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2013
Connecting Genomic Alterations to Cancer Biology with Proteomics: The NCI Clinical Proteomic Tumor Analysis Consortium.Ellis, MJ, Gillette M., Carr SA, Paulovich AG, Smith RD, Rodland KK, Townsend RR, Kinsinger C., Mesri M., Rodriguez H., Liebler DC, and Clinical Proteomic Tumor Analysis Consortium(CPTAC) Cancer discovery, 2013/10/01, Volume 3, Issue 10, p.1108-12, (2013) Read More / View Supplemental Materials
Abstract
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.Ripke, S., O'Dushlaine C., Chambert K., Moran JL, Kähler AK, Akterin S., Bergen SE, Collins AL, Crowley JJ, Fromer M., Kim Y., Lee SH, Magnusson PK, Sanchez N., Stahl EA, Williams S., Wray NR, Xia K., Bettella F., Borglum AD, et al. Nature genetics, 2013/10/01, Volume 45, Issue 10, p.1150-9, (2013) Read More / View Supplemental Materials
Abstract
Large-scale identification of ubiquitination sites by mass spectrometry.Udeshi, ND, Mertins P., Svinkina T., and Carr SA Nature protocols, 2013/10/01, Volume 8, Issue 10, p.1950-60, (2013) Read More / View Supplemental Materials
Abstract
Small molecule inhibitors of zinc-dependent histone deacetylases.Wagner, FF, Weїwer M., Lewis MC, and Holson EB Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2013/10/01, Volume 10, Issue 4, p.589-604, (2013) Read More / View Supplemental Materials
Abstract
Stroke Genetics Network (SiGN) Study: Design and Rationale for a Genome-Wide Association Study of Ischemic Stroke Subtypes.Meschia, JF, Arnett DK, Ay H., Brown RD Jr, Benavente OR, Cole JW, de Bakker PI, Dichgans M., Doheny KF, Fornage M., Grewal RP, Gwinn K., Jern C., Conde JJ, Johnson JA, Jood K., Laurie CC, Lee JM, Lindgren A., Markus HS, et al. Stroke; a journal of cerebral circulation, 2013/10/01, Volume 44, Issue 10, p.2694-702, (2013) Read More / View Supplemental Materials
Abstract
Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors.Akbay, EA, Koyama S., Carretero J., Altabef A., Tchaicha JH, Christensen CL, Mikse OR, Cherniack AD, Beauchamp EM, Pugh TJ, Wilkerson MD, Fecci PE, Butaney M., Reibel JB, Soucheray M., Cohoon TJ, Janne PA, Meyerson M., Hayes DN, Shapiro GI, et al. Cancer discovery, 2013/09/27, (2013) Read More / View Supplemental Materials
Abstract
The Cancer Genome Atlas Pan-Cancer analysis project.Cancer Genome Atlas Research, Network, Genome Characterization Center, Chang K., Creighton CJ, Davis C., Donehower L., Drummond J., Wheeler D., Ally A., Balasundaram M., Birol I., Butterfield YS, Chu A., Chuah E., Chun HJ, Dhalla N., Guin R., Hirst M., Hirst C., Holt RA, et al. Nature genetics, 2013/09/26, Volume 45, Issue 10, p.1113-20, (2013) Read More / View Supplemental Materials
Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia.Stitziel, NO, Fouchier SW, Sjouke B., Peloso GM, Moscoso AM, Auer PL, Goel A., Gigante B., Barnes TA, Melander O., Orho-Melander M., Duga S., Sivapalaratnam S., Nikpay M., Martinelli N., Girelli D., Jackson RD, Kooperberg C., Lange LA, Ardissino D., et al. Arteriosclerosis, thrombosis, and vascular biology, 2013/09/26, (2013) Read More / View Supplemental Materials
Abstract
Pan-cancer patterns of somatic copy number alteration.Zack, TI, Schumacher SE, Carter SL, Cherniack AD, Saksena G., Tabak B., Lawrence MS, Zhang CZ, Wala J., Mermel CH, Sougnez C., Gabriel SB, Hernandez B., Shen H., Laird PW, Getz G., Meyerson M., and Beroukhim R. Nature genetics, 2013/09/26, Volume 45, Issue 10, p.1134-1140, (2013) Read More / View Supplemental Materials
Abstract
High reliability in respiratory rate assessment in children with respiratory symptomatology in a rural area in MozambiqueLanaspa, M., Valim C., Acacio S., Almendinger K., Ahmad R., Wiegand R., and Bassat Q. Journal of Tropical Pediatrics, 2013/09/25, (2013) Read More / View Supplemental Materials
Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization.Cho, J., Chen L., Sangji N., Okabe T., Yonesaka K., Francis JM, Flavin RJ, Johnson W., Kwon J., Yu S., Greulich HE, Johnson B. E., Eck MJ, Janne PA, Wong KK, and Meyerson M. Cancer research, 2013/09/24, (2013) Read More / View Supplemental Materials
Abstract
Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells.Li, BE, Gan T., Meyerson M., Rabbitts TH, and Ernst P. Blood, 2013/09/19, Volume 122, Issue 12, p.2039-46, (2013) Read More / View Supplemental Materials
Abstract
Colorectal Cancers from Distinct Ancestral Populations Show Variations in BRAF Mutation Frequency.Hanna, MC, Go C., Roden C., Jones RT, Pochanard P., Javed AY, Javed A., Mondal C., Palescandolo E., Van Hummelen P., Hatton C., Bass AJ, Chun SM, Na DC, Kim TI, Jang SJ, Osarogiagbon RU, Hahn WC, Meyerson M., Garraway LA, et al. PloS one, 2013/09/16, Volume 8, Issue 9, p.e74950, (2013) Read More / View Supplemental Materials
Abstract
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity.Ran, FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S., Trevino AE, Scott DA, Inoue A., Matoba S., Zhang Y., and Zhang F. Cell, 2013/09/12, Volume 154, Issue 6, p.1380-9, (2013) Read More / View Supplemental Materials
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Protein array-based profiling of CSF identifies RBPJ as an autoantigen in multiple sclerosis.Querol, L., Clark PL, Bailey MA, Cotsapas C., Cross AH, Hafler DA, Kleinstein SH, Lee JY, Yaari G., Willis SN, and O'Connor KC Neurology, 2013/09/10, Volume 81, Issue 11, p.956-963, (2013) Read More / View Supplemental Materials
Abstract
Synthesis of piperlogs and analysis of their effects on cells.Boskovic, ZV, Hussain MM, Adams DJ, Dai M., and Schreiber SL Tetrahedron, 2013/09/09, Volume 69, Issue 36, (2013) Read More / View Supplemental Materials
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Locus-specific editing of histone modifications at endogenous enhancers.Mendenhall, EM, Williamson KE, Reyon D., Zou JY, Ram O., Joung JK, and Bernstein BE Nature biotechnology, 2013/09/08, (2013) Read More / View Supplemental Materials
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Genetic evidence for recent population mixture in India.Moorjani, P., Thangaraj K., Patterson N., Lipson M., Loh PR, Govindaraj P., Berger B., Reich D., and Singh L. American journal of human genetics, 2013/09/05, Volume 93, Issue 3, p.422-38, (2013) Read More / View Supplemental Materials
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Mapping the Human Reference Genome's Missing Sequence by Three-Way Admixture in Latino Genomes.Genovese, G., Handsaker RE, Li H., Kenny EE, and McCarroll SA American journal of human genetics, 2013/09/05, Volume 93, Issue 3, p.411-21, (2013) Read More / View Supplemental Materials
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Small-molecule inhibition of inflammatory β-cell death.Lundh, M., Scully SS, Mandrup-Poulsen T., and Wagner BK Diabetes, obesity & metabolism, 2013/09/01, Volume 15 Suppl 3, p.176-84, (2013) Read More / View Supplemental Materials
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Therapeutic potential of isoform selective HDAC inhibitors for the treatment of schizophrenia.Weïwer, M., Lewis MC, Wagner FF, and Holson EB Future medicinal chemistry, 2013/09/01, Volume 5, Issue 13, p.1491-508, (2013) Read More / View Supplemental Materials
Abstract
An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.Basu, A., Bodycombe NE, Cheah JH, Price EV, Liu K., Schaefer GI, Ebright RY, Stewart ML, Ito D., Wang S., Bracha AL, Liefeld T., Wawer M., Gilbert JC, Wilson AJ, Stransky N., Kryukov GV, Dancik V., Barretina J., Garraway LA, et al. Cell, 2013/08/29, Volume 154, Issue 5, p.1151-61, (2013) Read More / View Supplemental Materials
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An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers.Roberts, SA, Lawrence MS, Klimczak LJ, Grimm SA, Fargo D., Stojanov P., Kiezun A., Kryukov GV, Carter SL, Saksena G., Harris S., Shah RR, Resnick MA, Getz G., and Gordenin DA Nature genetics, 2013/08/28, Volume 45, Issue 9, p.970-6, (2013) Read More / View Supplemental Materials
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Clonal evolution in hematological malignancies and therapeutic implications.Landau, DA, Carter SL, Getz G., and Wu CJ Leukemia, 2013/08/27, (2013) Read More / View Supplemental Materials
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Charting a dynamic DNA methylation landscape of the human genome.Ziller, MJ, Gu H., Müller F., Donaghey J., Tsai LT, Kohlbacher O., De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A., and Meissner A. Nature, 2013/08/22, Volume 500, Issue 7463, p.477-81, (2013) Read More / View Supplemental Materials
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Optical control of mammalian endogenous transcription and epigenetic states.Konermann, S., Brigham MD, Trevino AE, Hsu PD, Heidenreich M., Cong L., Platt RJ, Scott DA, Church GM, and Zhang F. Nature, 2013/08/22, Volume 500, Issue 7463, p.472-6, (2013) Read More / View Supplemental Materials
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Signatures of mutational processes in human cancer.Alexandrov, LB, Nik-Zainal S., Wedge DC, Aparicio SA, Behjati S., Biankin AV, Bignell GR, Bolli N., Borg A., Børresen-Dale AL, Boyault S., Burkhardt B., Butler AP, Caldas C., Davies HR, Desmedt C., Eils R., Eyfjörd JE, Foekens JA, Greaves M., et al. Nature, 2013/08/22, Volume 500, Issue 7463, p.415-21, (2013) Read More / View Supplemental Materials
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Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice from Salmonella Infection.Conway, KL, Kuballa P., Song JH, Patel KK, Castoreno AB, Yilmaz OH, Jijon HB, Zhang M., Aldrich LN, Villablanca EJ, Peloquin JM, Goel G., Lee IA, Mizoguchi E., Shi HN, Bhan AK, Shaw SY, Schreiber SL, Virgin HW, Shamji AF, et al. Gastroenterology, 2013/08/21, (2013) Read More / View Supplemental Materials
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Stimulating erythropoiesis in neonates.Sankaran, VG, and Agrawal PB American journal of hematology, 2013/08/20, (2013) Read More / View Supplemental Materials
Gleason Grade Progression Is Uncommon.Penney, KL, Stampfer MJ, Jahn JL, Sinnott JA, Flavin R., Rider JR, Finn S., Giovannucci E., Sesso HD, Loda M., Mucci LA, and Fiorentino M. Cancer research, 2013/08/15, Volume 73, Issue 16, p.5163-5168, (2013) Read More / View Supplemental Materials
Abstract
Two-stage microbial community experimental design.Tickle, TL, Segata N., Waldron L., Weingart U., and Huttenhower C. The ISME journal, 2013/08/15, (2013) Read More / View Supplemental Materials
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Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment.Kostic, AD, Chun E., Robertson L., Glickman JN, Gallini CA, Michaud M., Clancy TE, Chung DC, Lochhead P., Hold GL, El-Omar EM, Brenner D., Fuchs CS, Meyerson M., and Garrett WS Cell host & microbe, 2013/08/14, Volume 14, Issue 2, p.207-15, (2013) Read More / View Supplemental Materials
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In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites.Sander, JD, Ramirez CL, Linder SJ, Pattanayak V., Shoresh N., Ku M., Foden JA, Reyon D., Bernstein BE, Liu DR, and Joung JK Nucleic acids research, 2013/08/14, (2013) Read More / View Supplemental Materials
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Identification of Novel Inhibitors of Nonreplicating Mycobacterium tuberculosis Using a Carbon Starvation Model.Grant, SS, Kawate T., Nag PP, Silvis MR, Gordon K., Stanley SA, Kazyanskaya E., Nietupski R., Golas A., FitzGerald M., Cho S., Franzblau SG, and Hung DT ACS chemical biology, 2013/08/13, (2013) Read More / View Supplemental Materials
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Kinannote, a computer program to identify and classify members of the eukaryotic protein kinase superfamily.Goldberg, JM, Griggs AD, Smith JL, Haas BJ, Wortman JR, and Zeng Q. Bioinformatics (Oxford, England), 2013/08/13, (2013) Read More / View Supplemental Materials
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Concordance of gene expression in human protein complexes reveals tissue specificity and pathology.Börnigen, D., Pers TH, Thorrez L., Huttenhower C., Moreau Y., and Brunak S. Nucleic acids research, 2013/08/05, (2013) Read More / View Supplemental Materials
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De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis.Haas, BJ, Papanicolaou A., Yassour M., Grabherr M., Blood PD, Bowden J., Couger MB, Eccles D., Li B., Lieber M., Macmanes MD, Ott M., Orvis J., Pochet N., Strozzi F., Weeks N., Westerman R., William T., Dewey CN, Henschel R., et al. Nature protocols, 2013/08/01, Volume 8, Issue 8, p.1494-512, (2013) Read More / View Supplemental Materials
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Identification of small molecules for human hepatocyte expansion and iPS differentiation.Shan, J., Schwartz RE, Ross NT, Logan DJ, Thomas D., Duncan SA, North TE, Goessling W., Carpenter AE, and Bhatia SN Nature chemical biology, 2013/08/01, Volume 9, Issue 8, p.514-20, (2013) Read More / View Supplemental Materials
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Network deconvolution as a general method to distinguish direct dependencies in networks.Feizi, S., Marbach D., Médard M., and Kellis M. Nature biotechnology, 2013/08/01, Volume 31, Issue 8, p.726-33, (2013) Read More / View Supplemental Materials
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Nutrients and growth factors in mTORC1 activation.Efeyan, A., and Sabatini DM Biochemical Society transactions, 2013/08/01, Volume 41, Issue 4, p.902-5, (2013) Read More / View Supplemental Materials
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Validating therapeutic targets through human genetics.Plenge, RM, Scolnick EM, and Altshuler D. Nature reviews. Drug discovery, 2013/08/01, Volume 12, Issue 8, p.581-94, (2013) Read More / View Supplemental Materials
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Mutations in eIF4ENIF1 Are Associated With Primary Ovarian Insufficiency.Kasippillai, T., Macarthur DG, Kirby A., Thomas B., Lambalk CB, Daly M. J., and Welt CK The Journal of clinical endocrinology and metabolism, 2013/07/31, (2013) Read More / View Supplemental Materials
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High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model-based analyses of transposon-insertion sequencing data.Chao, MC, Pritchard JR, Zhang YJ, Rubin EJ, Livny J., Davis BM, and Waldor MK Nucleic acids research, 2013/07/30, (2013) Read More / View Supplemental Materials
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DNA targeting specificity of RNA-guided Cas9 nucleases.Hsu, PD, Scott DA, Weinstein JA, Ran FA, Konermann S., Agarwala V., Li Y., Fine EJ, Wu X., Shalem O., Cradick TJ, Marraffini LA, Bao G., and Zhang F. Nature biotechnology, 2013/07/21, (2013) Read More / View Supplemental Materials
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Genomics of lymphoid malignancies reveal major activation pathways in lymphocytes.Knoechel, B., and Lohr JG Journal of autoimmunity, 2013/07/20, (2013) Read More / View Supplemental Materials
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Common Variants in CLOCK Are Not Associated with Measures of Sleep Duration in People of European Ancestry from the Sleep Heart Health Study.Lane, JM, Tare A., Cade BE, Chen TH, Punjabi NM, Gottlieb DJ, Scheer FA, Redline S., and Saxena R. Biological psychiatry, 2013/07/17, (2013) Read More / View Supplemental Materials
A Microscale Human Liver Platform that Supports the Hepatic Stages of Plasmodium falciparum and vivax.March, S., Ng S., Velmurugan S., Galstian A., Shan J., Logan DJ, Carpenter AE, Thomas D., Sim BK, Mota MM, Hoffman SL, and Bhatia SN Cell host & microbe, 2013/07/17, Volume 14, Issue 1, p.104-15, (2013) Read More / View Supplemental Materials
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Genetic risk variants in African Americans with multiple sclerosis.Isobe, N., Gourraud PA, Harbo HF, Caillier SJ, Santaniello A., Khankhanian P., Maiers M., Spellman S., Cereb N., Yang S., Pando MJ, Piccio L., Cross AH, De Jager PL, Cree BA, Hauser SL, and Oksenberg JR Neurology, 2013/07/16, Volume 81, Issue 3, p.219-227, (2013) Read More / View Supplemental Materials
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Mutational heterogeneity in cancer and the search for new cancer-associated genes.Lawrence, MS, Stojanov P., Polak P., Kryukov GV, Cibulskis K., Sivachenko A., Carter SL, Stewart C., Mermel CH, Roberts SA, Kiezun A., Hammerman PS, McKenna A., Drier Y., Zou L., Ramos AH, Pugh TJ, Stransky N., Helman E., Kim J., et al. Nature, 2013/07/11, Volume 499, Issue 7457, p.214-8, (2013) Read More / View Supplemental Materials
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The Mycobacterium tuberculosis regulatory network and hypoxia.Galagan, JE, Minch K., Peterson M., Lyubetskaya A., Azizi E., Sweet L., Gomes A., Rustad T., Dolganov G., Glotova I., Abeel T., Mahwinney C., Kennedy AD, Allard R., Brabant W., Krueger A., Jaini S., Honda B., Yu WH, Hickey MJ, et al. Nature, 2013/07/11, Volume 499, Issue 7457, p.178-183, (2013) Read More / View Supplemental Materials
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Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32.Stanley, SA, Kawate T., Iwase N., Shimizu M., Clatworthy AE, Kazyanskaya E., Sacchettini JC, Ioerger TR, Siddiqi NA, Minami S., Aquadro JA, Schmidt Grant S., Rubin EJ, and Hung DT Proceedings of the National Academy of Sciences of the United States of America, 2013/07/09, Volume 110, Issue 28, p.11565-70, (2013) Read More / View Supplemental Materials
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Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma.Zhukova, N., Ramaswamy V., Remke M., Pfaff E., Shih DJ, Martin DC, Castelo-Branco P., Baskin B., Ray PN, Bouffet E., von Bueren AO, Jones DT, Northcott PA, Kool M., Sturm D., Pugh TJ, Pomeroy SL, Cho YJ, Pietsch T., Gessi M., et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013/07/08, (2013) Read More / View Supplemental Materials
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The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome.Engreitz, JM, Pandya-Jones A., McDonel P., Shishkin A., Sirokman K., Surka C., Kadri S., Xing J., Goren A., Lander E. S., Plath K., and Guttman M. Science (New York, N.Y.), 2013/07/04, (2013) Read More / View Supplemental Materials
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Browsing (Epi)genomes: A Guide to Data Resources and Epigenome Browsers for Stem Cell Researchers.Karnik, R., and Meissner A. Cell stem cell, 2013/07/03, Volume 13, Issue 1, p.14-21, (2013) Read More / View Supplemental Materials
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Ribosome Profiling Provides Evidence that Large Noncoding RNAs Do Not Encode Proteins.Guttman, M., Russell P., Ingolia NT, Weissman JS, and Lander E. S. Cell, 2013/07/03, Volume 154, Issue 1, p.240-51, (2013) Read More / View Supplemental Materials
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A Genome-wide Association Study of the Human Metabolome in a Community-Based Cohort.Rhee, EP, Ho JE, Chen MH, Shen D., Cheng S., Larson MG, Ghorbani A., Shi X., Helenius IT, O'Donnell CJ, Souza AL, Deik A., Pierce KA, Bullock K., Walford GA, Vasan RS, Florez JC, Clish C., Yeh JR, Wang TJ, et al. Cell metabolism, 2013/07/02, Volume 18, Issue 1, p.130-43, (2013) Read More / View Supplemental Materials
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Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls.McLaren, PJ, Coulonges C., Ripke S., van den Berg L., Buchbinder S., Carrington M., Cossarizza A., Dalmau J., Deeks SG, Delaneau O., De Luca A., Goedert JJ, Haas D., Herbeck JT, Kathiresan S., Kirk GD, Lambotte O., Luo M., Mallal S., van Manen D., et al. PLoS pathogens, 2013/07/01, Volume 9, Issue 7, p.e1003515, (2013) Read More / View Supplemental Materials
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CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.Bradshaw, EM, Chibnik LB, Keenan BT, Ottoboni L., Raj T., Tang A., Rosenkrantz LL, Imboywa S., Lee M., Von Korff A., Alzheimer Disease Neuroimaging Initiative, Morris MC, Evans DA, Johnson K., Sperling RA, Schneider JA, Bennett DA, and De Jager PL Nature neuroscience, 2013/07/01, Volume 16, Issue 7, p.848-50, (2013) Read More / View Supplemental Materials
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Comparative genomics as a tool to understand evolution and disease.Alföldi, J., and Lindblad-Toh K. Genome research, 2013/07/01, Volume 23, Issue 7, p.1063-8, (2013) Read More / View Supplemental Materials
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Integrated proteomic analysis of post-translational modifications by serial enrichment.Mertins, P., Qiao JW, Patel J., Udeshi ND, Clauser KR, Mani D. R., Burgess MW, Gillette MA, Jaffe JD, and Carr SA Nature methods, 2013/07/01, Volume 10, Issue 7, p.634-7, (2013) Read More / View Supplemental Materials
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Large Numbers of Genetic Variants Considered to be Pathogenic are Common in Asymptomatic Individuals.Cassa, CA, Tong MY, and Jordan DM Human mutation, 2013/07/01, (2013) Read More / View Supplemental Materials
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MetaRanker 2.0: a web server for prioritization of genetic variation data.Pers, TH, Dworzynski P., Thomas CE, Lage K., and Brunak S. Nucleic acids research, 2013/07/01, Volume 41, Issue W1, p.W104-W108, (2013) Read More / View Supplemental Materials
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Pleiotropy in complex traits: challenges and strategies.Solovieff, N., Cotsapas C., Lee PH, Purcell SM, and Smoller JW Nature reviews. Genetics, 2013/07/01, Volume 14, Issue 7, p.483-95, (2013) Read More / View Supplemental Materials
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Central Precocious Puberty Caused by Mutations in the Imprinted Gene MKRN3.Abreu, AP, Dauber A., Macedo DB, Noel SD, Brito VN, Gill JC, Cukier P., Thompson IR, Navarro VM, Gagliardi PC, Rodrigues T., Kochi C., Longui CA, Beckers D., de Zegher F., Montenegro LR, Mendonca BB, Carroll RS, Hirschhorn JN, Latronico AC, et al. The New England journal of medicine, 2013/06/27, Volume 368, Issue 26, p.2467-2475, (2013) Read More / View Supplemental Materials
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Circumferential or sectored beam arrangements for stereotactic body radiation therapy (SBRT) of primary lung tumors: Effect on target and normal-structure dose-volume metrics.Rosenberg, MW, Kato CM, Carson KM, Matsunaga NM, Arao RF, Doss EJ, McCracken CL, Meng LZ, Chen Y., Laub WU, Fuss M., and Tanyi JA Medical dosimetry : official journal of the American Association of Medical Dosimetrists, 2013/06/27, (2013) Read More / View Supplemental Materials
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Gossypol and an HMT G9a inhibitor act in synergy to induce cell death in pancreatic cancer cells.Yuan, Y., Tang AJ, Castoreno AB, Kuo SY, Wang Q., Kuballa P., Xavier R., Shamji AF, Schreiber SL, and Wagner BK Cell death & disease, 2013/06/27, Volume 4, p.e690, (2013) Read More / View Supplemental Materials
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Comprehensive molecular characterization of clear cell renal cell carcinoma.The Cancer Genome Atlas Research, Network, Analysis working group: Baylor College of Medicine, Creighton CJ, Morgan M., Gunaratne PH, Wheeler DA, Gibbs RA, BC Cancer Agency, Gordon Robertson A., Chu A., Broad Institute, Beroukhim R., Cibulskis K., Brigham & Women’s Hospital, Signoretti S., Brown University, Vandin Hsin-Ta Wu F., Raphael BJ, The University of Texas MD Anderson Cancer Center, Verhaak RG, et al. Nature, 2013/06/23, (2013) Read More / View Supplemental Materials
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Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma.Liao, RG, Jung J., Tchaicha JH, Wilkerson MD, Sivachenko A., Beauchamp EM, Pugh TJ, Pedamallu CS, Hayes DN, Gray NS, Getz G., Wong KK, Meyerson M., and Hammerman PS Cancer research, 2013/06/20, (2013) Read More / View Supplemental Materials
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Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas.Wang, P., Dong Q., Zhang C., Kuan PF, Liu Y., Jeck WR, Andersen JB, Jiang W., Savich GL, Tan TX, Auman JT, Hoskins JM, Misher AD, Moser CD, Yourstone SM, Kim JW, Cibulskis K., Getz G., Hunt HV, Thorgeirsson SS, et al. Oncogene, 2013/06/20, Volume 32, Issue 25, p.3091-100, (2013) Read More / View Supplemental Materials
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Discovery of the first histone deacetylase 6/8 dual inhibitors.Olson, DE, Wagner FF, Kaya T., Gale JP, Aidoud N., Davoine EL, Lazzaro F., Weïwer M., Zhang YL, and Holson EB Journal of medicinal chemistry, 2013/06/13, Volume 56, Issue 11, p.4816-20, (2013) Read More / View Supplemental Materials
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Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells.Shalek, AK, Satija R., Adiconis X., Gertner RS, Gaublomme JT, Raychowdhury R., Schwartz S., Yosef N., Malboeuf C., Lu D., Trombetta JJ, Gennert D., Gnirke A., Goren A., Hacohen N., Levin JZ, Park H., and Regev A. Nature, 2013/06/13, Volume 498, Issue 7453, p.236-40, (2013) Read More / View Supplemental Materials
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Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers.Hagerstrand, D., Tong A., Schumacher SE, Ilic N., Shen RR, Cheung HW, Vazquez F., Shrestha Y., Kim SY, Rosenbluh J., Schinzel AC, Barbie DA, Mermel CH, Weir BA, Garraway LA, Tamayo P., Mesirov J. P., Beroukhim R., and Hahn WC Cancer discovery, 2013/06/13, (2013) Read More / View Supplemental Materials
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The Genome of Anopheles darlingi, the main neotropical malaria vector.Marinotti, O., Cerqueira GC, de Almeida LG, Ferro MI, Loreto EL, Zaha A., Teixeira SM, Wespiser AR, Almeida E Silva A., Schlindwein AD, Pacheco AC, da Silva AL, Graveley BR, Walenz BP, de Araujo Lima B., Ribeiro CA, Nunes-Silva CG, de Carvalho CR, de Almeida Soares CM, de Menezes CB, et al. Nucleic acids research, 2013/06/12, (2013) Read More / View Supplemental Materials
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Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system.Bikard, D., Jiang W., Samai P., Hochschild A., Zhang F., and Marraffini LA Nucleic acids research, 2013/06/12, (2013) Read More / View Supplemental Materials
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In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling.Miller, PG, Al-Shahrour F., Hartwell KA, Chu LP, Järås M., Puissant A., McConkey ME, Cowley GS, Shterental S., Alexe G., Armstrong SA, Root DE, Scadden DT, Hynes R. O., Mukherjee S., Stegmaier K., and Ebert BL Cancer cell, 2013/06/11, (2013) Read More / View Supplemental Materials
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Hopping between Differentiation States in Lung Adenocarcinoma.Watanabe, H., and Meyerson M. Cancer cell, 2013/06/10, Volume 23, Issue 6, p.707-9, (2013) Read More / View Supplemental Materials
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miR-155 in Acute Myeloid Leukemia: Not Merely a Prognostic Marker?Joyce, CE, and Novina CD Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013/06/10, Volume 31, Issue 17, p.2219-21, (2013) Read More / View Supplemental Materials
ATHLATES: accurate typing of human leukocyte antigen through exome sequencing.Liu, C., Yang X., Duffy B., Mohanakumar T., Mitra RD, Zody MC, and Pfeifer JD Nucleic acids research, 2013/06/08, (2013) Read More / View Supplemental Materials
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Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides.Gerard, B., Lee MD 4th, Dandapani S., Duvall JR, Fitzgerald ME, Kesavan S., Lowe JT, Marié JC, Pandya BA, Suh BC, O'Shea MW, Dombrowski M., Hamann D., Lemercier B., Murillo T., Akella LB, Foley MA, and Marcaurelle LA The Journal of organic chemistry, 2013/06/07, Volume 78, Issue 11, p.5160-71, (2013) Read More / View Supplemental Materials
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C-RAF mutations confer resistance to RAF inhibitors.Antony, R., Emery CM, Sawyer AM, and Garraway LA Cancer research, 2013/06/04, (2013) Read More / View Supplemental Materials
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RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer.Serra, V., Eichhorn PJ, García-García C., Ibrahim YH, Prudkin L., Sánchez G., Rodríguez O., Antón P., Parra JL, Marlow S., Hahn WC, Kim SY, and Baselga J. The Journal of clinical investigation, 2013/06/03, Volume 123, Issue 6, p.2551-63, (2013) Read More / View Supplemental Materials
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Arboretum: Reconstruction and analysis of the evolutionary history of condition-specific transcriptional modules.Roy, S., Wapinski I., Pfiffner J., French C., Socha A., Konieczka J., Habib N., Kellis M., Thompson D., and Regev A. Genome research, 2013/06/01, Volume 23, Issue 6, p.1039-50, (2013) Read More / View Supplemental Materials
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Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.Hett, EC, Slater LH, Mark KG, Kawate T., Monks BG, Stutz A., Latz E., and Hung DT Nature chemical biology, 2013/06/01, Volume 9, Issue 6, p.398-405, (2013) Read More / View Supplemental Materials
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Distinctive Expansion of Potential Virulence Genes in the Genome of the Oomycete Fish Pathogen Saprolegnia parasitica.Jiang, RH, de Bruijn I., Haas BJ, Belmonte R., Löbach L., Christie J., van den Ackerveken G., Bottin A., Bulone V., Díaz-Moreno SM, Dumas B., Fan L., Gaulin E., Govers F., Grenville-Briggs LJ, Horner NR, Levin JZ, Mammella M., Meijer HJ, Morris P., et al. PLoS genetics, 2013/06/01, Volume 9, Issue 6, p.e1003272, (2013) Read More / View Supplemental Materials
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An aberrant transcription factor network essential for wnt signaling and stem cell maintenance in glioblastoma.Rheinbay, E., Suvà ML, Gillespie SM, Wakimoto H., Patel AP, Shahid M., Oksuz O., Rabkin SD, Martuza RL, Rivera MN, Louis DN, Kasif S., Chi AS, and Bernstein BE Cell reports, 2013/05/30, Volume 3, Issue 5, p.1567-79, (2013) Read More / View Supplemental Materials
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A Novel APOB Mutation Identified by Exome Sequencing Cosegregates With Steatosis, Liver Cancer, and Hypocholesterolemia.Cefalù, AB, Pirruccello JP, Noto D., Gabriel S., Valenti V., Gupta N., Spina R., Tarugi P., Kathiresan S., and Averna MR Arteriosclerosis, thrombosis, and vascular biology, 2013/05/30, (2013) Read More / View Supplemental Materials
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Genome sequencing sheds light on emerging drug resistance in malaria parasites.Neafsey, DE Nature genetics, 2013/05/29, Volume 45, Issue 6, p.589-90, (2013) Read More / View Supplemental Materials
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The Genotype-Tissue Expression (GTEx) project.Lonsdale, J., Thomas J., Salvatore M., Phillips R., Lo E., Shad S., Hasz R., Walters G., Garcia F., Young N., Foster B., Moser M., Karasik E., Gillard B., Ramsey K., Sullivan S., Bridge J., Magazine H., Syron J., Fleming J., et al. Nature genetics, 2013/05/29, Volume 45, Issue 6, p.580-5, (2013) Read More / View Supplemental Materials
Selective HDAC1/HDAC2 Inhibitors Induce Neuroblastoma Differentiation.Frumm, SM, Fan ZP, Ross KN, Duvall JR, Gupta S., VerPlank L., Suh BC, Holson E., Wagner FF, Smith WB, Paranal RM, Bassil CF, Qi J., Roti G., Kung AL, Bradner JE, Tolliday N., and Stegmaier K. Chemistry & biology, 2013/05/23, Volume 20, Issue 5, p.713-25, (2013) Read More / View Supplemental Materials
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Small-Molecule Inhibitors of Cytokine-Mediated STAT1 Signal Transduction in β-Cells with Improved Aqueous Solubility.Scully, SS, Tang AJ, Lundh M., Mosher CM, Perkins KM, and Wagner BK Journal of medicinal chemistry, 2013/05/23, Volume 56, Issue 10, p.4125-9, (2013) Read More / View Supplemental Materials
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Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells.Gifford, CA, Ziller MJ, Gu H., Trapnell C., Donaghey J., Tsankov A., Shalek AK, Kelley DR, Shishkin AA, Issner R., Zhang X., Coyne M., Fostel JL, Holmes L., Meldrim J., Guttman M., Epstein C., Park H., Kohlbacher O., Rinn J., et al. Cell, 2013/05/23, Volume 153, Issue 5, p.1149-63, (2013) Read More / View Supplemental Materials
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A Dietary Regimen of Caloric Restriction or Pharmacological Activation of SIRT1 to Delay the Onset of Neurodegeneration.Gräff, J., Kahn M., Samiei A., Gao J., Ota KT, Rei D., and Tsai LH The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013/05/22, Volume 33, Issue 21, p.8951-60, (2013) Read More / View Supplemental Materials
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RhoGTPases - NODes for effector-triggered immunity in animals.Stuart, LM, and Boyer L. Cell research, 2013/05/21, (2013) Read More / View Supplemental Materials
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Design, Implementation, and Multi-Site Evaluation of a System Suitability Protocol for the Quantitative Assessment of Instrument Performance in LC-MRM-MS.Abbatiello, SE, Mani D. R., Schilling B., Maclean B., Zimmerman LJ, Feng X., Cusack MP, Sedransk N., Hall SC, Addona T., Allen S., Dodder NG, Ghosh M., Held JM, Hedrick V., Inerowicz HD, Jackson A., Keshishian H., Kim JW, Lyssand JS, et al. Molecular & cellular proteomics : MCP, 2013/05/20, (2013) Read More / View Supplemental Materials
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Comparative analysis of RNA sequencing methods for degraded or low-input samples.Adiconis, X., Borges-Rivera D., Satija R., Deluca DS, Busby MA, Berlin AM, Sivachenko A., Thompson DA, Wysoker A., Fennell T., Gnirke A., Pochet N., Regev A., and Levin JZ Nature methods, 2013/05/19, (2013) Read More / View Supplemental Materials
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Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1.Ramkissoon, LA, Horowitz PM, Craig JM, Ramkissoon SH, Rich BE, Schumacher SE, McKenna A., Lawrence MS, Bergthold G., Brastianos PK, Tabak B., Ducar MD, Van Hummelen P., Macconaill LE, Pouissant-Young T., Cho YJ, Taha H., Mahmoud M., Bowers DC, Margraf L., et al. Proceedings of the National Academy of Sciences of the United States of America, 2013/05/14, Volume 110, Issue 20, p.8188-93, (2013) Read More / View Supplemental Materials
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Entering the age of whole-exome sequencing in rheumatic diseases: Novel insights into disease pathogenicity.Okada, Y., and Plenge RM Arthritis and rheumatism, 2013/05/10, (2013) Read More / View Supplemental Materials
Targeted exome sequencing of suspected mitochondrial disorders.Lieber, DS, Calvo SE, Shanahan K., Slate NG, Liu S., Hershman SG, Gold NB, Chapman BA, Thorburn DR, Berry GT, Schmahmann JD, Borowsky ML, Mueller DM, Sims KB, and Mootha VK Neurology, 2013/05/07, Volume 80, Issue 19, p.1762-1770, (2013) Read More / View Supplemental Materials
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Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive.Lamming, DW, Ye L., Astle CM, Baur JA, Sabatini DM, and Harrison DE Aging cell, 2013/05/04, (2013) Read More / View Supplemental Materials
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Integrated genomic characterization of endometrial carcinoma.Cancer Genome Atlas Research, Network, Genome sequencing centres: Broad Institute, Getz G., Gabriel SB, Cibulskis K., Lander E., Sivachenko A., Sougnez C., Lawrence M., Washington University in St Louis, Kandoth C., Dooling D., Fulton R., Fulton L., Kalicki-Veizer J., McLellan MD, O'Laughlin M., Schmidt H., Wilson RK, Ye K., et al. Nature, 2013/05/02, Volume 497, Issue 7447, p.67-73, (2013) Read More / View Supplemental Materials
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