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2016
Label-free cell cycle analysis for high-throughput imaging flow cytometry.Blasi, T., Hennig H., Summers HD, Theis FJ, Cerveira J., Patterson JO, Davies D., Filby A., Carpenter AE, and Rees P. Nature communications, 2016/01/07, Volume 7, p.10256, (2016) Read More / View Supplemental Materials
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Training the Future Leaders in Personalized Medicine.Mason-Suares, H., Sweetser DA, Lindeman NI, and Morton CC Journal of personalized medicine, 2016/01/07, Volume 6, Issue 1, (2016) Read More / View Supplemental Materials
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The (in)famous GWAS P-value threshold revisited and updated for low-frequency variants.Fadista, J., Manning AK, Florez JC, and Groop L. European journal of human genetics : EJHG, 2016/01/06, (2016) Read More / View Supplemental Materials
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A Genome-wide RNAi Screen for Microtubule Bundle Formation and Lysosome Motility Regulation in Drosophila S2 Cells.Jolly, AL, Luan CH, Dusel BE, Dunne SF, Winding M., Dixit VJ, Robins C., Saluk JL, Logan DJ, Carpenter AE, Sharma M., Dean D., Cohen AR, and Gelfand VI Cell reports, 2016/01/06, (2016) Read More / View Supplemental Materials
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Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects.Zhou, Y., Kaiser T., Monteiro P., Zhang X., Van der Goes MS, Wang D., Barak B., Zeng M., Li C., Lu C., Wells M., Amaya A., Nguyen S., Lewis M., Sanjana N., Zhou Y., Zhang M., Zhang F., Fu Z., and Feng G. Neuron, 2016/01/06, Volume 89, Issue 1, p.147-62, (2016) Read More / View Supplemental Materials
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A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages.Kimmerling, RJ, Lee Szeto G., Li JW, Genshaft AS, Kazer SW, Payer KR, de Riba Borrajo J., Blainey PC, Irvine DJ, Shalek AK, and Manalis SR Nature communications, 2016/01/06, Volume 7, p.10220, (2016) Read More / View Supplemental Materials
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Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.Hu, SS, Lin CY, He HH, Witwicki RM, Tabassum DP, Roberts JM, Janiszewska M., Jin Huh S., Liang Y., Ryan J., Doherty E., Mohammed H., Guo H., Stover DG, Ekram MB, Peluffo G., Brown J., D'Santos C., Krop IE, Dillon D., et al. Nature, 2016/01/06, (2016) Read More / View Supplemental Materials
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Role of Tet1/3 Genes and Chromatin Remodeling Genes in Cerebellar Circuit Formation.Zhu, X., Girardo D., Govek EE, John K., Mellén M., Tamayo P., Mesirov J. P., and Hatten ME Neuron, 2016/01/06, Volume 89, Issue 1, p.100-12, (2016) Read More / View Supplemental Materials
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Common Variation in Atrial Fibrillation: Navigating the Path from Genetic Association to Mechanism.Tucker, NR, Clauss S., and Ellinor PT Cardiovascular research, 2016/01/04, (2016) Read More / View Supplemental Materials
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Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry.Figueroa, JD, Middlebrooks CD, Banday AR, Ye Y., Garcia-Closas M., Chatterjee N., Koutros S., Kiemeney LA, Rafnar T., Bishop T., Barnes HF, Matullo G., Golka K., Gago-Dominguez M., Taylor J., Fletcher T., Siddiq A., Cortessis VK, Kooperberg C., Cussenot O., et al. Human molecular genetics, 2016/01/04, (2016) Read More / View Supplemental Materials
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Lipid droplets go nuclear.Farese RV, Jr, and Walther TC The Journal of cell biology, 2016/01/04, Volume 212, Issue 1, p.7-8, (2016) Read More / View Supplemental Materials
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A twin study of rheumatoid arthritis in the Japanese population.Terao, C., Ikari K., Nakayamada S., Takahashi Y., Yamada R., Ohmura K., Hashimoto M., Furu M., Ito H., Fujii T., Yoshida S., Saito K., Taniguchi A., Momohara S., Yamanaka H., Mimori T., and Matsuda F. Modern rheumatology / the Japan Rheumatism Association, 2016/01/04, p.1-22, (2016) Read More / View Supplemental Materials
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).Klionsky, DJ, Abdelmohsen K., Abe A., Abedin MJ, Abeliovich H., Acevedo Arozena A., Adachi H., Adams CM, Adams PD, Adeli K., Adhihetty PJ, Adler SG, Agam G., Agarwal R., Aghi MK, Agnello M., Agostinis P., Aguilar PV, Aguirre-Ghiso J., Airoldi EM, et al. Autophagy, 2016/01/02, Volume 12, Issue 1, p.1-222, (2016) Read More / View Supplemental Materials
Adaptive Landscape by Environment Interactions Dictate Evolutionary Dynamics in Models of Drug Resistance.Ogbunugafor, CB, Wylie CS, Diakite I., Weinreich DM, and Hartl DL PLoS computational biology, 2016/01/01, Volume 12, Issue 1, p.e1004710, (2016) Read More / View Supplemental Materials
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Ancient Haplotypes at the 15q24.2 Microdeletion Region Are Linked to Brain Expression of MAN2C1 and Children's Intelligence.Cáceres, A., Esko T., Pappa I., Gutiérrez A., Lopez-Espinosa MJ, Llop S., Bustamante M., Tiemeier H., Metspalu A., Joshi PK, Wilsonx JF, Reina-Castillón J., Shin J., Pausova Z., Paus T., Sunyer J., Pérez-Jurado LA, and González JR PloS one, 2016/01/01, Volume 11, Issue 6, p.e0157739, (2016) Read More / View Supplemental Materials
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Applications of CRISPR-Cas systems in neuroscience.Heidenreich, M., and Zhang F. Nature reviews. Neuroscience, 2016/01/01, Volume 17, Issue 1, p.36-44, (2016) Read More / View Supplemental Materials
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Associations between plasma branched-chain amino acids, β-aminoisobutyric acid and body composition.Rietman, A., Stanley TL, Clish C., Mootha V., Mensink M., Grinspoon SK, and Makimura H. Journal of nutritional science, 2016/01/01, Volume 5, p.e6, (2016) Read More / View Supplemental Materials
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Baiting for Cancer: Using the Zebrafish as a Model in Liver and Pancreatic Cancer.Hwang, KL, and Goessling W. Advances in experimental medicine and biology, 2016/01/01, Volume 916, p.391-410, (2016) Read More / View Supplemental Materials
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CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis.Sosulski, A., Horn H., Zhang L., Coletti C., Vathipadiekal V., Castro CM, Birrer MJ, Nagano O., Saya H., Lage K., Donahoe PK, and Pépin D. PloS one, 2016/01/01, Volume 11, Issue 6, p.e0156595, (2016) Read More / View Supplemental Materials
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Comparative Transcriptomics in Yeasts.Thompson, DA Methods in molecular biology (Clifton, N.J.), 2016/01/01, Volume 1361, p.67-76, (2016) Read More / View Supplemental Materials
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Consent Codes: Upholding Standard Data Use Conditions.Dyke, SO, Philippakis AA, Rambla De Argila J., Paltoo DN, Luetkemeier ES, Knoppers BM, Brookes AJ, Spalding JD, Thompson M., Roos M., Boycott KM, Brudno M., Hurles M., Rehm HL, Matern A., Fiume M., and Sherry ST PLoS genetics, 2016/01/01, Volume 12, Issue 1, p.e1005772, (2016) Read More / View Supplemental Materials
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Development of Soft Tissue Sarcomas in Ribosomal Proteins L5 and S24 Heterozygous Mice.Kazerounian, S., Ciarlini PD, Yuan D., Ghazvinian R., Alberich-Jorda M., Joshi M., Zhang H., Beggs AH, and Gazda HT Journal of Cancer, 2016/01/01, Volume 7, Issue 1, p.32-6, (2016) Read More / View Supplemental Materials
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Endoderm specification and liver development.Goessling, W., and Stainier DY Methods in cell biology, 2016/01/01, Volume 134, p.463-83, (2016) Read More / View Supplemental Materials
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Evaluation of Presumably Disease Causing SCN1A Variants in a Cohort of Common Epilepsy Syndromes.Lal, D., Reinthaler EM, Dejanovic B., May P., Thiele H., Lehesjoki AE, Schwarz G., Riesch E., Ikram MA, Duijn CM, Uitterlinden AG, Hofman A., Steinböck H., Gruber-Sedlmayr U., Neophytou B., Zara F., Hahn A., Genetic Commission of the Italian League against Epilepsy, EuroEPINOMICS CoGIE Consortium, Gormley P., et al. PloS one, 2016/01/01, Volume 11, Issue 3, p.e0150426, (2016) Read More / View Supplemental Materials
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Functional Implications of Human-Specific Changes in Great Ape microRNAs.Gallego, A., Melé M., Balcells I., García-Ramallo E., Torruella-Loran I., Fernández-Bellon H., Abelló T., Kondova I., Bontrop R., Hvilsom C., Navarro A., Marquès-Bonet T., and Espinosa-Parrilla Y. PloS one, 2016/01/01, Volume 11, Issue 4, p.e0154194, (2016) Read More / View Supplemental Materials
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Glutamate Receptors in Alzheimer's Disease: Mechanisms and Therapies.Anggono, V., Tsai LH, and Götz J. Neural plasticity, 2016/01/01, Volume 2016, p.8256196, (2016) Read More / View Supplemental Materials
High Throughput Screen for Escherichia coli Twin Arginine Translocation (Tat) Inhibitors.Bageshwar, UK, VerPlank L., Baker D., Dong W., Hamsanathan S., Whitaker N., Sacchettini JC, and Musser SM PloS one, 2016/01/01, Volume 11, Issue 2, p.e0149659, (2016) Read More / View Supplemental Materials
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High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA.Poulsen, JB, Lescai F., Grove J., Bækvad-Hansen M., Christiansen M., Hagen CM, Maller J., Stevens C., Li S., Li Q., Sun J., Wang J., Nordentoft M., Werge TM, Mortensen PB, Børglum AD, Daly M., Hougaard DM, Bybjerg-Grauholm J., and Hollegaard MV PloS one, 2016/01/01, Volume 11, Issue 4, p.e0153253, (2016) Read More / View Supplemental Materials
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Impact of Stress on the Brain: Pathology, Treatment and Prevention.Ressler, KJ, and Smoller JW Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016/01/01, Volume 41, Issue 1, p.1-2, (2016) Read More / View Supplemental Materials
An Improved microRNA Annotation of the Canine Genome.Penso-Dolfin, L., Swofford R., Johnson J., Alföldi J., Lindblad-Toh K., Swarbreck D., Moxon S., and Di Palma F. PloS one, 2016/01/01, Volume 11, Issue 4, p.e0153453, (2016) Read More / View Supplemental Materials
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Investigation of Genetic Variation Underlying Central Obesity amongst South Asians.Scott, WR, Zhang W., Loh M., Tan ST, Lehne B., Afzal U., Peralta J., Saxena R., Ralhan S., Wander GS, Bozaoglu K., Sanghera DK, Elliott P., Scott J., Chambers JC, and Kooner JS PloS one, 2016/01/01, Volume 11, Issue 5, p.e0155478, (2016) Read More / View Supplemental Materials
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Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes.Ho, JE, Larson MG, Ghorbani A., Cheng S., Chen MH, Keyes M., Rhee EP, Clish CB, Vasan RS, Gerszten RE, and Wang TJ PloS one, 2016/01/01, Volume 11, Issue 2, p.e0148361, (2016) Read More / View Supplemental Materials
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MiR-449a Affects Epithelial Proliferation during the Pseudoglandular and Canalicular Phases of Avian and Mammal Lung Development.Sanford, EL, Choy KW, Donahoe PK, Tracy AA, Hila R., Loscertales M., and Longoni M. PloS one, 2016/01/01, Volume 11, Issue 2, p.e0149425, (2016) Read More / View Supplemental Materials
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Multiplexed Immunoaffinity Enrichment of Peptides with Anti-peptide Antibodies and Quantification by Stable Isotope Dilution Multiple Reaction Monitoring Mass Spectrometry.Kuhn, E., and Carr SA Methods in molecular biology (Clifton, N.J.), 2016/01/01, Volume 1410, p.135-67, (2016) Read More / View Supplemental Materials
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Neoepitopes and CD3-Positive and CD8-Positive Cells in Polymerase e-Mutated and Microsatellite-Instable Endometrial Cancers-Reply.Howitt, BE, Shukla SA, and Konstantinopoulos PA JAMA oncology, 2016/01/01, Volume 2, Issue 1, p.141-2, (2016) Read More / View Supplemental Materials
PhyloPythiaS+: a self-training method for the rapid reconstruction of low-ranking taxonomic bins from metagenomes.Gregor, I., Dröge J., Schirmer M., Quince C., and McHardy AC PeerJ, 2016/01/01, Volume 4, p.e1603, (2016) Read More / View Supplemental Materials
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Recommendations for open data science.Gymrek, M., and Farjoun Y. GigaScience, 2016/01/01, Volume 5, p.22, (2016) Read More / View Supplemental Materials
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Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry-Based Assays.Hoofnagle, AN, Whiteaker JR, Carr SA, Kuhn E., Liu T., Massoni SA, Thomas SN, Townsend RR, Zimmerman LJ, Boja E., Chen J., Crimmins DL, Davies SR, Gao Y., Hiltke TR, Ketchum KA, Kinsinger CR, Mesri M., Meyer MR, Qian WJ, et al. Clinical chemistry, 2016/01/01, Volume 62, Issue 1, p.48-69, (2016) Read More / View Supplemental Materials
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Reconstruction and Analysis of the Evolution of Modular Transcriptional Regulatory Programs Using Arboretum.Knaack, SA, Thompson DA, and Roy S. Methods in molecular biology (Clifton, N.J.), 2016/01/01, Volume 1361, p.375-89, (2016) Read More / View Supplemental Materials
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Simulating Serial-Target Antibacterial Drug Synergies Using Flux Balance Analysis.Krueger, AS, Munck C., Dantas G., Church GM, Galagan J., Lehár J., and Sommer MO PloS one, 2016/01/01, Volume 11, Issue 1, p.e0147651, (2016) Read More / View Supplemental Materials
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Total and Differential Leukocyte Counts in Relation to Incidence of Diabetes Mellitus: A Prospective Population-Based Cohort Study.Borné, Y., Smith JG, Nilsson PM, Melander O., Hedblad B., and Engström G. PloS one, 2016/01/01, Volume 11, Issue 2, p.e0148963, (2016) Read More / View Supplemental Materials
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Using the CPTAC Assay Portal to Identify and Implement Highly Characterized Targeted Proteomics Assays.Whiteaker, JR, Halusa GN, Hoofnagle AN, Sharma V., Maclean B., Yan P., Wrobel JA, Kennedy J., Mani D. R., Zimmerman LJ, Meyer MR, Mesri M., Boja E., Carr SA, Chan DW, Chen X., Chen J., Davies SR, Ellis MJ, Fenyö D., et al. Methods in molecular biology (Clifton, N.J.), 2016/01/01, Volume 1410, p.223-36, (2016) Read More / View Supplemental Materials
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Whole Genome Sequencing of Mycobacterium africanum Strains from Mali Provides Insights into the Mechanisms of Geographic Restriction.Winglee, K., Manson McGuire A., Maiga M., Abeel T., Shea T., Desjardins CA, Diarra B., Baya B., Sanogo M., Diallo S., Earl AM, and Bishai WR PLoS neglected tropical diseases, 2016/01/01, Volume 10, Issue 1, p.e0004332, (2016) Read More / View Supplemental Materials
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2015
In vivo gene editing in dystrophic mouse muscle and muscle stem cells.Tabebordbar, M., Zhu K., Cheng JK, Chew WL, Widrick JJ, Yan WX, Maesner C., Wu EY, Xiao R., Ran FA, Cong L., Zhang F., Vandenberghe LH, Church GM, and Wagers AJ Science (New York, N.Y.), 2015/12/31, (2015) Read More / View Supplemental Materials
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In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.Nelson, CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Rivera RM, Madhavan S., Pan X., Ran FA, Yan WX, Asokan A., Zhang F., Duan D., and Gersbach CA Science (New York, N.Y.), 2015/12/31, (2015) Read More / View Supplemental Materials
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Mutations in HSPB8 causing a new phenotype of distal myopathy and motor neuropathy.Ghaoui, R., Palmio J., Brewer J., Lek M., Needham M., Evilä A., Hackman P., Jonson PH, Penttilä S., Vihola A., Huovinen S., Lindfors M., Davis RL, Waddell L., Kaur S., Yiannikas C., North K., Clarke N., Macarthur DG, Sue CM, et al. Neurology, 2015/12/30, (2015) Read More / View Supplemental Materials
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Sustained Akt activity is required to maintain cell viability in seborrheic keratosis, a benign epithelial tumor.Neel, VA, Todorova K., Wang J., Kwon E., Kang M., Liu Q., Gray N., Lee SW, and Mandinova A. The Journal of investigative dermatology, 2015/12/28, (2015) Read More / View Supplemental Materials
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Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.Burak, MF, Inouye KE, White A., Lee A., Tuncman G., Calay ES, Sekiya M., Tirosh A., Eguchi K., Birrane G., Lightwood D., Howells L., Odede G., Hailu H., West S., Garlish R., Neale H., Doyle C., Moore A., and Hotamisligil GS Science translational medicine, 2015/12/23, Volume 7, Issue 319, p.319ra205, (2015) Read More / View Supplemental Materials
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High density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fraction.McClay, JL, Shabalin AA, Dozmorov MG, Adkins DE, Kumar G., Nerella S., Clark SL, Bergen SE, Swedish Schizophrenia Consortium, Hultman CM, Magnusson PK, Sullivan PF, Aberg KA, and van den Oord EJ Genome biology, 2015/12/23, Volume 16, Issue 1, p.291, (2015) Read More / View Supplemental Materials
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Insulator dysfunction and oncogene activation in IDH mutant gliomas.Flavahan, WA, Drier Y., Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, and Bernstein BE Nature, 2015/12/23, (2015) Read More / View Supplemental Materials
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The Molecular Signatures Database (MSigDB) hallmark gene set collection.Liberzon, A., Birger C., Thorvaldsdóttir H., Ghandi M., Mesirov J. P., and Tamayo P. Cell systems, 2015/12/23, Volume 1, Issue 6, p.417-425, (2015) Read More / View Supplemental Materials
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Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F.Shaw, AT, Friboulet L., Leshchiner I., Gainor JF, Bergqvist S., Brooun A., Burke BJ, Deng YL, Liu W., Dardaei L., Frias RL, Schultz KR, Logan J., James LP, Smeal T., Timofeevski S., Katayama R., Iafrate AJ, Le L., McTigue M., et al. The New England journal of medicine, 2015/12/23, (2015) Read More / View Supplemental Materials
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Targetable genetic features of primary testicular and primary central nervous system lymphomas.Chapuy, B., Roemer MG, Stewart C., Tan Y., Abo RP, Zhang L., Dunford AJ, Meredith DM, Thorner AR, Jordanova ES, Liu G., Feuerhake F., Ducar MD, Illerhaus G., Gusenleitner D., Linden EA, Sun HH, Homer H., Aono M., Pinkus GS, et al. Blood, 2015/12/23, (2015) Read More / View Supplemental Materials
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The metabolic fingerprint of p,p'-DDE and HCB exposure in humans.Salihovic, S., Ganna A., Fall T., Broeckling CD, Prenni JE, van Bavel B., Lind PM, Ingelsson E., and Lind L. Environment international, 2015/12/22, Volume 88, p.60-66, (2015) Read More / View Supplemental Materials
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RECQL5 Suppresses Oncogenic JAK2-Induced Replication Stress and Genomic Instability.Chen, E., Ahn JS, Sykes DB, Breyfogle LJ, Godfrey AL, Nangalia J., Ko A., DeAngelo DJ, Green AR, and Mullally A. Cell reports, 2015/12/22, Volume 13, Issue 11, p.2345-52, (2015) Read More / View Supplemental Materials
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Tools for the Microbiome: Nano and Beyond.Biteen, JS, Blainey PC, Cardon ZG, Chun M., Church GM, Dorrestein PC, Fraser SE, Gilbert JA, Jansson JK, Knight R., Miller JF, Ozcan A., Prather KA, Quake SR, Ruby EG, Silver PA, Taha S., van den Engh G., Weiss PS, Wong GC, et al. ACS nano, 2015/12/22, (2015) Read More / View Supplemental Materials
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Genetic and Epigenetic Variation, but Not Diet, Shape the Sperm Methylome.Shea, JM, Serra RW, Carone BR, Shulha HP, Kucukural A., Ziller MJ, Vallaster MP, Gu H., Tapper AR, Gardner PD, Meissner A., Garber M., and Rando OJ Developmental cell, 2015/12/21, Volume 35, Issue 6, p.750-8, (2015) Read More / View Supplemental Materials
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Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.Okosun, J., Wolfson RL, Wang J., Araf S., Wilkins L., Castellano BM, Escudero-Ibarz L., Al Seraihi AF, Richter J., Bernhart SH, Efeyan A., Iqbal S., Matthews J., Clear A., Guerra-Assunção JA, Bödör C., Quentmeier H., Mansbridge C., Johnson P., Davies A., et al. Nature genetics, 2015/12/21, (2015) Read More / View Supplemental Materials
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Regulatory mutations in TBX3 disrupt asymmetric hair pigmentation that underlies Dun camouflage color in horses.Imsland, F., McGowan K., Rubin CJ, Henegar C., Sundström E., Berglund J., Schwochow D., Gustafson U., Imsland P., Lindblad-Toh K., Lindgren G., Mikko S., Millon L., Wade C., Schubert M., Orlando L., Penedo MC, Barsh GS, and Andersson L. Nature genetics, 2015/12/21, (2015) Read More / View Supplemental Materials
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Many lncRNAs, 5'UTRs, and pseudogenes are translated and some are likely to express functional proteins.Ji, Z., Song R., Regev A., and Struhl K. eLife, 2015/12/19, Volume 4, (2015) Read More / View Supplemental Materials
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Analysis of the ACTN3 Heterozygous Genotype Suggests That α-Actinin-3 Controls Sarcomeric Composition and Muscle Function in a Dose-Dependent Fashion.Hogarth, MW, Garton FC, Houweling PJ, Tukiainen T., Lek M., Macarthur DG, Seto JT, Quinlan KG, Yang N., Head SI, and North KN Human molecular genetics, 2015/12/17, (2015) Read More / View Supplemental Materials
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Structural Basis of Neurohormone Perception by the Receptor Tyrosine Kinase Torso.Jenni, S., Goyal Y., von Grotthuss M., Shvartsman SY, and Klein DE Molecular cell, 2015/12/17, Volume 60, Issue 6, p.941-52, (2015) Read More / View Supplemental Materials
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Evidence of Common Genetic Overlap Between Schizophrenia and Cognition.Hubbard, L., Tansey KE, Rai D., Jones P., Ripke S., Chambert KD, Moran JL, McCarroll SA, Linden DE, Owen MJ, O'Donovan MC, Walters JT, and Zammit S. Schizophrenia bulletin, 2015/12/16, (2015) Read More / View Supplemental Materials
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JAKMIP1: Translating the Message for Social Behavior.Penney, J., and Tsai LH Neuron, 2015/12/16, Volume 88, Issue 6, p.1070-2, (2015) Read More / View Supplemental Materials
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Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR.Li, W., Köster J., Xu H., Chen CH, Xiao T., Liu JS, Brown M., and Liu XS Genome biology, 2015/12/16, Volume 16, Issue 1, p.281, (2015) Read More / View Supplemental Materials
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Reply to Melillo: Woranso-Mille is consistent with an australopithecine shoulder intermediate between African apes and Homo.Young, NM, Capellini TD, Roach NT, and Alemseged Z. Proceedings of the National Academy of Sciences of the United States of America, 2015/12/16, (2015) Read More / View Supplemental Materials
Genome-wide association study of 25(OH) Vitamin D concentrations in Punjabi Sikhs: Results of the Asian Indian diabetic heart study.Sapkota, BR, Hopkins R., Bjonnes A., Ralhan S., Wander GS, Mehra NK, Singh JR, Blackett PR, Saxena R., and Sanghera DK The Journal of steroid biochemistry and molecular biology, 2015/12/15, (2015) Read More / View Supplemental Materials
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A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder.Sellgren, CM, Kegel ME, Bergen SE, Ekman CJ, Olsson S., Larsson M., Vawter MP, Backlund L., Sullivan PF, Sklar P., Smoller JW, Magnusson PK, Hultman CM, Walther-Jallow L., Svensson CI, Lichtenstein P., Schalling M., Engberg G., Erhardt S., and Landén M. Molecular psychiatry, 2015/12/15, (2015) Read More / View Supplemental Materials
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Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip.Kim, HJ, Li H., Collins JJ, and Ingber DE Proceedings of the National Academy of Sciences of the United States of America, 2015/12/14, (2015) Read More / View Supplemental Materials
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Correlating chemical sensitivity and basal gene expression reveals mechanism of action.Rees, MG, Seashore-Ludlow B., Cheah JH, Adams DJ, Price EV, Gill S., Javaid S., Coletti ME, Jones VL, Bodycombe NE, Soule CK, Alexander B., Li A., Montgomery P., Kotz JD, Hon CS, Munoz B., Liefeld T., Dančík V., Haber DA, et al. Nature chemical biology, 2015/12/14, (2015) Read More / View Supplemental Materials
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Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.Zhang, X., Choi PS, Francis JM, Imielinski M., Watanabe H., Cherniack AD, and Meyerson M. Nature genetics, 2015/12/14, (2015) Read More / View Supplemental Materials
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TERT promoter mutations and monoallelic activation of TERT in cancer.Huang, FW, Bielski CM, Rinne ML, Hahn WC, Sellers WR, Stegmeier F., Garraway LA, and Kryukov GV Oncogenesis, 2015/12/14, Volume 4, p.e176, (2015) Read More / View Supplemental Materials
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Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness.Bigdeli, TB, Ripke S., Bacanu SA, Lee SH, Wray NR, Gejman PV, Rietschel M., Cichon S., St Clair D., Corvin A., Kirov G., McQuillin A., Gurling H., Rujescu D., Andreassen OA, Werge T., Blackwood DH, Pato CN, Pato MT, Malhotra AK, et al. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2015/12/11, (2015) Read More / View Supplemental Materials
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Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification.Logan, DJ, Shan J., Bhatia SN, and Carpenter AE Methods (San Diego, Calif.), 2015/12/11, (2015) Read More / View Supplemental Materials
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Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk.Yu, B., Pulit SL, Hwang SJ, Brody JA, Amin N., Auer PL, Bis JC, Boerwinkle E., Burke GL, Chakravarti A., Correa A., Dreisbach AW, Franco OH, Ehret GB, Franceschini N., Hofman A., Lin DY, Metcalf GA, Musani SK, Muzny D., et al. Circulation. Cardiovascular genetics, 2015/12/11, (2015) Read More / View Supplemental Materials
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Effect of growth hormone on cognitive function in young women with abdominal obesity.Bove, RM, White CC, Gerweck AV, Mancuso SM, Bredella MA, Sherman JC, and Miller KK Clinical endocrinology, 2015/12/10, (2015) Read More / View Supplemental Materials
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HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease.Ward, LD, and Kellis M. Nucleic acids research, 2015/12/10, (2015) Read More / View Supplemental Materials
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The histone chaperone CAF-1 safeguards somatic cell identity.Cheloufi, S., Elling U., Hopfgartner B., Jung YL, Murn J., Ninova M., Hubmann M., Badeaux AI, Euong Ang C., Tenen D., Wesche DJ, Abazova N., Hogue M., Tasdemir N., Brumbaugh J., Rathert P., Jude J., Ferrari F., Blanco A., Fellner M., et al. Nature, 2015/12/10, Volume 528, Issue 7581, p.218-24, (2015) Read More / View Supplemental Materials
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A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes.van Galen, P., Viny AD, Ram O., Ryan RJ, Cotton MJ, Donohue L., Sievers C., Drier Y., Liau BB, Gillespie SM, Carroll KM, Cross MB, Levine RL, and Bernstein BE Molecular cell, 2015/12/10, (2015) Read More / View Supplemental Materials
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Evolution and Spread of Ebola Virus in Liberia, 2014-2015.Ladner, JT, Wiley MR, Mate S., Dudas G., Prieto K., Lovett S., Nagle ER, Beitzel B., Gilbert ML, Fakoli L., Diclaro JW 2nd, Schoepp RJ, Fair J., Kuhn JH, Hensley LE, Park DJ, Sabeti PC, Rambaut A., Sanchez-Lockhart M., Bolay FK, et al. Cell host & microbe, 2015/12/09, Volume 18, Issue 6, p.659-69, (2015) Read More / View Supplemental Materials
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Identification and characterization of latency-associated peptide-expressing γδ T cells.Rezende, RM, da Cunha AP, Kuhn C., Rubino S., M'Hamdi H., Gabriely G., Vandeventer T., Liu S., Cialic R., Pinheiro-Rosa N., Oliveira RP, Gaublomme JT, Obholzer N., Kozubek J., Pochet N., Faria AM, and Weiner HL Nature communications, 2015/12/08, Volume 6, p.8726, (2015) Read More / View Supplemental Materials
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Abundant contribution of short tandem repeats to gene expression variation in humans.Gymrek, M., Willems T., Guilmatre A., Zeng H., Markus B., Georgiev S., Daly M. J., Price AL, Pritchard JK, Sharp AJ, and Erlich Y. Nature genetics, 2015/12/07, (2015) Read More / View Supplemental Materials
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'Deadman' and 'Passcode' microbial kill switches for bacterial containment.Chan, CT, Lee JW, Cameron DE, Bashor CJ, and Collins JJ Nature chemical biology, 2015/12/07, (2015) Read More / View Supplemental Materials
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A Generic and Cell-Type-Specific Wound Response Precedes Regeneration in Planarians.Wurtzel, O., Cote LE, Poirier A., Satija R., Regev A., and Reddien PW Developmental cell, 2015/12/07, Volume 35, Issue 5, p.632-45, (2015) Read More / View Supplemental Materials
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The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins.Li, N., Yousefi M., Nakauka-Ddamba A., Li F., Vandivier L., Parada K., Woo DH, Wang S., Naqvi AS, Rao S., Tobias J., Cedeno RJ, Minuesa G., Y K., Barlowe TS, Valvezan A., Shankar S., Deering RP, Klein PS, Jensen ST, et al. Cell reports, 2015/12/07, (2015) Read More / View Supplemental Materials
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Self-assembled RNA-triple-helix hydrogel scaffold for microRNA modulation in the tumour microenvironment.Conde, J., Oliva N., Atilano M., Song HS, and Artzi N. Nature materials, 2015/12/07, (2015) Read More / View Supplemental Materials
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Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution.Kasar, S., Kim J., Improgo R., Tiao G., Polak P., Haradhvala N., Lawrence MS, Kiezun A., Fernandes SM, Bahl S., Sougnez C., Gabriel S., Lander E. S., Kim HT, Getz G., and Brown JR Nature communications, 2015/12/07, Volume 6, p.8866, (2015) Read More / View Supplemental Materials
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Two unique TUBB3 mutations cause both CFEOM3 and malformations of cortical development.Whitman, MC, Andrews C., Chan WM, Tischfield MA, Stasheff SF, Brancati F., Ortiz-Gonzalez X., Nuovo S., Garaci F., MacKinnon SE, Hunter DG, Grant PE, and Engle EC American journal of medical genetics. Part A, 2015/12/06, (2015) Read More / View Supplemental Materials
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Genomic Instability in Human Pluripotent Stem Cells Arises from Replicative Stress and Chromosome Condensation Defects.Lamm, N., Ben-David U., Golan-Lev T., Storchová Z., Benvenisty N., and Kerem B. Cell stem cell, 2015/12/05, (2015) Read More / View Supplemental Materials
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Convergent Lines of Evidence Support LRP8 as a Susceptibility Gene for Psychosis.Li, M., Huang L., Grigoroiu-Serbanescu M., Bergen SE, Landén M., Hultman CM, Forstner AJ, Strohmaier J., Hecker J., Schulze TG, Müller-Myhsok B., Reif A., Mitchell PB, Martin NG, Cichon S., Nöthen MM, Alkelai A., Lerer B., Jamain S., Leboyer M., et al. Molecular neurobiology, 2015/12/04, (2015) Read More / View Supplemental Materials
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ENIGMA and the Individual: Predicting Factors that Affect the Brain in 35 Countries Worldwide.Thompson, PM, Andreassen OA, Arias-Vasquez A., Bearden CE, Boedhoe PS, Brouwer RM, Buckner RL, Buitelaar JK, Bulaeva KB, Cannon DM, Cohen RA, Conrod PJ, Dale AM, Deary IJ, Dennis EL, de Reus MA, Desrivieres S., Dima D., Donohoe G., Fisher SE, et al. NeuroImage, 2015/12/04, (2015) Read More / View Supplemental Materials
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Pharmacogenomic agreement between two cancer cell line data sets.Cancer Cell Line Encyclopedia, Consortium, and Genomics of Drug Sensitivity in Cancer Consortium Nature, 2015/12/03, Volume 528, Issue 7580, p.84-7, (2015) Read More / View Supplemental Materials
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A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation.Fields, AP, Rodriguez EH, Jovanovic M., Stern-Ginossar N., Haas BJ, Mertins P., Raychowdhury R., Hacohen N., Carr SA, Ingolia NT, Regev A., and Weissman JS Molecular cell, 2015/12/03, Volume 60, Issue 5, p.816-27, (2015) Read More / View Supplemental Materials
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Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems.Murray, E., Cho JH, Goodwin D., Ku T., Swaney J., Kim SY, Choi H., Park YG, Park JY, Hubbert A., McCue M., Vassallo S., Bakh N., Frosch MP, Wedeen VJ, Seung HS, and Chung K. Cell, 2015/12/03, Volume 163, Issue 6, p.1500-14, (2015) Read More / View Supplemental Materials
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Prophages of the genus Bifidobacterium as modulating agents of the infant gut microbiota.Lugli, GA, Milani C., Turroni F., Tremblay D., Ferrario C., Mancabelli L., Duranti S., Ward DV, Ossiprandi MC, Moineau S., van Sinderen D., and Ventura M. Environmental microbiology, 2015/12/02, (2015) Read More / View Supplemental Materials
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Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.D'Gama, AM, Pochareddy S., Li M., Jamuar SS, Reiff RE, Lam AT, Sestan N., and Walsh CA Neuron, 2015/12/02, Volume 88, Issue 5, p.910-7, (2015) Read More / View Supplemental Materials
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A bivariate Genome Wide Association Study (GWAS) of depressive symptoms and lipid levels has identified pleiotropic gene loci.Amare, AT, Cohorts for Heart and Aging Research in Genomic Epidemiology(CHARGE) depression working Group, Global Lipids Genetics Consortium, Nigatu YT, Hsu YH, Lahti J., Alizadeh BZ, and Snieder H. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2015/12/01, Volume 47, Issue Pt A, p.113-4, (2015) Read More / View Supplemental Materials
Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection.Mesquita, RD, Vionette-Amaral RJ, Lowenberger C., Rivera-Pomar R., Monteiro FA, Minx P., Spieth J., Carvalho AB, Panzera F., Lawson D., Torres AQ, Ribeiro JM, Sorgine MH, Waterhouse RM, Montague MJ, Abad-Franch F., Alves-Bezerra M., Amaral LR, Araujo HM, Araujo RN, et al. Proceedings of the National Academy of Sciences of the United States of America, 2015/12/01, Volume 112, Issue 48, p.14936-14941, (2015) Read More / View Supplemental Materials
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High-Specificity Targeted Functional Profiling in Microbial Communities with ShortBRED.Kaminski, J., Gibson MK, Franzosa EA, Segata N., Dantas G., and Huttenhower C. PLoS computational biology, 2015/12/01, Volume 11, Issue 12, p.e1004557, (2015) Read More / View Supplemental Materials
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Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens.March, S., Ramanan V., Trehan K., Ng S., Galstian A., Gural N., Scull MA, Shlomai A., Mota MM, Fleming HE, Khetani SR, Rice CM, and Bhatia SN Nature protocols, 2015/12/01, Volume 10, Issue 12, p.2027-53, (2015) Read More / View Supplemental Materials
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