CB, and Mootha VK Science (New York, N.Y.), 2012/05/25, Volume 336, Issue 6084, p.1040-4, (2012) Read More / View Supplemental Materials
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Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening.Stanley, SA, Grant SS, Kawate T., Iwase N., Shimizu M., Wivagg C., Silvis M., Kazyanskaya E., Aquadro J., Golas A., FitzGerald M., Dai H., Zhang L., and Hung DT ACS chemical biology, 2012/05/21, (2012) Read More / View Supplemental Materials
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Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer.Barbieri, CE, Baca SC, Lawrence MS, Demichelis F., Blattner M., Theurillat JP, White TA, Stojanov P., Van Allen E., Stransky N., Nickerson E., Chae SS, Boysen G., Auclair D., Onofrio RC, Park K., Kitabayashi N., MacDonald TY, Sheikh K., Vuong T., et al. Nature genetics, 2012/05/20, Volume 44, Issue 6, p.685-9, (2012) Read More / View Supplemental Materials
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Extremely low-coverage sequencing and imputation increases power for genome-wide association studies.Pasaniuc, B., Rohland N., McLaren PJ, Garimella K., Zaitlen N., Li H., Gupta N., Neale BM, Daly M. J., Sklar P., Sullivan PF, Bergen S., Moran JL, Hultman CM, Lichtenstein P., Magnusson P., Purcell SM, Haas DW, Liang L., Sunyaev S., et al. Nature genetics, 2012/05/20, Volume 44, Issue 6, p.631-5, (2012) Read More / View Supplemental Materials
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mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.Yilmaz, OH, Katajisto P., Lamming DW, Gültekin Y., Bauer-Rowe KE, Sengupta S., Birsoy K., Dursun A., Yilmaz VO, Selig M., Nielsen GP, Mino-Kenudson M., Zukerberg LR, Bhan AK, Deshpande V., and Sabatini DM Nature, 2012/05/20, (2012) Read More / View Supplemental Materials
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Evolutionary diversity of the mitochondrial calcium uniporter.Bick, AG, Calvo SE, and Mootha VK Science (New York, N.Y.), 2012/05/18, Volume 336, Issue 6083, p.886, (2012) Read More / View Supplemental Materials
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Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.Voight, BF, Peloso GM, Orho-Melander M., Frikke-Schmidt R., Barbalic M., Jensen MK, Hindy G., Hólm H., Ding EL, Johnson T., Schunkert H., Samani NJ, Clarke R., Hopewell JC, Thompson JF, Li M., Thorleifsson G., Newton-Cheh C., Musunuru K., Pirruccello JP, et al. Lancet, 2012/05/17, (2012) Read More / View Supplemental Materials
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Identification of a selective small molecule inhibitor of breast cancer stem cells.Germain, AR, Carmody LC, Morgan B., Fernandez C., Forbeck E., Lewis TA, Nag PP, Ting A., VerPlank L., Feng Y., Perez JR, Dandapani S., Palmer M., Lander E. S., Gupta PB, Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2012/05/15, Volume 22, Issue 10, p.3571-4, (2012) Read More / View Supplemental Materials
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A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.Manning, AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N., Chen H., Rybin D., Liu CT, Bielak LF, Prokopenko I., Amin N., Barnes D., Cadby G., Hottenga JJ, Ingelsson E., Jackson AU, Johnson T., Kanoni S., Ladenvall C., Lagou V., et al. Nature genetics, 2012/05/13, Volume 44, Issue 6, p.659-669, (2012) Read More / View Supplemental Materials
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Melanoma genome sequencing reveals frequent PREX2 mutations.Berger, MF, Hodis E., Heffernan TP, Deribe YL, Lawrence MS, Protopopov A., Ivanova E., Watson IR, Nickerson E., Ghosh P., Zhang H., Zeid R., Ren X., Cibulskis K., Sivachenko AY, Wagle N., Sucker A., Sougnez C., Onofrio R., Ambrogio L., et al. Nature, 2012/05/09, Volume 485, Issue 7399, p.502-6, (2012) Read More / View Supplemental Materials
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Apoptotic Cells Are Cleared by Directional Migration and elmo1- Dependent Macrophage Engulfment.van Ham, TJ, Kokel D., and Peterson RT Current biology : CB, 2012/05/08, Volume 22, Issue 9, p.830-6, (2012) Read More / View Supplemental Materials
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Exploring single-sample SNP and INDEL calling with whole-genome de novo assembly.Li, H. Bioinformatics (Oxford, England), 2012/05/07, (2012) Read More / View Supplemental Materials
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A Method of Moments Estimator for Random Effect Multivariate Meta-Analysis.Chen, H., Manning AK, and Dupuis J. Biometrics, 2012/05/02, (2012) Read More / View Supplemental Materials
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Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells.Brown-Endres, L., Schoenfeld D., Tian F., Kim HG, Namba T., Muñoz-Fontela C., Mandinova A., Aaronson SA, and Lee SW Cancer research, 2012/05/01, Volume 72, Issue 9, p.2373-82, (2012) Read More / View Supplemental Materials
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Modification site localization scoring: strategies and performance.Chalkley, RJ, and Clauser KR Molecular & cellular proteomics : MCP, 2012/05/01, Volume 11, Issue 5, p.3-14, (2012) Read More / View Supplemental Materials
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Overcoming fluconazole resistance in Candida albicans clinical isolates with tetracyclic indoles.Youngsaye, W., Dockendorff C., Vincent B., Hartland CL, Bittker JA, Dandapani S., Palmer M., Whitesell L., Lindquist S., Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2012/05/01, Volume 22, Issue 9, p.3362-5, (2012) Read More / View Supplemental Materials
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A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma.Yuan, Y., Wang Q., Paulk J., Kubicek S., Kemp MM, Adams DJ, Shamji AF, Wagner BK, and Schreiber SL ACS chemical biology, 2012/04/30, (2012) Read More / View Supplemental Materials
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Absolute quantification of somatic DNA alterations in human cancer.Carter, SL, Cibulskis K., Helman E., McKenna A., Shen H., Zack T., Laird PW, Onofrio RC, Winckler W., Weir BA, Beroukhim R., Pellman D., Levine DA, Lander E. S., Meyerson M., and Getz G. Nature biotechnology, 2012/04/29, (2012) Read More / View Supplemental Materials
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Reduced Expression of Ribosomal Proteins Relieves MicroRNA-Mediated Repression.Janas, MM, Wang E., Love T., Harris AS, Stevenson K., Semmelmann K., Shaffer JM, Chen PH, Doench JG, Yerramilli SV, Neuberg DS, Iliopoulos D., Housman DE, Burge CB, and Novina CD Molecular cell, 2012/04/27, Volume 46, Issue 2, p.171-86, (2012) Read More / View Supplemental Materials
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Sequencing Chromosomal Abnormalities Reveals Neurodevelopmental Loci that Confer Risk across Diagnostic Boundaries.Talkowski, ME, Rosenfeld JA, Blumenthal I., Pillalamarri V., Chiang C., Heilbut A., Ernst C., Hanscom C., Rossin E., Lindgren AM, Pereira S., Ruderfer D., Kirby A., Ripke S., Harris DJ, Lee JH, Ha K., Kim HG, Solomon BD, Gropman AL, et al. Cell, 2012/04/27, Volume 149, Issue 3, p.525-37, (2012) Read More / View Supplemental Materials
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Apolipoprotein E Genotype Predicts Hematoma Expansion in Lobar Intracerebral Hemorrhage.Brouwers, HB, Biffi A., Ayres AM, Schwab K., Cortellini L., Romero JM, Rost NS, Viswanathan A., Greenberg SM, Rosand J., and Goldstein JN Stroke; a journal of cerebral circulation, 2012/04/24, (2012) Read More / View Supplemental Materials
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Sex-specific influence of DRD2 on ADHD-type temperament in a large population-based birth cohort.Nyman, ES, Loukola A., Varilo T., Taanila A., Hurtig T., Moilanen I., Loo S., McGough JJ, Järvelin MR, Smalley SL, Nelson SF, and Peltonen L. Psychiatric genetics, 2012/04/23, (2012) Read More / View Supplemental Materials
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An image analysis toolbox for high-throughput C. elegans assays.Wählby, C., Kamentsky L., Liu ZH, Riklin-Raviv T., Conery AL, O'Rourke EJ, Sokolnicki KL, Visvikis O., Ljosa V., Irazoqui JE, Golland P., Ruvkun G., Ausubel FM, and Carpenter AE Nature methods, 2012/04/22, (2012) Read More / View Supplemental Materials
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Not lost in translation: stepwise regulation of microRNA targets.Janas, MM, and Novina CD The EMBO journal, 2012/04/20, (2012) Read More / View Supplemental Materials
Chemical Genomics Identifies Small-Molecule MCL1 Repressors and BCL-xL as a Predictor of MCL1 Dependency.Wei, G., Margolin AA, Haery L., Brown E., Cucolo L., Julian B., Shehata S., Kung AL, Beroukhim R., and Golub T. R. Cancer cell, 2012/04/17, Volume 21, Issue 4, p.547-62, (2012) Read More / View Supplemental Materials
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INRICH: Interval-based Enrichment Analysis for Genome Wide Association Studies.Lee, PH, O'Dushlaine C., Thomas B., and Purcell SM Bioinformatics (Oxford, England), 2012/04/17, (2012) Read More / View Supplemental Materials
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RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities.Barczak, AK, Gomez JE, Kaufmann BB, Hinson ER, Cosimi L., Borowsky ML, Onderdonk AB, Stanley SA, Kaur D., Bryant KF, Knipe DM, Sloutsky A., and Hung DT Proceedings of the National Academy of Sciences of the United States of America, 2012/04/17, Volume 109, Issue 16, p.6217-22, (2012) Read More / View Supplemental Materials
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Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair.Reynolds, JJ, Walker AK, Gilmore EC, Walsh CA, and Caldecott KW Nucleic acids research, 2012/04/15, (2012) Read More / View Supplemental Materials
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pIRS: Profile based Illumina pair-end Reads Simulator.Hu, X., Yuan J., Shi Y., Lu J., Liu B., Li Z., Chen Y., Mu D., Zhang H., Li N., Yue Z., Bai F., Li H., and An WF Bioinformatics (Oxford, England), 2012/04/15, (2012) Read More / View Supplemental Materials
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Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.Udeshi, ND, Mani D. R., Eisenhaure T., Mertins P., Jaffe JD, Clauser KR, Hacohen N., and Carr SA Molecular & cellular proteomics : MCP, 2012/04/14, (2012) Read More / View Supplemental Materials
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Harnessing genomics and genome biology to understand malaria biology.Volkman, SK, Neafsey DE, Schaffner SF, Park DJ, and Wirth DF Nature reviews. Genetics, 2012/04/12, Volume 13, Issue 5, p.315-28, (2012) Read More / View Supplemental Materials
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Parametric modeling of cellular state transitions as measured with flow cytometry.Ho, HJ, Lin TI, Chang HH, Haase SB, Huang S., and Pyne S. BMC bioinformatics, 2012/04/12, Volume 13 Suppl 5, p.S5, (2012) Read More / View Supplemental Materials
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Fast and accurate inference of local ancestry in Latino populations.Baran, Y., Pasaniuc B., Sankararaman S., Torgerson DG, Gignoux C., Eng C., Rodriguez-Cintron W., Chapela R., Ford JG, Avila PC, Rodriguez-Santana J., Burchard EG, and Halperin E. Bioinformatics (Oxford, England), 2012/04/11, (2012) Read More / View Supplemental Materials
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Alzheimer Disease Susceptibility Loci: Evidence for a Protein Network under Natural Selection.Raj, T., Shulman JM, Keenan BT, Chibnik LB, Evans DA, Bennett DA, Stranger BE, and De Jager PL American journal of human genetics, 2012/04/06, Volume 90, Issue 4, p.720-6, (2012) Read More / View Supplemental Materials
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The genomic basis of adaptive evolution in threespine sticklebacks.Jones, FC, Grabherr MG, Chan YF, Russell P., Mauceli E., Johnson J., Swofford R., Pirun M., Zody MC, White S., Birney E., Searle S., Schmutz J., Grimwood J., Dickson MC, Myers RM, Miller CT, Summers BR, Knecht AK, Brady SD, et al. Nature, 2012/04/04, Volume 484, Issue 7392, p.55-61, (2012) Read More / View Supplemental Materials
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Patterns and rates of exonic de novo mutations in autism spectrum disorders.Neale, BM, Kou Y., Liu L., Ma'ayan A., Samocha KE, Sabo A., Lin CF, Stevens C., Wang LS, Makarov V., Polak P., Yoon S., Maguire J., Crawford EL, Campbell NG, Geller ET, Valladares O., Schafer C., Liu H., Zhao T., et al. Nature, 2012/04/04, (2012) Read More / View Supplemental Materials
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Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells.Kubicek, S., Gilbert JC, Fomina-Yadlin D., Gitlin AD, Yuan Y., Wagner FF, Holson EB, Luo T., Lewis TA, Taylor B., Gupta S., Shamji AF, Wagner BK, Clemons PA, and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2012/04/03, Volume 109, Issue 14, p.5364-9, (2012) Read More / View Supplemental Materials
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.Barretina, J., Caponigro G., Stransky N., Venkatesan K., Margolin AA, Kim S., Wilson CJ, Lehár J., Kryukov GV, Sonkin D., Reddy A., Liu M., Murray L., Berger MF, Monahan JE, Morais P., Meltzer J., Korejwa A., Jané-Valbuena J., Mapa FA, et al. Nature, 2012/03/28, Volume 483, Issue 7391, p.603-7, (2012) Read More / View Supplemental Materials
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A unique regulatory phase of DNA methylation in the early mammalian embryo.Smith, ZD, Chan MM, Mikkelsen TS, Gu H., Gnirke A., Regev A., and Meissner A. Nature, 2012/03/28, Volume 484, Issue 7394, p.339-44, (2012) Read More / View Supplemental Materials
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Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis.Stahl, EA, Wegmann D., Trynka G., Gutierrez-Achury J., Do R., Voight BF, Kraft P., Chen R., Kallberg HJ, Kurreeman FA, Diabetes Genetics Replication and Meta-analysis Consortium, Myocardial Infarction Genetics Consortium, Kathiresan S., Wijmenga C., Gregersen PK, Alfredsson L., Siminovitch KA, Worthington J., de Bakker PI, Raychaudhuri S., et al. Nature genetics, 2012/03/25, (2012) Read More / View Supplemental Materials
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Common variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/2), adiponectin concentrations, and diabetes incidence in the Diabetes Prevention Program.Mather, KJ, Christophi CA, Jablonski KA, Knowler WC, Goldberg RB, Kahn SE, Spector T., Dastani Z., Waterworth D., Richards JB, Funahashi T., Pi-Sunyer FX, Pollin TI, Florez JC, Franks PW, and for the Diabetes Prevention Program Research Group Diabetic medicine : a journal of the British Diabetic Association, 2012/03/24, (2012) Read More / View Supplemental Materials
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Quantitative assessment of ChIP-grade antibodies directed against histone modifications reveals patterns of co-occurring marks on histone protein molecules.Peach, SE, Rudomin EL, Udeshi ND, Carr SA, and Jaffe JD Molecular & cellular proteomics : MCP, 2012/03/23, (2012) Read More / View Supplemental Materials
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Sonic hedgehog expression in corticofugal projection neurons directs cortical microcircuit formation.Harwell, CC, Parker PR, Gee SM, Okada A., McConnell SK, Kreitzer AC, and Kriegstein AR Neuron, 2012/03/22, Volume 73, Issue 6, p.1116-26, (2012) Read More / View Supplemental Materials
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A tell-tail sign of chromatin: histone mutations drive pediatric glioblastoma.Rheinbay, E., Louis DN, Bernstein BE, and Suvà ML Cancer cell, 2012/03/20, Volume 21, Issue 3, p.329-31, (2012) Read More / View Supplemental Materials
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Evidence that nuclear factor IA inhibits repair after white matter injury.Fancy, SP, Glasgow SM, Finley M., Rowitch DH, and Deneen B. Annals of neurology, 2012/03/19, (2012) Read More / View Supplemental Materials
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Rapid, field-deployable method for genotyping and discovery of drug-resistance single nucleotide polymorphisms in Plasmodium falciparum.Daniels, R., Ndiaye D., Wall M., McKinney J., Séne PD, Sabeti PC, Volkman SK, Mboup S., and Wirth DF Antimicrobial agents and chemotherapy, 2012/03/19, (2012) Read More / View Supplemental Materials
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Genetics of human cardiovascular disease.Kathiresan, S., and Srivastava D. Cell, 2012/03/16, Volume 148, Issue 6, p.1242-57, (2012) Read More / View Supplemental Materials
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Reprogramming Cellular Identity for Regenerative Medicine.Cherry, AB, and Daley GQ Cell, 2012/03/16, Volume 148, Issue 6, p.1110-1122, (2012) Read More / View Supplemental Materials
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2011 Curt Stern Award Address.Altshuler, D. American journal of human genetics, 2012/03/09, Volume 90, Issue 3, p.407-409, (2012) Read More / View Supplemental Materials
Common SNP-Based Haplotype Analysis of the 4p16.3 Huntington Disease Gene Region.Lee, JM, Gillis T., Mysore JS, Ramos EM, Myers RH, Hayden MR, Morrison PJ, Nance M., Ross CA, Margolis RL, Squitieri F., Griguoli A., Di Donato S., Gomez-Tortosa E., Ayuso C., Suchowersky O., Trent RJ, McCusker E., Novelletto A., Frontali M., et al. American journal of human genetics, 2012/03/09, Volume 90, Issue 3, p.434-444, (2012) Read More / View Supplemental Materials
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Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci.Saxena, R., Elbers CC, Guo Y., Peter I., Gaunt TR, Mega JL, Lanktree MB, Tare A., Castillo BA, Li YR, Johnson T., Bruinenberg M., Gilbert-Diamond D., Rajagopalan R., Voight BF, Balasubramanyam A., Barnard J., Bauer F., Baumert J., Bhangale T., et al. American journal of human genetics, 2012/03/09, Volume 90, Issue 3, p.410-425, (2012) Read More / View Supplemental Materials
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Use of a Multiethnic Approach to Identify Rheumatoid- Arthritis-Susceptibility Loci, 1p36 and 17q12.Kurreeman, FA, Stahl EA, Okada Y., Liao K., Diogo D., Raychaudhuri S., Freudenberg J., Kochi Y., Patsopoulos NA, Gupta N., investigators CLEAR, Sandor C., Bang SY, Lee HS, Padyukov L., Suzuki A., Siminovitch K., Worthington J., Gregersen PK, Hughes LB, et al. American journal of human genetics, 2012/03/09, Volume 90, Issue 3, p.524-532, (2012) Read More / View Supplemental Materials
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Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor.Dockendorff, C., Aisiku O., VerPlank L., Dilks JR, Smith DA, Gunnink SF, Dowal L., Negri J., Palmer M., Macpherson L., Schreiber SL, and Flaumenhaft R. ACS medicinal chemistry letters, 2012/03/08, Volume 3, Issue 3, p.232-237, (2012) Read More / View Supplemental Materials
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Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing.Lohr, JG, Stojanov P., Lawrence MS, Auclair D., Chapuy B., Sougnez C., Cruz-Gordillo P., Knoechel B., Asmann YW, Slager SL, Novak AJ, Dogan A., Ansell SM, Link BK, Zou L., Gould J., Saksena G., Stransky N., Rangel-Escareño C., Fernandez-Lopez JC, et al. Proceedings of the National Academy of Sciences of the United States of America, 2012/03/06, Volume 109, Issue 10, p.3879-84, (2012) Read More / View Supplemental Materials
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Chromatin-modifying enzymes as modulators of reprogramming.Onder, TT, Kara N., Cherry A., Sinha AU, Zhu N., Bernt KM, Cahan P., Marcarci BO, Unternaehrer J., Gupta PB, Lander E. S., Armstrong SA, and Daley GQ Nature, 2012/03/04, Volume 483, Issue 7391, p.598-602, (2012) Read More / View Supplemental Materials
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Circumventing cancer drug resistance in the era of personalized medicine.Garraway, LA, and Jänne PA Cancer discovery, 2012/03/01, Volume 2, Issue 3, p.214-26, (2012) Read More / View Supplemental Materials
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Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks.Trapnell, C., Roberts A., Goff L., Pertea G., Kim D., Kelley DR, Pimentel H., Salzberg SL, Rinn JL, and Pachter L. Nature protocols, 2012/03/01, Volume 7, Issue 3, p.562-78, (2012) Read More / View Supplemental Materials
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Genome-wide association studies of schizophrenia: does bigger lead to better results?Bergen, SE, and Petryshen TL Current opinion in psychiatry, 2012/03/01, Volume 25, Issue 2, p.76-82, (2012) Read More / View Supplemental Materials
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High-Throughput RT-PCR for small-molecule screening assays.Bittker, JA Current protocols in chemical biology, 2012/03/01, Volume 4, Issue 1, p.49-63, (2012) Read More / View Supplemental Materials
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Highly sensitive and specific detection of rare variants in mixed viral populations from massively parallel sequence data.Macalalad, AR, Zody MC, Charlebois P., Lennon NJ, Newman RM, Malboeuf CM, Ryan EM, Boutwell CL, Power KA, Brackney DE, Pesko KN, Levin JZ, Ebel GD, Allen TM, Birren BW, and Henn MR PLoS computational biology, 2012/03/01, Volume 8, Issue 3, p.e1002417, (2012) Read More / View Supplemental Materials
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MYC Is Activated by USP2a-Mediated Modulation of MicroRNAs in Prostate Cancer.Benassi, B., Flavin R., Marchionni L., Zanata S., Pan Y., Chowdhury D., Marani M., Strano S., Muti P., Blandino G., and Loda M. Cancer discovery, 2012/03/01, Volume 2, Issue 3, p.236-247, (2012) Read More / View Supplemental Materials
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