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2008
ALLPATHS: de novo assembly of whole-genome shotgun microreads.Butler, J., Maccallum I., Kleber M., Shlyakhter IA, Belmonte MK, Lander E. S., Nusbaum C., and Jaffe DB Genome research, 2008/05/01, Volume 18, Issue 5, p.810-20, (2008) Read More / View Supplemental Materials
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Can one learn history from the allelic spectrum?Myers, S., Fefferman C., and Patterson N. Theoretical population biology, 2008/05/01, Volume 73, Issue 3, p.342-8, (2008) Read More / View Supplemental Materials
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Development of a fluorescence polarization based assay for histone deacetylase ligand discovery.Mazitschek, R., Patel V., Wirth DF, and Clardy J. Bioorganic & medicinal chemistry letters, 2008/05/01, Volume 18, Issue 9, p.2809-12, (2008) Read More / View Supplemental Materials
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Identification of ten loci associated with height highlights new biological pathways in human growth.Lettre, G., Jackson AU, Gieger C., Schumacher FR, Berndt SI, Sanna S., Eyheramendy S., Voight BF, Butler JL, Guiducci C., Illig T., Hackett R., Heid IM, Jacobs KB, Lyssenko V., Uda M., Diabetes Genetics Initiative, FUSION, KORA, Prostate, Lung Colorectal and Ovarian Cancer Screening Trial, et al. Nature genetics, 2008/05/01, Volume 40, Issue 5, p.584-91, (2008) Read More / View Supplemental Materials
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Mapping and sequencing of structural variation from eight human genomes.Kidd, JM, Cooper GM, Donahue WF, Hayden HS, Sampas N., Graves T., Hansen N., Teague B., Alkan C., Antonacci F., Haugen E., Zerr T., Yamada NA, Tsang P., Newman TL, Tüzün E., Cheng Z., Ebling HM, Tusneem N., David R., et al. Nature, 2008/05/01, Volume 453, Issue 7191, p.56-64, (2008) Read More / View Supplemental Materials
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Quality scores and SNP detection in sequencing-by-synthesis systems.Brockman, W., Alvarez P., Young S., Garber M., Giannoukos G., Lee WL, Russ C., Lander E. S., Nusbaum C., and Jaffe DB Genome research, 2008/05/01, Volume 18, Issue 5, p.763-70, (2008) Read More / View Supplemental Materials
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Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): I. CIP Treatment of Samples and Tailing Reaction with Terminal Transferase.Liu, CL, Bernstein BE, and Schreiber SL CSH protocols, 2008/05/01, Volume 2008, p.pdb.prot5002, (2008) Read More / View Supplemental Materials
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Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): II. Second-Strand Synthesis and In Vitro Transcription.Liu, CL, Bernstein BE, and Schreiber SL CSH protocols, 2008/05/01, Volume 2008, p.pdb.prot5003, (2008) Read More / View Supplemental Materials
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Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): III. Sample Purification.Liu, CL, Bernstein BE, and Schreiber SL CSH protocols, 2008/05/01, Volume 2008, p.pdb.prot5004, (2008) Read More / View Supplemental Materials
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Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): Overview.Liu, CL, Bernstein BE, and Schreiber SL CSH protocols, 2008/05/01, Volume 2008, p.pdb.top42, (2008) Read More / View Supplemental Materials
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Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastasesXu, Lei, Shen Steven S., Hoshida Yujin, Subramanian Aravind, Ross Ken, Brunet Jean-Philippe, Wagner Stephan N., Ramaswamy Sridhar, Mesirov Jill P., and Hynes Richard O. Molecular Cancer Research: MCR, 2008/05//, Volume 6, Issue 5, p.760 - 9, (2008) Read More / View Supplemental Materials
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Performance and scalability of discriminative metrics for comparative gene identification in 12 Drosophila genomes.Lin, MF, Deoras AN, Rasmussen MD, and Kellis M. PLoS computational biology, 2008/04/18, Volume 4, Issue 4, p.e1000067, (2008) Read More / View Supplemental Materials
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Zinc-catalyzed silylation of terminal alkynes.Rahaim RJ, Jr, and Shaw JT The Journal of organic chemistry, 2008/04/04, Volume 73, Issue 7, p.2912-5, (2008) Read More / View Supplemental Materials
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Small-molecule fluorophores to detect cell-state switching in the context of high-throughput screening.Wagner, BK, Carrinski HA, Ahn YH, Kim YK, Gilbert TJ, Fomina DA, Schreiber SL, Chang YT, and Clemons PA Journal of the American Chemical Society, 2008/04/02, Volume 130, Issue 13, p.4208-9, (2008) Read More / View Supplemental Materials
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Using CellProfiler for automatic identification and measurement of biological objects in images.Vokes, MS, and Carpenter AE Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.], 2008/04/01, Volume Chapter 14, p.Unit 14.17, (2008) Read More / View Supplemental Materials
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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.Christofk, HR, Vander Heiden MG, Harris MH, Ramanathan A., Gerszten RE, Wei R., Fleming MD, Schreiber SL, and Cantley LC Nature, 2008/03/13, Volume 452, Issue 7184, p.230-3, (2008) Read More / View Supplemental Materials
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Large-scale chemical dissection of mitochondrial function.Wagner, BK, Kitami T., Gilbert TJ, Peck D., Ramanathan A., Schreiber SL, Golub T. R., and Mootha VK Nature biotechnology, 2008/03/01, Volume 26, Issue 3, p.343-51, (2008) Read More / View Supplemental Materials
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Small-molecule reagents for cellular pull-down experiments.Wang, X., Imber BS, and Schreiber SL Bioconjugate chemistry, 2008/03/01, Volume 19, Issue 3, p.585-7, (2008) Read More / View Supplemental Materials
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SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphomaChen, Linfeng, Monti Stefano, Juszczynski Przemyslaw, Daley John, Chen Wen, Witzig Thomas E., Habermann Thomas M., Kutok Jeffery L., and Shipp Margaret A. Blood, 2008/02/15/, Volume 111, Issue 4, p.2230 - 7, (2008) Read More / View Supplemental Materials
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Complex selection on intron size in Cryptococcus neoformans.Hughes, SS, Buckley CO, and Neafsey DE Molecular biology and evolution, 2008/02/01, Volume 25, Issue 2, p.247-53, (2008) Read More / View Supplemental Materials
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An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndrome.Ebert, BL, Galili N., Tamayo P., Bosco J., Mak R., Pretz J., Tanguturi S., Ladd-Acosta C., Stone R., Golub T. R., and Raza A. PLoS medicine, 2008/02/01, Volume 5, Issue 2, p.e35, (2008) Read More / View Supplemental Materials
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Modeling genomic diversity and tumor dependency in malignant melanoma.Lin, WM, Baker AC, Beroukhim R., Winckler W., Feng W., Marmion JM, Laine E., Greulich H., Tseng H., Gates C., Hodi FS, Dranoff G., Sellers WR, Thomas RK, Meyerson M., Golub T. R., Dummer R., Herlyn M., Getz G., and Garraway LA Cancer research, 2008/02/01, Volume 68, Issue 3, p.664-73, (2008) Read More / View Supplemental Materials
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An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndromeEbert, Benjamin L., Galili Naomi, Tamayo Pablo, Bosco Jocelyn, Mak Raymond, Pretz Jennifer, Tanguturi Shyam, Ladd-Acosta Christine, Stone Richard, Golub Todd R., and Raza Azra PLoS Medicine, 2008/02//, Volume 5, Issue 2, p.e35 - e35, (2008) Read More / View Supplemental Materials
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An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndromeEbert, Benjamin L., Galili Naomi, Tamayo Pablo, Bosco Jocelyn, Mak Raymond, Pretz Jennifer, Tanguturi Shyam, Ladd-Acosta Christine, Stone Richard, Golub Todd R., and Raza Azra PLoS Medicine, 2008/02//, Volume 5, Issue 2, p.e35 - e35, (2008) Read More / View Supplemental Materials
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Cancer: hay in a haystackShannon, Kevin M., and Le Beau Michelle M. Nature, 2008/01/17/, Volume 451, Issue 7176, p.252 - 3, (2008) Read More / View Supplemental Materials
Identification of RPS14 as a 5q- syndrome gene by RNA interference screenEbert, Benjamin L., Pretz Jennifer, Bosco Jocelyn, Chang Cindy Y., Tamayo Pablo, Galili Naomi, Raza Azra, Root David E., Attar Eyal, Ellis Steven R., and Golub Todd R. Nature, 2008/01/17/, Volume 451, Issue 7176, p.335 - 9, (2008) Read More / View Supplemental Materials
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Identification of RPS14 as a 5q- syndrome gene by RNA interference screen.Ebert, BL, Pretz J., Bosco J., Chang CY, Tamayo P., Galili N., Raza A., Root DE, Attar E., Ellis SR, and Golub T. R. Nature, 2008/01/17, Volume 451, Issue 7176, p.335-9, (2008) Read More / View Supplemental Materials
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Integrative analysis reveals 53BP1 copy loss and decreased expression in a subset of human diffuse large B-cell lymphomasTakeyama, K., Monti S., Manis J. P., Cin Dal P., Getz G., Beroukhim R., Dutt S., Aster J. C., Alt F. W., Golub T. R., and Shipp M. A. Oncogene, 2008/01/10/, Volume 27, Issue 3, p.318 - 22, (2008) Read More / View Supplemental Materials
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Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity.Nieland, TJ, Shaw JT, Jaipuri FA, Duffner JL, Koehler AN, Banakos S., Zannis VI, Kirchhausen T., and Krieger M. Biochemistry, 2008/01/08, Volume 47, Issue 1, p.460-72, (2008) Read More / View Supplemental Materials
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Analysis of alternative splicing in plants with bioinformatics tools.Haas, BJ Current topics in microbiology and immunology, 2008/01/01, Volume 326, p.17-37, (2008) Read More / View Supplemental Materials
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ChemBank: a small-molecule screening and cheminformatics resource database.Seiler, KP, George GA, Happ MP, Bodycombe NE, Carrinski HA, Norton S., Brudz S., Sullivan JP, Muhlich J., Serrano M., Ferraiolo P., Tolliday NJ, Schreiber SL, and Clemons PA Nucleic acids research, 2008/01/01, Volume 36, Issue Database issue, p.D351-9, (2008) Read More / View Supplemental Materials
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Conservation of the chitin utilization pathway in the Vibrionaceae.Hunt, DE, Gevers D., Vahora NM, and Polz MF Applied and environmental microbiology, 2008/01/01, Volume 74, Issue 1, p.44-51, (2008) Read More / View Supplemental Materials
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Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity.Shaham, O., Wei R., Wang TJ, Ricciardi C., Lewis GD, Vasan RS, Carr SA, Thadhani R., Gerszten RE, and Mootha VK Molecular systems biology, 2008/01/01, Volume 4, p.214, (2008) Read More / View Supplemental Materials
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Probing the cancer genome.Greulich, H. Genome biology, 2008/01/01, Volume 9, Issue 5, p.309, (2008) Read More / View Supplemental Materials
A single Hox locus in Drosophila produces functional microRNAs from opposite DNA strands.Stark, A., Bushati N., Jan CH, Kheradpour P., Hodges E., Brennecke J., Bartel DP, Cohen SM, and Kellis M. Genes & development, 2008/01/01, Volume 22, Issue 1, p.8-13, (2008) Read More / View Supplemental Materials
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Towards the optimal screening collection: a synthesis strategy.Nielsen, TE, and Schreiber SL Angewandte Chemie (International ed. in English), 2007/12/13, Volume 47, Issue 1, p.48-56, (2008) Read More / View Supplemental Materials
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Boosting permutation tests for marker selectionGad Getz, Joshua Gold, Stefano Monti, (2008) Read More / View Supplemental Materials
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An erythroid differentiation signature predicts response to lenalidomide in Myelodysplastic SyndromeBenjamin L. Ebert, Naomi Galili, Pablo Tamayo Jocelyn Bosco Raymond Mak Jennifer Pretz Christine Ladd-Acosta Richard Stone, and Raza Azra, Volume 5, Issue 2, p.e35, (2008) Read More / View Supplemental Materials
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Gene Expression Changes in an Animal Melanoma Model Correlate with Aggressiveness of Human Melanoma MetastasesLei Xu, Steven S. Shen, Yujin Hoshida Aravind Subramanian Ken Ross Jean-Philippe Brunet Stephan Wagner Sridhar Ramaswamy N., and Hynes Richard O., Volume 6, Issue May 1, p.760-769, (2008) Read More / View Supplemental Materials
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High-resolution mapping of copy-number alterations with massively parallel sequencingDerek Y. Chiang, Gad Getz, David Jaffe Xiaojun Zhao Scott Carter Carsten Russ Chad Nusbaum Matthew Meyerson Eric B. L., (2008) Read More / View Supplemental Materials
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2007
Assessing the significance of chromosomal aberrations in cancer: methodology and application to gliomaBeroukhim, Rameen, Getz Gad, Nghiemphu Leia, Barretina Jordi, Hsueh Teli, Linhart David, Vivanco Igor, Lee Jeffrey C., Huang Julie H., Alexander Sethu, Du Jinyan, Kau Tweeny, Thomas Roman K., Shah Kinjal, Soto Horacio, Perner Sven, Prensner John, and Debiasi Ralp Proceedings of the National Academy of Sciences of the United States of America, 2007/12/11/, Volume 104, Issue 50, p.20007 - 12, (2007) Read More / View Supplemental Materials
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Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma.Beroukhim, R., Getz G., Nghiemphu L., Barretina J., Hsueh T., Linhart D., Vivanco I., Lee JC, Huang JH, Alexander S., Du J., Kau T., Thomas RK, Shah K., Soto H., Perner S., Prensner J., Debiasi RM, Demichelis F., Hatton C., et al. Proceedings of the National Academy of Sciences of the United States of America, 2007/12/11, Volume 104, Issue 50, p.20007-12, (2007) Read More / View Supplemental Materials
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MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia.Mi, S., Lu J., Sun M., Li Z., Zhang H., Neilly MB, Wang Y., Qian Z., Jin J., Zhang Y., Bohlander SK, Le Beau MM, Larson RA, Golub T. R., Rowley JD, and Chen J. Proceedings of the National Academy of Sciences of the United States of America, 2007/12/11, Volume 104, Issue 50, p.19971-6, (2007) Read More / View Supplemental Materials
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Characterizing the cancer genome in lung adenocarcinomaWeir, Barbara A., Woo Michele S., Getz Gad, Perner Sven, Ding Li, Beroukhim Rameen, Lin William M., Province Michael A., Kraja Aldi, Johnson Laura A., Shah Kinjal, Sato Mitsuo, Thomas Roman K., Barletta Justine A., Borecki Ingrid B., Broderick Stephen, and Chang Andre Nature, 2007/12/06/, Volume 450, Issue 7171, p.893 - 8, (2007) Read More / View Supplemental Materials
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Characterizing the cancer genome in lung adenocarcinoma.Weir, BA, Woo MS, Getz G., Perner S., Ding L., Beroukhim R., Lin WM, Province MA, Kraja A., Johnson LA, Shah K., Sato M., Thomas RK, Barletta JA, Borecki IB, Broderick S., Chang AC, Chiang DY, Chirieac LR, Cho J., et al. Nature, 2007/12/06, Volume 450, Issue 7171, p.893-8, (2007) Read More / View Supplemental Materials
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Distinguishing protein-coding and noncoding genes in the human genome.Clamp, M., Fry B., Kamal M., Xie X., Cuff J., Lin MF, Kellis M., Lindblad-Toh K., and Lander E. S. Proceedings of the National Academy of Sciences of the United States of America, 2007/12/04, Volume 104, Issue 49, p.19428-33, (2007) Read More / View Supplemental Materials
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28-way vertebrate alignment and conservation track in the UCSC Genome Browser.Miller, W., Rosenbloom K., Hardison RC, Hou M., Taylor J., Raney B., Burhans R., King DC, Baertsch R., Blankenberg D., Kosakovsky Pond SL, Nekrutenko A., Giardine B., Harris RS, Tyekucheva S., Diekhans M., Pringle TH, Murphy WJ, Lesk A., Weinstock GM, et al. Genome research, 2007/12/01, Volume 17, Issue 12, p.1797-808, (2007) Read More / View Supplemental Materials
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GSEA-P: a desktop application for Gene Set Enrichment Analysis.Subramanian, A., Kuehn H., Gould J., Tamayo P., and Mesirov J. P. Bioinformatics (Oxford, England), 2007/12/01, Volume 23, Issue 23, p.3251-3, (2007) Read More / View Supplemental Materials
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Identification of driver and passenger mutations of FLT3 by high-throughput DNA sequence analysis and functional assessment of candidate alleles.Fröhling, S., Scholl C., Levine RL, Loriaux M., Boggon TJ, Bernard OA, Berger R., Döhner H., Döhner K., Ebert BL, Teckie S., Golub T. R., Jiang J., Schittenhelm MM, Lee BH, Griffin JD, Stone RM, Heinrich MC, Deininger MW, Druker BJ, et al. Cancer cell, 2007/12/01, Volume 12, Issue 6, p.501-13, (2007) Read More / View Supplemental Materials
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N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli.Mukherjee, S., Robinson CA, Howe AG, Mazor T., Wood PA, Urgaonkar S., Hebert AM, Raychaudhuri D., and Shaw JT Bioorganic & medicinal chemistry letters, 2007/12/01, Volume 17, Issue 23, p.6651-5, (2007) Read More / View Supplemental Materials
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Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution.Keshishian, H., Addona T., Burgess M., Kuhn E., and Carr SA Molecular & cellular proteomics : MCP, 2007/12/01, Volume 6, Issue 12, p.2212-29, (2007) Read More / View Supplemental Materials
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Revisiting the protein-coding gene catalog of Drosophila melanogaster using 12 fly genomes.Lin, MF, Carlson JW, Crosby MA, Matthews BB, Yu C., Park S., Wan KH, Schroeder AJ, Gramates LS, St Pierre SE, Roark M., Wiley KL Jr, Kulathinal RJ, Zhang P., Myrick KV, Antone JV, Celniker SE, Gelbart WM, and Kellis M. Genome research, 2007/12/01, Volume 17, Issue 12, p.1823-36, (2007) Read More / View Supplemental Materials
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Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes.Stark, A., Kheradpour P., Parts L., Brennecke J., Hodges E., Hannon GJ, and Kellis M. Genome research, 2007/12/01, Volume 17, Issue 12, p.1865-79, (2007) Read More / View Supplemental Materials
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Two independent alleles at 6q23 associated with risk of rheumatoid arthritis.Plenge, RM, Cotsapas C., Davies L., Price AL, de Bakker PI, Maller J., Pe'er I., Burtt NP, Blumenstiel B., DeFelice M., Parkin M., Barry R., Winslow W., Healy C., Graham RR, Neale BM, Izmailova E., Roubenoff R., Parker AN, Glass R., et al. Nature genetics, 2007/12/01, Volume 39, Issue 12, p.1477-82, (2007) Read More / View Supplemental Materials
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Subclass mapping: identifying common subtypes in independent disease data sets.Hoshida, Y., Brunet JP, Tamayo P., Golub T. R., and Mesirov J. P. PloS one, 2007/11/21, Volume 2, Issue 11, p.e1195, (2007) Read More / View Supplemental Materials
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High expression of lymphocyte-associated genes in node-negative HER2+ breast cancers correlates with lower recurrence ratesAlexe, Gabriela, Dalgin Gul S., Scanfeld Daniel, Tamayo Pablo, Mesirov Jill P., DeLisi Charles, Harris Lyndsay, Barnard Nicola, Martel Maritza, Levine Arnold J., Ganesan Shridar, and Bhanot Gyan Cancer Research, 2007/11/15/, Volume 67, Issue 22, p.10669 - 76, (2007) Read More / View Supplemental Materials
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High expression of lymphocyte-associated genes in node-negative HER2+ breast cancers correlates with lower recurrence rates.Alexe, G., Dalgin GS, Scanfeld D., Tamayo P., Mesirov J. P., Delisi C., Harris L., Barnard N., Martel M., Levine AJ, Ganesan S., and Bhanot G. Cancer research, 2007/11/15, Volume 67, Issue 22, p.10669-76, (2007) Read More / View Supplemental Materials
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Altered microRNA expression in human heart disease.Ikeda, S., Kong SW, Lu J., Bisping E., Zhang H., Allen PD, Golub T. R., Pieske B., and Pu WT Physiological genomics, 2007/11/14, Volume 31, Issue 3, p.367-73, (2007) Read More / View Supplemental Materials
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Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures.Stark, A., Lin MF, Kheradpour P., Pedersen JS, Parts L., Carlson JW, Crosby MA, Rasmussen MD, Roy S., Deoras AN, Ruby JG, Brennecke J., curators Harvard FlyBase, Berkeley Drosophila Genome Project, Hodges E., Hinrichs AS, Caspi A., Paten B., Park SW, Han MV, et al. Nature, 2007/11/08, Volume 450, Issue 7167, p.219-32, (2007) Read More / View Supplemental Materials
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Evolution of genes and genomes on the Drosophila phylogeny.Drosophila 12 Genomes, Consortium, Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B., Markow TA, Kaufman TC, Kellis M., Gelbart W., Iyer VN, Pollard DA, Sackton TB, Larracuente AM, Singh ND, Abad JP, Abt DN, Adryan B., Aguade M., Akashi H., et al. Nature, 2007/11/08, Volume 450, Issue 7167, p.203-18, (2007) Read More / View Supplemental Materials
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Identification of prostate cancer modifier pathways using parental strain expression mapping.Xu, Q., Majumder PK, Ross K., Shim Y., Golub T. R., Loda M., and Sellers WR Proceedings of the National Academy of Sciences of the United States of America, 2007/11/06, Volume 104, Issue 45, p.17771-6, (2007) Read More / View Supplemental Materials
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Efficient mapping of mendelian traits in dogs through genome-wide association.Karlsson, EK, Baranowska I., Wade CM, Salmon Hillbertz NH, Zody MC, Anderson N., Biagi TM, Patterson N., Pielberg GR, Kulbokas EJ 3rd, Comstock KE, Keller ET, Mesirov J. P., von Euler H., Kämpe O., Hedhammar A., Lander E. S., Andersson G., Andersson L., and Lindblad-Toh K. Nature genetics, 2007/11/01, Volume 39, Issue 11, p.1321-8, (2007) Read More / View Supplemental Materials
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Genome-wide detection and characterization of positive selection in human populations.Sabeti, PC, Varilly P., Fry B., Lohmueller J., Hostetter E., Cotsapas C., Xie X., Byrne EH, McCarroll SA, Gaudet R., Schaffner SF, Lander E. S., International HapMap Consortium, Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, Belmont JW, et al. Nature, 2007/10/18, Volume 449, Issue 7164, p.913-8, (2007) Read More / View Supplemental Materials
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Lesional gene expression profiling in cutaneous T-cell lymphoma reveals natural clusters associated with disease outcomeShin, Jessica, Monti Stefano, Aires Daniel J., Duvic Madeleine, Golub Todd, Jones David A., and Kupper Thomas S. Blood, 2007/10/15/, Volume 110, Issue 8, p.3015 - 27, (2007) Read More / View Supplemental Materials
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Identification of novel epoxide inhibitors of hepatitis C virus replication using a high-throughput screen.Peng, LF, Kim SS, Matchacheep S., Lei X., Su S., Lin W., Runguphan W., Choe WH, Sakamoto N., Ikeda M., Kato N., Beeler AB, Porco JA Jr, Schreiber SL, and Chung RT Antimicrobial agents and chemotherapy, 2007/10/01, Volume 51, Issue 10, p.3756-9, (2007) Read More / View Supplemental Materials
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MicroRNAs and cancerCowland, Jack B., Hother Christoffer, and Gr APMIS: Acta Pathologica, Microbiologica, Et Immunologica Scandinavica, 2007/10//, Volume 115, Issue 10, p.1090 - 106, (2007) Read More / View Supplemental Materials
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Diastereoselective synthesis of gamma-lactams by a one-pot, four-component reaction.Wei, J., and Shaw JT Organic letters, 2007/09/27, Volume 9, Issue 20, p.4077-80, (2007) Read More / View Supplemental Materials
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TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.Plenge, RM, Seielstad M., Padyukov L., Lee AT, Remmers EF, Ding B., Liew A., Khalili H., Chandrasekaran A., Davies LR, Li W., Tan AK, Bonnard C., Ong RT, Thalamuthu A., Pettersson S., Liu C., Tian C., Chen WV, Carulli JP, et al. The New England journal of medicine, 2007/09/20, Volume 357, Issue 12, p.1199-209, (2007) Read More / View Supplemental Materials
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Detecting binding interactions using microarrays of natural product extracts.Schmitz, K., Haggarty SJ, McPherson OM, Clardy J., and Koehler AN Journal of the American Chemical Society, 2007/09/19, Volume 129, Issue 37, p.11346-7, (2007) Read More / View Supplemental Materials
Fluorous-based small-molecule microarrays for the discovery of histone deacetylase inhibitors.Vegas, AJ, Bradner JE, Tang W., McPherson OM, Greenberg EF, Koehler AN, and Schreiber SL Angewandte Chemie (International ed. in English), 2007/09/17, Volume 46, Issue 42, p.7960-4, (2007) Read More / View Supplemental Materials
Comment on "The consensus coding sequences of human breast and colorectal cancers".Getz, G., Höfling H., Mesirov J. P., Golub T. R., Meyerson M., Tibshirani R., and Lander E. S. Science (New York, N.Y.), 2007/09/14, Volume 317, Issue 5844, p.1500, (2007) Read More / View Supplemental Materials
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The Fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization.Cuomo, CA, Güldener U., Xu JR, Trail F., Turgeon BG, Di Pietro A., Walton JD, Ma LJ, Baker SE, Rep M., Adam G., Antoniw J., Baldwin T., Calvo S., Chang YL, DeCaprio D., Gale LR, Gnerre S., Goswami RS, Hammond-Kosack K., et al. Science (New York, N.Y.), 2007/09/07, Volume 317, Issue 5843, p.1400-2, (2007) Read More / View Supplemental Materials
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Natural history and evolutionary principles of gene duplication in fungi.Wapinski, I., Pfeffer A., Friedman N., and Regev A. Nature, 2007/09/06, Volume 449, Issue 7158, p.54-61, (2007) Read More / View Supplemental Materials
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Common genetic variation in eight genes of the GH/IGF1 axis does not contribute to adult height variation.Lettre, G., Butler JL, Ardlie KG, and Hirschhorn JN Human genetics, 2007/09/01, Volume 122, Issue 2, p.129-39, (2007) Read More / View Supplemental Materials
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Conrad: gene prediction using conditional random fields.DeCaprio, D., Vinson JP, Pearson MD, Montgomery P., Doherty M., and Galagan JE Genome research, 2007/09/01, Volume 17, Issue 9, p.1389-98, (2007) Read More / View Supplemental Materials
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New models of collaboration in genome-wide association studies: the Genetic Association Information Network.GAIN Collaborative Research, Group, Manolio TA, Rodriguez LL, Brooks L., Abecasis G., Collaborative Association Study of Psoriasis, Ballinger D., Daly M., Donnelly P., Faraone SV, International Multi-Center ADHD Genetics Project, Frazer K., Gabriel S., Gejman P., Molecular Genetics of Schizophrenia Collaboration, Guttmacher A., Harris EL, Insel T., Kelsoe JR, Bipolar Genome Study, et al. Nature genetics, 2007/09/01, Volume 39, Issue 9, p.1045-51, (2007) Read More / View Supplemental Materials
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Risk alleles for multiple sclerosis identified by a genomewide study.International Multiple Sclerosis Genetics, Consortium, Hafler DA, Compston A., Sawcer S., Lander E. S., Daly M. J., De Jager PL, de Bakker PI, Gabriel SB, Mirel DB, Ivinson AJ, Pericak-Vance MA, Gregory SG, Rioux JD, McCauley JL, Haines JL, Barcellos LF, Cree B., Oksenberg JR, and Hauser SL The New England journal of medicine, 2007/08/30, Volume 357, Issue 9, p.851-62, (2007) Read More / View Supplemental Materials
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The AP1-dependent secretion of galectin-1 by Reed Sternberg cells fosters immune privilege in classical Hodgkin lymphomaJuszczynski, Przemyslaw, Ouyang Jing, Monti Stefano, Rodig Scott J., Takeyama Kunihiko, Abramson Jeremy, Chen Wen, Kutok Jeffery L., Rabinovich Gabriel A., and Shipp Margaret A. Proceedings of the National Academy of Sciences of the United States of America, 2007/08/07/, Volume 104, Issue 32, p.13134 - 9, (2007) Read More / View Supplemental Materials
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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells.Mikkelsen, TS, Ku M., Jaffe DB, Issac B., Lieberman E., Giannoukos G., Alvarez P., Brockman W., Kim TK, Koche RP, Lee W., Mendenhall E., O'Donovan A., Presser A., Russ C., Xie X., Meissner A., Wernig M., Jaenisch R., Nusbaum C., et al. Nature, 2007/08/02, Volume 448, Issue 7153, p.553-60, (2007) Read More / View Supplemental Materials
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Analysis of breast cancer progression using principal component analysis and clustering.Alexe, G., Dalgin GS, Ganesan S., Delisi C., and Bhanot G. Journal of biosciences, 2007/08/01, Volume 32, Issue 5, p.1027-39, (2007) Read More / View Supplemental Materials
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Dual modes of natural selection on upstream open reading frames.Neafsey, DE, and Galagan JE Molecular biology and evolution, 2007/08/01, Volume 24, Issue 8, p.1744-51, (2007) Read More / View Supplemental Materials
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Evolutionarily conserved optimization of amino acid biosynthesis.Perlstein, EO, de Bivort BL, Kunes S., and Schreiber SL Journal of molecular evolution, 2007/08/01, Volume 65, Issue 2, p.186-96, (2007) Read More / View Supplemental Materials
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Image-based chemical screening.Carpenter, AE Nature chemical biology, 2007/08/01, Volume 3, Issue 8, p.461-5, (2007) Read More / View Supplemental Materials
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Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI.Nieland, TJ, Shaw JT, Jaipuri FA, Maliga Z., Duffner JL, Koehler AN, and Krieger M. Journal of lipid research, 2007/08/01, Volume 48, Issue 8, p.1832-45, (2007) Read More / View Supplemental Materials
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Positive selection for unpreferred codon usage in eukaryotic genomes.Neafsey, DE, and Galagan JE BMC evolutionary biology, 2007/07/18, Volume 7, p.119, (2007) Read More / View Supplemental Materials
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TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohortDemichelis, F., Fall K., Perner S., and Andr Oncogene, 2007/07/05/, Volume 26, Issue 31, p.4596 - 9, (2007) Read More / View Supplemental Materials
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Automatic genome-wide reconstruction of phylogenetic gene trees.Wapinski, I., Pfeffer A., Friedman N., and Regev A. Bioinformatics (Oxford, England), 2007/07/01, Volume 23, Issue 13, p.i549-58, (2007) Read More / View Supplemental Materials
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Copy-number variation and association studies of human disease.McCarroll, SA, and Altshuler DM Nature genetics, 2007/07/01, Volume 39, Issue 7 Suppl, p.S37-42, (2007) Read More / View Supplemental Materials
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Ligand design by a combinatorial approach based on modeling and experiment: application to HLA-DR4.Evensen, E., Joseph-McCarthy D., Weiss GA, Schreiber SL, and Karplus M. Journal of computer-aided molecular design, 2007/07/01, Volume 21, Issue 7, p.395-418, (2007) Read More / View Supplemental Materials
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Rethinking relationships between natural products.Schreiber, SL Nature chemical biology, 2007/07/01, Volume 3, Issue 7, p.352, (2007) Read More / View Supplemental Materials
Quantifying fitness distributions and phenotypic relationships in recombinant yeast populations.Perlstein, EO, Deeds EJ, Ashenberg O., Shakhnovich EI, and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2007/06/19, Volume 104, Issue 25, p.10553-8, (2007) Read More / View Supplemental Materials
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Integrative genomic approaches identify IKBKE as a breast cancer oncogene.Boehm, JS, Zhao JJ, Yao J., Kim SY, Firestein R., Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S., Richardson AL, Greulich H., Stewart CJ, Mulvey LA, Shen RR, Ambrogio L., Hirozane-Kishikawa T., Hill DE, Vidal M., Meyerson M., Grenier JK, et al. Cell, 2007/06/15, Volume 129, Issue 6, p.1065-79, (2007) Read More / View Supplemental Materials
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.ENCODE Project, Consortium, Birney E., Stamatoyannopoulos JA, Dutta A., Guigó R., Gingeras TR, Margulies EH, Weng Z., Snyder M., Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S., Koch CM, Asthana S., Malhotra A., Adzhubei I., Greenbaum JA, Andrews RM, et al. Nature, 2007/06/14, Volume 447, Issue 7146, p.799-816, (2007) Read More / View Supplemental Materials
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Synthesis of diverse lactam carboxamides leading to the discovery of a new transcription-factor inhibitor.Ng, PY, Tang Y., Knosp WM, Stadler HS, and Shaw JT Angewandte Chemie (International ed. in English), 2007/06/14, Volume 46, Issue 28, p.5352-5, (2007) Read More / View Supplemental Materials
Synthesis of kaempferitrin.Urgaonkar, S., and Shaw JT The Journal of organic chemistry, 2007/06/08, Volume 72, Issue 12, p.4582-5, (2007) Read More / View Supplemental Materials
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Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome.Margulies, EH, Cooper GM, Asimenos G., Thomas DJ, Dewey CN, Siepel A., Birney E., Keefe D., Schwartz AS, Hou M., Taylor J., Nikolaev S., Montoya-Burgos JI, Löytynoja A., Whelan S., Pardi F., Massingham T., Brown JB, Bickel P., Holmes I., et al. Genome research, 2007/06/01, Volume 17, Issue 6, p.760-74, (2007) Read More / View Supplemental Materials
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Genetic determinants of QT interval variation and sudden cardiac death.Newton-Cheh, C., and Shah R. Current opinion in genetics & development, 2007/06/01, Volume 17, Issue 3, p.213-21, (2007) Read More / View Supplemental Materials
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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.and of Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, Novartis Institutes BioMedical Rese, Saxena R., Voight BF, Lyssenko V., Burtt NP, de Bakker PI, Chen H., Roix JJ, Kathiresan S., Hirschhorn JN, Daly M. J., Hughes TE, Groop L., Altshuler D., Almgren P., Florez JC, Meyer J., Ardlie K., Bengtsson Boström K., Isomaa B., et al. Science (New York, N.Y.), 2007/06/01, Volume 316, Issue 5829, p.1331-6, (2007) Read More / View Supplemental Materials
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Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.Sarkar, S., Perlstein EO, Imarisio S., Pineau S., Cordenier A., Maglathlin RL, Webster JA, Lewis TA, O'Kane CJ, Schreiber SL, and Rubinsztein DC Nature chemical biology, 2007/06/01, Volume 3, Issue 6, p.331-8, (2007) Read More / View Supplemental Materials
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Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences.Mikkelsen, TS, Wakefield MJ, Aken B., Amemiya CT, Chang JL, Duke S., Garber M., Gentles AJ, Goodstadt L., Heger A., Jurka J., Kamal M., Mauceli E., Searle SM, Sharpe T., Baker ML, Batzer MA, Benos PV, Belov K., Clamp M., et al. Nature, 2007/05/10, Volume 447, Issue 7141, p.167-77, (2007) Read More / View Supplemental Materials
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