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2015
Identification and characterization of latency-associated peptide-expressing γδ T cells.Rezende, RM, da Cunha AP, Kuhn C., Rubino S., M'Hamdi H., Gabriely G., Vandeventer T., Liu S., Cialic R., Pinheiro-Rosa N., Oliveira RP, Gaublomme JT, Obholzer N., Kozubek J., Pochet N., Faria AM, and Weiner HL Nature communications, 2015/12/08, Volume 6, p.8726, (2015) Read More / View Supplemental Materials
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Abundant contribution of short tandem repeats to gene expression variation in humans.Gymrek, M., Willems T., Guilmatre A., Zeng H., Markus B., Georgiev S., Daly M. J., Price AL, Pritchard JK, Sharp AJ, and Erlich Y. Nature genetics, 2015/12/07, (2015) Read More / View Supplemental Materials
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'Deadman' and 'Passcode' microbial kill switches for bacterial containment.Chan, CT, Lee JW, Cameron DE, Bashor CJ, and Collins JJ Nature chemical biology, 2015/12/07, (2015) Read More / View Supplemental Materials
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A Generic and Cell-Type-Specific Wound Response Precedes Regeneration in Planarians.Wurtzel, O., Cote LE, Poirier A., Satija R., Regev A., and Reddien PW Developmental cell, 2015/12/07, Volume 35, Issue 5, p.632-45, (2015) Read More / View Supplemental Materials
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The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins.Li, N., Yousefi M., Nakauka-Ddamba A., Li F., Vandivier L., Parada K., Woo DH, Wang S., Naqvi AS, Rao S., Tobias J., Cedeno RJ, Minuesa G., Y K., Barlowe TS, Valvezan A., Shankar S., Deering RP, Klein PS, Jensen ST, et al. Cell reports, 2015/12/07, (2015) Read More / View Supplemental Materials
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Self-assembled RNA-triple-helix hydrogel scaffold for microRNA modulation in the tumour microenvironment.Conde, J., Oliva N., Atilano M., Song HS, and Artzi N. Nature materials, 2015/12/07, (2015) Read More / View Supplemental Materials
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Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution.Kasar, S., Kim J., Improgo R., Tiao G., Polak P., Haradhvala N., Lawrence MS, Kiezun A., Fernandes SM, Bahl S., Sougnez C., Gabriel S., Lander E. S., Kim HT, Getz G., and Brown JR Nature communications, 2015/12/07, Volume 6, p.8866, (2015) Read More / View Supplemental Materials
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Two unique TUBB3 mutations cause both CFEOM3 and malformations of cortical development.Whitman, MC, Andrews C., Chan WM, Tischfield MA, Stasheff SF, Brancati F., Ortiz-Gonzalez X., Nuovo S., Garaci F., MacKinnon SE, Hunter DG, Grant PE, and Engle EC American journal of medical genetics. Part A, 2015/12/06, (2015) Read More / View Supplemental Materials
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Genomic Instability in Human Pluripotent Stem Cells Arises from Replicative Stress and Chromosome Condensation Defects.Lamm, N., Ben-David U., Golan-Lev T., Storchová Z., Benvenisty N., and Kerem B. Cell stem cell, 2015/12/05, (2015) Read More / View Supplemental Materials
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Convergent Lines of Evidence Support LRP8 as a Susceptibility Gene for Psychosis.Li, M., Huang L., Grigoroiu-Serbanescu M., Bergen SE, Landén M., Hultman CM, Forstner AJ, Strohmaier J., Hecker J., Schulze TG, Müller-Myhsok B., Reif A., Mitchell PB, Martin NG, Cichon S., Nöthen MM, Alkelai A., Lerer B., Jamain S., Leboyer M., et al. Molecular neurobiology, 2015/12/04, (2015) Read More / View Supplemental Materials
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ENIGMA and the Individual: Predicting Factors that Affect the Brain in 35 Countries Worldwide.Thompson, PM, Andreassen OA, Arias-Vasquez A., Bearden CE, Boedhoe PS, Brouwer RM, Buckner RL, Buitelaar JK, Bulaeva KB, Cannon DM, Cohen RA, Conrod PJ, Dale AM, Deary IJ, Dennis EL, de Reus MA, Desrivieres S., Dima D., Donohoe G., Fisher SE, et al. NeuroImage, 2015/12/04, (2015) Read More / View Supplemental Materials
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Pharmacogenomic agreement between two cancer cell line data sets.Cancer Cell Line Encyclopedia, Consortium, and Genomics of Drug Sensitivity in Cancer Consortium Nature, 2015/12/03, Volume 528, Issue 7580, p.84-7, (2015) Read More / View Supplemental Materials
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A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation.Fields, AP, Rodriguez EH, Jovanovic M., Stern-Ginossar N., Haas BJ, Mertins P., Raychowdhury R., Hacohen N., Carr SA, Ingolia NT, Regev A., and Weissman JS Molecular cell, 2015/12/03, Volume 60, Issue 5, p.816-27, (2015) Read More / View Supplemental Materials
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Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems.Murray, E., Cho JH, Goodwin D., Ku T., Swaney J., Kim SY, Choi H., Park YG, Park JY, Hubbert A., McCue M., Vassallo S., Bakh N., Frosch MP, Wedeen VJ, Seung HS, and Chung K. Cell, 2015/12/03, Volume 163, Issue 6, p.1500-14, (2015) Read More / View Supplemental Materials
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Prophages of the genus Bifidobacterium as modulating agents of the infant gut microbiota.Lugli, GA, Milani C., Turroni F., Tremblay D., Ferrario C., Mancabelli L., Duranti S., Ward DV, Ossiprandi MC, Moineau S., van Sinderen D., and Ventura M. Environmental microbiology, 2015/12/02, (2015) Read More / View Supplemental Materials
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Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.D'Gama, AM, Pochareddy S., Li M., Jamuar SS, Reiff RE, Lam AT, Sestan N., and Walsh CA Neuron, 2015/12/02, Volume 88, Issue 5, p.910-7, (2015) Read More / View Supplemental Materials
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A bivariate Genome Wide Association Study (GWAS) of depressive symptoms and lipid levels has identified pleiotropic gene loci.Amare, AT, Cohorts for Heart and Aging Research in Genomic Epidemiology(CHARGE) depression working Group, Global Lipids Genetics Consortium, Nigatu YT, Hsu YH, Lahti J., Alizadeh BZ, and Snieder H. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2015/12/01, Volume 47, Issue Pt A, p.113-4, (2015) Read More / View Supplemental Materials
Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection.Mesquita, RD, Vionette-Amaral RJ, Lowenberger C., Rivera-Pomar R., Monteiro FA, Minx P., Spieth J., Carvalho AB, Panzera F., Lawson D., Torres AQ, Ribeiro JM, Sorgine MH, Waterhouse RM, Montague MJ, Abad-Franch F., Alves-Bezerra M., Amaral LR, Araujo HM, Araujo RN, et al. Proceedings of the National Academy of Sciences of the United States of America, 2015/12/01, Volume 112, Issue 48, p.14936-14941, (2015) Read More / View Supplemental Materials
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High-Specificity Targeted Functional Profiling in Microbial Communities with ShortBRED.Kaminski, J., Gibson MK, Franzosa EA, Segata N., Dantas G., and Huttenhower C. PLoS computational biology, 2015/12/01, Volume 11, Issue 12, p.e1004557, (2015) Read More / View Supplemental Materials
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Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens.March, S., Ramanan V., Trehan K., Ng S., Galstian A., Gural N., Scull MA, Shlomai A., Mota MM, Fleming HE, Khetani SR, Rice CM, and Bhatia SN Nature protocols, 2015/12/01, Volume 10, Issue 12, p.2027-53, (2015) Read More / View Supplemental Materials
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A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men.Petrovics, G., Li H., Stümpel T., Tan SH, Young D., Katta S., Li Q., Ying K., Klocke B., Ravindranath L., Kohaar I., Chen Y., Ribli D., Grote K., Zou H., Cheng J., Dalgard CL, Zhang S., Csabai I., Kagan J., et al. EBioMedicine, 2015/12/01, Volume 2, Issue 12, p.1957-64, (2015) Read More / View Supplemental Materials
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Rationally engineered Cas9 nucleases with improved specificity.Slaymaker, IM, Gao L., Zetsche B., Scott DA, Yan WX, and Zhang F. Science (New York, N.Y.), 2015/12/01, (2015) Read More / View Supplemental Materials
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A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed.Palchaudhuri, R., Lambrecht MJ, Botham RC, Partlow KC, van Ham TJ, Putt KS, Nguyen LT, Kim SH, Peterson RT, Fan TM, and Hergenrother PJ Cell reports, 2015/12/01, Volume 13, Issue 9, p.2027-36, (2015) Read More / View Supplemental Materials
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MERAV: a tool for comparing gene expression across human tissues and cell types.Shaul, YD, Yuan B., Thiru P., Nutter-Upham A., McCallum S., Lanzkron C., Bell GW, and Sabatini DM Nucleic acids research, 2015/11/30, (2015) Read More / View Supplemental Materials
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Addendum: A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages.Lu, H., Clauser KR, Tam WL, Fröse J., Ye X., Eaton EN, Reinhardt F., Donnenberg VS, Bhargava R., Carr SA, and Weinberg R. A. Nature cell biology, 2015/11/27, Volume 17, Issue 12, p.1607, (2015) Read More / View Supplemental Materials
Resources for the design of CRISPR gene editing experiments.Graham, DB, and Root DE Genome biology, 2015/11/27, Volume 16, Issue 1, p.260, (2015) Read More / View Supplemental Materials
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Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy.Dejanovic, B., Djémié T., Grünewald N., Suls A., Kress V., Hetsch F., Craiu D., Zemel M., Gormley P., Lal D., group EuroEPINOMICS Dravet working, Myers CT, Mefford HC, Palotie A., Helbig I., Meier JC, De Jonghe P., Weckhuysen S., and Schwarz G. EMBO molecular medicine, 2015/11/27, (2015) Read More / View Supplemental Materials
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The DNA Ligase IV Syndrome R278H Mutation Impairs B Lymphopoiesis via Error-Prone Nonhomologous End-Joining.Park, J., Welner RS, Chan MY, Troppito L., Staber PB, Tenen D. G., and Yan CT Journal of immunology (Baltimore, Md. : 1950), 2015/11/25, (2015) Read More / View Supplemental Materials
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The structure and timescales of heat perception in larval zebrafish.Haesemeyer, M., Robson DN, Li JM, Schier AF, and Engert F. Cell systems, 2015/11/25, Volume 1, Issue 5, p.338-348, (2015) Read More / View Supplemental Materials
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EDARV370A associated facial characteristics in Uyghur population revealing further pleiotropic effects.Peng, Q., Li J., Tan J., Yang Y., Zhang M., Wu S., Liu Y., Zhang J., Qin P., Guan Y., Jiao Y., Zhang Z., Sabeti PC, Tang K., Xu S., Jin L., and Wang S. Human genetics, 2015/11/24, (2015) Read More / View Supplemental Materials
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Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.Felix, JF, Bradfield JP, Monnereau C., van der Valk RJ, Stergiakouli E., Chesi A., Gaillard R., Feenstra B., Thiering E., Kreiner-Møller E., Mahajan A., Pitkänen N., Joro R., Cavadino A., Huikari V., Franks S., Groen-Blokhuis MM, Cousminer DL, Marsh JA, Lehtimäki T., et al. Human molecular genetics, 2015/11/24, (2015) Read More / View Supplemental Materials
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Smart nanosystems: Bio-inspired technologies that interact with the host environment.Kwon, EJ, Lo JH, and Bhatia SN Proceedings of the National Academy of Sciences of the United States of America, 2015/11/24, Volume 112, Issue 47, p.14460-6, (2015) Read More / View Supplemental Materials
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Synthetic biology devices for in vitro and in vivo diagnostics.Slomovic, S., Pardee K., and Collins JJ Proceedings of the National Academy of Sciences of the United States of America, 2015/11/24, Volume 112, Issue 47, p.14429-35, (2015) Read More / View Supplemental Materials
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Whole-exome sequencing of over 4,100 men of African ancestry and prostate cancer risk.Rand, KA, Rohland N., Tandon A., Stram A., Sheng X., Do R., Pasaniuc B., Allen A., Quinque D., Mallick S., Le Marchand L., Kaggwa S., Lubwama A., African Ancestry Prostate Cancer GWAS Consortium, consortium Ellipse/GAME-ON, Stram DO, Watya S., Henderson BE, Conti DV, Reich D., et al. Human molecular genetics, 2015/11/24, (2015) Read More / View Supplemental Materials
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Advances in discovering small molecules to probe protein function in a systems context.Doyle, SK, Pop MS, Evans HL, and Koehler AN Current opinion in chemical biology, 2015/11/23, Volume 30, p.28-36, (2015) Read More / View Supplemental Materials
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Genome-wide patterns of selection in 230 ancient Eurasians.Mathieson, I., Lazaridis I., Rohland N., Mallick S., Patterson N., Roodenberg SA, Harney E., Stewardson K., Fernandes D., Novak M., Sirak K., Gamba C., Jones ER, Llamas B., Dryomov S., Pickrell J., Arsuaga JL, de Castro JM, Carbonell E., Gerritsen F., et al. Nature, 2015/11/23, (2015) Read More / View Supplemental Materials
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HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis.Ombrello, MJ, Remmers EF, Tachmazidou I., Grom A., Foell D., Haas JP, Martini A., Gattorno M., Özen S., Prahalad S., Zeft AS, Bohnsack JF, Mellins ED, Ilowite NT, Russo R., Len C., Hilario MO, Oliveira S., Yeung RS, Rosenberg A., et al. Proceedings of the National Academy of Sciences of the United States of America, 2015/11/23, (2015) Read More / View Supplemental Materials
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Prediction of Sudden Cardiac Death with Automated High-Throughput Analysis of Heterogeneity in Standard Resting 12-Lead Electrocardiogram.Kenttä, TV, Nearing BD, Porthan K., Tikkanen JT, Viitasalo M., Nieminen MS, Salomaa V., Oikarinen L., Jula A., Kontula K., Newton-Cheh C., Huikuri HV, and Verrier RL Heart rhythm : the official journal of the Heart Rhythm Society, 2015/11/23, (2015) Read More / View Supplemental Materials
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The resurgence of phenotypic screening in drug discovery and development.Wagner, BK Expert opinion on drug discovery, 2015/11/23, (2015) Read More / View Supplemental Materials
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Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathy.Chen, H., Ren S., Clish C., Jain M., Mootha V., McCaffery JM, and Chan DC The Journal of cell biology, 2015/11/23, Volume 211, Issue 4, p.795-805, (2015) Read More / View Supplemental Materials
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GEMS Project: A Platform to Investigate Multiple Sclerosis Risk.Xia, Z., White CC, Owen EK, Von Korff A., Clarkson SR, McCabe CA, Cimpean M., Winn PA, Hoesing A., Steele SU, Cortese IC, Chitnis T., Weiner HL, Reich DS, Chibnik LB, and De Jager PL Annals of neurology, 2015/11/19, (2015) Read More / View Supplemental Materials
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Jagged 1 Rescues the Duchenne Muscular Dystrophy Phenotype.Vieira, NM, Elvers I., Alexander MS, Moreira YB, Eran A., Gomes JP, Marshall JL, Karlsson EK, Verjovski-Almeida S., Lindblad-Toh K., Kunkel LM, and Zatz M. Cell, 2015/11/19, Volume 163, Issue 5, p.1204-13, (2015) Read More / View Supplemental Materials
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Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway.Saxton, RA, Knockenhauer KE, Wolfson RL, Chantranupong L., Pacold ME, Wang T., Schwartz TU, and Sabatini DM Science (New York, N.Y.), 2015/11/19, (2015) Read More / View Supplemental Materials
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CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity.Wang, C., Yosef N., Gaublomme J., Wu C., Lee Y., Clish CB, Kaminski J., Xiao S., Zu Horste GM, Pawlak M., Kishi Y., Joller N., Karwacz K., Zhu C., Ordovas-Montanes M., Madi A., Wortman I., Miyazaki T., Sobel RA, Park H., et al. Cell, 2015/11/18, (2015) Read More / View Supplemental Materials
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Silent pericentromeric repeats speak out.Younger, ST, and Rinn JL Proceedings of the National Academy of Sciences of the United States of America, 2015/11/18, (2015) Read More / View Supplemental Materials
Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity.Gaublomme, JT, Yosef N., Lee Y., Gertner RS, Yang LV, Wu C., Pandolfi PP, Mak T., Satija R., Shalek AK, Kuchroo VK, Park H., and Regev A. Cell, 2015/11/18, (2015) Read More / View Supplemental Materials
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COMT Val 158 Met polymorphism is associated with nonverbal cognition following mild traumatic brain injury.Winkler, EA, Yue JK, McAllister TW, Temkin NR, Oh SS, Burchard EG, Hu D., Ferguson AR, Lingsma HF, Burke JF, Sorani MD, Rosand J., Yuh EL, Barber J., Tarapore PE, Gardner RC, Sharma S., Satris GG, Eng C., Puccio AM, et al. Neurogenetics, 2015/11/17, (2015) Read More / View Supplemental Materials
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Society for Pediatric Research 2015 Young Investigator Award: Genetics of human hematopoiesis-What patients can teach us about blood cell production.Wakabayashi, A., and Sankaran VG Pediatric research, 2015/11/17, (2015) Read More / View Supplemental Materials
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Stochastic electrotransport selectively enhances the transport of highly electromobile molecules.Kim, SY, Cho JH, Murray E., Bakh N., Choi H., Ohn K., Ruelas L., Hubbert A., McCue M., Vassallo SL, Keller PJ, and Chung K. Proceedings of the National Academy of Sciences of the United States of America, 2015/11/17, Volume 112, Issue 46, p.E6274-83, (2015) Read More / View Supplemental Materials
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The contribution of rare variation to prostate cancer heritability.Mancuso, N., Rohland N., Rand KA, Tandon A., Allen A., Quinque D., Mallick S., Li H., Stram A., Sheng X., Kote-Jarai Z., Easton DF, Eeles RA, consortium Practical, Le Marchand L., Lubwama A., Stram D., Watya S., Conti DV, Henderson B., et al. Nature genetics, 2015/11/16, (2015) Read More / View Supplemental Materials
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Does developmental timing of exposure to child maltreatment predict memory performance in adulthood? Results from a large, population-based sample.Dunn, EC, Busso DS, Raffeld MR, Smoller JW, Nelson CA, Doyle AE, and Luk G. Child abuse & neglect, 2015/11/13, (2015) Read More / View Supplemental Materials
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Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity.Dudani, JS, Jain PK, Kwong GA, Stevens KR, and Bhatia SN ACS nano, 2015/11/13, (2015) Read More / View Supplemental Materials
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Summaries of plenary, symposia, and oral sessions at the XXII World Congress of Psychiatric Genetics, Copenhagen, Denmark, 12-16 October 2014.Aas, M., Blokland GA, Chawner SJ, Choi SW, Estrada J., Forsingdal A., Friedrich M., Ganesham S., Hall L., Haslinger D., Huckins L., Loken E., Malan-Müller S., Martin J., Misiewicz Z., Pagliaroli L., Pardiñas AF, Pisanu C., Quadri G., Santoro ML, et al. Psychiatric genetics, 2015/11/12, (2015) Read More / View Supplemental Materials
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Definitive Localization of Intracellular Proteins: Novel Approach Using CRISPR-Cas9 Genome Editing, with Glucose 6-Phosphate Dehydrogenase as a Model.Spencer, NY, Yan Z., Cong L., Zhang Y., Engelhardt JF, and Stanton RC Analytical biochemistry, 2015/11/11, (2015) Read More / View Supplemental Materials
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Expansion of Interstitial Telomeric Sequences in Yeast.Aksenova, AY, Han G., Shishkin AA, Volkov KV, and Mirkin SM Cell reports, 2015/11/11, (2015) Read More / View Supplemental Materials
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Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates.Palamara, PF, Francioli LC, Wilton PR, Genovese G., Gusev A., Finucane HK, Sankararaman S., Genome of the Netherlands Consortium, Sunyaev SR, de Bakker PI, Wakeley J., Pe'er I., and Price AL American journal of human genetics, 2015/11/11, (2015) Read More / View Supplemental Materials
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Flow Cytometric Analysis of Mononuclear Phagocytes in Non-diseased Human Lung and Lung-draining Lymph Nodes.Desch, AN, Gibbings SL, Goyal R., Kolde R., Bednarek J., Bruno T., Slansky JE, Jacobelli J., Mason R., Ito Y., Messier E., Randolph GJ, Prabagar M., Atif SM, Segura E., Xavier RJ, Bratton DL, Janssen WJ, Henson PM, and Jakubzick CV American journal of respiratory and critical care medicine, 2015/11/09, (2015) Read More / View Supplemental Materials
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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.Gaulton, KJ, Ferreira T., Lee Y., Raimondo A., Mägi R., Reschen ME, Mahajan A., Locke A., William Rayner N., Robertson N., Scott RA, Prokopenko I., Scott LJ, Green T., Sparso T., Thuillier D., Yengo L., Grallert H., Wahl S., Frånberg M., et al. Nature genetics, 2015/11/09, (2015) Read More / View Supplemental Materials
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Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load.McLaren, PJ, Coulonges C., Bartha I., Lenz TL, Deutsch AJ, Bashirova A., Buchbinder S., Carrington MN, Cossarizza A., Dalmau J., De Luca A., Goedert JJ, Gurdasani D., Haas DW, Herbeck JT, Johnson EO, Kirk GD, Lambotte O., Luo M., Mallal S., et al. Proceedings of the National Academy of Sciences of the United States of America, 2015/11/09, (2015) Read More / View Supplemental Materials
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Shared genetic aetiology of puberty timing between sexes and with health-related outcomes.Day, FR, Bulik-Sullivan B., Hinds DA, Finucane HK, Murabito JM, Tung JY, Ong KK, and Perry JR Nature communications, 2015/11/09, Volume 6, p.8842, (2015) Read More / View Supplemental Materials
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SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2.Kim, KH, Kim W., Howard TP, Vazquez F., Tsherniak A., Wu JN, Wang W., Haswell JR, Walensky LD, Hahn WC, Orkin SH, and Roberts CW Nature medicine, 2015/11/09, (2015) Read More / View Supplemental Materials
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Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems.Shmakov, S., Abudayyeh OO, Makarova KS, Wolf YI, Gootenberg JS, Semenova E., Minakhin L., Joung J., Konermann S., Severinov K., Zhang F., and Koonin EV Molecular cell, 2015/11/05, Volume 60, Issue 3, p.385-97, (2015) Read More / View Supplemental Materials
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Draft Genome Sequence of Cercospora arachidicola, Causal Agent of Early Leaf Spot in Peanuts.Orner, VA, Cantonwine EG, Wang XM, Abouelleil A., Bochicchio J., Nusbaum C., Culbreath AK, Abdo Z., and Arias RS Genome announcements, 2015/11/05, Volume 3, Issue 6, (2015) Read More / View Supplemental Materials
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Functional implications of disease-specific variants in loci jointly associated to coeliac disease and rheumatoid arthritis.Gutierrez-Achury, J., Zorro MM, Ricaño-Ponce I., Zhernakova DV, consortium Coeliac Disease Immunochip consortium, RACI, Diogo D., Raychaudhuri S., Franke L., Trynka G., Wijmenga C., and Zhernakova A. Human molecular genetics, 2015/11/05, (2015) Read More / View Supplemental Materials
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LARS2 Variants Associated with Hydrops, Lactic Acidosis, Sideroblastic Anemia, and Multisystem Failure.Riley, LG, Rudinger-Thirion J., Schmitz-Abe K., Thorburn DR, Davis RL, Teo J., Arbuckle S., Cooper ST, Campagna DR, Frugier M., Markianos K., Sue CM, Fleming MD, and Christodoulou J. JIMD reports, 2015/11/05, (2015) Read More / View Supplemental Materials
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Two-Variance-Component Model Improves Genetic Prediction in Family Datasets.Tucker, G., Loh PR, MacLeod IM, Hayes BJ, Goddard ME, Berger B., and Price AL American journal of human genetics, 2015/11/05, Volume 97, Issue 5, p.677-90, (2015) Read More / View Supplemental Materials
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CellProfiler Tracer: exploring and validating high-throughput, time-lapse microscopy image data.Bray, MA, and Carpenter AE BMC bioinformatics, 2015/11/04, Volume 16, p.368, (2015) Read More / View Supplemental Materials
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Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomisation Meta-Analysis in the CARTA Consortium.Linneberg, A., Jacobsen RK, Skaaby T., Taylor AE, Fluharty ME, Jeppesen JL, Bjørngaard JH, Åsvold BO, Gabrielsen ME, Campbell A., Marioni RE, Kumari M., Marques-Vidal P., Kaakinen M., Cavadino A., Postmus I., Ahluwalia TS, Wannamethee SG, Lahti J., Räikkönen K., et al. Circulation. Cardiovascular genetics, 2015/11/04, (2015) Read More / View Supplemental Materials
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Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease.Karaca, E., Harel T., Pehlivan D., Jhangiani SN, Gambin T., Coban Akdemir Z., Gonzaga-Jauregui C., Erdin S., Bayram Y., Campbell IM, Hunter JV, Atik MM, Van Esch H., Yuan B., Wiszniewski W., Isikay S., Yesil G., Yuregir OO, Tug Bozdogan S., Aslan H., et al. Neuron, 2015/11/04, Volume 88, Issue 3, p.499-513, (2015) Read More / View Supplemental Materials
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History and genomic sequence analysis of the herpes simplex virus 1 KOS and KOS1.1 sub-strains.Colgrove, RC, Liu X., Griffiths A., Raja P., Deluca NA, Newman RM, Coen DM, and Knipe DM Virology, 2015/11/04, Volume 487, p.215-221, (2015) Read More / View Supplemental Materials
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Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage.Belenky, P., Ye JD, Porter CB, Cohen NR, Lobritz MA, Ferrante T., Jain S., Korry BJ, Schwarz EG, Walker GC, and Collins JJ Cell reports, 2015/11/03, Volume 13, Issue 5, p.968-80, (2015) Read More / View Supplemental Materials
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Complete Genome Sequences and Analysis of the Fusobacterium nucleatum subspecies animalis 7-1 Bacteriophage ɸFunu1 and ɸFunu2.Cochrane, K., McGuire AM, Priest ME, Abouelleil A., Cerqueira GC, Lo R., Earl AM, and Allen-Vercoe E. Anaerobe, 2015/11/03, (2015) Read More / View Supplemental Materials
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A Metabolic Signature of Mitochondrial Dysfunction Revealed through a Monogenic Form of Leigh Syndrome.Thompson Legault, J., Strittmatter L., Tardif J., Sharma R., Tremblay-Vaillancourt V., Aubut C., Boucher G., Clish CB, Cyr D., Daneault C., Waters PJ, LSFC Consortium, Vachon L., Morin C., Laprise C., Rioux JD, Mootha VK, and Des Rosiers C. Cell reports, 2015/11/03, Volume 13, Issue 5, p.981-9, (2015) Read More / View Supplemental Materials
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Characterization of Intestinal Microbiota in Ulcerative Colitis Patients with and without Primary Sclerosing Cholangitis.Kevans, D., Tyler AD, Holm K., Jørgensen KK, Vatn MH, Karlsen TH, Kaplan GG, Eksteen B., Gevers D., Hov JR, and Silverberg MS Journal of Crohn's & colitis, 2015/11/02, (2015) Read More / View Supplemental Materials
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Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis.Loh, PR, Bhatia G., Gusev A., Finucane HK, Bulik-Sullivan BK, Pollack SJ, Schizophrenia Working Group of the Psychiatric Genomics Consortium, de Candia TR, Lee SH, Wray NR, Kendler KS, O'Donovan MC, Neale BM, Patterson N., and Price AL Nature genetics, 2015/11/02, (2015) Read More / View Supplemental Materials
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Lifestyle and metformin ameliorate insulin sensitivity independently of the genetic burden of established insulin resistance variants in Diabetes Prevention Program participants.Hivert, MF, Christophi CA, Franks PW, Jablonski KA, Ehrmann DA, Kahn SE, Horton ES, Pollin TI, Mather KJ, Perreault L., Barrett-Connor E., Knowler WC, Florez JC, and Diabetes Prevention Program Research Group Diabetes, 2015/11/02, (2015) Read More / View Supplemental Materials
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50 Years of Emmonsia Disease in Humans: The Dramatic Emergence of a Cluster of Novel Fungal Pathogens.Schwartz, IS, Kenyon C., Feng P., Govender NP, Dukik K., Sigler L., Jiang Y., Stielow JB, Muñoz JF, Cuomo CA, Botha A., Stchigel AM, and de Hoog GS PLoS pathogens, 2015/11/01, Volume 11, Issue 11, p.e1005198, (2015) Read More / View Supplemental Materials
The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis.Pomerantz, MM, Li F., Takeda DY, Lenci R., Chonkar A., Chabot M., Cejas P., Vazquez F., Cook J., Shivdasani RA, Bowden M., Lis R., Hahn WC, Kantoff PW, Brown M., Loda M., Long HW, and Freedman ML Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1346-51, (2015) Read More / View Supplemental Materials
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Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes.Lipson, M., Loh PR, Sankararaman S., Patterson N., Berger B., and Reich D. PLoS genetics, 2015/11/01, Volume 11, Issue 11, p.e1005550, (2015) Read More / View Supplemental Materials
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Gender Disparity and Mutation Burden in Metastatic Melanoma.Gupta, S., Artomov M., Goggins W., Daly M., and Tsao H. Journal of the National Cancer Institute, 2015/11/01, Volume 107, Issue 11, (2015) Read More / View Supplemental Materials
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Genome-Wide Association Study of Golden Retrievers Identifies Germ-Line Risk Factors Predisposing to Mast Cell Tumours.Arendt, ML, Melin M., Tonomura N., Koltookian M., Courtay-Cahen C., Flindall N., Bass J., Boerkamp K., Megquir K., Youell L., Murphy S., McCarthy C., London C., Rutteman GR, Starkey M., and Lindblad-Toh K. PLoS genetics, 2015/11/01, Volume 11, Issue 11, p.e1005647, (2015) Read More / View Supplemental Materials
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The genomic landscape of juvenile myelomonocytic leukemia.Stieglitz, E., Taylor-Weiner AN, Chang TY, Gelston LC, Wang YD, Mazor T., Esquivel E., Yu A., Seepo S., Olsen SR, Rosenberg M., Archambeault SL, Abusin G., Beckman K., Brown PA, Briones M., Carcamo B., Cooper T., Dahl GV, Emanuel PD, et al. Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1326-33, (2015) Read More / View Supplemental Materials
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Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.Day, FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N., Chasman DI, Stolk L., Finucane HK, Sulem P., Bulik-Sullivan B., Esko T., Johnson AD, Elks CE, Franceschini N., He C., Altmaier E., Brody JA, Franke LL, Huffman JE, Keller MF, et al. Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1294-303, (2015) Read More / View Supplemental Materials
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Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape.Shell, SS, Wang J., Lapierre P., Mir M., Chase MR, Pyle MM, Gawande R., Ahmad R., Sarracino DA, Ioerger TR, Fortune SM, Derbyshire KM, Wade JT, and Gray TA PLoS genetics, 2015/11/01, Volume 11, Issue 11, p.e1005641, (2015) Read More / View Supplemental Materials
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Whole-brain activity mapping onto a zebrafish brain atlas.Randlett, O., Wee CL, Naumann EA, Nnaemeka O., Schoppik D., Fitzgerald JE, Portugues R., Lacoste AM, Riegler C., Engert F., and Schier AF Nature methods, 2015/11/01, Volume 12, Issue 11, p.1039-1046, (2015) Read More / View Supplemental Materials
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Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women.Griesbeck, M., Ziegler S., Laffont S., Smith N., Chauveau L., Tomezsko P., Sharei A., Kourjian G., Porichis F., Hart M., Palmer CD, Sirignano M., Beisel C., Hildebrandt H., Cénac C., Villani AC, Diefenbach TJ, Le Gall S., Schwartz O., Herbeuval JP, et al. Journal of immunology (Baltimore, Md. : 1950), 2015/10/30, (2015) Read More / View Supplemental Materials
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Bifidobacteria exhibit social behavior through carbohydrate resource sharing in the gut.Milani, C., Andrea Lugli G., Duranti S., Turroni F., Mancabelli L., Ferrario C., Mangifesta M., Hevia A., Viappiani A., Scholz M., Arioli S., Sanchez B., Lane J., Ward DV, Hickey R., Mora D., Segata N., Margolles A., van Sinderen D., and Ventura M. Scientific reports, 2015/10/28, Volume 5, p.15782, (2015) Read More / View Supplemental Materials
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Fluid Spatial Dynamics of West Nile Virus in the USA: Rapid Spread in a Permissive Host Environment.Di Giallonardo, F., Geoghegan JL, Docherty DE, McLean RG, Zody MC, Qu J., Yang X., Birren BW, Malboeuf CM, Newman RM, Ip HS, and Holmes EC Journal of virology, 2015/10/28, (2015) Read More / View Supplemental Materials
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Small island, big genetic discoveries.Lettre, G., and Hirschhorn JN Nature genetics, 2015/10/28, Volume 47, Issue 11, p.1224-5, (2015) Read More / View Supplemental Materials
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Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.Song, J., Bergen SE, Di Florio A., Karlsson R., Charney A., Ruderfer DM, Stahl EA, Members of the International Cohort Collection for Bipolar Disorder(ICCBD), Chambert KD, Moran JL, Gordon-Smith K., Forty L., Green EK, Jones I., Jones L., Scolnick EM, Sklar P., Smoller JW, Lichtenstein P., Hultman C., et al. Molecular psychiatry, 2015/10/27, (2015) Read More / View Supplemental Materials
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A perspective on stem cell modeling of Amyotrophic Lateral Sclerosis.de Boer, AS, and Eggan K. Cell cycle (Georgetown, Tex.), 2015/10/27, (2015) Read More / View Supplemental Materials
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A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs.Choi, J., Lee S., Mallard W., Clement K., Tagliazucchi GM, Lim H., Choi IY, Ferrari F., Tsankov AM, Pop R., Lee G., Rinn JL, Meissner A., Park PJ, and Hochedlinger K. Nature biotechnology, 2015/10/26, (2015) Read More / View Supplemental Materials
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Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis.Wagschal, A., Najafi-Shoushtari SH, Wang L., Goedeke L., Sinha S., deLemos AS, Black JC, Ramírez CM, Li Y., Tewhey R., Hatoum I., Shah N., Lu Y., Kristo F., Psychogios N., Vrbanac V., Lu YC, Hla T., de Cabo R., Tsang JS, et al. Nature medicine, 2015/10/26, (2015) Read More / View Supplemental Materials
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Lenalidomide: deciphering mechanisms of action in myeloma, myelodysplastic syndrome and beyond.Guirguis, AA, and Ebert BL Current opinion in cell biology, 2015/10/26, Volume 37, p.61-67, (2015) Read More / View Supplemental Materials
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A qPCR ScoreCard quantifies the differentiation potential of human pluripotent stem cells.Tsankov, AM, Akopian V., Pop R., Chetty S., Gifford CA, Daheron L., Tsankova NM, and Meissner A. Nature biotechnology, 2015/10/26, (2015) Read More / View Supplemental Materials
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BGT: efficient and flexible genotype query across many samples.Li, H. Bioinformatics (Oxford, England), 2015/10/24, (2015) Read More / View Supplemental Materials
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Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes.Sanborn, AL, Rao SS, Huang SC, Durand NC, Huntley MH, Jewett AI, Bochkov ID, Chinnappan D., Cutkosky A., Li J., Geeting KP, Gnirke A., Melnikov A., McKenna D., Stamenova EK, Lander E. S., and Aiden EL Proceedings of the National Academy of Sciences of the United States of America, 2015/10/23, (2015) Read More / View Supplemental Materials
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Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.Raj, L., Ide T., Gurkar AU, Foley M., Schenone M., Li X., Tolliday NJ, Golub T. R., Carr SA, Shamji AF, Stern AM, Mandinova A., Schreiber SL, and Lee SW Nature, 2015/10/22, Volume 526, Issue 7574, p.596, (2015) Read More / View Supplemental Materials
Genome-wide genetic homogeneity between sexes and populations for human height and body mass index.Yang, J., Bakshi A., Zhu Z., Hemani G., Vinkhuyzen AA, Nolte IM, van Vliet-Ostaptchouk JV, Snieder H., study LifeLines Cohort, Esko T., Milani L., Mägi R., Metspalu A., Hamsten A., Magnusson PK, Pedersen NL, Ingelsson E., and Visscher PM Human molecular genetics, 2015/10/22, (2015) Read More / View Supplemental Materials
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Mutations driving CLL and their evolution in progression and relapse.Landau, DA, Tausch E., Taylor-Weiner AN, Stewart C., Reiter JG, Bahlo J., Kluth S., Bozic I., Lawrence M., Böttcher S., Carter SL, Cibulskis K., Mertens D., Sougnez CL, Rosenberg M., Hess JM, Edelmann J., Kless S., Kneba M., Ritgen M., et al. Nature, 2015/10/22, Volume 526, Issue 7574, p.525-30, (2015) Read More / View Supplemental Materials
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