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2016
Molecular sled sequences are common in mammalian proteins.Xiong, K., and Blainey PC Nucleic acids research, 2016/02/08, (2016) Read More / View Supplemental Materials
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Advances in understanding erythropoiesis: evolving perspectives.Nandakumar, SK, Ulirsch JC, and Sankaran VG British journal of haematology, 2016/02/05, (2016) Read More / View Supplemental Materials
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Evidence for Unresolved γ-Ray Point Sources in the Inner Galaxy.Lee, SK, Lisanti M., Safdi BR, Slatyer TR, and Xue W. Physical review letters, 2016/02/05, Volume 116, Issue 5, p.051103, (2016) Read More / View Supplemental Materials
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The HTT CAG-Expansion Mutation Determines Age at Death but Not Disease Duration in Huntington Disease.Keum, JW, Shin A., Gillis T., Mysore JS, Abu Elneel K., Lucente D., Hadzi T., Holmans P., Jones L., Orth M., Kwak S., Macdonald ME, Gusella JF, and Lee JM American journal of human genetics, 2016/02/04, Volume 98, Issue 2, p.287-98, (2016) Read More / View Supplemental Materials
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Nuclear magnetic resonance detection and spectroscopy of single proteins using quantum logic.Lovchinsky, I., Sushkov AO, Urbach E., de Leon NP, Choi S., De Greve K., Evans R., Gertner R., Bersin E., Müller C., McGuinness L., Jelezko F., Walsworth RL, Park H., and Lukin MD Science (New York, N.Y.), 2016/02/04, (2016) Read More / View Supplemental Materials
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A Robust Example of Collider Bias in a Genetic Association Study.Day, FR, Loh PR, Scott RA, Ong KK, and Perry JR American journal of human genetics, 2016/02/04, Volume 98, Issue 2, p.392-3, (2016) Read More / View Supplemental Materials
Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut.Howitt, MR, Lavoie S., Michaud M., Blum AM, Tran SV, Weinstock JV, Gallini CA, Redding K., Margolskee RF, Osborne LC, Artis D., and Garrett WS Science (New York, N.Y.), 2016/02/04, (2016) Read More / View Supplemental Materials
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Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.Davidson, SM, Papagiannakopoulos T., Olenchock BA, Heyman JE, Keibler MA, Luengo A., Bauer MR, Jha AK, O'Brien JP, Pierce KA, Gui DY, Sullivan LB, Wasylenko TM, Subbaraj L., Chin CR, Stephanopolous G., Mott BT, Jacks T., Clish CB, and Vander Heiden MG Cell metabolism, 2016/02/03, (2016) Read More / View Supplemental Materials
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Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study.Keenan, T., Zhao W., Rasheed A., Ho WK, Malik R., Felix JF, Young R., Shah N., Samuel M., Sheikh N., Mucksavage ML, Shah O., Li J., Morley M., Laser A., Mallick NH, Zaman KS, Ishaq M., Rasheed SZ, Memon FU, et al. Journal of the American College of Cardiology, 2016/02/02, Volume 67, Issue 4, p.407-16, (2016) Read More / View Supplemental Materials
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Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs.Chen, J., Shishkin AA, Zhu X., Kadri S., Maza I., Guttman M., Hanna JH, Regev A., and Garber M. Genome biology, 2016/02/02, Volume 17, Issue 1, p.19, (2016) Read More / View Supplemental Materials
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Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis.Dubin, K., Callahan MK, Ren B., Khanin R., Viale A., Ling L., No D., Gobourne A., Littmann E., Huttenhower C., Pamer EG, and Wolchok JD Nature communications, 2016/02/02, Volume 7, p.10391, (2016) Read More / View Supplemental Materials
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Molecular sled is an eleven-amino acid vehicle facilitating biochemical interactions via sliding components along DNA.Mangel, WF, McGrath WJ, Xiong K., Graziano V., and Blainey PC Nature communications, 2016/02/02, Volume 7, p.10202, (2016) Read More / View Supplemental Materials
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Unique features of a global human ectoparasite identified through sequencing of the bed bug genome.Benoit, JB, Adelman ZN, Reinhardt K., Dolan A., Poelchau M., Jennings EC, Szuter EM, Hagan RW, Gujar H., Shukla JN, Zhu F., Mohan M., Nelson DR, Rosendale AJ, Derst C., Resnik V., Wernig S., Menegazzi P., Wegener C., Peschel N., et al. Nature communications, 2016/02/02, Volume 7, p.10165, (2016) Read More / View Supplemental Materials
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Clinical trial designs incorporating predictive biomarkers.Renfro, LA, Mallick H., An MW, Sargent DJ, and Mandrekar SJ Cancer treatment reviews, 2016/02/01, Volume 43, p.74-82, (2016) Read More / View Supplemental Materials
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Dysfunctional ADAM22 implicated in progressive encephalopathy with cortical atrophy and epilepsy.Muona, M., Fukata Y., Anttonen AK, Laari A., Palotie A., Pihko H., Lönnqvist T., Valanne L., Somer M., Fukata M., and Lehesjoki AE Neurology. Genetics, 2016/02/01, Volume 2, Issue 1, p.e46, (2016) Read More / View Supplemental Materials
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Effect of endocannabinoid degradation on pain: role of FAAH polymorphisms in experimental and postoperative pain in women treated for breast cancer.Cajanus, K., Holmström EJ, Wessman M., Anttila V., Kaunisto MA, and Kalso E. Pain, 2016/02/01, Volume 157, Issue 2, p.361-9, (2016) Read More / View Supplemental Materials
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Engineering microdeletions and microduplications by targeting segmental duplications with CRISPR.Tai, DJ, Ragavendran A., Manavalan P., Stortchevoi A., Seabra CM, Erdin S., Collins RL, Blumenthal I., Chen X., Shen Y., Sahin M., Zhang C., Lee C., Gusella JF, and Talkowski ME Nature neuroscience, 2016/02/01, (2016) Read More / View Supplemental Materials
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Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.Kilpeläinen, TO, Carli JF, Skowronski AA, Sun Q., Kriebel J., Feitosa MF, Hedman Å. K., Drong AW, Hayes JE, Zhao J., Pers TH, Schick U., Grarup N., Kutalik Z., Trompet S., Mangino M., Kristiansson K., Beekman M., Lyytikäinen LP, Eriksson J., et al. Nature communications, 2016/02/01, Volume 7, p.10494, (2016) Read More / View Supplemental Materials
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The genomic landscape of cutaneous melanoma.Zhang, T., Dutton-Regester K., Brown KM, and Hayward NK Pigment cell & melanoma research, 2016/02/01, (2016) Read More / View Supplemental Materials
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Identification of an "Exceptional Responder" Cell Line to MEK1 Inhibition: Clinical Implications for MEK-Targeted Therapy.Gannon, HS, Kaplan N., Tsherniak A., Vazquez F., Weir BA, Hahn WC, and Meyerson M. Molecular cancer research : MCR, 2016/02/01, Volume 14, Issue 2, p.207-15, (2016) Read More / View Supplemental Materials
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Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.de Waal, L., Lewis TA, Rees MG, Tsherniak A., Wu X., Choi PS, Hartigan C., Faloon PW, Hickey MJ, Tolliday N., Carr SA, Clemons PA, Munoz B., Wagner BK, Shamji AF, Koehler AN, Schenone M., Burgin AB, Schreiber SL, Greulich H., et al. Nature chemical biology, 2016/02/01, Volume 12, Issue 2, p.102-8, (2016) Read More / View Supplemental Materials
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Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression.Kløverpris, HN, Kazer SW, Mjösberg J., Mabuka JM, Wellmann A., Ndhlovu Z., Yadon MC, Nhamoyebonde S., Muenchhoff M., Simoni Y., Andersson F., Kuhn W., Garrett N., Burgers WA, Kamya P., Pretorius K., Dong K., Moodley A., Newell EW, Kasprowicz V., et al. Immunity, 2016/02/01, (2016) Read More / View Supplemental Materials
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Mechanism of Metformin: A Tale of Two Sites.Song, R. Diabetes care, 2016/02/01, Volume 39, Issue 2, p.187-9, (2016) Read More / View Supplemental Materials
Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity.Caron, A., Labbé SM, Lanfray D., Blanchard PG, Villot R., Roy C., Sabatini DM, Richard D., and Laplante M. Molecular metabolism, 2016/02/01, Volume 5, Issue 2, p.102-12, (2016) Read More / View Supplemental Materials
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Micro-electrode array recordings reveal reductions in both excitation and inhibition in cultured cortical neuron networks lacking Shank3.Lu, C., Chen Q., Zhou T., Bozic D., Fu Z., Pan JQ, and Feng G. Molecular psychiatry, 2016/02/01, Volume 21, Issue 2, p.159-68, (2016) Read More / View Supplemental Materials
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MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.Bandopadhayay, P., Ramkissoon LA, Jain P., Bergthold G., Wala J., Zeid R., Schumacher SE, Urbanski L., O'Rourke R., Gibson WJ, Pelton K., Ramkissoon SH, Han HJ, Zhu Y., Choudhari N., Silva A., Boucher K., Henn RE, Kang YJ, Knoff D., et al. Nature genetics, 2016/02/01, (2016) Read More / View Supplemental Materials
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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.Lu, Y., Day FR, Gustafsson S., Buchkovich ML, Na J., Bataille V., Cousminer DL, Dastani Z., Drong AW, Esko T., Evans DM, Falchi M., Feitosa MF, Ferreira T., Hedman Å. K., Haring R., Hysi PG, Iles MM, Justice AE, Kanoni S., et al. Nature communications, 2016/02/01, Volume 7, p.10495, (2016) Read More / View Supplemental Materials
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An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma.Drier, Y., Cotton MJ, Williamson KE, Gillespie SM, Ryan RJ, Kluk MJ, Carey CD, Rodig SJ, Sholl LM, Afrogheh AH, Faquin WC, Queimado L., Qi J., Wick MJ, El-Naggar AK, Bradner JE, Moskaluk CA, Aster J. C., Knoechel B., and Bernstein BE Nature genetics, 2016/02/01, (2016) Read More / View Supplemental Materials
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Research Letter: PTSD has shared polygenic contributions with bipolar disorder and schizophrenia in women.Sumner, JA, Duncan L., Ratanatharathorn A., Roberts AL, and Koenen KC Psychological medicine, 2016/02/01, Volume 46, Issue 3, p.669-71, (2016) Read More / View Supplemental Materials
Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition.Hata, AN, Niederst MJ, Archibald HL, Gomez-Caraballo M., Siddiqui FM, Mulvey HE, Maruvka YE, Ji F., Bhang HC, Krishnamurthy Radhakrishna V., Siravegna G., Hu H., Raoof S., Lockerman E., Kalsy A., Lee D., Keating CL, Ruddy DA, Damon LJ, Crystal AS, et al. Nature medicine, 2016/02/01, (2016) Read More / View Supplemental Materials
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The era of synthetic biology and genome engineering: Where no man has gone before.Lu, TK, Chandrasegaran S., and Hodak H. Journal of molecular biology, 2016/01/28, (2016) Read More / View Supplemental Materials
Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.Imamura, M., Takahashi A., Yamauchi T., Hara K., Yasuda K., Grarup N., Zhao W., Wang X., Huerta-Chagoya A., Hu C., Moon S., Long J., Kwak SH, Rasheed A., Saxena R., Ma RC, Okada Y., Iwata M., Hosoe J., Shojima N., et al. Nature communications, 2016/01/28, Volume 7, p.10531, (2016) Read More / View Supplemental Materials
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Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.Ceccarelli, M., Barthel FP, Malta TM, Sabedot TS, Salama SR, Murray BA, Morozova O., Newton Y., Radenbaugh A., Pagnotta SM, Anjum S., Wang J., Manyam G., Zoppoli P., Ling S., Rao AA, Grifford M., Cherniack AD, Zhang H., Poisson L., et al. Cell, 2016/01/28, Volume 164, Issue 3, p.550-63, (2016) Read More / View Supplemental Materials
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A null mutation in ANGPTL8 does not associate with either plasma glucose or type 2 diabetes in humans.Clapham, KR, Chu AY, Wessel J., Natarajan P., Flannick J., Rivas MA, Sartori S., Mehran R., Baber U., Fuster V., Scott RA, Rader DJ, Boehnke M., McCarthy MI, Altshuler DM, Kathiresan S., and Peloso GM BMC endocrine disorders, 2016/01/28, Volume 16, Issue 1, p.7, (2016) Read More / View Supplemental Materials
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Parsing the Interferon Transcriptional Network and Its Disease Associations.Mostafavi, S., Yoshida H., Moodley D., LeBoité H., Rothamel K., Raj T., Ye CJ, Chevrier N., Zhang SY, Feng T., Lee M., Casanova JL, Clark JD, Hegen M., Telliez JB, Hacohen N., De Jager PL, Regev A., Mathis D., Benoist C., et al. Cell, 2016/01/28, Volume 164, Issue 3, p.564-78, (2016) Read More / View Supplemental Materials
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Case Report: Next generation sequencing identifies a NAB2-STAT6 fusion in Glioblastoma.Diamandis, P., Ferrer-Luna R., Huang RY, Folkerth RD, Ligon AH, Wen PY, Beroukhim R., Ligon KL, and Ramkissoon SH Diagnostic pathology, 2016/01/27, Volume 11, Issue 1, p.13, (2016) Read More / View Supplemental Materials
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CP-CHARM: segmentation-free image classification made accessible.Uhlmann, V., Singh S., and Carpenter AE BMC bioinformatics, 2016/01/27, Volume 17, Issue 1, p.51, (2016) Read More / View Supplemental Materials
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Effect of Breed on Plasma Endothelin-1 Concentration, Plasma Renin Activity, and Serum Cortisol Concentration in Healthy Dogs.Höglund, K., Lequarré AS, Ljungvall I., McEntee K., Merveille AC, Wiberg M., Gouni V., Lundgren Willesen J., Hanås S., Wess G., Mejer Sørensen L., Tiret L., Kierczak M., Forsberg SK, Seppälä E., Lindblad-Toh K., Lohi H., Chetboul V., Fredholm M., and Häggström J. Journal of veterinary internal medicine / American College of Veterinary Internal Medicine, 2016/01/27, (2016) Read More / View Supplemental Materials
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Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis.Zhou, Y., Zhu G., Charlesworth JC, Simpson S Jr, Rubicz R., Göring HH, Patsopoulos NA, Laverty C., Wu F., Henders A., Ellis JJ, van der Mei I., Montgomery GW, Blangero J., Curran JE, Johnson MP, Martin NG, Nyholt DR, Taylor BV, and consortium ANZgene Multiple sclerosis (Houndmills, Basingstoke, England), 2016/01/27, (2016) Read More / View Supplemental Materials
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Higher brain BDNF gene expression is associated with slower cognitive decline in older adults.Buchman, AS, Yu L., Boyle PA, Schneider JA, De Jager PL, and Bennett DA Neurology, 2016/01/27, (2016) Read More / View Supplemental Materials
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Prominent scapulae mimicking an inherited myopathy expands the phenotype of CHD7-related disease.O'Grady, GL, Ma A., Sival D., Wong MT, Peduto T., Menezes MP, Young H., Waddell L., Ghaoui R., Needham M., Lek M., North KN, Macarthur DG, van Ravenswaaij-Arts CM, and Clarke NF European journal of human genetics : EJHG, 2016/01/27, (2016) Read More / View Supplemental Materials
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Proteogenomics: Opportunities and Caveats.Dimitrakopoulos, L., Prassas I., Diamandis EP, Nesvizhskii A., Kislinger T., Jaffe J., and Drabovich A. Clinical chemistry, 2016/01/27, (2016) Read More / View Supplemental Materials
An engineered multicomponent bone marrow niche for the recapitulation of hematopoiesis at ectopic transplantation sites.Ventura Ferreira, MS, Bergmann C., Bodensiek I., Peukert K., Abert J., Kramann R., Kachel P., Rath B., Rütten S., Knuchel R., Ebert BL, Fischer H., Brümmendorf TH, and Schneider RK Journal of hematology & oncology, 2016/01/25, Volume 9, Issue 1, p.4, (2016) Read More / View Supplemental Materials
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Toward clinical genomics in everyday medicine: perspectives and recommendations.Delaney, SK, Hultner ML, Jacob HJ, Ledbetter DH, McCarthy JJ, Ball M., Beckman KB, Belmont JW, Bloss CS, Christman MF, Cosgrove A., Damiani SA, Danis T., Delledonne M., Dougherty MJ, Dudley JT, Faucett WA, Friedman JR, Haase DH, Hays TS, et al. Expert review of molecular diagnostics, 2016/01/25, (2016) Read More / View Supplemental Materials
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Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.Pattaro, C., Teumer A., Gorski M., Chu AY, Li M., Mijatovic V., Garnaas M., Tin A., Sorice R., Li Y., Taliun D., Olden M., Foster M., Yang Q., Chen MH, Pers TH, Johnson AD, Ko YA, Fuchsberger C., Tayo B., et al. Nature communications, 2016/01/21, Volume 7, p.10023, (2016) Read More / View Supplemental Materials
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Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells.Soucie, EL, Weng Z., Geirsdóttir L., Molawi K., Maurizio J., Fenouil R., Mossadegh-Keller N., Gimenez G., VanHille L., Beniazza M., Favret J., Berruyer C., Perrin P., Hacohen N., Andrau JC, Ferrier P., Dubreuil P., Sidow A., and Sieweke MH Science (New York, N.Y.), 2016/01/21, (2016) Read More / View Supplemental Materials
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The Power of Sophisticated Phenotypic Screening and Modern Mechanism-of-Action Methods.Wagner, BK, and Schreiber SL Cell chemical biology, 2016/01/21, Volume 23, Issue 1, p.3-9, (2016) Read More / View Supplemental Materials
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Programmed Ventricular Stimulation for Risk Stratification in the Brugada Syndrome: A Pooled Analysis.Sroubek, J., Probst V., Mazzanti A., Delise P., Castro Hevia J., Ohkubo K., Zorzi A., Champagne J., Kostopoulou A., Yin X., Napolitano C., Milan DJ, Wilde A., Sacher F., Borggrefe M., Ellinor PT, Theodorakis G., Nault I., Corrado D., Watanabe I., et al. Circulation, 2016/01/21, (2016) Read More / View Supplemental Materials
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An eMERGE Clinical Center at Partners Personalized Medicine.Smoller, JW, Karlson EW, Green RC, Kathiresan S., Macarthur DG, Talkowski ME, Murphy SN, and Weiss ST Journal of personalized medicine, 2016/01/20, Volume 6, Issue 1, (2016) Read More / View Supplemental Materials
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H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs.Surface, LE, Fields PA, Subramanian V., Behmer R., Udeshi N., Peach SE, Carr SA, Jaffe JD, and Boyer LA Cell reports, 2016/01/20, (2016) Read More / View Supplemental Materials
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Information Technology Support for Clinical Genetic Testing within an Academic Medical Center.Aronson, S., Mahanta L., Ros LL, Clark E., Babb L., Oates M., Rehm H., and Lebo M. Journal of personalized medicine, 2016/01/20, Volume 6, Issue 1, (2016) Read More / View Supplemental Materials
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Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair.Haradhvala, NJ, Polak P., Stojanov P., Covington KR, Shinbrot E., Hess JM, Rheinbay E., Kim J., Maruvka YE, Braunstein LZ, Kamburov A., Hanawalt PC, Wheeler DA, Koren A., Lawrence MS, and Getz G. Cell, 2016/01/20, (2016) Read More / View Supplemental Materials
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Quantifying prion disease penetrance using large population control cohorts.Minikel, EV, Vallabh SM, Lek M., Estrada K., Samocha KE, Sathirapongsasuti JF, McLean CY, Tung JY, Yu LP, Gambetti P., Blevins J., Zhang S., Cohen Y., Chen W., Yamada M., Hamaguchi T., Sanjo N., Mizusawa H., Nakamura Y., Kitamoto T., et al. Science translational medicine, 2016/01/20, Volume 8, Issue 322, p.322ra9, (2016) Read More / View Supplemental Materials
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Compendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation.Godec, J., Tan Y., Liberzon A., Tamayo P., Bhattacharya S., Butte AJ, Mesirov J. P., and Haining WN Immunity, 2016/01/19, Volume 44, Issue 1, p.194-206, (2016) Read More / View Supplemental Materials
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Metabolic Profiling of Right Ventricular-Pulmonary Vascular Function Reveals Circulating Biomarkers of Pulmonary Hypertension.Lewis, GD, Ngo D., Hemnes AR, Farrell L., Domos C., Pappagianopoulos PP, Dhakal BP, Souza A., Shi X., Pugh ME, Beloiartsev A., Sinha S., Clish CB, and Gerszten RE Journal of the American College of Cardiology, 2016/01/19, Volume 67, Issue 2, p.174-89, (2016) Read More / View Supplemental Materials
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Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace.Qu, K., Garamszegi S., Wu F., Thorvaldsdottir H., Liefeld T., Ocana M., Borges-Rivera D., Pochet N., Robinson JT, Demchak B., Hull T., Ben-Artzi G., Blankenberg D., Barber GP, Lee BT, Kuhn RM, Nekrutenko A., Segal E., Ideker T., Reich M., et al. Nature methods, 2016/01/18, (2016) Read More / View Supplemental Materials
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Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.Doench, JG, Fusi N., Sullender M., Hegde M., Vaimberg EW, Donovan KF, Smith I., Tothova Z., Wilen C., Orchard R., Virgin HW, Listgarten J., and Root DE Nature biotechnology, 2016/01/18, (2016) Read More / View Supplemental Materials
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Disease signatures for schizophrenia and bipolar disorder using patient-derived induced pluripotent stem cells.Watmuff, B., Berkovitch SS, Huang JH, Iaconelli J., Toffel S., and Karmacharya R. Molecular and cellular neurosciences, 2016/01/14, (2016) Read More / View Supplemental Materials
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The Heroes of CRISPR.Lander, E. S. Cell, 2016/01/14, Volume 164, Issue 1-2, p.18-28, (2016) Read More / View Supplemental Materials
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Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.Felsky, D., De Jager PL, Schneider JA, Arfanakis K., Fleischman DA, Arvanitakis Z., Honer WG, Pouget JG, Mizrahi R., Pollock BG, Kennedy JL, Bennett DA, Voineskos AN, and authors of the Alzheimer’s Disease Neuroimaging Initiative Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2016/01/13, (2016) Read More / View Supplemental Materials
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High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission.Plouffe, DM, Wree M., Du AY, Meister S., Li F., Patra K., Lubar A., Okitsu SL, Flannery EL, Kato N., Tanaseichuk O., Comer E., Zhou B., Kuhen K., Zhou Y., Leroy D., Schreiber SL, Scherer CA, Vinetz J., and Winzeler EA Cell host & microbe, 2016/01/13, Volume 19, Issue 1, p.114-26, (2016) Read More / View Supplemental Materials
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Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project.Kan, M., Auer PL, Wang GT, Bucasas KL, Hooker S., Rodriguez A., Li B., Ellis J., Adrienne Cupples L., Ida Chen YD, Dupuis J., Fox CS, Gross MD, Smith JD, Heard-Costa N., Meigs JB, Pankow JS, Rotter JI, Siscovick D., Wilson JG, et al. European journal of human genetics : EJHG, 2016/01/13, (2016) Read More / View Supplemental Materials
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Actin capping protein CAPZB regulates cell morphology, differentiation, and neural crest migration in craniofacial morphogenesis.Mukherjee, K., Ishii K., Pillalamarri V., Kammin T., Atkin JF, Hickey SE, Xi QJ, Gusella JF, Talkowski ME, Morton CC, Maas RL, and Liao EC Human molecular genetics, 2016/01/11, (2016) Read More / View Supplemental Materials
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Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved vs. Reduced Ejection Fraction.Santhanakrishnan, R., Wang N., Larson MG, Magnani JW, McManus DD, Lubitz SA, Ellinor PT, Cheng S., Vasan RS, Lee DS, Wang TJ, Levy D., Benjamin EJ, and Ho JE Circulation, 2016/01/08, (2016) Read More / View Supplemental Materials
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High-Throughput Screen in Cryptococcus neoformans Identifies a Novel Molecular Scaffold That Inhibits Cell Wall Integrity Pathway Signaling.Hartland, K., Pu J., Palmer M., Dandapani S., Moquist PN, Munoz B., DiDone L., Schreiber SL, and Krysan DJ ACS infectious diseases, 2016/01/08, Volume 2, Issue 1, p.93-102, (2016) Read More / View Supplemental Materials
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Emerging Frontiers in Drug Delivery.Tibbitt, MW, Dahlman JE, and Langer R. Journal of the American Chemical Society, 2016/01/07, (2016) Read More / View Supplemental Materials
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Label-free cell cycle analysis for high-throughput imaging flow cytometry.Blasi, T., Hennig H., Summers HD, Theis FJ, Cerveira J., Patterson JO, Davies D., Filby A., Carpenter AE, and Rees P. Nature communications, 2016/01/07, Volume 7, p.10256, (2016) Read More / View Supplemental Materials
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Training the Future Leaders in Personalized Medicine.Mason-Suares, H., Sweetser DA, Lindeman NI, and Morton CC Journal of personalized medicine, 2016/01/07, Volume 6, Issue 1, (2016) Read More / View Supplemental Materials
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The (in)famous GWAS P-value threshold revisited and updated for low-frequency variants.Fadista, J., Manning AK, Florez JC, and Groop L. European journal of human genetics : EJHG, 2016/01/06, (2016) Read More / View Supplemental Materials
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A Genome-wide RNAi Screen for Microtubule Bundle Formation and Lysosome Motility Regulation in Drosophila S2 Cells.Jolly, AL, Luan CH, Dusel BE, Dunne SF, Winding M., Dixit VJ, Robins C., Saluk JL, Logan DJ, Carpenter AE, Sharma M., Dean D., Cohen AR, and Gelfand VI Cell reports, 2016/01/06, (2016) Read More / View Supplemental Materials
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Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects.Zhou, Y., Kaiser T., Monteiro P., Zhang X., Van der Goes MS, Wang D., Barak B., Zeng M., Li C., Lu C., Wells M., Amaya A., Nguyen S., Lewis M., Sanjana N., Zhou Y., Zhang M., Zhang F., Fu Z., and Feng G. Neuron, 2016/01/06, Volume 89, Issue 1, p.147-62, (2016) Read More / View Supplemental Materials
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A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages.Kimmerling, RJ, Lee Szeto G., Li JW, Genshaft AS, Kazer SW, Payer KR, de Riba Borrajo J., Blainey PC, Irvine DJ, Shalek AK, and Manalis SR Nature communications, 2016/01/06, Volume 7, p.10220, (2016) Read More / View Supplemental Materials
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Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.Hu, SS, Lin CY, He HH, Witwicki RM, Tabassum DP, Roberts JM, Janiszewska M., Jin Huh S., Liang Y., Ryan J., Doherty E., Mohammed H., Guo H., Stover DG, Ekram MB, Peluffo G., Brown J., D'Santos C., Krop IE, Dillon D., et al. Nature, 2016/01/06, (2016) Read More / View Supplemental Materials
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Role of Tet1/3 Genes and Chromatin Remodeling Genes in Cerebellar Circuit Formation.Zhu, X., Girardo D., Govek EE, John K., Mellén M., Tamayo P., Mesirov J. P., and Hatten ME Neuron, 2016/01/06, Volume 89, Issue 1, p.100-12, (2016) Read More / View Supplemental Materials
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Common Variation in Atrial Fibrillation: Navigating the Path from Genetic Association to Mechanism.Tucker, NR, Clauss S., and Ellinor PT Cardiovascular research, 2016/01/04, (2016) Read More / View Supplemental Materials
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Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry.Figueroa, JD, Middlebrooks CD, Banday AR, Ye Y., Garcia-Closas M., Chatterjee N., Koutros S., Kiemeney LA, Rafnar T., Bishop T., Barnes HF, Matullo G., Golka K., Gago-Dominguez M., Taylor J., Fletcher T., Siddiq A., Cortessis VK, Kooperberg C., Cussenot O., et al. Human molecular genetics, 2016/01/04, (2016) Read More / View Supplemental Materials
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Lipid droplets go nuclear.Farese RV, Jr, and Walther TC The Journal of cell biology, 2016/01/04, Volume 212, Issue 1, p.7-8, (2016) Read More / View Supplemental Materials
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A twin study of rheumatoid arthritis in the Japanese population.Terao, C., Ikari K., Nakayamada S., Takahashi Y., Yamada R., Ohmura K., Hashimoto M., Furu M., Ito H., Fujii T., Yoshida S., Saito K., Taniguchi A., Momohara S., Yamanaka H., Mimori T., and Matsuda F. Modern rheumatology / the Japan Rheumatism Association, 2016/01/04, p.1-22, (2016) Read More / View Supplemental Materials
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).Klionsky, DJ, Abdelmohsen K., Abe A., Abedin MJ, Abeliovich H., Acevedo Arozena A., Adachi H., Adams CM, Adams PD, Adeli K., Adhihetty PJ, Adler SG, Agam G., Agarwal R., Aghi MK, Agnello M., Agostinis P., Aguilar PV, Aguirre-Ghiso J., Airoldi EM, et al. Autophagy, 2016/01/02, Volume 12, Issue 1, p.1-222, (2016) Read More / View Supplemental Materials
Adaptive Landscape by Environment Interactions Dictate Evolutionary Dynamics in Models of Drug Resistance.Ogbunugafor, CB, Wylie CS, Diakite I., Weinreich DM, and Hartl DL PLoS computational biology, 2016/01/01, Volume 12, Issue 1, p.e1004710, (2016) Read More / View Supplemental Materials
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Applications of CRISPR-Cas systems in neuroscience.Heidenreich, M., and Zhang F. Nature reviews. Neuroscience, 2016/01/01, Volume 17, Issue 1, p.36-44, (2016) Read More / View Supplemental Materials
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Comparative Transcriptomics in Yeasts.Thompson, DA Methods in molecular biology (Clifton, N.J.), 2016/01/01, Volume 1361, p.67-76, (2016) Read More / View Supplemental Materials
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Consent Codes: Upholding Standard Data Use Conditions.Dyke, SO, Philippakis AA, Rambla De Argila J., Paltoo DN, Luetkemeier ES, Knoppers BM, Brookes AJ, Spalding JD, Thompson M., Roos M., Boycott KM, Brudno M., Hurles M., Rehm HL, Matern A., Fiume M., and Sherry ST PLoS genetics, 2016/01/01, Volume 12, Issue 1, p.e1005772, (2016) Read More / View Supplemental Materials
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Development of Soft Tissue Sarcomas in Ribosomal Proteins L5 and S24 Heterozygous Mice.Kazerounian, S., Ciarlini PD, Yuan D., Ghazvinian R., Alberich-Jorda M., Joshi M., Zhang H., Beggs AH, and Gazda HT Journal of Cancer, 2016/01/01, Volume 7, Issue 1, p.32-6, (2016) Read More / View Supplemental Materials
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Evaluation of Presumably Disease Causing SCN1A Variants in a Cohort of Common Epilepsy Syndromes.Lal, D., Reinthaler EM, Dejanovic B., May P., Thiele H., Lehesjoki AE, Schwarz G., Riesch E., Ikram MA, Duijn CM, Uitterlinden AG, Hofman A., Steinböck H., Gruber-Sedlmayr U., Neophytou B., Zara F., Hahn A., Genetic Commission of the Italian League against Epilepsy, EuroEPINOMICS CoGIE Consortium, Gormley P., et al. PloS one, 2016/01/01, Volume 11, Issue 3, p.e0150426, (2016) Read More / View Supplemental Materials
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Functional Implications of Human-Specific Changes in Great Ape microRNAs.Gallego, A., Melé M., Balcells I., García-Ramallo E., Torruella-Loran I., Fernández-Bellon H., Abelló T., Kondova I., Bontrop R., Hvilsom C., Navarro A., Marquès-Bonet T., and Espinosa-Parrilla Y. PloS one, 2016/01/01, Volume 11, Issue 4, p.e0154194, (2016) Read More / View Supplemental Materials
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High Throughput Screen for Escherichia coli Twin Arginine Translocation (Tat) Inhibitors.Bageshwar, UK, VerPlank L., Baker D., Dong W., Hamsanathan S., Whitaker N., Sacchettini JC, and Musser SM PloS one, 2016/01/01, Volume 11, Issue 2, p.e0149659, (2016) Read More / View Supplemental Materials
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High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA.Poulsen, JB, Lescai F., Grove J., Bækvad-Hansen M., Christiansen M., Hagen CM, Maller J., Stevens C., Li S., Li Q., Sun J., Wang J., Nordentoft M., Werge TM, Mortensen PB, Børglum AD, Daly M., Hougaard DM, Bybjerg-Grauholm J., and Hollegaard MV PloS one, 2016/01/01, Volume 11, Issue 4, p.e0153253, (2016) Read More / View Supplemental Materials
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Impact of Stress on the Brain: Pathology, Treatment and Prevention.Ressler, KJ, and Smoller JW Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016/01/01, Volume 41, Issue 1, p.1-2, (2016) Read More / View Supplemental Materials
An Improved microRNA Annotation of the Canine Genome.Penso-Dolfin, L., Swofford R., Johnson J., Alföldi J., Lindblad-Toh K., Swarbreck D., Moxon S., and Di Palma F. PloS one, 2016/01/01, Volume 11, Issue 4, p.e0153453, (2016) Read More / View Supplemental Materials
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Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes.Ho, JE, Larson MG, Ghorbani A., Cheng S., Chen MH, Keyes M., Rhee EP, Clish CB, Vasan RS, Gerszten RE, and Wang TJ PloS one, 2016/01/01, Volume 11, Issue 2, p.e0148361, (2016) Read More / View Supplemental Materials
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MiR-449a Affects Epithelial Proliferation during the Pseudoglandular and Canalicular Phases of Avian and Mammal Lung Development.Sanford, EL, Choy KW, Donahoe PK, Tracy AA, Hila R., Loscertales M., and Longoni M. PloS one, 2016/01/01, Volume 11, Issue 2, p.e0149425, (2016) Read More / View Supplemental Materials
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Multiplexed Immunoaffinity Enrichment of Peptides with Anti-peptide Antibodies and Quantification by Stable Isotope Dilution Multiple Reaction Monitoring Mass Spectrometry.Kuhn, E., and Carr SA Methods in molecular biology (Clifton, N.J.), 2016/01/01, Volume 1410, p.135-67, (2016) Read More / View Supplemental Materials
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Neoepitopes and CD3-Positive and CD8-Positive Cells in Polymerase e-Mutated and Microsatellite-Instable Endometrial Cancers-Reply.Howitt, BE, Shukla SA, and Konstantinopoulos PA JAMA oncology, 2016/01/01, Volume 2, Issue 1, p.141-2, (2016) Read More / View Supplemental Materials
PhyloPythiaS+: a self-training method for the rapid reconstruction of low-ranking taxonomic bins from metagenomes.Gregor, I., Dröge J., Schirmer M., Quince C., and McHardy AC PeerJ, 2016/01/01, Volume 4, p.e1603, (2016) Read More / View Supplemental Materials
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Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry-Based Assays.Hoofnagle, AN, Whiteaker JR, Carr SA, Kuhn E., Liu T., Massoni SA, Thomas SN, Townsend RR, Zimmerman LJ, Boja E., Chen J., Crimmins DL, Davies SR, Gao Y., Hiltke TR, Ketchum KA, Kinsinger CR, Mesri M., Meyer MR, Qian WJ, et al. Clinical chemistry, 2016/01/01, Volume 62, Issue 1, p.48-69, (2016) Read More / View Supplemental Materials
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Reconstruction and Analysis of the Evolution of Modular Transcriptional Regulatory Programs Using Arboretum.Knaack, SA, Thompson DA, and Roy S. Methods in molecular biology (Clifton, N.J.), 2016/01/01, Volume 1361, p.375-89, (2016) Read More / View Supplemental Materials
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Simulating Serial-Target Antibacterial Drug Synergies Using Flux Balance Analysis.Krueger, AS, Munck C., Dantas G., Church GM, Galagan J., Lehár J., and Sommer MO PloS one, 2016/01/01, Volume 11, Issue 1, p.e0147651, (2016) Read More / View Supplemental Materials
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Total and Differential Leukocyte Counts in Relation to Incidence of Diabetes Mellitus: A Prospective Population-Based Cohort Study.Borné, Y., Smith JG, Nilsson PM, Melander O., Hedblad B., and Engström G. PloS one, 2016/01/01, Volume 11, Issue 2, p.e0148963, (2016) Read More / View Supplemental Materials
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Using the CPTAC Assay Portal to Identify and Implement Highly Characterized Targeted Proteomics Assays.Whiteaker, JR, Halusa GN, Hoofnagle AN, Sharma V., Maclean B., Yan P., Wrobel JA, Kennedy J., Mani D. R., Zimmerman LJ, Meyer MR, Mesri M., Boja E., Carr SA, Chan DW, Chen X., Chen J., Davies SR, Ellis MJ, Fenyö D., et al. Methods in molecular biology (Clifton, N.J.), 2016/01/01, Volume 1410, p.223-36, (2016) Read More / View Supplemental Materials
Abstract
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