Scientific Publications

Search by Keyword(s)
Found 3629 results

Search Results

2015
MERAV: a tool for comparing gene expression across human tissues and cell types.Shaul, YD, Yuan B., Thiru P., Nutter-Upham A., McCallum S., Lanzkron C., Bell GW, and Sabatini DM Nucleic acids research, 2015/11/30, (2015) Read More / View Supplemental Materials
Abstract
Addendum: A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages.Lu, H., Clauser KR, Tam WL, Fröse J., Ye X., Eaton EN, Reinhardt F., Donnenberg VS, Bhargava R., Carr SA, and Weinberg R. A. Nature cell biology, 2015/11/27, Volume 17, Issue 12, p.1607, (2015) Read More / View Supplemental Materials
Resources for the design of CRISPR gene editing experiments.Graham, DB, and Root DE Genome biology, 2015/11/27, Volume 16, Issue 1, p.260, (2015) Read More / View Supplemental Materials
Abstract
Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy.Dejanovic, B., Djémié T., Grünewald N., Suls A., Kress V., Hetsch F., Craiu D., Zemel M., Gormley P., Lal D., group EuroEPINOMICS Dravet working, Myers CT, Mefford HC, Palotie A., Helbig I., Meier JC, De Jonghe P., Weckhuysen S., and Schwarz G. EMBO molecular medicine, 2015/11/27, (2015) Read More / View Supplemental Materials
Abstract
The DNA Ligase IV Syndrome R278H Mutation Impairs B Lymphopoiesis via Error-Prone Nonhomologous End-Joining.Park, J., Welner RS, Chan MY, Troppito L., Staber PB, Tenen D. G., and Yan CT Journal of immunology (Baltimore, Md. : 1950), 2015/11/25, (2015) Read More / View Supplemental Materials
Abstract
The structure and timescales of heat perception in larval zebrafish.Haesemeyer, M., Robson DN, Li JM, Schier AF, and Engert F. Cell systems, 2015/11/25, Volume 1, Issue 5, p.338-348, (2015) Read More / View Supplemental Materials
Abstract
EDARV370A associated facial characteristics in Uyghur population revealing further pleiotropic effects.Peng, Q., Li J., Tan J., Yang Y., Zhang M., Wu S., Liu Y., Zhang J., Qin P., Guan Y., Jiao Y., Zhang Z., Sabeti PC, Tang K., Xu S., Jin L., and Wang S. Human genetics, 2015/11/24, (2015) Read More / View Supplemental Materials
Abstract
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.Felix, JF, Bradfield JP, Monnereau C., van der Valk RJ, Stergiakouli E., Chesi A., Gaillard R., Feenstra B., Thiering E., Kreiner-Møller E., Mahajan A., Pitkänen N., Joro R., Cavadino A., Huikari V., Franks S., Groen-Blokhuis MM, Cousminer DL, Marsh JA, Lehtimäki T., et al. Human molecular genetics, 2015/11/24, (2015) Read More / View Supplemental Materials
Abstract
Smart nanosystems: Bio-inspired technologies that interact with the host environment.Kwon, EJ, Lo JH, and Bhatia SN Proceedings of the National Academy of Sciences of the United States of America, 2015/11/24, Volume 112, Issue 47, p.14460-6, (2015) Read More / View Supplemental Materials
Abstract
Synthetic biology devices for in vitro and in vivo diagnostics.Slomovic, S., Pardee K., and Collins JJ Proceedings of the National Academy of Sciences of the United States of America, 2015/11/24, Volume 112, Issue 47, p.14429-35, (2015) Read More / View Supplemental Materials
Abstract
Whole-exome sequencing of over 4,100 men of African ancestry and prostate cancer risk.Rand, KA, Rohland N., Tandon A., Stram A., Sheng X., Do R., Pasaniuc B., Allen A., Quinque D., Mallick S., Le Marchand L., Kaggwa S., Lubwama A., African Ancestry Prostate Cancer GWAS Consortium, consortium Ellipse/GAME-ON, Stram DO, Watya S., Henderson BE, Conti DV, Reich D., et al. Human molecular genetics, 2015/11/24, (2015) Read More / View Supplemental Materials
Abstract
Advances in discovering small molecules to probe protein function in a systems context.Doyle, SK, Pop MS, Evans HL, and Koehler AN Current opinion in chemical biology, 2015/11/23, Volume 30, p.28-36, (2015) Read More / View Supplemental Materials
Abstract
Genome-wide patterns of selection in 230 ancient Eurasians.Mathieson, I., Lazaridis I., Rohland N., Mallick S., Patterson N., Roodenberg SA, Harney E., Stewardson K., Fernandes D., Novak M., Sirak K., Gamba C., Jones ER, Llamas B., Dryomov S., Pickrell J., Arsuaga JL, de Castro JM, Carbonell E., Gerritsen F., et al. Nature, 2015/11/23, (2015) Read More / View Supplemental Materials
Abstract
HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis.Ombrello, MJ, Remmers EF, Tachmazidou I., Grom A., Foell D., Haas JP, Martini A., Gattorno M., Özen S., Prahalad S., Zeft AS, Bohnsack JF, Mellins ED, Ilowite NT, Russo R., Len C., Hilario MO, Oliveira S., Yeung RS, Rosenberg A., et al. Proceedings of the National Academy of Sciences of the United States of America, 2015/11/23, (2015) Read More / View Supplemental Materials
Abstract
Prediction of Sudden Cardiac Death with Automated High-Throughput Analysis of Heterogeneity in Standard Resting 12-Lead Electrocardiogram.Kenttä, TV, Nearing BD, Porthan K., Tikkanen JT, Viitasalo M., Nieminen MS, Salomaa V., Oikarinen L., Jula A., Kontula K., Newton-Cheh C., Huikuri HV, and Verrier RL Heart rhythm : the official journal of the Heart Rhythm Society, 2015/11/23, (2015) Read More / View Supplemental Materials
Abstract
The resurgence of phenotypic screening in drug discovery and development.Wagner, BK Expert opinion on drug discovery, 2015/11/23, (2015) Read More / View Supplemental Materials
Abstract
Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathy.Chen, H., Ren S., Clish C., Jain M., Mootha V., McCaffery JM, and Chan DC The Journal of cell biology, 2015/11/23, Volume 211, Issue 4, p.795-805, (2015) Read More / View Supplemental Materials
Abstract
GEMS Project: A Platform to Investigate Multiple Sclerosis Risk.Xia, Z., White CC, Owen EK, Von Korff A., Clarkson SR, McCabe CA, Cimpean M., Winn PA, Hoesing A., Steele SU, Cortese IC, Chitnis T., Weiner HL, Reich DS, Chibnik LB, and De Jager PL Annals of neurology, 2015/11/19, (2015) Read More / View Supplemental Materials
Abstract
Jagged 1 Rescues the Duchenne Muscular Dystrophy Phenotype.Vieira, NM, Elvers I., Alexander MS, Moreira YB, Eran A., Gomes JP, Marshall JL, Karlsson EK, Verjovski-Almeida S., Lindblad-Toh K., Kunkel LM, and Zatz M. Cell, 2015/11/19, Volume 163, Issue 5, p.1204-13, (2015) Read More / View Supplemental Materials
Abstract
Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway.Saxton, RA, Knockenhauer KE, Wolfson RL, Chantranupong L., Pacold ME, Wang T., Schwartz TU, and Sabatini DM Science (New York, N.Y.), 2015/11/19, (2015) Read More / View Supplemental Materials
Abstract
CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity.Wang, C., Yosef N., Gaublomme J., Wu C., Lee Y., Clish CB, Kaminski J., Xiao S., Zu Horste GM, Pawlak M., Kishi Y., Joller N., Karwacz K., Zhu C., Ordovas-Montanes M., Madi A., Wortman I., Miyazaki T., Sobel RA, Park H., et al. Cell, 2015/11/18, (2015) Read More / View Supplemental Materials
Abstract
Silent pericentromeric repeats speak out.Younger, ST, and Rinn JL Proceedings of the National Academy of Sciences of the United States of America, 2015/11/18, (2015) Read More / View Supplemental Materials
Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity.Gaublomme, JT, Yosef N., Lee Y., Gertner RS, Yang LV, Wu C., Pandolfi PP, Mak T., Satija R., Shalek AK, Kuchroo VK, Park H., and Regev A. Cell, 2015/11/18, (2015) Read More / View Supplemental Materials
Abstract
COMT Val 158 Met polymorphism is associated with nonverbal cognition following mild traumatic brain injury.Winkler, EA, Yue JK, McAllister TW, Temkin NR, Oh SS, Burchard EG, Hu D., Ferguson AR, Lingsma HF, Burke JF, Sorani MD, Rosand J., Yuh EL, Barber J., Tarapore PE, Gardner RC, Sharma S., Satris GG, Eng C., Puccio AM, et al. Neurogenetics, 2015/11/17, (2015) Read More / View Supplemental Materials
Abstract
Society for Pediatric Research 2015 Young Investigator Award: Genetics of human hematopoiesis-What patients can teach us about blood cell production.Wakabayashi, A., and Sankaran VG Pediatric research, 2015/11/17, (2015) Read More / View Supplemental Materials
Abstract
Stochastic electrotransport selectively enhances the transport of highly electromobile molecules.Kim, SY, Cho JH, Murray E., Bakh N., Choi H., Ohn K., Ruelas L., Hubbert A., McCue M., Vassallo SL, Keller PJ, and Chung K. Proceedings of the National Academy of Sciences of the United States of America, 2015/11/17, Volume 112, Issue 46, p.E6274-83, (2015) Read More / View Supplemental Materials
Abstract
The contribution of rare variation to prostate cancer heritability.Mancuso, N., Rohland N., Rand KA, Tandon A., Allen A., Quinque D., Mallick S., Li H., Stram A., Sheng X., Kote-Jarai Z., Easton DF, Eeles RA, consortium Practical, Le Marchand L., Lubwama A., Stram D., Watya S., Conti DV, Henderson B., et al. Nature genetics, 2015/11/16, (2015) Read More / View Supplemental Materials
Abstract
Does developmental timing of exposure to child maltreatment predict memory performance in adulthood? Results from a large, population-based sample.Dunn, EC, Busso DS, Raffeld MR, Smoller JW, Nelson CA, Doyle AE, and Luk G. Child abuse & neglect, 2015/11/13, (2015) Read More / View Supplemental Materials
Abstract
Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity.Dudani, JS, Jain PK, Kwong GA, Stevens KR, and Bhatia SN ACS nano, 2015/11/13, (2015) Read More / View Supplemental Materials
Abstract
Summaries of plenary, symposia, and oral sessions at the XXII World Congress of Psychiatric Genetics, Copenhagen, Denmark, 12-16 October 2014.Aas, M., Blokland GA, Chawner SJ, Choi SW, Estrada J., Forsingdal A., Friedrich M., Ganesham S., Hall L., Haslinger D., Huckins L., Loken E., Malan-Müller S., Martin J., Misiewicz Z., Pagliaroli L., Pardiñas AF, Pisanu C., Quadri G., Santoro ML, et al. Psychiatric genetics, 2015/11/12, (2015) Read More / View Supplemental Materials
Abstract
Definitive Localization of Intracellular Proteins: Novel Approach Using CRISPR-Cas9 Genome Editing, with Glucose 6-Phosphate Dehydrogenase as a Model.Spencer, NY, Yan Z., Cong L., Zhang Y., Engelhardt JF, and Stanton RC Analytical biochemistry, 2015/11/11, (2015) Read More / View Supplemental Materials
Abstract
Expansion of Interstitial Telomeric Sequences in Yeast.Aksenova, AY, Han G., Shishkin AA, Volkov KV, and Mirkin SM Cell reports, 2015/11/11, (2015) Read More / View Supplemental Materials
Abstract
Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates.Palamara, PF, Francioli LC, Wilton PR, Genovese G., Gusev A., Finucane HK, Sankararaman S., Genome of the Netherlands Consortium, Sunyaev SR, de Bakker PI, Wakeley J., Pe'er I., and Price AL American journal of human genetics, 2015/11/11, (2015) Read More / View Supplemental Materials
Abstract
Flow Cytometric Analysis of Mononuclear Phagocytes in Non-diseased Human Lung and Lung-draining Lymph Nodes.Desch, AN, Gibbings SL, Goyal R., Kolde R., Bednarek J., Bruno T., Slansky JE, Jacobelli J., Mason R., Ito Y., Messier E., Randolph GJ, Prabagar M., Atif SM, Segura E., Xavier RJ, Bratton DL, Janssen WJ, Henson PM, and Jakubzick CV American journal of respiratory and critical care medicine, 2015/11/09, (2015) Read More / View Supplemental Materials
Abstract
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.Gaulton, KJ, Ferreira T., Lee Y., Raimondo A., Mägi R., Reschen ME, Mahajan A., Locke A., William Rayner N., Robertson N., Scott RA, Prokopenko I., Scott LJ, Green T., Sparso T., Thuillier D., Yengo L., Grallert H., Wahl S., Frånberg M., et al. Nature genetics, 2015/11/09, (2015) Read More / View Supplemental Materials
Abstract
Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load.McLaren, PJ, Coulonges C., Bartha I., Lenz TL, Deutsch AJ, Bashirova A., Buchbinder S., Carrington MN, Cossarizza A., Dalmau J., De Luca A., Goedert JJ, Gurdasani D., Haas DW, Herbeck JT, Johnson EO, Kirk GD, Lambotte O., Luo M., Mallal S., et al. Proceedings of the National Academy of Sciences of the United States of America, 2015/11/09, (2015) Read More / View Supplemental Materials
Abstract
Shared genetic aetiology of puberty timing between sexes and with health-related outcomes.Day, FR, Bulik-Sullivan B., Hinds DA, Finucane HK, Murabito JM, Tung JY, Ong KK, and Perry JR Nature communications, 2015/11/09, Volume 6, p.8842, (2015) Read More / View Supplemental Materials
Abstract
SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2.Kim, KH, Kim W., Howard TP, Vazquez F., Tsherniak A., Wu JN, Wang W., Haswell JR, Walensky LD, Hahn WC, Orkin SH, and Roberts CW Nature medicine, 2015/11/09, (2015) Read More / View Supplemental Materials
Abstract
Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems.Shmakov, S., Abudayyeh OO, Makarova KS, Wolf YI, Gootenberg JS, Semenova E., Minakhin L., Joung J., Konermann S., Severinov K., Zhang F., and Koonin EV Molecular cell, 2015/11/05, Volume 60, Issue 3, p.385-97, (2015) Read More / View Supplemental Materials
Abstract
Draft Genome Sequence of Cercospora arachidicola, Causal Agent of Early Leaf Spot in Peanuts.Orner, VA, Cantonwine EG, Wang XM, Abouelleil A., Bochicchio J., Nusbaum C., Culbreath AK, Abdo Z., and Arias RS Genome announcements, 2015/11/05, Volume 3, Issue 6, (2015) Read More / View Supplemental Materials
Abstract
Functional implications of disease-specific variants in loci jointly associated to coeliac disease and rheumatoid arthritis.Gutierrez-Achury, J., Zorro MM, Ricaño-Ponce I., Zhernakova DV, consortium Coeliac Disease Immunochip consortium, RACI, Diogo D., Raychaudhuri S., Franke L., Trynka G., Wijmenga C., and Zhernakova A. Human molecular genetics, 2015/11/05, (2015) Read More / View Supplemental Materials
Abstract
LARS2 Variants Associated with Hydrops, Lactic Acidosis, Sideroblastic Anemia, and Multisystem Failure.Riley, LG, Rudinger-Thirion J., Schmitz-Abe K., Thorburn DR, Davis RL, Teo J., Arbuckle S., Cooper ST, Campagna DR, Frugier M., Markianos K., Sue CM, Fleming MD, and Christodoulou J. JIMD reports, 2015/11/05, (2015) Read More / View Supplemental Materials
Abstract
Two-Variance-Component Model Improves Genetic Prediction in Family Datasets.Tucker, G., Loh PR, MacLeod IM, Hayes BJ, Goddard ME, Berger B., and Price AL American journal of human genetics, 2015/11/05, Volume 97, Issue 5, p.677-90, (2015) Read More / View Supplemental Materials
Abstract
CellProfiler Tracer: exploring and validating high-throughput, time-lapse microscopy image data.Bray, MA, and Carpenter AE BMC bioinformatics, 2015/11/04, Volume 16, p.368, (2015) Read More / View Supplemental Materials
Abstract
Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomisation Meta-Analysis in the CARTA Consortium.Linneberg, A., Jacobsen RK, Skaaby T., Taylor AE, Fluharty ME, Jeppesen JL, Bjørngaard JH, Åsvold BO, Gabrielsen ME, Campbell A., Marioni RE, Kumari M., Marques-Vidal P., Kaakinen M., Cavadino A., Postmus I., Ahluwalia TS, Wannamethee SG, Lahti J., Räikkönen K., et al. Circulation. Cardiovascular genetics, 2015/11/04, (2015) Read More / View Supplemental Materials
Abstract
Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease.Karaca, E., Harel T., Pehlivan D., Jhangiani SN, Gambin T., Coban Akdemir Z., Gonzaga-Jauregui C., Erdin S., Bayram Y., Campbell IM, Hunter JV, Atik MM, Van Esch H., Yuan B., Wiszniewski W., Isikay S., Yesil G., Yuregir OO, Tug Bozdogan S., Aslan H., et al. Neuron, 2015/11/04, Volume 88, Issue 3, p.499-513, (2015) Read More / View Supplemental Materials
Abstract
History and genomic sequence analysis of the herpes simplex virus 1 KOS and KOS1.1 sub-strains.Colgrove, RC, Liu X., Griffiths A., Raja P., Deluca NA, Newman RM, Coen DM, and Knipe DM Virology, 2015/11/04, Volume 487, p.215-221, (2015) Read More / View Supplemental Materials
Abstract
Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage.Belenky, P., Ye JD, Porter CB, Cohen NR, Lobritz MA, Ferrante T., Jain S., Korry BJ, Schwarz EG, Walker GC, and Collins JJ Cell reports, 2015/11/03, Volume 13, Issue 5, p.968-80, (2015) Read More / View Supplemental Materials
Abstract
Complete Genome Sequences and Analysis of the Fusobacterium nucleatum subspecies animalis 7-1 Bacteriophage ɸFunu1 and ɸFunu2.Cochrane, K., McGuire AM, Priest ME, Abouelleil A., Cerqueira GC, Lo R., Earl AM, and Allen-Vercoe E. Anaerobe, 2015/11/03, (2015) Read More / View Supplemental Materials
Abstract
A Metabolic Signature of Mitochondrial Dysfunction Revealed through a Monogenic Form of Leigh Syndrome.Thompson Legault, J., Strittmatter L., Tardif J., Sharma R., Tremblay-Vaillancourt V., Aubut C., Boucher G., Clish CB, Cyr D., Daneault C., Waters PJ, LSFC Consortium, Vachon L., Morin C., Laprise C., Rioux JD, Mootha VK, and Des Rosiers C. Cell reports, 2015/11/03, Volume 13, Issue 5, p.981-9, (2015) Read More / View Supplemental Materials
Abstract
Characterization of Intestinal Microbiota in Ulcerative Colitis Patients with and without Primary Sclerosing Cholangitis.Kevans, D., Tyler AD, Holm K., Jørgensen KK, Vatn MH, Karlsen TH, Kaplan GG, Eksteen B., Gevers D., Hov JR, and Silverberg MS Journal of Crohn's & colitis, 2015/11/02, (2015) Read More / View Supplemental Materials
Abstract
Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis.Loh, PR, Bhatia G., Gusev A., Finucane HK, Bulik-Sullivan BK, Pollack SJ, Schizophrenia Working Group of the Psychiatric Genomics Consortium, de Candia TR, Lee SH, Wray NR, Kendler KS, O'Donovan MC, Neale BM, Patterson N., and Price AL Nature genetics, 2015/11/02, (2015) Read More / View Supplemental Materials
Abstract
Lifestyle and metformin ameliorate insulin sensitivity independently of the genetic burden of established insulin resistance variants in Diabetes Prevention Program participants.Hivert, MF, Christophi CA, Franks PW, Jablonski KA, Ehrmann DA, Kahn SE, Horton ES, Pollin TI, Mather KJ, Perreault L., Barrett-Connor E., Knowler WC, Florez JC, and Diabetes Prevention Program Research Group Diabetes, 2015/11/02, (2015) Read More / View Supplemental Materials
Abstract
50 Years of Emmonsia Disease in Humans: The Dramatic Emergence of a Cluster of Novel Fungal Pathogens.Schwartz, IS, Kenyon C., Feng P., Govender NP, Dukik K., Sigler L., Jiang Y., Stielow JB, Muñoz JF, Cuomo CA, Botha A., Stchigel AM, and de Hoog GS PLoS pathogens, 2015/11/01, Volume 11, Issue 11, p.e1005198, (2015) Read More / View Supplemental Materials
The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis.Pomerantz, MM, Li F., Takeda DY, Lenci R., Chonkar A., Chabot M., Cejas P., Vazquez F., Cook J., Shivdasani RA, Bowden M., Lis R., Hahn WC, Kantoff PW, Brown M., Loda M., Long HW, and Freedman ML Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1346-51, (2015) Read More / View Supplemental Materials
Abstract
Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes.Lipson, M., Loh PR, Sankararaman S., Patterson N., Berger B., and Reich D. PLoS genetics, 2015/11/01, Volume 11, Issue 11, p.e1005550, (2015) Read More / View Supplemental Materials
Abstract
Gender Disparity and Mutation Burden in Metastatic Melanoma.Gupta, S., Artomov M., Goggins W., Daly M., and Tsao H. Journal of the National Cancer Institute, 2015/11/01, Volume 107, Issue 11, (2015) Read More / View Supplemental Materials
Abstract
Genome-Wide Association Study of Golden Retrievers Identifies Germ-Line Risk Factors Predisposing to Mast Cell Tumours.Arendt, ML, Melin M., Tonomura N., Koltookian M., Courtay-Cahen C., Flindall N., Bass J., Boerkamp K., Megquir K., Youell L., Murphy S., McCarthy C., London C., Rutteman GR, Starkey M., and Lindblad-Toh K. PLoS genetics, 2015/11/01, Volume 11, Issue 11, p.e1005647, (2015) Read More / View Supplemental Materials
Abstract
The genomic landscape of juvenile myelomonocytic leukemia.Stieglitz, E., Taylor-Weiner AN, Chang TY, Gelston LC, Wang YD, Mazor T., Esquivel E., Yu A., Seepo S., Olsen SR, Rosenberg M., Archambeault SL, Abusin G., Beckman K., Brown PA, Briones M., Carcamo B., Cooper T., Dahl GV, Emanuel PD, et al. Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1326-33, (2015) Read More / View Supplemental Materials
Abstract
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.Day, FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N., Chasman DI, Stolk L., Finucane HK, Sulem P., Bulik-Sullivan B., Esko T., Johnson AD, Elks CE, Franceschini N., He C., Altmaier E., Brody JA, Franke LL, Huffman JE, Keller MF, et al. Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1294-303, (2015) Read More / View Supplemental Materials
Abstract
Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape.Shell, SS, Wang J., Lapierre P., Mir M., Chase MR, Pyle MM, Gawande R., Ahmad R., Sarracino DA, Ioerger TR, Fortune SM, Derbyshire KM, Wade JT, and Gray TA PLoS genetics, 2015/11/01, Volume 11, Issue 11, p.e1005641, (2015) Read More / View Supplemental Materials
Abstract
Whole-brain activity mapping onto a zebrafish brain atlas.Randlett, O., Wee CL, Naumann EA, Nnaemeka O., Schoppik D., Fitzgerald JE, Portugues R., Lacoste AM, Riegler C., Engert F., and Schier AF Nature methods, 2015/11/01, Volume 12, Issue 11, p.1039-1046, (2015) Read More / View Supplemental Materials
Abstract
Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women.Griesbeck, M., Ziegler S., Laffont S., Smith N., Chauveau L., Tomezsko P., Sharei A., Kourjian G., Porichis F., Hart M., Palmer CD, Sirignano M., Beisel C., Hildebrandt H., Cénac C., Villani AC, Diefenbach TJ, Le Gall S., Schwartz O., Herbeuval JP, et al. Journal of immunology (Baltimore, Md. : 1950), 2015/10/30, (2015) Read More / View Supplemental Materials
Abstract
Bifidobacteria exhibit social behavior through carbohydrate resource sharing in the gut.Milani, C., Andrea Lugli G., Duranti S., Turroni F., Mancabelli L., Ferrario C., Mangifesta M., Hevia A., Viappiani A., Scholz M., Arioli S., Sanchez B., Lane J., Ward DV, Hickey R., Mora D., Segata N., Margolles A., van Sinderen D., and Ventura M. Scientific reports, 2015/10/28, Volume 5, p.15782, (2015) Read More / View Supplemental Materials
Abstract
Fluid Spatial Dynamics of West Nile Virus in the USA: Rapid Spread in a Permissive Host Environment.Di Giallonardo, F., Geoghegan JL, Docherty DE, McLean RG, Zody MC, Qu J., Yang X., Birren BW, Malboeuf CM, Newman RM, Ip HS, and Holmes EC Journal of virology, 2015/10/28, (2015) Read More / View Supplemental Materials
Abstract
Small island, big genetic discoveries.Lettre, G., and Hirschhorn JN Nature genetics, 2015/10/28, Volume 47, Issue 11, p.1224-5, (2015) Read More / View Supplemental Materials
Abstract
Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.Song, J., Bergen SE, Di Florio A., Karlsson R., Charney A., Ruderfer DM, Stahl EA, Members of the International Cohort Collection for Bipolar Disorder(ICCBD), Chambert KD, Moran JL, Gordon-Smith K., Forty L., Green EK, Jones I., Jones L., Scolnick EM, Sklar P., Smoller JW, Lichtenstein P., Hultman C., et al. Molecular psychiatry, 2015/10/27, (2015) Read More / View Supplemental Materials
Abstract
A perspective on stem cell modeling of Amyotrophic Lateral Sclerosis.de Boer, AS, and Eggan K. Cell cycle (Georgetown, Tex.), 2015/10/27, (2015) Read More / View Supplemental Materials
Abstract
A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs.Choi, J., Lee S., Mallard W., Clement K., Tagliazucchi GM, Lim H., Choi IY, Ferrari F., Tsankov AM, Pop R., Lee G., Rinn JL, Meissner A., Park PJ, and Hochedlinger K. Nature biotechnology, 2015/10/26, (2015) Read More / View Supplemental Materials
Abstract
Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis.Wagschal, A., Najafi-Shoushtari SH, Wang L., Goedeke L., Sinha S., deLemos AS, Black JC, Ramírez CM, Li Y., Tewhey R., Hatoum I., Shah N., Lu Y., Kristo F., Psychogios N., Vrbanac V., Lu YC, Hla T., de Cabo R., Tsang JS, et al. Nature medicine, 2015/10/26, (2015) Read More / View Supplemental Materials
Abstract
Lenalidomide: deciphering mechanisms of action in myeloma, myelodysplastic syndrome and beyond.Guirguis, AA, and Ebert BL Current opinion in cell biology, 2015/10/26, Volume 37, p.61-67, (2015) Read More / View Supplemental Materials
Abstract
A qPCR ScoreCard quantifies the differentiation potential of human pluripotent stem cells.Tsankov, AM, Akopian V., Pop R., Chetty S., Gifford CA, Daheron L., Tsankova NM, and Meissner A. Nature biotechnology, 2015/10/26, (2015) Read More / View Supplemental Materials
Abstract
BGT: efficient and flexible genotype query across many samples.Li, H. Bioinformatics (Oxford, England), 2015/10/24, (2015) Read More / View Supplemental Materials
Abstract
Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes.Sanborn, AL, Rao SS, Huang SC, Durand NC, Huntley MH, Jewett AI, Bochkov ID, Chinnappan D., Cutkosky A., Li J., Geeting KP, Gnirke A., Melnikov A., McKenna D., Stamenova EK, Lander E. S., and Aiden EL Proceedings of the National Academy of Sciences of the United States of America, 2015/10/23, (2015) Read More / View Supplemental Materials
Abstract
Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.Raj, L., Ide T., Gurkar AU, Foley M., Schenone M., Li X., Tolliday NJ, Golub T. R., Carr SA, Shamji AF, Stern AM, Mandinova A., Schreiber SL, and Lee SW Nature, 2015/10/22, Volume 526, Issue 7574, p.596, (2015) Read More / View Supplemental Materials
Genome-wide genetic homogeneity between sexes and populations for human height and body mass index.Yang, J., Bakshi A., Zhu Z., Hemani G., Vinkhuyzen AA, Nolte IM, van Vliet-Ostaptchouk JV, Snieder H., study LifeLines Cohort, Esko T., Milani L., Mägi R., Metspalu A., Hamsten A., Magnusson PK, Pedersen NL, Ingelsson E., and Visscher PM Human molecular genetics, 2015/10/22, (2015) Read More / View Supplemental Materials
Abstract
Mutations driving CLL and their evolution in progression and relapse.Landau, DA, Tausch E., Taylor-Weiner AN, Stewart C., Reiter JG, Bahlo J., Kluth S., Bozic I., Lawrence M., Böttcher S., Carter SL, Cibulskis K., Mertens D., Sougnez CL, Rosenberg M., Hess JM, Edelmann J., Kless S., Kneba M., Ritgen M., et al. Nature, 2015/10/22, Volume 526, Issue 7574, p.525-30, (2015) Read More / View Supplemental Materials
Abstract
The transcriptional landscape of age in human peripheral blood.Peters, MJ, Joehanes R., Pilling LC, Schurmann C., Conneely KN, Powell J., Reinmaa E., Sutphin GL, Zhernakova A., Schramm K., Wilson YA, Kobes S., Tukiainen T., NABEC/UKBEC Consortium, Ramos YF, Göring HH, Fornage M., Liu Y., Gharib SA, Stranger BE, et al. Nature communications, 2015/10/22, Volume 6, p.8570, (2015) Read More / View Supplemental Materials
Abstract
Calcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapies.Wieder, N., and Greka A. Pediatric nephrology (Berlin, Germany), 2015/10/21, (2015) Read More / View Supplemental Materials
Abstract
Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine.Neafsey, DE, Juraska M., Bedford T., Benkeser D., Valim C., Griggs A., Lievens M., Abdulla S., Adjei S., Agbenyega T., Agnandji ST, Aide P., Anderson S., Ansong D., Aponte JJ, Asante KP, Bejon P., Birkett AJ, Bruls M., Connolly KM, et al. The New England journal of medicine, 2015/10/21, (2015) Read More / View Supplemental Materials
Abstract
BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology.Shankar, GM, Lelic N., Gill CM, Thorner AR, Van Hummelen P., Wisoff JH, Loeffler JS, Brastianos PK, Shin JH, Borges LF, Butler WE, Zagzag D., Brody RI, Duhaime AC, Taylor MD, Hawkins CE, Louis DN, Cahill DP, Curry WT, and Meyerson M. Acta neuropathologica, 2015/10/20, (2015) Read More / View Supplemental Materials
An integrative systems genetics approach reveals potential causal genes and pathways related to obesity.Kogelman, LJ, Zhernakova DV, Westra HJ, Cirera S., Fredholm M., Franke L., and Kadarmideen HN Genome medicine, 2015/10/20, Volume 7, Issue 1, p.105, (2015) Read More / View Supplemental Materials
Abstract
Oncogenic Signaling Adaptor Proteins.Luo, LY, and Hahn WC Journal of genetics and genomics = Yi chuan xue bao, 2015/10/20, Volume 42, Issue 10, p.521-9, (2015) Read More / View Supplemental Materials
Abstract
Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells.Giani, FC, Fiorini C., Wakabayashi A., Ludwig LS, Salem RM, Jobaliya CD, Regan SN, Ulirsch JC, Liang G., Steinberg-Shemer O., Guo MH, Esko T., Tong W., Brugnara C., Hirschhorn JN, Weiss MJ, Zon LI, Chou ST, French DL, Musunuru K., et al. Cell stem cell, 2015/10/20, (2015) Read More / View Supplemental Materials
Abstract
Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.Cao, Z., Conway KL, Heath RJ, Rush JS, Leshchiner ES, Ramirez-Ortiz ZG, Nedelsky NB, Huang H., Ng A., Gardet A., Cheng SC, Shamji AF, Rioux JD, Wijmenga C., Netea MG, Means TK, Daly M. J., and Xavier RJ Immunity, 2015/10/20, Volume 43, Issue 4, p.715-26, (2015) Read More / View Supplemental Materials
Abstract
Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution.Chen, XG, Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M., Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W., Peng H., Liu Y., Wu K., Chen J., Lirakis M., et al. Proceedings of the National Academy of Sciences of the United States of America, 2015/10/19, (2015) Read More / View Supplemental Materials
Abstract
Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset.Seashore-Ludlow, B., Rees MG, Cheah JH, Cokol M., Price EV, Coletti ME, Jones V., Bodycombe NE, Soule CK, Gould J., Alexander B., Li A., Montgomery P., Wawer MJ, Kuru N., Kotz JD, Hon CS, Munoz B., Liefeld T., Dančík V., et al. Cancer discovery, 2015/10/19, (2015) Read More / View Supplemental Materials
Abstract
Oct1 and OCA-B are selectively required for CD4 memory T cell function.Shakya, A., Goren A., Shalek A., German CN, Snook J., Kuchroo VK, Yosef N., Chan RC, Regev A., Williams MA, and Tantin D. The Journal of experimental medicine, 2015/10/19, (2015) Read More / View Supplemental Materials
Abstract
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.Cleynen, I., Boucher G., Jostins L., Schumm LP, Zeissig S., Ahmad T., Andersen V., Andrews JM, Annese V., Brand S., Brant SR, Cho JH, Daly M. J., Dubinsky M., Duerr RH, Ferguson LR, Franke A., Gearry RB, Goyette P., Hakonarson H., et al. Lancet (London, England), 2015/10/16, (2015) Read More / View Supplemental Materials
Abstract
A role for HLA-DRB1*1101 and DRB1*0801 in cognitive ability and its decline with age.Payton, A., Dawes P., Platt H., Morton CC, Moore DR, Massey J., Horan M., Ollier W., Munro KJ, and Pendleton N. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2015/10/16, (2015) Read More / View Supplemental Materials
Abstract
Some of the most interesting CASP11 targets through the eyes of their authors.Kryshtafovych, A., Moult J., Baslé A., Burgin A., Craig TK, Edwards RA, Fass D., Hartmann MD, Korycinski M., Lewis RJ, Lorimer D., Lupas AN, Newman J., Peat TS, Piepenbrink KH, Prahlad J., van Raaij MJ, Rohwer F., Segall AM, Seguritan V., et al. Proteins, 2015/10/16, (2015) Read More / View Supplemental Materials
Abstract
Stable inhibitory activity of regulatory T cells requires the transcription factor Helios.Kim, HJ, Barnitz RA, Kreslavsky T., Brown FD, Moffett H., Lemieux ME, Kaygusuz Y., Meissner T., Holderried TA, Chan S., Kastner P., Haining WN, and Cantor H. Science (New York, N.Y.), 2015/10/16, Volume 350, Issue 6258, p.334-9, (2015) Read More / View Supplemental Materials
Abstract
Building the foundation for genomics in precision medicine.Aronson, SJ, and Rehm HL Nature, 2015/10/15, Volume 526, Issue 7573, p.336-42, (2015) Read More / View Supplemental Materials
Abstract
Identification and characterization of essential genes in the human genome.Wang, T., Birsoy K., Hughes NW, Krupczak KM, Post Y., Wei JJ, Lander E. S., and Sabatini DM Science (New York, N.Y.), 2015/10/15, (2015) Read More / View Supplemental Materials
Abstract
Invasive Bladder Cancer: Genomic Insights and Therapeutic Promise.Kim, J., Akbani R., Creighton CJ, Lerner SP, Weinstein J. N., Getz G., and Kwiatkowski DJ Clinical cancer research : an official journal of the American Association for Cancer Research, 2015/10/15, Volume 21, Issue 20, p.4514-24, (2015) Read More / View Supplemental Materials
Abstract
Responses to Bacteria, Virus and Malaria Distinguish the Etiology of Pediatric Clinical Pneumonia.Valim, C., Ahmad R., Lanaspa M., Tan Y., Acácio S., Gillette MA, Almendinger KD, Milner DA Jr, Madrid L., Pellé K., Harezlak J., Silterra J., Alonso PL, Carr SA, Mesirov J. P., Wirth DF, Wiegand RC, and Bassat Q. American journal of respiratory and critical care medicine, 2015/10/15, (2015) Read More / View Supplemental Materials
Abstract
Reduced Sleep Spindles in Schizophrenia: A Treatable Endophenotype That Links Risk Genes to Impaired Cognition?Manoach, DS, Pan JQ, Purcell SM, and Stickgold R. Biological psychiatry, 2015/10/14, (2015) Read More / View Supplemental Materials
Abstract
Common Variants in DRD2 are Associated with Sleep Duration: The CARe Consortium.Cade, BE, Gottlieb DJ, Lauderdale DS, Bennett DA, Buchman AS, Buxbaum SG, De Jager PL, Evans DS, Fülöp T., Gharib SA, Johnson WC, Im HK, Larkin EK, Lee SK, Lim AS, Punjabi NM, Shin C., Stone KL, Tranah GJ, Weng J., et al. Human molecular genetics, 2015/10/13, (2015) Read More / View Supplemental Materials
Abstract
Hitting the Target in BRAF-Mutant Colorectal Cancer.Nagaraja, AK, and Bass AJ Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015/10/12, (2015) Read More / View Supplemental Materials
Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state.Rotem, A., Ram O., Shoresh N., Sperling RA, Goren A., Weitz DA, and Bernstein BE Nature biotechnology, 2015/10/12, (2015) Read More / View Supplemental Materials
Abstract