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2013
In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling.Miller, PG, Al-Shahrour F., Hartwell KA, Chu LP, Järås M., Puissant A., McConkey ME, Cowley GS, Shterental S., Alexe G., Armstrong SA, Root DE, Scadden DT, Hynes R. O., Mukherjee S., Stegmaier K., and Ebert BL Cancer cell, 2013/06/11, (2013) Read More / View Supplemental Materials
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Hopping between Differentiation States in Lung Adenocarcinoma.Watanabe, H., and Meyerson M. Cancer cell, 2013/06/10, Volume 23, Issue 6, p.707-9, (2013) Read More / View Supplemental Materials
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miR-155 in Acute Myeloid Leukemia: Not Merely a Prognostic Marker?Joyce, CE, and Novina CD Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013/06/10, Volume 31, Issue 17, p.2219-21, (2013) Read More / View Supplemental Materials
ATHLATES: accurate typing of human leukocyte antigen through exome sequencing.Liu, C., Yang X., Duffy B., Mohanakumar T., Mitra RD, Zody MC, and Pfeifer JD Nucleic acids research, 2013/06/08, (2013) Read More / View Supplemental Materials
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Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides.Gerard, B., Lee MD 4th, Dandapani S., Duvall JR, Fitzgerald ME, Kesavan S., Lowe JT, Marié JC, Pandya BA, Suh BC, O'Shea MW, Dombrowski M., Hamann D., Lemercier B., Murillo T., Akella LB, Foley MA, and Marcaurelle LA The Journal of organic chemistry, 2013/06/07, Volume 78, Issue 11, p.5160-71, (2013) Read More / View Supplemental Materials
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C-RAF mutations confer resistance to RAF inhibitors.Antony, R., Emery CM, Sawyer AM, and Garraway LA Cancer research, 2013/06/04, (2013) Read More / View Supplemental Materials
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RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer.Serra, V., Eichhorn PJ, García-García C., Ibrahim YH, Prudkin L., Sánchez G., Rodríguez O., Antón P., Parra JL, Marlow S., Hahn WC, Kim SY, and Baselga J. The Journal of clinical investigation, 2013/06/03, Volume 123, Issue 6, p.2551-63, (2013) Read More / View Supplemental Materials
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Arboretum: Reconstruction and analysis of the evolutionary history of condition-specific transcriptional modules.Roy, S., Wapinski I., Pfiffner J., French C., Socha A., Konieczka J., Habib N., Kellis M., Thompson D., and Regev A. Genome research, 2013/06/01, Volume 23, Issue 6, p.1039-50, (2013) Read More / View Supplemental Materials
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Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.Hett, EC, Slater LH, Mark KG, Kawate T., Monks BG, Stutz A., Latz E., and Hung DT Nature chemical biology, 2013/06/01, Volume 9, Issue 6, p.398-405, (2013) Read More / View Supplemental Materials
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Distinctive Expansion of Potential Virulence Genes in the Genome of the Oomycete Fish Pathogen Saprolegnia parasitica.Jiang, RH, de Bruijn I., Haas BJ, Belmonte R., Löbach L., Christie J., van den Ackerveken G., Bottin A., Bulone V., Díaz-Moreno SM, Dumas B., Fan L., Gaulin E., Govers F., Grenville-Briggs LJ, Horner NR, Levin JZ, Mammella M., Meijer HJ, Morris P., et al. PLoS genetics, 2013/06/01, Volume 9, Issue 6, p.e1003272, (2013) Read More / View Supplemental Materials
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An aberrant transcription factor network essential for wnt signaling and stem cell maintenance in glioblastoma.Rheinbay, E., Suvà ML, Gillespie SM, Wakimoto H., Patel AP, Shahid M., Oksuz O., Rabkin SD, Martuza RL, Rivera MN, Louis DN, Kasif S., Chi AS, and Bernstein BE Cell reports, 2013/05/30, Volume 3, Issue 5, p.1567-79, (2013) Read More / View Supplemental Materials
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A Novel APOB Mutation Identified by Exome Sequencing Cosegregates With Steatosis, Liver Cancer, and Hypocholesterolemia.Cefalù, AB, Pirruccello JP, Noto D., Gabriel S., Valenti V., Gupta N., Spina R., Tarugi P., Kathiresan S., and Averna MR Arteriosclerosis, thrombosis, and vascular biology, 2013/05/30, (2013) Read More / View Supplemental Materials
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Genome sequencing sheds light on emerging drug resistance in malaria parasites.Neafsey, DE Nature genetics, 2013/05/29, Volume 45, Issue 6, p.589-90, (2013) Read More / View Supplemental Materials
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The Genotype-Tissue Expression (GTEx) project.Lonsdale, J., Thomas J., Salvatore M., Phillips R., Lo E., Shad S., Hasz R., Walters G., Garcia F., Young N., Foster B., Moser M., Karasik E., Gillard B., Ramsey K., Sullivan S., Bridge J., Magazine H., Syron J., Fleming J., et al. Nature genetics, 2013/05/29, Volume 45, Issue 6, p.580-5, (2013) Read More / View Supplemental Materials
Selective HDAC1/HDAC2 Inhibitors Induce Neuroblastoma Differentiation.Frumm, SM, Fan ZP, Ross KN, Duvall JR, Gupta S., VerPlank L., Suh BC, Holson E., Wagner FF, Smith WB, Paranal RM, Bassil CF, Qi J., Roti G., Kung AL, Bradner JE, Tolliday N., and Stegmaier K. Chemistry & biology, 2013/05/23, Volume 20, Issue 5, p.713-25, (2013) Read More / View Supplemental Materials
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Small-Molecule Inhibitors of Cytokine-Mediated STAT1 Signal Transduction in β-Cells with Improved Aqueous Solubility.Scully, SS, Tang AJ, Lundh M., Mosher CM, Perkins KM, and Wagner BK Journal of medicinal chemistry, 2013/05/23, Volume 56, Issue 10, p.4125-9, (2013) Read More / View Supplemental Materials
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Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells.Gifford, CA, Ziller MJ, Gu H., Trapnell C., Donaghey J., Tsankov A., Shalek AK, Kelley DR, Shishkin AA, Issner R., Zhang X., Coyne M., Fostel JL, Holmes L., Meldrim J., Guttman M., Epstein C., Park H., Kohlbacher O., Rinn J., et al. Cell, 2013/05/23, Volume 153, Issue 5, p.1149-63, (2013) Read More / View Supplemental Materials
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A Dietary Regimen of Caloric Restriction or Pharmacological Activation of SIRT1 to Delay the Onset of Neurodegeneration.Gräff, J., Kahn M., Samiei A., Gao J., Ota KT, Rei D., and Tsai LH The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013/05/22, Volume 33, Issue 21, p.8951-60, (2013) Read More / View Supplemental Materials
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RhoGTPases - NODes for effector-triggered immunity in animals.Stuart, LM, and Boyer L. Cell research, 2013/05/21, (2013) Read More / View Supplemental Materials
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Design, Implementation, and Multi-Site Evaluation of a System Suitability Protocol for the Quantitative Assessment of Instrument Performance in LC-MRM-MS.Abbatiello, SE, Mani D. R., Schilling B., Maclean B., Zimmerman LJ, Feng X., Cusack MP, Sedransk N., Hall SC, Addona T., Allen S., Dodder NG, Ghosh M., Held JM, Hedrick V., Inerowicz HD, Jackson A., Keshishian H., Kim JW, Lyssand JS, et al. Molecular & cellular proteomics : MCP, 2013/05/20, (2013) Read More / View Supplemental Materials
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Comparative analysis of RNA sequencing methods for degraded or low-input samples.Adiconis, X., Borges-Rivera D., Satija R., Deluca DS, Busby MA, Berlin AM, Sivachenko A., Thompson DA, Wysoker A., Fennell T., Gnirke A., Pochet N., Regev A., and Levin JZ Nature methods, 2013/05/19, (2013) Read More / View Supplemental Materials
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Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1.Ramkissoon, LA, Horowitz PM, Craig JM, Ramkissoon SH, Rich BE, Schumacher SE, McKenna A., Lawrence MS, Bergthold G., Brastianos PK, Tabak B., Ducar MD, Van Hummelen P., Macconaill LE, Pouissant-Young T., Cho YJ, Taha H., Mahmoud M., Bowers DC, Margraf L., et al. Proceedings of the National Academy of Sciences of the United States of America, 2013/05/14, Volume 110, Issue 20, p.8188-93, (2013) Read More / View Supplemental Materials
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Entering the age of whole-exome sequencing in rheumatic diseases: Novel insights into disease pathogenicity.Okada, Y., and Plenge RM Arthritis and rheumatism, 2013/05/10, (2013) Read More / View Supplemental Materials
Targeted exome sequencing of suspected mitochondrial disorders.Lieber, DS, Calvo SE, Shanahan K., Slate NG, Liu S., Hershman SG, Gold NB, Chapman BA, Thorburn DR, Berry GT, Schmahmann JD, Borowsky ML, Mueller DM, Sims KB, and Mootha VK Neurology, 2013/05/07, Volume 80, Issue 19, p.1762-1770, (2013) Read More / View Supplemental Materials
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Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive.Lamming, DW, Ye L., Astle CM, Baur JA, Sabatini DM, and Harrison DE Aging cell, 2013/05/04, (2013) Read More / View Supplemental Materials
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Integrated genomic characterization of endometrial carcinoma.Cancer Genome Atlas Research, Network, Genome sequencing centres: Broad Institute, Getz G., Gabriel SB, Cibulskis K., Lander E., Sivachenko A., Sougnez C., Lawrence M., Washington University in St Louis, Kandoth C., Dooling D., Fulton R., Fulton L., Kalicki-Veizer J., McLellan MD, O'Laughlin M., Schmidt H., Wilson RK, Ye K., et al. Nature, 2013/05/02, Volume 497, Issue 7447, p.67-73, (2013) Read More / View Supplemental Materials
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Multiple Inflammatory Biomarkers in Relation to Cardiovascular Events and Mortality in the Community.Schnabel, RB, Yin X., Larson MG, Yamamoto JF, Fontes JD, Kathiresan S., Rong J., Levy D., Keaney JF Jr, Wang TJ, Murabito JM, Vasan RS, and Benjamin EJ Arteriosclerosis, thrombosis, and vascular biology, 2013/05/02, (2013) Read More / View Supplemental Materials
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Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia.The Cancer Genome Atlas Research, Network The New England journal of medicine, 2013/05/01, (2013) Read More / View Supplemental Materials
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High-Throughput Tyrosine Kinase Activity Profiling Identifies FAK as a Candidate Therapeutic Target in Ewing Sarcoma.Crompton, BD, Carlton AL, Thorner AR, Christie AL, Du J., Calicchio ML, Rivera MN, Fleming MD, Kohl NE, Kung AL, and Stegmaier K. Cancer research, 2013/05/01, Volume 73, Issue 9, p.2873-83, (2013) Read More / View Supplemental Materials
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Improved ancestry inference using weights from external reference panels.Chen, CY, Pollack S., Hunter DJ, Hirschhorn JN, Kraft P., and Price AL Bioinformatics (Oxford, England), 2013/04/30, (2013) Read More / View Supplemental Materials
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From genetics of inflammatory bowel disease towards mechanistic insights.Graham, DB, and Xavier RJ Trends in immunology, 2013/04/29, (2013) Read More / View Supplemental Materials
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Immunological Genome Project and systems immunology.Shay, T., and Kang J. Trends in immunology, 2013/04/27, (2013) Read More / View Supplemental Materials
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Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge.Plenge, RM, Greenberg JD, Mangravite LM, Derry JM, Stahl EA, Coenen MJ, Barton A., Padyukov L., Klareskog L., Gregersen PK, Mariette X., Moreland LW, Bridges SL Jr, de Vries N., Huizinga TW, Guchelaar HJ, International Rheumatoid Arthritis Consortium(INTERACT), Friend SH, and Stolovitzky G. Nature genetics, 2013/04/26, Volume 45, Issue 5, p.468-9, (2013) Read More / View Supplemental Materials
Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.Dulak, AM, Stojanov P., Peng S., Lawrence MS, Fox C., Stewart C., Bandla S., Imamura Y., Schumacher SE, Shefler E., McKenna A., Carter SL, Cibulskis K., Sivachenko A., Saksena G., Voet D., Ramos AH, Auclair D., Thompson K., Sougnez C., et al. Nature genetics, 2013/04/26, Volume 45, Issue 5, p.478-86, (2013) Read More / View Supplemental Materials
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Genomics of Loa loa, a Wolbachia-free filarial parasite of humans.Desjardins, CA, Cerqueira GC, Goldberg JM, Dunning Hotopp JC, Haas BJ, Zucker J., Ribeiro JM, Saif S., Levin JZ, Fan L., Zeng Q., Russ C., Wortman JR, Fink DL, Birren BW, and Nutman TB Nature genetics, 2013/04/26, Volume 45, Issue 5, p.495-500, (2013) Read More / View Supplemental Materials
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Punctuated evolution of prostate cancer genomes.Baca, SC, Prandi D., Lawrence MS, Mosquera JM, Romanel A., Drier Y., Park K., Kitabayashi N., MacDonald TY, Ghandi M., Van Allen E., Kryukov GV, Sboner A., Theurillat JP, Soong TD, Nickerson E., Auclair D., Tewari A., Beltran H., Onofrio RC, et al. Cell, 2013/04/25, Volume 153, Issue 3, p.666-77, (2013) Read More / View Supplemental Materials
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DEVELOPMENTAL TIMING OF CHILD MALTREATMENT AND SYMPTOMS OF DEPRESSION AND SUICIDAL IDEATION IN YOUNG ADULTHOOD: RESULTS FROM THE NATIONAL LONGITUDINAL STUDY OF ADOLESCENT HEALTH.Dunn, EC, McLaughlin KA, Slopen N., Rosand J., and Smoller JW Depression and anxiety, 2013/04/16, (2013) Read More / View Supplemental Materials
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DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1.Soda, T., Frank C., Ishizuka K., Baccarella A., Park YU, Flood Z., Park SK, Sawa A., and Tsai LH Molecular psychiatry, 2013/04/16, (2013) Read More / View Supplemental Materials
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Clinical Analysis and Interpretation of Cancer Genome Data.Van Allen, EM, Wagle N., and Levy MA Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013/04/15, (2013) Read More / View Supplemental Materials
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Genomics-Driven Oncology: Framework for an Emerging Paradigm.Garraway, LA Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013/04/15, (2013) Read More / View Supplemental Materials
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Precision Oncology: An Overview.Garraway, LA, Verwey J., and Ballman K. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013/04/15, (2013) Read More / View Supplemental Materials
An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries.Mulrooney, CA, Lahr DL, Quintin MJ, Youngsaye W., Moccia D., Asiedu JK, Mulligan EL, Akella LB, Marcaurelle LA, Montgomery P., Bittker JA, Clemons PA, Brudz S., Dandapani S., Duvall JR, Tolliday NJ, and De Souza A. Journal of computer-aided molecular design, 2013/04/13, (2013) Read More / View Supplemental Materials
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Persistent bacterial infections, antibiotic tolerance, and the oxidative stress response.Grant, SS, and Hung DT Virulence, 2013/04/05, Volume 4, Issue 4, (2013) Read More / View Supplemental Materials
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Common risk alleles for inflammatory diseases are targets of recent positive selection.Raj, T., Kuchroo M., Replogle JM, Raychaudhuri S., Stranger BE, and De Jager PL American journal of human genetics, 2013/04/04, Volume 92, Issue 4, p.517-29, (2013) Read More / View Supplemental Materials
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Antidepressant response and polygenes.Purcell, SM Biological psychiatry, 2013/04/01, Volume 73, Issue 7, p.600-1, (2013) Read More / View Supplemental Materials
Commentary: Can maternal-paternal comparisons contribute to our understanding of maternal pre-pregnancy obesity and its association with offspring cognitive outcomes?Brion, MJ International journal of epidemiology, 2013/04/01, Volume 42, Issue 2, p.518-9, (2013) Read More / View Supplemental Materials
Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli.Gat-Viks, I., Chevrier N., Wilentzik R., Eisenhaure T., Raychowdhury R., Steuerman Y., Shalek AK, Hacohen N., Amit I., and Regev A. Nature biotechnology, 2013/04/01, Volume 31, Issue 4, p.342-9, (2013) Read More / View Supplemental Materials
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Response to sul and eskin.Price, AL, Zaitlen NA, Reich D., and Patterson N. Nature reviews. Genetics, 2013/04/01, Volume 14, Issue 4, p.300, (2013) Read More / View Supplemental Materials
Target identification and mechanism of action in chemical biology and drug discovery.Schenone, M., Dančík V., Wagner BK, and Clemons PA Nature chemical biology, 2013/04/01, Volume 9, Issue 4, p.232-40, (2013) Read More / View Supplemental Materials
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IKKε-Mediated Tumorigenesis Requires K63-Linked Polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 Ubiquitin Ligase Complex.Zhou, AY, Shen RR, Kim E., Lock YJ, Xu M., Chen ZJ, and Hahn WC Cell reports, 2013/03/28, Volume 3, Issue 3, p.724-33, (2013) Read More / View Supplemental Materials
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Lessons from the cancer genome.Garraway, LA, and Lander E. S. Cell, 2013/03/28, Volume 153, Issue 1, p.17-37, (2013) Read More / View Supplemental Materials
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Structure and Ubiquitination-Dependent Activation of TANK-Binding Kinase 1.Tu, D., Zhu Z., Zhou AY, Yun CH, Lee KE, Toms AV, Li Y., Dunn GP, Chan E., Thai T., Yang S., Ficarro SB, Marto JA, Jeon H., Hahn WC, Barbie DA, and Eck MJ Cell reports, 2013/03/28, Volume 3, Issue 3, p.747-58, (2013) Read More / View Supplemental Materials
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Discovery of Small-Molecule Enhancers of Reactive Oxygen Species That are Nontoxic or Cause Genotype-Selective Cell Death.Adams, DJ, Boskovic ZV, Theriault JR, Wang AJ, Stern AM, Wagner BK, Shamji AF, and Schreiber SL ACS chemical biology, 2013/03/25, (2013) Read More / View Supplemental Materials
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Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.Germain, AR, Carmody LC, Nag PP, Morgan B., VerPlank L., Fernandez C., Donckele E., Feng Y., Perez JR, Dandapani S., Palmer M., Lander E. S., Gupta PB, Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2013/03/15, Volume 23, Issue 6, p.1834-8, (2013) Read More / View Supplemental Materials
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Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging.Rhee, HW, Zou P., Udeshi ND, Martell JD, Mootha VK, Carr SA, and Ting AY Science (New York, N.Y.), 2013/03/15, Volume 339, Issue 6125, p.1328-31, (2013) Read More / View Supplemental Materials
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Selective access to trisubstituted macrocyclic e- and z-alkenes from the ring-closing metathesis of vinylsiloxanes.Wang, Y., Jimenez M., Sheehan P., Zhong C., Hung AW, Tam CP, and Young DW Organic letters, 2013/03/15, Volume 15, Issue 6, p.1218-21, (2013) Read More / View Supplemental Materials
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Estimating selection on synonymous codon usage from noisy experimental data.Wallace, EW, Airoldi EM, and Drummond DA Molecular biology and evolution, 2013/03/14, (2013) Read More / View Supplemental Materials
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Nozzle: a report generation toolkit for data analysis pipelines.Gehlenborg, N., Noble MS, Getz G., Chin L., and Park PJ Bioinformatics (Oxford, England), 2013/03/11, (2013) Read More / View Supplemental Materials
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Genome-wide association studies of hematologic phenotypes: a window into human hematopoiesis.Sankaran, VG, and Orkin SH Current opinion in genetics & development, 2013/03/07, (2013) Read More / View Supplemental Materials
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An Inflammatory Situation: SOX2 and STAT3 Cooperate in Squamous Cell Carcinoma Initiation.Bass, AJ, and Wang TC Cell stem cell, 2013/03/07, Volume 12, Issue 3, p.266-8, (2013) Read More / View Supplemental Materials
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Dynamic regulatory network controlling TH17 cell differentiation.Yosef, N., Shalek AK, Gaublomme JT, Jin H., Lee Y., Awasthi A., Wu C., Karwacz K., Xiao S., Jorgolli M., Gennert D., Satija R., Shakya A., Lu DY, Trombetta JJ, Pillai MR, Ratcliffe PJ, Coleman ML, Bix M., Tantin D., et al. Nature, 2013/03/06, (2013) Read More / View Supplemental Materials
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Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1.Wu, C., Yosef N., Thalhamer T., Zhu C., Xiao S., Kishi Y., Regev A., and Kuchroo VK Nature, 2013/03/06, (2013) Read More / View Supplemental Materials
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Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells.Kleinewietfeld, M., Manzel A., Titze J., Kvakan H., Yosef N., Linker RA, Muller DN, and Hafler DA Nature, 2013/03/06, (2013) Read More / View Supplemental Materials
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Effector-triggered versus pattern-triggered immunity: how animals sense pathogens.Stuart, LM, Paquette N., and Boyer L. Nature reviews. Immunology, 2013/03/01, Volume 13, Issue 3, p.199-206, (2013) Read More / View Supplemental Materials
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Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing.Kirby, A., Gnirke A., Jaffe DB, Barešová V., Pochet N., Blumenstiel B., Ye C., Aird D., Stevens C., Robinson JT, Cabili MN, Gat-Viks I., Kelliher E., Daza R., DeFelice M., Hůlková H., Sovová J., Vylet'al P., Antignac C., Guttman M., et al. Nature genetics, 2013/03/01, Volume 45, Issue 3, p.299-303, (2013) Read More / View Supplemental Materials
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Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition.Puissant, A., Frumm SM, Alexe G., Bassil CF, Qi J., Chanthery YH, Nekritz EA, Zeid R., Gustafson WC, Greninger P., Garnett MJ, McDermott U., Benes CH, Kung AL, Weiss WA, Bradner JE, and Stegmaier K. Cancer discovery, 2013/03/01, Volume 3, Issue 3, p.308-323, (2013) Read More / View Supplemental Materials
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Identification of Nonvisual Photomotor Response Cells in the Vertebrate Hindbrain.Kokel, D., Dunn TW, Ahrens MB, Alshut R., Cheung CY, Saint-Amant L., Bruni G., Mateus R., van Ham TJ, Shiraki T., Fukada Y., Kojima D., Yeh JR, Mikut R., von Lintig J., Engert F., and Peterson RT The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013/02/27, Volume 33, Issue 9, p.3834-3843, (2013) Read More / View Supplemental Materials
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Using population admixture to help complete maps of the human genome.Genovese, G., Handsaker RE, Li H., Altemose N., Lindgren AM, Chambert K., Pasaniuc B., Price AL, Reich D., Morton CC, Pollak MR, Wilson JG, and McCarroll SA Nature genetics, 2013/02/24, (2013) Read More / View Supplemental Materials
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Conservation and divergence in the transcriptional programs of the human and mouse immune systems.Shay, T., Jojic V., Zuk O., Rothamel K., Puyraimond-Zemmour D., Feng T., Wakamatsu E., Benoist C., Koller D., Regev A., and ImmGen Consortium Proceedings of the National Academy of Sciences of the United States of America, 2013/02/19, Volume 110, Issue 8, p.2946-51, (2013) Read More / View Supplemental Materials
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Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study.de Miguel-Yanes, JM, Porneala B., Pencina MJ, Fox CS, Florez JC, Siscovick DS, Dupuis J., and Meigs JB Journal of hypertension, 2013/02/19, (2013) Read More / View Supplemental Materials
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Potent and Selective Inhibition of Histone Deacetylase 6 (HDAC6) Does Not Require a Surface-Binding Motif.Wagner, FF, Olson DE, Gale JP, Kaya T., Weïwer M., Aidoud N., Thomas M., Davoine EL, Lemercier BC, Zhang YL, and Holson EB Journal of medicinal chemistry, 2013/02/18, (2013) Read More / View Supplemental Materials
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Evolution and impact of subclonal mutations in chronic lymphocytic leukemia.Landau, DA, Carter SL, Stojanov P., McKenna A., Stevenson K., Lawrence MS, Sougnez C., Stewart C., Sivachenko A., Wang L., Wan Y., Zhang W., Shukla SA, Vartanov A., Fernandes SM, Saksena G., Cibulskis K., Tesar B., Gabriel S., Hacohen N., et al. Cell, 2013/02/14, Volume 152, Issue 4, p.714-26, (2013) Read More / View Supplemental Materials
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Identifying recent adaptations in large-scale genomic data.Grossman, SR, Andersen KG, Shlyakhter I., Tabrizi S., Winnicki S., Yen A., Park DJ, Griesemer D., Karlsson EK, Wong SH, Cabili M., Adegbola RA, Bamezai RN, Hill AV, Vannberg FO, Rinn JL, 1000 Genomes Project, Lander E. S., Schaffner SF, and Sabeti PC Cell, 2013/02/14, Volume 152, Issue 4, p.703-13, (2013) Read More / View Supplemental Materials
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Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant.Kamberov, YG, Wang S., Tan J., Gerbault P., Wark A., Tan L., Yang Y., Li S., Tang K., Chen H., Powell A., Itan Y., Fuller D., Lohmueller J., Mao J., Schachar A., Paymer M., Hostetter E., Byrne E., Burnett M., et al. Cell, 2013/02/14, Volume 152, Issue 4, p.691-702, (2013) Read More / View Supplemental Materials
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APOL1 variants and kidney disease in people of recent African ancestry.Genovese, G., Friedman DJ, and Pollak MR Nature reviews. Nephrology, 2013/02/12, Volume 9, Issue 4, p.240-4, (2013) Read More / View Supplemental Materials
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DNA methylation: roles in mammalian development.Smith, ZD, and Meissner A. Nature reviews. Genetics, 2013/02/12, Volume 14, Issue 3, p.204-20, (2013) Read More / View Supplemental Materials
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Photochemical activation of TRPA1 channels in neurons and animals.Kokel, D., Cheung CY, Mills R., Coutinho-Budd J., Huang L., Setola V., Sprague J., Jin S., Jin YN, Huang XP, Bruni G., Woolf CJ, Roth BL, Hamblin MR, Zylka MJ, Milan DJ, and Peterson RT Nature chemical biology, 2013/02/10, (2013) Read More / View Supplemental Materials
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Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples.Cibulskis, K., Lawrence MS, Carter SL, Sivachenko A., Jaffe D., Sougnez C., Gabriel S., Meyerson M., Lander E. S., and Getz G. Nature biotechnology, 2013/02/10, (2013) Read More / View Supplemental Materials
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The simplest explanation: passive DNA demethylation in PGCs.Smith, ZD, and Meissner A. The EMBO journal, 2013/02/06, Volume 32, Issue 3, p.318-21, (2013) Read More / View Supplemental Materials
Chromatin marks identify critical cell types for fine mapping complex trait variants.Trynka, G., Sandor C., Han B., Xu H., Stranger BE, Liu XS, and Raychaudhuri S. Nature genetics, 2013/02/01, Volume 45, Issue 2, p.124-30, (2013) Read More / View Supplemental Materials
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Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency.Kiezun, A., Pulit SL, Francioli LC, van Dijk F., Swertz M., Boomsma DI, van Duijn CM, Slagboom PE, van Ommen GJ, Wijmenga C., Genome of the Netherlands Consortium, de Bakker PI, and Sunyaev SR PLoS genetics, 2013/02/01, Volume 9, Issue 2, p.e1003301, (2013) Read More / View Supplemental Materials
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Fine-scale mapping of the nasonia genome to chromosomes using a high-density genotyping microarray.Desjardins, CA, Gadau J., Lopez JA, Niehuis O., Avery AR, Loehlin DW, Richards S., Colbourne JK, and Werren JH G3 (Bethesda, Md.), 2013/02/01, Volume 3, Issue 2, p.205-15, (2013) Read More / View Supplemental Materials
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Histone acetylation: molecular mnemonics on the chromatin.Gräff, J., and Tsai LH Nature reviews. Neuroscience, 2013/02/01, Volume 14, Issue 2, p.97-111, (2013) Read More / View Supplemental Materials
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Large-scale metagenomic sequence clustering on map-reduce clusters.Yang, X., Zola J., and Aluru S. Journal of bioinformatics and computational biology, 2013/02/01, Volume 11, Issue 1, p.1340001, (2013) Read More / View Supplemental Materials
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Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors.Chmielecki, J., Crago AM, Rosenberg M., O'Connor R., Walker SR, Ambrogio L., Auclair D., McKenna A., Heinrich MC, Frank DA, and Meyerson M. Nature genetics, 2013/02/01, Volume 45, Issue 2, p.131-2, (2013) Read More / View Supplemental Materials
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Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues.Zhu, J., Adli M., Zou JY, Verstappen G., Coyne M., Zhang X., Durham T., Miri M., Deshpande V., De Jager PL, Bennett DA, Houmard JA, Muoio DM, Onder TT, Camahort R., Cowan CA, Meissner A., Epstein CB, Shoresh N., and Bernstein BE Cell, 2013/01/31, Volume 152, Issue 3, p.642-54, (2013) Read More / View Supplemental Materials
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Integrative eQTL-Based Analyses Reveal the Biology of Breast Cancer Risk Loci.Li, Q., Seo JH, Stranger B., McKenna A., Pe'er I., LaFramboise T., Brown M., Tyekucheva S., and Freedman ML Cell, 2013/01/31, Volume 152, Issue 3, p.633-41, (2013) Read More / View Supplemental Materials
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Epigenetic mechanisms in mood disorders: Targeting neuroplasticity.Fass, DM, Schroeder FA, Perlis RH, and Haggarty SJ Neuroscience, 2013/01/30, (2013) Read More / View Supplemental Materials
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Eukaryotic virulence determinants utilize phosphoinositides at the ER and host cell surface.Jiang, RH, Stahelin RV, Bhattacharjee S., and Haldar K. Trends in microbiology, 2013/01/29, (2013) Read More / View Supplemental Materials
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Human systems immunology: Hypothesis-based modeling and unbiased data-driven approaches.Arazi, A., Pendergraft WF 3rd, Ribeiro RM, Perelson AS, and Hacohen N. Seminars in immunology, 2013/01/29, (2013) Read More / View Supplemental Materials
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Highly Recurrent TERT Promoter Mutations in Human Melanoma.Huang, FW, Hodis E., Xu MJ, Kryukov GV, Chin L., and Garraway LA Science (New York, N.Y.), 2013/01/24, (2013) Read More / View Supplemental Materials
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Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders.Lim, ET, Raychaudhuri S., Sanders SJ, Stevens C., Sabo A., Macarthur DG, Neale BM, Kirby A., Ruderfer DM, Fromer M., Lek M., Liu L., Flannick J., Ripke S., Nagaswamy U., Muzny D., Reid JG, Hawes A., Newsham I., Wu Y., et al. Neuron, 2013/01/23, Volume 77, Issue 2, p.235-42, (2013) Read More / View Supplemental Materials
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Using Whole-Exome Sequencing to Identify Inherited Causes of Autism.Yu, TW, Chahrour MH, Coulter ME, Jiralerspong S., Okamura-Ikeda K., Ataman B., Schmitz-Abe K., Harmin DA, Adli M., Malik AN, D'Gama AM, Lim ET, Sanders SJ, Mochida GH, Partlow JN, Sunu CM, Felie JM, Rodriguez J., Nasir RH, Ware J., et al. Neuron, 2013/01/23, Volume 77, Issue 2, p.259-273, (2013) Read More / View Supplemental Materials
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Ultranet: efficient solver for the sparse inverse covariance selection problem in gene network modeling.Järvstråt, L., Johansson M., Gullberg U., and Nilsson B. Bioinformatics (Oxford, England), 2013/01/21, (2013) Read More / View Supplemental Materials
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The genetic landscape of high-risk neuroblastoma.Pugh, TJ, Morozova O., Attiyeh EF, Asgharzadeh S., Wei JS, Auclair D., Carter SL, Cibulskis K., Hanna M., Kiezun A., Kim J., Lawrence MS, McKenna A., Pedamallu CS, Ramos AH, Shefler E., Sivachenko A., Sougnez C., Stewart C., Ally A., et al. Nature genetics, 2013/01/20, (2013) Read More / View Supplemental Materials
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Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations.Brastianos, PK, Horowitz PM, Santagata S., Jones RT, McKenna A., Getz G., Ligon KL, Palescandolo E., Van Hummelen P., Ducar MD, Raza A., Macconaill LE, Louis DN, Hahn WC, Dunn IF, and Beroukhim R. Nature genetics, 2013/01/20, (2013) Read More / View Supplemental Materials
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Regulation of a viral proteinase by a peptide and DNA in one-dimensional space: IV. viral proteinase slides along DNA to locate and process its substrates.Blainey, PC, Graziano V., Pérez-Berná AJ, McGrath WJ, Flint SJ, San Martín C., Xie XS, and Mangel WF The Journal of biological chemistry, 2013/01/18, Volume 288, Issue 3, p.2092-102, (2013) Read More / View Supplemental Materials
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ATG5 regulates plasma cell differentiation.Conway, KL, Kuballa P., Khor B., Zhang M., Shi HN, Virgin HW, and Xavier RJ Autophagy, 2013/01/17, Volume 9, Issue 4, (2013) Read More / View Supplemental Materials
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Prognostic Gene-Expression Signature for Patients with Hepatitis C-Related Early-Stage Cirrhosis.Hoshida, Y., Villanueva A., Sangiovanni A., Sole M., Hur C., Andersson KL, Chung RT, Gould J., Kojima K., Gupta S., Taylor B., Crenshaw A., Gabriel S., Minguez B., Iavarone M., Friedman SL, Colombo M., Llovet JM, and Golub T. R. Gastroenterology, 2013/01/17, (2013) Read More / View Supplemental Materials
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Mosaic copy number variation in schizophrenia.Ruderfer, DM, Chambert K., Moran J., Talkowski M., Chen ES, Gigek C., Gusella JF, Blackwood DH, Corvin A., Gurling HM, Hultman CM, Kirov G., Magnusson P., O'Donovan MC, Owen MJ, Pato C., St Clair D., Sullivan PF, Purcell SM, Sklar P., et al. European journal of human genetics : EJHG, 2013/01/16, (2013) Read More / View Supplemental Materials
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