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2014
Genome Sequencing of Multiple Primary Tumors Reveals a Novel PALB2 Variant.Schrader, KA, Stratton KL, Murali R., Laitman Y., Cavallone L., Offit L., Wen YH, Thomas T., Shah S., Rau-Murthy R., Manschreck C., Salo-Mullen E., Otegbeye E., Corines M., Zhang L., Norton L., Hudis C., Klein RJ, Kauff ND, Robson M., et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014/06/30, (2014) Read More / View Supplemental Materials
CPTAC Assay Portal: a repository of targeted proteomic assays.Whiteaker, JR, Halusa GN, Hoofnagle AN, Sharma V., Maclean B., Yan P., Wrobel JA, Kennedy J., Mani D. R., Zimmerman LJ, Meyer MR, Mesri M., Rodriguez H., Clinical Proteomic Tumor Analysis Consortium(CPTAC), and Paulovich AG Nature methods, 2014/06/27, Volume 11, Issue 7, p.703-4, (2014) Read More / View Supplemental Materials
Nonhuman genetics. Genomic basis for the convergent evolution of electric organs.Gallant, JR, Traeger LL, Volkening JD, Moffett H., Chen PH, Novina CD, Phillips GN Jr, Anand R., Wells GB, Pinch M., Güth R., Unguez GA, Albert JS, Zakon HH, Samanta MP, and Sussman MR Science (New York, N.Y.), 2014/06/27, Volume 344, Issue 6191, p.1522-5, (2014) Read More / View Supplemental Materials
Abstract
Toward better understanding of artifacts in variant calling from high-coverage samples.Li, H. Bioinformatics (Oxford, England), 2014/06/27, (2014) Read More / View Supplemental Materials
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Integrated RNA and DNA sequencing improves mutation detection in low purity tumors.Wilkerson, MD, Cabanski CR, Sun W., Hoadley KA, Walter V., Mose LE, Troester MA, Hammerman PS, Parker JS, Perou CM, and Hayes DN Nucleic acids research, 2014/06/26, (2014) Read More / View Supplemental Materials
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Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.Vimaleswaran, KS, Cavadino A., Berry DJ, investigators LifeLines Cohort Study, Jorde R., Dieffenbach AK, Lu C., Alves AC, Heerspink HJ, Tikkanen E., Eriksson J., Wong A., Mangino M., Jablonski KA, Nolte IM, Houston DK, Ahluwalia TS, van der Most PJ, Pasko D., Zgaga L., et al. The lancet. Diabetes & endocrinology, 2014/06/25, (2014) Read More / View Supplemental Materials
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Mutational Signatures in Helicobacter pylori-induced Gastric Cancer: Lessons From New Sequencing Technologies.Derks, S., and Bass AJ Gastroenterology, 2014/06/25, (2014) Read More / View Supplemental Materials
Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations.Fridman, O., Goldberg A., Ronin I., Shoresh N., and Balaban NQ Nature, 2014/06/25, (2014) Read More / View Supplemental Materials
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Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5' Sites.Schwartz, S., Mumbach MR, Jovanovic M., Wang T., Maciag K., Bushkin GG, Mertins P., Ter-Ovanesyan D., Habib N., Cacchiarelli D., Sanjana NE, Freinkman E., Pacold ME, Satija R., Mikkelsen TS, Hacohen N., Zhang F., Carr SA, Lander E. S., and Regev A. Cell reports, 2014/06/25, (2014) Read More / View Supplemental Materials
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Knockdown of Malic Enzyme 2 Suppresses Lung Tumor Growth, Induces Differentiation and Impacts PI3K/AKT Signaling.Ren, JG, Seth P., Clish CB, Lorkiewicz PK, Higashi RM, Lane AN, Fan TW, and Sukhatme VP Scientific reports, 2014/06/24, Volume 4, p.5414, (2014) Read More / View Supplemental Materials
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Altered translation of GATA1 in Diamond-Blackfan anemia.Ludwig, LS, Gazda HT, Eng JC, Eichhorn SW, Thiru P., Ghazvinian R., George TI, Gotlib JR, Beggs AH, Sieff CA, Lodish HF, Lander E. S., and Sankaran VG Nature medicine, 2014/06/22, (2014) Read More / View Supplemental Materials
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Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics.Lundby, A., Rossin EJ, Steffensen AB, Acha MR, Newton-Cheh C., Pfeufer A., Lynch SN, The QT Interval International GWAS Consortium(QT-IGC), Olesen SP, Brunak S., Ellinor PT, Jukema JW, Trompet S., Ford I., Macfarlane PW, Krijthe BP, Hofman A., Uitterlinden AG, Stricker BH, Nathoe HM, et al. Nature methods, 2014/06/22, (2014) Read More / View Supplemental Materials
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Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing.Heckl, D., Kowalczyk MS, Yudovich D., Belizaire R., Puram RV, McConkey ME, Thielke A., Aster J. C., Regev A., and Ebert BL Nature biotechnology, 2014/06/22, (2014) Read More / View Supplemental Materials
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Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.Arking, DE, Pulit SL, Crotti L., van der Harst P., Munroe PB, Koopmann TT, Sotoodehnia N., Rossin EJ, Morley M., Wang X., Johnson AD, Lundby A., Gudbjartsson DF, Noseworthy PA, Eijgelsheim M., Bradford Y., Tarasov KV, Dörr M., Müller-Nurasyid M., Lahtinen AM, et al. Nature genetics, 2014/06/22, (2014) Read More / View Supplemental Materials
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A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy.Kuiper, JJ, van Setten J., Ripke S., Van't Slot R., Mulder F., Missotten T., Baarsma GS, Francioli LC, Pulit SL, de Kovel CG, Ten Dam-van Loon N., den Hollander AI, Huis In Het Veld P., Hoyng CB, Cordero-Coma M., Martín J., Llorenç V., Arya B., Thomas D., Bakker SC, et al. Human molecular genetics, 2014/06/22, (2014) Read More / View Supplemental Materials
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Targeting transcription regulation in cancer with a covalent CDK7 inhibitor.Kwiatkowski, N., Zhang T., Rahl PB, Abraham BJ, Reddy J., Ficarro SB, Dastur A., Amzallag A., Ramaswamy S., Tesar B., Jenkins CE, Hannett NM, McMillin D., Sanda T., Sim T., Kim ND, Look T., Mitsiades CS, Weng AP, Brown JR, et al. Nature, 2014/06/22, (2014) Read More / View Supplemental Materials
Abstract
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma.Patel, AP, Tirosh I., Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H., Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O., Suvà ML, Regev A., and Bernstein BE Science (New York, N.Y.), 2014/06/20, Volume 344, Issue 6190, p.1396-401, (2014) Read More / View Supplemental Materials
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Functional Divergence of the MiRNA Transcriptome at the Onset of Drosophila Metamorphosis.Yeh, SD, von Grotthuss M., Gandasetiawan KA, Jayasekera S., Xia XQ, Chan C., Jayaswal V., and Ranz JM Molecular biology and evolution, 2014/06/19, (2014) Read More / View Supplemental Materials
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Inflammatory Bowel Disease as a Model for Translating the Microbiome.Huttenhower, C., Kostic AD, and Xavier RJ Immunity, 2014/06/19, Volume 40, Issue 6, p.843-854, (2014) Read More / View Supplemental Materials
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Metabolite Traits and Genetic Risk Provide Complementary Information for the Prediction of Future Type 2 Diabetes.Walford, GA, Porneala BC, Dauriz M., Vassy JL, Cheng S., Rhee EP, Wang TJ, Meigs JB, Gerszten RE, and Florez JC Diabetes care, 2014/06/19, (2014) Read More / View Supplemental Materials
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Single-cell RNA-seq reveals dynamic paracrine control of cellular variation.Shalek, AK, Satija R., Shuga J., Trombetta JJ, Gennert D., Lu D., Chen P., Gertner RS, Gaublomme JT, Yosef N., Schwartz S., Fowler B., Weaver S., Wang J., Wang X., Ding R., Raychowdhury R., Friedman N., Hacohen N., Park H., et al. Nature, 2014/06/19, Volume 509, Issue 7505, p.363-9, (2014) Read More / View Supplemental Materials
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Discovery of new glomerular disease-relevant genes by translational profiling of podocytes in vivo.Grgic, I., Hofmeister AF, Genovese G., Bernhardy AJ, Sun H., Maarouf OH, Bijol V., Pollak MR, and Humphreys BD Kidney international, 2014/06/18, (2014) Read More / View Supplemental Materials
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Improving accuracy of rare variant imputation with a two-step imputation approach.Kreiner-Møller, E., Medina-Gomez C., Uitterlinden AG, Rivadeneira F., and Estrada K. European journal of human genetics : EJHG, 2014/06/18, (2014) Read More / View Supplemental Materials
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Evidence of Extensive DNA Transfer between Bacteroidales Species within the Human Gut.Coyne, MJ, Zitomersky NL, McGuire AM, Earl AM, and Comstock LE mBio, 2014/06/17, Volume 5, Issue 3, (2014) Read More / View Supplemental Materials
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KRAS and YAP1 Converge to Regulate EMT and Tumor Survival.Shao, DD, Xue W., Krall EB, Bhutkar A., Piccioni F., Wang X., Schinzel AC, Sood S., Rosenbluh J., Kim JW, Zwang Y., Roberts TM, Root DE, Jacks T., and Hahn WC Cell, 2014/06/17, (2014) Read More / View Supplemental Materials
Abstract
An arp2/3 nucleated f-actin shell fragments nuclear membranes at nuclear envelope breakdown in starfish oocytes.Mori, M., Somogyi K., Kondo H., Monnier N., Falk HJ, Machado P., Bathe M., Nédélec F., and Lénárt P. Current biology : CB, 2014/06/16, Volume 24, Issue 12, p.1421-8, (2014) Read More / View Supplemental Materials
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JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer.Yamamoto, S., Wu Z., Russnes HG, Takagi S., Peluffo G., Vaske C., Zhao X., Moen Vollan HK, Maruyama R., Ekram MB, Sun H., Kim JH, Carver K., Zucca M., Feng J., Almendro V., Bessarabova M., Rueda OM, Nikolsky Y., Caldas C., et al. Cancer cell, 2014/06/16, Volume 25, Issue 6, p.762-77, (2014) Read More / View Supplemental Materials
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MDS Is a Stem Cell Disorder After All.Jaiswal, S., and Ebert BL Cancer cell, 2014/06/16, Volume 25, Issue 6, p.713-4, (2014) Read More / View Supplemental Materials
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Pareto-optimal phylogenetic tree reconciliation.Libeskind-Hadas, R., Wu YC, Bansal MS, and Kellis M. Bioinformatics (Oxford, England), 2014/06/15, Volume 30, Issue 12, p.i87-i95, (2014) Read More / View Supplemental Materials
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Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population.Consortium, SIGMA Type Diabetes 2, Estrada K., Aukrust I., Bjørkhaug L., Burtt NP, Mercader JM, García-Ortiz H., Huerta-Chagoya A., Moreno-Macías H., Walford G., Flannick J., Williams AL, Gómez-Vázquez MJ, Fernandez-Lopez JC, Martínez-Hernández A., Centeno-Cruz F., Mendoza-Caamal E., Revilla-Monsalve C., Islas-Andrade S., Córdova EJ, et al. JAMA : the journal of the American Medical Association, 2014/06/11, Volume 311, Issue 22, p.2305-14, (2014) Read More / View Supplemental Materials
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Comprehensive mutational scanning of a kinase in vivo reveals substrate-dependent fitness landscapes.Melnikov, A., Rogov P., Wang L., Gnirke A., and Mikkelsen TS Nucleic acids research, 2014/06/09, (2014) Read More / View Supplemental Materials
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Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences.Pugh, TJ, Yu W., Yang J., Field AL, Ambrogio L., Carter SL, Cibulskis K., Giannikopoulos P., Kiezun A., Kim J., McKenna A., Nickerson E., Getz G., Hoffher S., Messinger YH, Dehner LP, Roberts CW, Rodriguez-Galindo C., Williams GM, Rossi CT, et al. Oncogene, 2014/06/09, (2014) Read More / View Supplemental Materials
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Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells.Wang, J., Mikse O., Liao RG, Li Y., Tan L., Janne PA, Gray NS, Wong KK, and Hammerman PS Oncogene, 2014/06/09, (2014) Read More / View Supplemental Materials
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PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling.Moody, SE, Schinzel AC, Singh S., Izzo F., Strickland MR, Luo L., Thomas SR, Boehm JS, Kim SY, Wang ZC, and Hahn WC Oncogene, 2014/06/09, (2014) Read More / View Supplemental Materials
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Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types.Li, Q., Stram A., Chen C., Kar S., Gayther S., Pharoah P., Haiman C., Stranger B., Kraft P., and Freedman ML Human molecular genetics, 2014/06/06, (2014) Read More / View Supplemental Materials
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LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures.Duan, Q., Flynn C., Niepel M., Hafner M., Muhlich JL, Fernandez NF, Rouillard AD, Tan CM, Chen EY, Golub T. R., Sorger PK, Subramanian A., and Ma'ayan A. Nucleic acids research, 2014/06/06, (2014) Read More / View Supplemental Materials
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Selection of unique Escherichia coli clones by random amplified polymorphic DNA (RAPD): Evaluation by whole genome sequencing.Nielsen, KL, Godfrey PA, Stegger M., Andersen PS, Feldgarden M., and Frimodt-Møller N. Journal of microbiological methods, 2014/06/06, (2014) Read More / View Supplemental Materials
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Development and Applications of CRISPR-Cas9 for Genome Engineering.Hsu, PD, Lander E. S., and Zhang F. Cell, 2014/06/05, Volume 157, Issue 6, p.1262-1278, (2014) Read More / View Supplemental Materials
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Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.Kiskinis, E., Sandoe J., Williams LA, Boulting GL, Moccia R., Wainger BJ, Han S., Peng T., Thams S., Mikkilineni S., Mellin C., Merkle FT, Davis-Dusenbery BN, Ziller M., Oakley D., Ichida J., Di Costanzo S., Atwater N., Maeder ML, Goodwin MJ, et al. Cell stem cell, 2014/06/05, Volume 14, Issue 6, p.781-95, (2014) Read More / View Supplemental Materials
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Transcriptional consequences of 16p11.2 deletion and duplication in mouse cortex and multiplex autism families.Blumenthal, I., Ragavendran A., Erdin S., Klei L., Sugathan A., Guide JR, Manavalan P., Zhou JQ, Wheeler VC, Levin JZ, Ernst C., Roeder K., Devlin B., Gusella JF, and Talkowski ME American journal of human genetics, 2014/06/05, Volume 94, Issue 6, p.870-83, (2014) Read More / View Supplemental Materials
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Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'Deelen, P., Menelaou A., van Leeuwen EM, Kanterakis A., van Dijk F., Medina-Gomez C., Francioli LC, Hottenga JJ, Karssen LC, Estrada K., Kreiner-Møller E., Rivadeneira F., van Setten J., Gutierrez-Achury J., Westra HJ, Franke L., van Enckevort D., Dijkstra M., Byelas H., van Duijn CM, et al. European journal of human genetics : EJHG, 2014/06/04, (2014) Read More / View Supplemental Materials
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MIR137 variants identified in psychiatric patients affect synaptogenesis and neuronal transmission gene sets.Strazisar, M., Cammaerts S., van der Ven K., Forero DA, Lenaerts AS, Nordin A., Almeida-Souza L., Genovese G., Timmerman V., Liekens A., De Rijk P., Adolfsson R., Callaerts P., and Del-Favero J. Molecular psychiatry, 2014/06/03, (2014) Read More / View Supplemental Materials
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SMASH: A Benchmarking Toolkit for Human Genome Variant Calling.Talwalkar, A., Liptrap J., Newcomb J., Hartl C., Terhorst J., Curtis K., Bresler M., Song YS, Jordan MI, and Patterson D. Bioinformatics (Oxford, England), 2014/06/03, (2014) Read More / View Supplemental Materials
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Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia.Rajasagi, M., Shukla SA, Fritsch EF, Keskin DB, Deluca D., Carmona E., Zhang W., Sougnez C., Cibulskis K., Sidney J., Stevenson K., Ritz J., Neuberg D., Brusic V., Gabriel S., Lander E. S., Getz G., Hacohen N., and Wu CJ Blood, 2014/06/02, (2014) Read More / View Supplemental Materials
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Genome-scale neurogenetics: methodology and meaning.McCarroll, SA, Feng G., and Hyman SE Nature neuroscience, 2014/06/01, Volume 17, Issue 6, p.756-63, (2014) Read More / View Supplemental Materials
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Glycogen synthase kinase-3β inhibition ameliorates cardiac parasympathetic dysfunction in type 1 diabetic akita mice.Zhang, Y., Welzig CM, Picard KL, Du C., Wang B., Pan JQ, Kyriakis JM, Aronovitz MJ, Claycomb WC, Blanton RM, Park HJ, and Galper JB Diabetes, 2014/06/01, Volume 63, Issue 6, p.2097-113, (2014) Read More / View Supplemental Materials
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HLA-Binding Properties of Tumor Neoepitopes in Humans.Fritsch, EF, Rajasagi M., Ott PA, Brusic V., Hacohen N., and Wu CJ Cancer immunology research, 2014/06/01, Volume 2, Issue 6, p.522-9, (2014) Read More / View Supplemental Materials
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Integrated Pathway-Based Approach Identifies Association between Genomic Regions at CTCF and CACNB2 and Schizophrenia.Juraeva, D., Haenisch B., Zapatka M., Frank J., GROUP Investigators, group PSYCH-GEMS SCZ working, Witt SH, Mühleisen TW, Treutlein J., Strohmaier J., Meier S., Degenhardt F., Giegling I., Ripke S., Leber M., Lange C., Schulze TG, Mössner R., Nenadic I., Sauer H., et al. PLoS genetics, 2014/06/01, Volume 10, Issue 6, p.e1004345, (2014) Read More / View Supplemental Materials
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Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells.Hu, X., Im HK, Raj T., Brennan PJ, Trynka G., Teslovich N., Slowikowski K., Chen WM, Onengut S., Baecher-Allan C., De Jager PL, Rich SS, Stranger BE, Brenner MB, and Raychaudhuri S. PLoS genetics, 2014/06/01, Volume 10, Issue 6, p.e1004404, (2014) Read More / View Supplemental Materials
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Ubiquitin-Mediated Response to Microsporidia and Virus Infection in C. elegans.Bakowski, MA, Desjardins CA, Smelkinson MG, Dunbar TA, Lopez-Moyado IF, Rifkin SA, Cuomo CA, and Troemel ER PLoS pathogens, 2014/06/01, Volume 10, Issue 6, p.e1004200, (2014) Read More / View Supplemental Materials
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Vaccines and Melanoma.Ott, PA, Fritsch EF, Wu CJ, and Dranoff G. Hematology/oncology clinics of North America, 2014/06/01, Volume 28, Issue 3, p.559-569, (2014) Read More / View Supplemental Materials
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Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine.Van Allen, EM, Wagle N., Stojanov P., Perrin DL, Cibulskis K., Marlow S., Jane-Valbuena J., Friedrich DC, Kryukov G., Carter SL, McKenna A., Sivachenko A., Rosenberg M., Kiezun A., Voet D., Lawrence M., Lichtenstein LT, Gentry JG, Huang FW, Fostel J., et al. Nature medicine, 2014/06/01, Volume 20, Issue 6, p.682-8, (2014) Read More / View Supplemental Materials
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Whole-genome analyses of whole-brain data: working within an expanded search space.Medland, SE, Jahanshad N., Neale BM, and Thompson PM Nature neuroscience, 2014/06/01, Volume 17, Issue 6, p.791-800, (2014) Read More / View Supplemental Materials
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Protein-protein interactions and genetic diseases: The Interactome.Lage, K. Biochimica et biophysica acta, 2014/05/31, (2014) Read More / View Supplemental Materials
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The dog as a genetic model for immunoglobulin A (IgA) deficiency: Identification of several breeds with low serum IgA concentrations.Olsson, M., Frankowiack M., Tengvall K., Roosje P., Fall T., Ivansson E., Bergvall K., Hansson-Hamlin H., Sundberg K., Hedhammar A., Lindblad-Toh K., and Hammarström L. Veterinary immunology and immunopathology, 2014/05/27, (2014) Read More / View Supplemental Materials
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Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression.Lee, Y., Dominy JE, Choi YJ, Jurczak M., Tolliday N., Camporez JP, Chim H., Lim JH, Ruan HB, Yang X., Vazquez F., Sicinski P., Shulman GI, and Puigserver P. Nature, 2014/05/25, (2014) Read More / View Supplemental Materials
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Genome Sequence of the Pathogenic Fungus Sporothrix schenckii (ATCC 58251).Cuomo, CA, Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A., Goldberg J., Young S., Zeng Q., and Birren BW Genome announcements, 2014/05/22, Volume 2, Issue 3, (2014) Read More / View Supplemental Materials
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FGFR3 expression in primary and metastatic urothelial carcinoma of the bladder.Guancial, EA, Werner L., Bellmunt J., Bamias A., Choueiri TK, Ross R., Schutz FA, Park RS, O'Brien RJ, Hirsch MS, Barletta JA, Berman DM, Lis R., Loda M., Stack EC, Garraway LA, Riester M., Michor F., Kantoff PW, and Rosenberg JE Cancer medicine, 2014/05/21, (2014) Read More / View Supplemental Materials
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Identification of Inhibitors of PvdQ, an Enzyme Involved in the Synthesis of the Siderophore Pyoverdine.Wurst, JM, Drake EJ, Theriault JR, Jewett IT, VerPlank L., Perez JR, Dandapani S., Palmer M., Moskowitz SM, Schreiber SL, Munoz B., and Gulick AM ACS chemical biology, 2014/05/21, (2014) Read More / View Supplemental Materials
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PP2A-Mediated Regulation of Ras Signaling in G2 Is Essential for Stable Quiescence and Normal G1 Length.Naetar, N., Soundarapandian V., Litovchick L., Goguen KL, Sablina AA, Bowman-Colin C., Sicinski P., Hahn WC, DeCaprio JA, and Livingston DM Molecular cell, 2014/05/21, (2014) Read More / View Supplemental Materials
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Clawing through evolution: toxin diversification and convergence in the ancient lineage Chilopoda (Centipedes).Undheim, EA, Jones A., Clauser KR, Holland JW, Pineda SS, King GF, and Fry BG Molecular biology and evolution, 2014/05/20, (2014) Read More / View Supplemental Materials
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Effect of Genetic Variants Associated With Plasma Homocysteine Levels on Stroke Risk.Cotlarciuc, I., Malik R., Holliday EG, Ahmadi KR, Paré G., Psaty BM, Fornage M., Hasan N., Rinne PE, Ikram MA, Markus HS, Rosand J., Mitchell BD, Kittner SJ, Meschia JF, van Meurs JB, Uitterlinden AG, Worrall BB, Dichgans M., Sharma P., et al. Stroke; a journal of cerebral circulation, 2014/05/20, (2014) Read More / View Supplemental Materials
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A genetic association study of D-dimer levels with 50K SNPs from a candidate gene chip in four ethnic groups.Weng, LC, Tang W., Rich SS, Smith NL, Redline S., O'Donnell CJ, Basu S., Reiner AP, Delaney JA, Tracy RP, Palmer CD, Young T., Yang Q., Folsom AR, and Cushman M. Thrombosis research, 2014/05/20, (2014) Read More / View Supplemental Materials
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Whole -exome sequencing identifies rare, functional CFH variants in families with macular degeneration.Yu, Y., Triebwasser MP, Wong EK, Schramm EC, Thomas B., Reynolds R., Mardis E., Atkinson JP, Daly M., Raychaudhuri S., Kavanagh D., and Seddon JM Human molecular genetics, 2014/05/20, (2014) Read More / View Supplemental Materials
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Dectin-1 dependent LC3 recruitment to phagosomes enhances fungicidal activity in macrophages.Tam, JM, Mansour MK, Khan NS, Seward M., Puranam S., Tanne A., Sokolovska A., Becker CE, Acharya M., Baird MA, Choi AM, Davidson MW, Segal BH, Lacy-Hulbert A., Stuart LM, Xavier RJ, and Vyas JM The Journal of infectious diseases, 2014/05/19, (2014) Read More / View Supplemental Materials
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Hierarchical expression of genes controlled by the Bacillus subtilis global regulatory protein CodY.Brinsmade, SR, Alexander EL, Livny J., Stettner AI, Segrè D., Rhee KY, and Sonenshein AL Proceedings of the National Academy of Sciences of the United States of America, 2014/05/19, (2014) Read More / View Supplemental Materials
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Relating the metatranscriptome and metagenome of the human gut.Franzosa, EA, Morgan XC, Segata N., Waldron L., Reyes J., Earl AM, Giannoukos G., Boylan MR, Ciulla D., Gevers D., Izard J., Garrett WS, Chan AT, and Huttenhower C. Proceedings of the National Academy of Sciences of the United States of America, 2014/05/19, (2014) Read More / View Supplemental Materials
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Epigenomics of Alzheimer's disease.Bennett, DA, Yu L., Yang J., Srivastava GP, Aubin C., and De Jager PL Translational research : the journal of laboratory and clinical medicine, 2014/05/16, (2014) Read More / View Supplemental Materials
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Genome Sequence of Serratia plymuthica V4.Cleto, S., Van der Auwera G., Almeida C., Vieira MJ, Vlamakis H., and Kolter R. Genome announcements, 2014/05/15, Volume 2, Issue 3, (2014) Read More / View Supplemental Materials
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Global microRNA depletion suppresses tumor angiogenesis.Chen, S., Xue Y., Wu X., Le C., Bhutkar A., Bell EL, Zhang F., Langer R., and Sharp PA Genes & development, 2014/05/15, Volume 28, Issue 10, p.1054-67, (2014) Read More / View Supplemental Materials
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A Notch for noncoding RNA in melanoma.Garraway, LA The New England journal of medicine, 2014/05/15, Volume 370, Issue 20, p.1950-1, (2014) Read More / View Supplemental Materials
Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of β-catenin.Durak, O., de Anda FC, Singh KK, Leussis MP, Petryshen TL, Sklar P., and Tsai LH Molecular psychiatry, 2014/05/13, (2014) Read More / View Supplemental Materials
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Interactions between chromosomal and nonchromosomal elements reveal missing heritability.Edwards, MD, Symbor-Nagrabska A., Dollard L., Gifford DK, and Fink GR Proceedings of the National Academy of Sciences of the United States of America, 2014/05/13, (2014) Read More / View Supplemental Materials
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Oribacterium parvum , sp. nov. and Oribacterium asaccharolyticum sp. nov. obligately anaerobic bacteria from the human oral cavity.Sizova, MV, Muller PA Jr, Stancyk DA, Panikov NS, Mandalakis M., Hazen A., Hohmann T., Doerfert SN, Fowle W., Earl AM, Nelson KE, and Epstein SS International journal of systematic and evolutionary microbiology, 2014/05/13, (2014) Read More / View Supplemental Materials
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Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing.Helman, E., Lawrence ML, Stewart C., Sougnez C., Getz G., and Meyerson M. Genome research, 2014/05/13, (2014) Read More / View Supplemental Materials
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Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense.Lassen, KG, Kuballa P., Conway KL, Patel KK, Becker CE, Peloquin JM, Villablanca EJ, Norman JM, Liu TC, Heath RJ, Becker ML, Fagbami L., Horn H., Mercer J., Yilmaz OH, Jaffe JD, Shamji AF, Bhan AK, Carr SA, Daly M. J., et al. Proceedings of the National Academy of Sciences of the United States of America, 2014/05/12, (2014) Read More / View Supplemental Materials
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Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression.Xu, C., Fillmore CM, Koyama S., Wu H., Zhao Y., Chen Z., Herter-Sprie GS, Akbay EA, Tchaicha JH, Altabef A., Reibel JB, Walton Z., Ji H., Watanabe H., Jänne PA, Castrillon DH, Rustgi AK, Bass AJ, Freeman GJ, Padera RF, et al. Cancer cell, 2014/05/12, Volume 25, Issue 5, p.590-604, (2014) Read More / View Supplemental Materials
Abstract
A framework for installable external tools in Skyline.Broudy, D., Killeen T., Choi M., Shulman N., Mani D. R., Abbatiello SE, Mani D., Ahmad R., Sahu AK, Schilling B., Tamura K., Boss Y., Sharma V., Gibson BW, Carr SA, Vitek O., Maccoss MJ, and Maclean B. Bioinformatics (Oxford, England), 2014/05/09, (2014) Read More / View Supplemental Materials
Abstract
The uniporter: From newly identified parts to function.Kamer, KJ, Sancak Y., and Mootha VK Biochemical and biophysical research communications, 2014/05/09, (2014) Read More / View Supplemental Materials
Life Extension Factor Klotho Enhances Cognition.Dubal, DB, Yokoyama JS, Zhu L., Broestl L., Worden K., Wang D., Sturm VE, Kim D., Klein E., Yu GQ, Ho K., Eilertson KE, Yu L., Kuro-O M., De Jager PL, Coppola G., Small GW, Bennett DA, Kramer JH, Abraham CR, et al. Cell reports, 2014/05/07, (2014) Read More / View Supplemental Materials
Abstract
Mycobacterial esx-3 requires multiple components for iron acquisition.Siegrist, MS, Steigedal M., Ahmad R., Mehra A., Dragset MS, Schuster BM, Philips JA, Carr SA, and Rubin EJ mBio, 2014/05/06, Volume 5, Issue 3, (2014) Read More / View Supplemental Materials
Abstract
Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins.Gong, Y., Zack TI, Morris LG, Lin K., Hukkelhoven E., Raheja R., Tan IL, Turcan S., Veeriah S., Meng S., Viale A., Schumacher SE, Palmedo P., Beroukhim R., and Chan TA Nature genetics, 2014/05/04, (2014) Read More / View Supplemental Materials
Abstract
Whole exome sequencing identifies three recessive FIG4 mutations in an apparently dominant pedigree with Charcot-Marie-Tooth disease.Menezes, MP, Waddell L., Lenk GM, Kaur S., Macarthur DG, Meisler MH, and Clarke NF Neuromuscular disorders : NMD, 2014/05/04, (2014) Read More / View Supplemental Materials
Abstract
A Genome-Wide Association Study Identifies Variants in Casein Kinase II (CSNK2A2) to be Associated with Leukocyte Telomere Length in a Punjabi Sikh Diabetic Cohort.Saxena, R., Bjonnes A., Prescott J., Dib P., Natt P., Lane J., Lerner M., Cooper JA, Ye Y., Li KW, Maubaret CG, Codd V., Brackett D., Mirabello L., Kraft P., Dinney CP, Stowell D., Peyton M., Ralhan S., Wander GS, et al. Circulation. Cardiovascular genetics, 2014/05/03, (2014) Read More / View Supplemental Materials
Abstract
Systems genetics: From GWAS to disease pathways.van der Sijde, MR, Ng A., and Fu J. Biochimica et biophysica acta, 2014/05/02, (2014) Read More / View Supplemental Materials
Abstract
Allelic Expression of Deleterious Protein-Coding Variants across Human Tissues.Kukurba, KR, Zhang R., Li X., Smith KS, Knowles DA, How Tan M., Piskol R., Lek M., Snyder M., Macarthur DG, Li JB, and Montgomery SB PLoS genetics, 2014/05/01, Volume 10, Issue 5, p.e1004304, (2014) Read More / View Supplemental Materials
Abstract
Biallelic Variants in TTLL5, Encoding a Tubulin Glutamylase, Cause Retinal Dystrophy.Sergouniotis, PI, Chakarova C., Murphy C., Becker M., Lenassi E., Arno G., Lek M., Macarthur DG, UCL-Exomes Consortium, Bhattacharya SS, Moore AT, Holder GE, Robson AG, Wolfrum U., Webster AR, and Plagnol V. American journal of human genetics, 2014/05/01, Volume 94, Issue 5, p.760-9, (2014) Read More / View Supplemental Materials
Abstract
Breaking Down RET Breakpoints in Lung Adenocarcinoma.Watanabe, H., Brooks AN, and Meyerson M. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2014/05/01, Volume 9, Issue 5, p.590-2, (2014) Read More / View Supplemental Materials
Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal.Sun, D., Luo M., Jeong M., Rodriguez B., Xia Z., Hannah R., Wang H., Le T., Faull KF, Chen R., Gu H., Bock C., Meissner A., Göttgens B., Darlington GJ, Li W., and Goodell MA Cell stem cell, 2014/05/01, Volume 14, Issue 5, p.673-88, (2014) Read More / View Supplemental Materials
Abstract
Genomic insights into tuberculosis.Galagan, JE Nature reviews. Genetics, 2014/05/01, Volume 15, Issue 5, p.307-20, (2014) Read More / View Supplemental Materials
Abstract
Quality control and conduct of genome-wide association meta-analyses.Winkler, TW, Day FR, Croteau-Chonka DC, Wood AR, Locke AE, Mägi R., Ferreira T., Fall T., Graff M., Justice AE, Luan J., Gustafsson S., Randall JC, Vedantam S., Workalemahu T., Kilpeläinen TO, Scherag A., Esko T., Kutalik Z., Heid IM, et al. Nature protocols, 2014/05/01, Volume 9, Issue 5, p.1192-212, (2014) Read More / View Supplemental Materials
Abstract
Regulatory T cells in autoimmune neuroinflammation.Kleinewietfeld, M., and Hafler DA Immunological reviews, 2014/05/01, Volume 259, Issue 1, p.231-44, (2014) Read More / View Supplemental Materials
Abstract
Ribosomal Protein Mutations Induce Autophagy through S6 Kinase Inhibition of the Insulin Pathway.Heijnen, HF, van Wijk R., Pereboom TC, Goos YJ, Seinen CW, van Oirschot BA, van Dooren R., Gastou M., Giles RH, van Solinge W., Kuijpers TW, Gazda HT, Bierings MB, Da Costa L., and Macinnes AW PLoS genetics, 2014/05/01, Volume 10, Issue 5, p.e1004371, (2014) Read More / View Supplemental Materials
Abstract
Selectivity in Genetic Association with Sub-classified Migraine in Women.Chasman, DI, Anttila V., Buring JE, Ridker PM, Schürks M., Kurth T., and International Headache Genetics Consortium PLoS genetics, 2014/05/01, Volume 10, Issue 5, p.e1004366, (2014) Read More / View Supplemental Materials
Abstract
Simulation of finnish population history, guided by empirical genetic data, to assess power of rare-variant tests in Finland.Wang, SR, Agarwala V., Flannick J., Chiang CW, Altshuler D., GoT2D Consortium, and Hirschhorn JN American journal of human genetics, 2014/05/01, Volume 94, Issue 5, p.710-20, (2014) Read More / View Supplemental Materials
Abstract
Towards Engineered Processes for Sequencing-Based Analysis of Single Circulating Tumor Cells.Adalsteinsson, VA, and Love JC Current opinion in chemical engineering, 2014/05/01, Volume 4, p.97-104, (2014) Read More / View Supplemental Materials
Abstract
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer.Lohr, JG, Adalsteinsson VA, Cibulskis K., Choudhury AD, Rosenberg M., Cruz-Gordillo P., Francis JM, Zhang CZ, Shalek AK, Satija R., Trombetta JJ, Lu D., Tallapragada N., Tahirova N., Kim S., Blumenstiel B., Sougnez C., Lowe A., Wong B., Auclair D., et al. Nature biotechnology, 2014/05/01, Volume 32, Issue 5, p.479-84, (2014) Read More / View Supplemental Materials
Abstract
Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation.Avanesov, AS, Ma S., Pierce KA, Yim SH, Lee BC, Clish CB, and Gladyshev VN eLife, 2014/04/29, Volume 3, p.e02077, (2014) Read More / View Supplemental Materials
Abstract
'Lnc'-ing enhancers to MYC regulation.Younger, ST, and Rinn JL Cell research, 2014/04/29, (2014) Read More / View Supplemental Materials
Abstract
Natural selection and infectious disease in human populations.Karlsson, EK, Kwiatkowski DP, and Sabeti PC Nature reviews. Genetics, 2014/04/29, (2014) Read More / View Supplemental Materials
Abstract
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