STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability.Luo, T., Masson K., Jaffe JD, Silkworth W., Ross NT, Scherer CA, Scholl C., Fröhling S., Carr SA, Stern AM, Schreiber SL, and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2012/02/21, Volume 109, Issue 8, p.2860-5, (2012)
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Abstract
Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture.Rohland, N., and Reich D. Genome research, 2012/02/16, (2012)
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Abstract
A PIP Gets the Plasmodium Protein Export Pathway Going.Jiang, RH, and Marti M. Cell host & microbe, 2012/02/16, Volume 11, Issue 2, p.99-100, (2012)
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Abstract
Unified modeling of gene duplication, loss, and coalescence using a locus tree.Rasmussen, MD, and Kellis M. Genome research, 2012/02/16, (2012)
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Abstract
Development of small-molecule probes that selectively kill cells induced to express mutant RAS.Weïwer, M., Bittker JA, Lewis TA, Shimada K., Yang WS, Macpherson L., Dandapani S., Palmer M., Stockwell BR, Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2012/02/15, Volume 22, Issue 4, p.1822-6, (2012)
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Abstract
Modular regulatory principles of large non-coding RNAs.Guttman, M., and Rinn JL Nature, 2012/02/15, Volume 482, Issue 7385, p.339-46, (2012)
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Abstract
Genome-wide siRNA screen for mediators of NF-κB activation.Gewurz, BE, Towfic F., Mar JC, Shinners NP, Takasaki K., Zhao B., Cahir-McFarland ED, Quackenbush J., Xavier RJ, and Kieff E. Proceedings of the National Academy of Sciences of the United States of America, 2012/02/14, Volume 109, Issue 7, p.2467-72, (2012)
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Abstract
Build/Couple/Pair Strategy for the Synthesis of Stereochemically Diverse Macrolactams via Head-to-Tail Cyclization.Fitzgerald, ME, Mulrooney CA, Duvall JR, Wei J., Suh BC, Akella LB, Vrcic A., and Marcaurelle LA ACS combinatorial science, 2012/02/13, Volume 14, Issue 2, p.89-96, (2012)
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Abstract
Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria.Heidebrecht RW, Jr, Mulrooney C., Austin CP, Barker RH Jr, Beaudoin JA, Cheng KC, Comer E., Dandapani S., Dick J., Duvall JR, Ekland EH, Fidock DA, Fitzgerald ME, Foley M., Guha R., Hinkson P., Kramer M., Lukens AK, Masi D., Marcaurelle LA, et al. ACS medicinal chemistry letters, 2012/02/09, Volume 3, Issue 2, p.112-117, (2012)
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Abstract
Treatment of the respiratory distress syndrome in newborns: smoothened agonist counterbalances deleterious effects of glucocorticoids .Griveau, A. Medecine sciences : M/S, 2012/02/01, Volume 28, Issue 2, p.141-3, (2012)
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Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis.Raychaudhuri, S., Sandor C., Stahl EA, Freudenberg J., Lee HS, Jia X., Alfredsson L., Padyukov L., Klareskog L., Worthington J., Siminovitch KA, Bae SC, Plenge RM, Gregersen PK, and de Bakker PI Nature genetics, 2012/01/29, Volume 44, Issue 3, p.291-6, (2012)
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Abstract
RNA folding with soft constraints: reconciliation of probing data and thermodynamic secondary structure prediction.Washietl, S., Hofacker IL, Stadler PF, and Kellis M. Nucleic acids research, 2012/01/28, (2012)
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Abstract
The numerology of T cell functional diversity.Haining, WN Immunity, 2012/01/27, Volume 36, Issue 1, p.10-2, (2012)
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Abstract
The mystery of missing heritability: Genetic interactions create phantom heritability.Zuk, O., Hechter E., Sunyaev SR, and Lander E. S. Proceedings of the National Academy of Sciences of the United States of America, 2012/01/24, Volume 109, Issue 4, p.1193-8, (2012)
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Abstract
Human evolutionary genomics: ethical and interpretive issues.Vitti, JJ, Cho MK, Tishkoff SA, and Sabeti PC Trends in genetics : TIG, 2012/01/20, (2012)
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Abstract
Genetic variation at CR1 increases risk of cerebral amyloid angiopathy.Biffi, A., Shulman JM, Jagiella JM, Cortellini L., Ayres AM, Schwab K., Brown DL, Silliman SL, Selim M., Worrall BB, Meschia JF, Slowik A., De Jager PL, Greenberg SM, Schneider JA, Bennett DA, and Rosand J. Neurology, 2012/01/18, (2012)
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Abstract
Analyzing and minimizing PCR amplification bias in Illumina sequencing libraries.Aird, D., Ross MG, Chen WS, Danielsson M., Fennell T., Russ C., Jaffe DB, Nusbaum C., and Gnirke A. Genome biology, 2012/01/09, Volume 12, Issue 2, p.R18, (2012)
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Abstract
Assisted assembly: how to improve a de novo genome assembly by using related species.Gnerre, S., Lander E. S., Lindblad-Toh K., and Jaffe DB Genome biology, 2012/01/09, Volume 10, Issue 8, p.R88, (2012)
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Abstract
Exploiting nucleotide composition to engineer promoters.Grabherr, MG, Pontiller J., Mauceli E., Ernst W., Baumann M., Biagi T., Swofford R., Russell P., Zody MC, Di Palma F., Lindblad-Toh K., and Grabherr RM PloS one, 2012/01/09, Volume 6, Issue 5, p.e20136, (2012)
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Abstract
Extracting rich information from images.Carpenter, AE Methods in molecular biology (Clifton, N.J.), 2012/01/09, Volume 486, p.193-211, (2012)
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Abstract
The fungal genome initiative and lessons learned from genome sequencing.Cuomo, CA, and Birren BW Methods in enzymology, 2012/01/09, Volume 470, p.833-55, (2012)
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Abstract
GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers.Mermel, CH, Schumacher SE, Hill B., Meyerson ML, Beroukhim R., and Getz G. Genome biology, 2012/01/09, Volume 12, Issue 4, p.R41, (2012)
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Abstract
High-throughput real-time PCR for detection of gene-expression levels.Wagner, BK, and Arany Z. Methods in molecular biology (Clifton, N.J.), 2012/01/09, Volume 486, p.167-75, (2012)
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Abstract
Identifying cellular targets of small-molecule probes and drugs with biochemical enrichment and SILAC.Ong, SE, Li X., Schenone M., Schreiber SL, and Carr SA Methods in molecular biology (Clifton, N.J.), 2012/01/09, Volume 803, p.129-40, (2012)
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Abstract
Introduction: cell-based assays for high-throughput screening.An, WF, and Tolliday NJ Methods in molecular biology (Clifton, N.J.), 2012/01/09, Volume 486, p.1-12, (2012)
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Abstract
Large-scale identification of genetic design strategies using local search.Lun, DS, Rockwell G., Guido NJ, Baym M., Kelner JA, Berger B., Galagan JE, and Church GM Molecular systems biology, 2012/01/09, Volume 5, p.296, (2012)
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Abstract
Layout.Wong, B. Nature methods, 2012/01/09, Volume 8, Issue 10, p.783, (2012)
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Ligand discovery using small-molecule microarrays.Casalena, DE, Wassaf D., and Koehler AN Methods in molecular biology (Clifton, N.J.), 2012/01/09, Volume 803, p.249-63, (2012)
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Abstract
'Next-generation' sequencing becomes 'now-generation'.Neafsey, DE, and Haas BJ Genome biology, 2012/01/09, Volume 12, Issue 3, p.303, (2012)
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Abstract
The NIH's role in accelerating translational sciences.Reed, JC, White EL, Aubé J., Lindsley C., Li M., Sklar L., and Schreiber S. Nature biotechnology, 2012/01/09, Volume 30, Issue 1, p.16-9, (2012)
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A scalable, fully automated process for construction of sequence-ready human exome targeted capture libraries.Fisher, S., Barry A., Abreu J., Minie B., Nolan J., Delorey TM, Young G., Fennell TJ, Allen A., Ambrogio L., Berlin AM, Blumenstiel B., Cibulskis K., Friedrich D., Johnson R., Juhn F., Reilly B., Shammas R., Stalker J., Sykes SM, et al. Genome biology, 2012/01/09, Volume 12, Issue 1, p.R1, (2012)
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Abstract
Sequences to systems.Kellis, M., and Rinn JL Genome biology, 2012/01/09, Volume 11, Issue 5, p.303, (2012)
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Abstract
Strand-specific RNA sequencing reveals extensive regulated long antisense transcripts that are conserved across yeast species.Yassour, M., Pfiffner J., Levin JZ, Adiconis X., Gnirke A., Nusbaum C., Thompson DA, Friedman N., and Regev A. Genome biology, 2012/01/09, Volume 11, Issue 8, p.R87, (2012)
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Abstract
Targeted next-generation sequencing of a cancer transcriptome enhances detection of sequence variants and novel fusion transcripts.Levin, JZ, Berger MF, Adiconis X., Rogov P., Melnikov A., Fennell T., Nusbaum C., Garraway LA, and Gnirke A. Genome biology, 2012/01/09, Volume 10, Issue 10, p.R115, (2012)
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Abstract
Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence.Neafsey, DE, Schaffner SF, Volkman SK, Park D., Montgomery P., Milner DA Jr, Lukens A., Rosen D., Daniels R., Houde N., Cortese JF, Tyndall E., Gates C., Stange-Thomann N., Sarr O., Ndiaye D., Ndir O., Mboup S., Ferreira MU, Moraes Sdo L., et al. Genome biology, 2012/01/07, Volume 9, Issue 12, p.R171, (2012)
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Abstract
Complex alpha-pyrones synthesized by a gold-catalyzed coupling reaction.Luo, T., and Schreiber SL Angewandte Chemie (International ed. in English), 2012/01/06, Volume 46, Issue 43, p.8250-3, (2012)
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Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts.D'Souza, CA, Kronstad JW, Taylor G., Warren R., Yuen M., Hu G., Jung WH, Sham A., Kidd SE, Tangen K., Lee N., Zeilmaker T., Sawkins J., McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W., et al. mBio, 2012/01/06, Volume 2, Issue 1, p.e00342-10, (2012)
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Abstract
A microarray-based protocol for monitoring the growth of yeast overexpression strains.Butcher, RA, and Schreiber SL Nature protocols, 2012/01/06, Volume 1, Issue 2, p.569-76, (2012)
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Abstract
Multilevel regulation of growth rate in yeast revealed using systems biology.Ramanathan, A., and Schreiber SL Journal of biology, 2012/01/06, Volume 6, Issue 2, p.3, (2012)
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Abstract
A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC).Ong, SE, and Mann M. Nature protocols, 2012/01/06, Volume 1, Issue 6, p.2650-60, (2012)
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Abstract
Stable isotope labeling by amino acids in cell culture for quantitative proteomics.Ong, SE, and Mann M. Methods in molecular biology (Clifton, N.J.), 2012/01/06, Volume 359, p.37-52, (2012)
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Abstract
Application of natural product-inspired diversity-oriented synthesis to drug discovery.Marcaurelle, LA, and Johannes CW Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 2012/01/05, Volume 66, p.187, 189-216, (2012)
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Abstract
Cross-kingdom patterns of alternative splicing and splice recognition.McGuire, AM, Pearson MD, Neafsey DE, and Galagan JE Genome biology, 2012/01/05, Volume 9, Issue 3, p.R50, (2012)
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Abstract
Gene expression-based screening for inhibitors of PDGFR signaling.Antipova, AA, Stockwell BR, and Golub T. R. Genome biology, 2012/01/05, Volume 9, Issue 3, p.R47, (2012)
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Abstract
A transcription activator-like effector toolbox for genome engineering.Sanjana, NE, Cong L., Zhou Y., Cunniff MM, Feng G., and Zhang F. Nature protocols, 2012/01/05, Volume 7, Issue 1, p.171-92, (2012)
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Abstract
Autophagy and the immune system.Kuballa, P., Nolte WM, Castoreno AB, and Xavier RJ Annual review of immunology, 2012/01/01, Volume 30, p.611-46, (2012)
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Abstract
Bioinformatic Discovery of Bacterial Regulatory RNAs Using SIPHT.Livny, J. Methods in molecular biology (Clifton, N.J.), 2012/01/01, Volume 905, p.3-14, (2012)
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Abstract
Characterization and Robust Classification of EEG Signal from Image RSVP Events with Independent Time-Frequency Features.Meng, J., Meriño LM, Shamlo NB, Makeig S., Robbins K., and Huang Y. PloS one, 2012/01/01, Volume 7, Issue 9, p.e44464, (2012)
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Abstract
Chemical Methods to Induce Beta-Cell Proliferation.Vetere, A., and Wagner BK International journal of endocrinology, 2012/01/01, Volume 2012, p.925143, (2012)
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Abstract
A Chemical Screen Probing the Relationship between Mitochondrial Content and Cell Size.Kitami, T., Logan DJ, Negri J., Hasaka T., Tolliday NJ, Carpenter AE, Spiegelman BM, and Mootha VK PloS one, 2012/01/01, Volume 7, Issue 3, p.e33755, (2012)
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Abstract
Comparative Genome Analysis of Trichophyton rubrum and Related Dermatophytes Reveals Candidate Genes Involved in Infection.Martinez, DA, Oliver BG, Gräser Y., Goldberg JM, Li W., Martinez-Rossi NM, Monod M., Shelest E., Barton RC, Birch E., Brakhage AA, Chen Z., Gurr SJ, Heiman D., Heitman J., Kosti I., Rossi A., Saif S., Samalova M., Saunders CW, et al. mBio, 2012/01/01, Volume 3, Issue 5, (2012)
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Abstract
Correction: GW8510 Increases Insulin Expression in Pancreatic Alpha Cells through Activation of p53 Transcriptional Activity.Fomina-Yadlin, D., Kubicek S., Vetere A., Hu He KH, Schreiber SL, and Wagner BK PloS one, 2012/01/01, Volume 7, Issue 3, (2012)
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Abstract
Effects of genetic variants previously associated with fasting glucose and insulin in the diabetes prevention program.Florez, JC, Jablonski KA, McAteer JB, Franks PW, Mason CC, Mather K., Horton E., Goldberg R., Dabelea D., Kahn SE, Arakaki RF, Shuldiner AR, Knowler WC, and Diabetes Prevention Program Research Group PloS one, 2012/01/01, Volume 7, Issue 9, p.e44424, (2012)
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Abstract
GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity.Fomina-Yadlin, D., Kubicek S., Vetere A., He KH, Schreiber SL, and Wagner BK PloS one, 2012/01/01, Volume 7, Issue 1, p.e28808, (2012)
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Abstract
HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants.Ward, LD, and Kellis M. Nucleic acids research, 2012/01/01, Volume 40, Issue 1, p.D930-4, (2012)
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Abstract
High-resolution analysis of intrahost genetic diversity in dengue virus serotype 1 infection identifies mixed infections.Thai, KT, Henn MR, Zody MC, Tricou V., Nguyet NM, Charlebois P., Lennon NJ, Green L., de Vries PJ, Hien TT, Farrar J., van Doorn HR, de Jong MD, Birren BW, Holmes EC, and Simmons CP Journal of virology, 2012/01/01, Volume 86, Issue 2, p.835-43, (2012)
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Abstract
High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing.Wagle, N., Berger MF, Davis MJ, Blumenstiel B., DeFelice M., Pochanard P., Ducar M., Van Hummelen P., Macconaill LE, Hahn WC, Meyerson M., Gabriel SB, and Garraway LA Cancer discovery, 2012/01/01, Volume 2, Issue 1, p.82-93, (2012)
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Abstract
Independent Large Scale Duplications in Multiple M. tuberculosis Lineages Overlapping the Same Genomic Region.Weiner, B., Gomez J., Victor TC, Warren RM, Sloutsky A., Plikaytis BB, Posey JE, van Helden PD, Gey van Pittius NC, Koehrsen M., Sisk P., Stolte C., White J., Gagneux S., Birren B., Hung D., Murray M., and Galagan J. PloS one, 2012/01/01, Volume 7, Issue 2, p.e26038, (2012)
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Abstract
Inferring carbon sources from gene expression profiles using metabolic flux models.Brandes, A., Lun DS, Ip K., Zucker J., Colijn C., Weiner B., and Galagan JE PloS one, 2012/01/01, Volume 7, Issue 5, p.e36947, (2012)
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Abstract
Multi-Ethnic Analysis of Lipid-Associated Loci: The NHLBI CARe Project.Musunuru, K., Romaine SP, Lettre G., Wilson JG, Volcik KA, Tsai MY, Taylor HA Jr, Schreiner PJ, Rotter JI, Rich SS, Redline S., Psaty BM, Papanicolaou GJ, Ordovas JM, Liu K., Krauss RM, Glazer NL, Gabriel SB, Fornage M., Cupples LA, et al. PloS one, 2012/01/01, Volume 7, Issue 5, p.e36473, (2012)
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Abstract
Non-invasive mapping of the gastrointestinal microbiota identifies children with inflammatory bowel disease.Papa, E., Docktor M., Smillie C., Weber S., Preheim SP, Gevers D., Giannoukos G., Ciulla D., Tabbaa D., Ingram J., Schauer DB, Ward DV, Korzenik JR, Xavier RJ, Bousvaros A., and Alm EJ PloS one, 2012/01/01, Volume 7, Issue 6, p.e39242, (2012)
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Abstract
Points of view: Data exploration.Shoresh, N., and Wong B. Nature methods, 2012/01/01, Volume 9, Issue 1, p.5, (2012)
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Statistical characterization of multiple-reaction monitoring mass spectrometry (MRM-MS) assays for quantitative proteomics.Mani, D. R., Abbatiello SE, and Carr SA BMC bioinformatics, 2012/01/01, Volume 13 Suppl 16, p.S9, (2012)
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Abstract
Three-dimensional genome architecture influences partner selection for chromosomal translocations in human disease.Engreitz, JM, Agarwala V., and Mirny LA PloS one, 2012/01/01, Volume 7, Issue 9, p.e44196, (2012)
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Abstract
Quantitative assessment of ChIP-grade antbodies directed against histone modifications reveals patterns of co-occurring marks on histone protein moleculesPeach, Sally E., Rudomin Emily L., Udeshi Namrata D., Carr Steven A., and Jaffe Jacob D. Molecular & Cellular Proteomics, (2012)
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Abstract
