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2010
Expression analysis of loci associated with type 2 diabetes in human tissues.Cotsapas, C., Prokunina-Olsson L., Welch C., Saxena R., Weaver C., Usher N., Guiducci C., Bonakdar S., Turner N., LaCroix B., and Hall JL Diabetologia, 2010/11/01, Volume 53, Issue 11, p.2334-9, (2010) Read More / View Supplemental Materials
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LRRK2 is involved in the IFN-gamma response and host response to pathogens.Gardet, A., Benita Y., Li C., Sands BE, Ballester I., Stevens C., Korzenik JR, Rioux JD, Daly M. J., Xavier RJ, and Podolsky DK Journal of immunology (Baltimore, Md. : 1950), 2010/11/01, Volume 185, Issue 9, p.5577-85, (2010) Read More / View Supplemental Materials
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Multivariate dependence and genetic networks inference.Margolin, AA, Wang K., Califano A., and Nemenman I. IET systems biology, 2010/11/01, Volume 4, Issue 6, p.428-40, (2010) Read More / View Supplemental Materials
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Points of view: gestalt principles (part 1).Wong, B. Nature methods, 2010/11/01, Volume 7, Issue 11, p.863, (2010) Read More / View Supplemental Materials
Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma.Green, MR, Monti S., Rodig SJ, Juszczynski P., Currie T., O'Donnell E., Chapuy B., Takeyama K., Neuberg D., Golub T. R., Kutok JL, and Shipp M. A. Blood, 2010/10/28, Volume 116, Issue 17, p.3268-77, (2010) Read More / View Supplemental Materials
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SNP genotyping defines complex gene-flow boundaries among African malaria vector mosquitoes.Neafsey, DE, Lawniczak MK, Park DJ, Redmond SN, Coulibaly MB, Traoré SF, Sagnon N., Costantini C., Johnson C., Wiegand RC, Collins FH, Lander E. S., Wirth DF, Kafatos FC, Besansky NJ, Christophides GK, and Muskavitch MA Science (New York, N.Y.), 2010/10/22, Volume 330, Issue 6003, p.514-7, (2010) Read More / View Supplemental Materials
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Large non-coding RNAs: missing links in cancer?Huarte, M., and Rinn JL Human molecular genetics, 2010/10/15, Volume 19, Issue R2, p.R152-61, (2010) Read More / View Supplemental Materials
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Immunoaffinity Enrichment and Liquid Chromatography-Selected Reaction Monitoring Mass Spectrometry for Quantitation of Carbonic Anhydrase 12 in Cultured Renal Carcinoma Cells.Rafalko, A., Iliopoulos O., Fusaro VA, Hancock W., and Hincapie M. Analytical chemistry, 2010/10/11, (2010) Read More / View Supplemental Materials
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Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin.Fass, DM, Shah R., Ghosh B., Hennig K., Norton S., Zhao WN, Reis SA, Klein PS, Mazitschek R., Maglathlin RL, Lewis TA, and Haggarty SJ ACS medicinal chemistry letters, 2010/10/08, Volume 2, Issue 1, p.39-42, (2010) Read More / View Supplemental Materials
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Prepare and inspire.Lander, E. S., and Gates SJ Jr Science (New York, N.Y.), 2010/10/08, Volume 330, Issue 6001, p.151, (2010) Read More / View Supplemental Materials
Comparative epigenomic analysis of murine and human adipogenesis.Mikkelsen, TS, Xu Z., Zhang X., Wang L., Gimble JM, Lander E. S., and Rosen ED Cell, 2010/10/01, Volume 143, Issue 1, p.156-69, (2010) Read More / View Supplemental Materials
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The NIH Roadmap Epigenomics Mapping Consortium.Bernstein, BE, Stamatoyannopoulos JA, Costello JF, Ren B., Milosavljevic A., Meissner A., Kellis M., Marra MA, Beaudet AL, Ecker JR, Farnham PJ, Hirst M., Lander E. S., Mikkelsen TS, and Thomson JA Nature biotechnology, 2010/10/01, Volume 28, Issue 10, p.1045-8, (2010) Read More / View Supplemental Materials
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Quantitative comparison of genome-wide DNA methylation mapping technologies.Bock, C., Tomazou EM, Brinkman AB, Müller F., Simmer F., Gu H., Jäger N., Gnirke A., Stunnenberg HG, and Meissner A. Nature biotechnology, 2010/10/01, Volume 28, Issue 10, p.1106-14, (2010) Read More / View Supplemental Materials
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Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres.O'Sullivan, RJ, Kubicek S., Schreiber SL, and Karlseder J. Nature structural & molecular biology, 2010/10/01, Volume 17, Issue 10, p.1218-25, (2010) Read More / View Supplemental Materials
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The mitochondrial proteome and human disease.Calvo, SE, and Mootha VK Annual review of genomics and human genetics, 2010/09/22, Volume 11, p.25-44, (2010) Read More / View Supplemental Materials
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A concise silylamine approach to 2-amino-3-hydroxy-indoles with potent in vivo antimalaria activity.Urgaonkar, S., Cortese JF, Barker RH, Cromwell M., Serrano AE, Wirth DF, Clardy J., and Mazitschek R. Organic letters, 2010/09/17, Volume 12, Issue 18, p.3998-4001, (2010) Read More / View Supplemental Materials
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MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake.Perocchi, F., Gohil VM, Girgis HS, Bao XR, McCombs JE, Palmer AE, and Mootha VK Nature, 2010/09/16, Volume 467, Issue 7313, p.291-6, (2010) Read More / View Supplemental Materials
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Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function.Raychaudhuri, S., Korn JM, McCarroll SA, International Schizophrenia Consortium, Altshuler D., Sklar P., Purcell S., and Daly M. J. PLoS genetics, 2010/09/09, Volume 6, Issue 9, (2010) Read More / View Supplemental Materials
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Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2.JG, Ren, P Seth, CB Clish, P Everett, and VP Sukhatme PloS one, 2010/09/02, Volume 5, Issue 9, (2010) Read More / View Supplemental Materials
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Integrating common and rare genetic variation in diverse human populations.International HapMap 3, Consortium, Altshuler DM, Gibbs RA, Peltonen L., Altshuler DM, Gibbs RA, Peltonen L., Dermitzakis E., Schaffner SF, Yu F., Peltonen L., Dermitzakis E., Bonnen PE, Altshuler DM, Gibbs RA, de Bakker PI, Deloukas P., Gabriel SB, Gwilliam R., Hunt S., et al. Nature, 2010/09/02, Volume 467, Issue 7311, p.52-8, (2010) Read More / View Supplemental Materials
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Comprehensive comparative analysis of strand-specific RNA sequencing methods.Levin, JZ, Yassour M., Adiconis X., Nusbaum C., Thompson DA, Friedman N., Gnirke A., and Regev A. Nature methods, 2010/09/01, Volume 7, Issue 9, p.709-15, (2010) Read More / View Supplemental Materials
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The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data.McKenna, A., Hanna M., Banks E., Sivachenko A., Cibulskis K., Kernytsky A., Garimella K., Altshuler D., Gabriel S., Daly M., and DePristo MA Genome research, 2010/09/01, Volume 20, Issue 9, p.1297-303, (2010) Read More / View Supplemental Materials
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High-throughput assessment of Mammalian cell viability by determination of adenosine triphosphate levels.Tolliday, N. Current protocols in chemical biology, 2010/09/01, Volume 2, Issue 3, p.153-61, (2010) Read More / View Supplemental Materials
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A survey of sequence alignment algorithms for next-generation sequencing.Li, H., and Homer N. Briefings in bioinformatics, 2010/09/01, Volume 11, Issue 5, p.473-83, (2010) Read More / View Supplemental Materials
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Towards patient-based cancer therapeutics.Cancer Target Discovery and Development, Network, Schreiber SL, Shamji AF, Clemons PA, Hon C., Koehler AN, Munoz B., Palmer M., Stern AM, Wagner BK, Powers S., Lowe SW, Guo X., Krasnitz A., Sawey ET, Sordella R., Stein L., Trotman LC, Califano A., Dalla-Favera R., et al. Nature biotechnology, 2010/09/01, Volume 28, Issue 9, p.904-6, (2010) Read More / View Supplemental Materials
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes.Taube, JH, Herschkowitz JI, Komurov K., Zhou AY, Gupta S., Yang J., Hartwell K., Onder TT, Gupta PB, Evans KW, Hollier BG, Ram PT, Lander E. S., Rosen JM, Weinberg R. A., and Mani SA Proceedings of the National Academy of Sciences of the United States of America, 2010/08/31, Volume 107, Issue 35, p.15449-54, (2010) Read More / View Supplemental Materials
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Small-molecule inducers of insulin expression in pancreatic alpha-cells.Fomina-Yadlin, D., Kubicek S., Walpita D., Dancik V., Hecksher-Sørensen J., Bittker JA, Sharifnia T., Shamji A., Clemons PA, Wagner BK, and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2010/08/24, Volume 107, Issue 34, p.15099-104, (2010) Read More / View Supplemental Materials
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Small-Molecule Suppressors of Cytokine-Induced beta-Cell Apoptosis.Chou, DH, Bodycombe NE, Carrinski HA, Lewis TA, Clemons PA, Schreiber SL, and Wagner BK ACS chemical biology, 2010/08/20, Volume 5, Issue 8, p.729-34, (2010) Read More / View Supplemental Materials
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Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits.Segrè, AV, DIAGRAM Consortium, investigators MAGIC, Groop L., Mootha VK, Daly M. J., and Altshuler D. PLoS genetics, 2010/08/12, Volume 6, Issue 8, (2010) Read More / View Supplemental Materials
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MicroRNA miR-125a controls hematopoietic stem cell number.Guo, S., Lu J., Schlanger R., Zhang H., Wang JY, Fox MC, Purton LE, Fleming HH, Cobb B., Merkenschlager M., Golub T. R., and Scadden DT Proceedings of the National Academy of Sciences of the United States of America, 2010/08/10, Volume 107, Issue 32, p.14229-34, (2010) Read More / View Supplemental Materials
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A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response.Huarte, M., Guttman M., Feldser D., Garber M., Koziol MJ, Kenzelmann-Broz D., Khalil AM, Zuk O., Amit I., Rabani M., Attardi LD, Regev A., Lander E. S., Jacks T., and Rinn JL Cell, 2010/08/06, Volume 142, Issue 3, p.409-19, (2010) Read More / View Supplemental Materials
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Points of view: Color coding.Wong, B. Nature methods, 2010/08/01, Volume 7, Issue 8, p.573, (2010) Read More / View Supplemental Materials
Screening cellular feature measurements for image-based assay development.Logan, DJ, and Carpenter AE Journal of biomolecular screening, 2010/08/01, Volume 15, Issue 7, p.840-6, (2010) Read More / View Supplemental Materials
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Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.Barretina, J., Taylor BS, Banerji S., Ramos AH, Lagos-Quintana M., Decarolis PL, Shah K., Socci ND, Weir BA, Ho A., Chiang DY, Reva B., Mermel CH, Getz G., Antipin Y., Beroukhim R., Major JE, Hatton C., Nicoletti R., Hanna M., et al. Nature genetics, 2010/08/01, Volume 42, Issue 8, p.715-21, (2010) Read More / View Supplemental Materials
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Activation of a metabolic gene regulatory network downstream of mTOR complex 1.Düvel, K., Yecies JL, Menon S., Raman P., Lipovsky AI, Souza AL, Triantafellow E., Ma Q., Gorski R., Cleaver S., Vander Heiden MG, MacKeigan JP, Finan PM, Clish CB, Murphy LO, and Manning BD Molecular cell, 2010/07/30, Volume 39, Issue 2, p.171-83, (2010) Read More / View Supplemental Materials
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Whole proteomes as internal standards in quantitative proteomics.Ong, SE Genome medicine, 2010/07/30, Volume 2, Issue 7, p.49, (2010) Read More / View Supplemental Materials
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Emergence of the Asian 1 genotype of dengue virus serotype 2 in viet nam: in vivo fitness advantage and lineage replacement in South-East Asia.Vu, TT, Holmes EC, Duong V., Nguyen TQ, Tran TH, Quail M., Churcher C., Parkhill J., Cardosa J., Farrar J., Wills B., Lennon NJ, Birren BW, Buchy P., Henn MR, and Simmons CP PLoS neglected tropical diseases, 2010/07/20, Volume 4, Issue 7, p.e757, (2010) Read More / View Supplemental Materials
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Distinct biological network properties between the targets of natural products and disease genes.Dancík, V., Seiler KP, Young DW, Schreiber SL, and Clemons PA Journal of the American Chemical Society, 2010/07/14, Volume 132, Issue 27, p.9259-61, (2010) Read More / View Supplemental Materials
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Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease.Bradner, JE, Mak R., Tanguturi SK, Mazitschek R., Haggarty SJ, Ross K., Chang CY, Bosco J., West N., Morse E., Lin K., Shen JP, Kwiatkowski NP, Gheldof N., Dekker J., DeAngelo DJ, Carr SA, Schreiber SL, Golub T. R., and Ebert BL Proceedings of the National Academy of Sciences of the United States of America, 2010/07/13, Volume 107, Issue 28, p.12617-22, (2010) Read More / View Supplemental Materials
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Curve-based multivariate distance matrix regression analysis: application to genetic association analyses involving repeated measures.Salem, RM, O'Connor DT, and Schork NJ Physiological genomics, 2010/07/07, Volume 42, Issue 2, p.236-47, (2010) Read More / View Supplemental Materials
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The role of nucleosome positioning in the evolution of gene regulation.Tsankov, AM, Thompson DA, Socha A., Regev A., and Rando OJ PLoS biology, 2010/07/06, Volume 8, Issue 7, p.e1000414, (2010) Read More / View Supplemental Materials
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Cardiac Arrhythmia: In vivo screening in the zebrafish to overcome complexity in drug discovery.Macrae, CA Expert opinion on drug discovery, 2010/07/01, Volume 5, Issue 7, p.619-632, (2010) Read More / View Supplemental Materials
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New approaches to population stratification in genome-wide association studies.Price, AL, Zaitlen NA, Reich D., and Patterson N. Nature reviews. Genetics, 2010/07/01, Volume 11, Issue 7, p.459-63, (2010) Read More / View Supplemental Materials
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Population genomic sequencing of Coccidioides fungi reveals recent hybridization and transposon control.Neafsey, DE, Barker BM, Sharpton TJ, Stajich JE, Park DJ, Whiston E., Hung CY, McMahan C., White J., Sykes S., Heiman D., Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A., FitzGerald M., Lui A., Macdonald JP, et al. Genome research, 2010/07/01, Volume 20, Issue 7, p.938-46, (2010) Read More / View Supplemental Materials
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Targeted exon sequencing by in-solution hybrid selection.Blumenstiel, B., Cibulskis K., Fisher S., DeFelice M., Barry A., Fennell T., Abreu J., Minie B., Costello M., Young G., Maquire J., Kernytsky A., Melnikov A., Rogov P., Gnirke A., and Gabriel S. Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.], 2010/07/01, Volume Chapter 18, p.Unit 18.4, (2010) Read More / View Supplemental Materials
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TB database 2010: overview and update.Galagan, JE, Sisk P., Stolte C., Weiner B., Koehrsen M., Wymore F., Reddy TB, Zucker JD, Engels R., Gellesch M., Hubble J., Jin H., Larson L., Mao M., Nitzberg M., White J., Zachariah ZK, Sherlock G., Ball CA, and Schoolnik GK Tuberculosis (Edinburgh, Scotland), 2010/07/01, Volume 90, Issue 4, p.225-35, (2010) Read More / View Supplemental Materials
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Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.Voight, BF, Scott LJ, Steinthorsdottir V., Morris AP, Dina C., Welch RP, Zeggini E., Huth C., Aulchenko YS, Thorleifsson G., McCulloch LJ, Ferreira T., Grallert H., Amin N., Wu G., Willer CJ, Raychaudhuri S., McCarroll SA, Langenberg C., Hofmann OM, et al. Nature genetics, 2010/07/01, Volume 42, Issue 7, p.579-89, (2010) Read More / View Supplemental Materials
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RESOLVING CLUSTERED WORMS VIA PROBABILISTIC SHAPE MODELS.Wählby, C., Riklin-Raviv T., Ljosa V., Conery AL, Golland P., Ausubel FM, and Carpenter AE Proceedings / IEEE International Symposium on Biomedical Imaging: from nano to macro. IEEE International Symposium on Biomedical Imaging, 2010/06/21, Volume 2010, Issue 14-17 April 2010, p.552-555, (2010) Read More / View Supplemental Materials
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Stereochemical and skeletal diversity arising from amino propargylic alcohols.Pizzirani, D., Kaya T., Clemons PA, and Schreiber SL Organic letters, 2010/06/18, Volume 12, Issue 12, p.2822-5, (2010) Read More / View Supplemental Materials
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Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network.Aiden, AP, Rivera MN, Rheinbay E., Ku M., Coffman EJ, Truong TT, Vargas SO, Lander E. S., Haber DA, and Bernstein BE Cell stem cell, 2010/06/04, Volume 6, Issue 6, p.591-602, (2010) Read More / View Supplemental Materials
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Candidate gene association resource (CARe): design, methods, and proof of concept.Musunuru, K., Lettre G., Young T., Farlow DN, Pirruccello JP, Ejebe KG, Keating BJ, Yang Q., Chen MH, Lapchyk N., Crenshaw A., Ziaugra L., Rachupka A., Benjamin EJ, Cupples LA, Fornage M., Fox ER, Heckbert SR, Hirschhorn JN, Newton-Cheh C., et al. Circulation. Cardiovascular genetics, 2010/06/01, Volume 3, Issue 3, p.267-75, (2010) Read More / View Supplemental Materials
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Cell-based assays for high-throughput screening.An, WF, and Tolliday N. Molecular biotechnology, 2010/06/01, Volume 45, Issue 2, p.180-6, (2010) Read More / View Supplemental Materials
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Cheminformatics approaches to analyze diversity in compound screening libraries.Akella, LB, and DeCaprio D. Current opinion in chemical biology, 2010/06/01, Volume 14, Issue 3, p.325-30, (2010) Read More / View Supplemental Materials
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A complex task? Direct modulation of transcription factors with small molecules.Koehler, AN Current opinion in chemical biology, 2010/06/01, Volume 14, Issue 3, p.331-40, (2010) Read More / View Supplemental Materials
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Current strategies for diversity-oriented synthesis.Dandapani, S., and Marcaurelle LA Current opinion in chemical biology, 2010/06/01, Volume 14, Issue 3, p.362-70, (2010) Read More / View Supplemental Materials
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Metabolite profiling identifies markers of uremia.Rhee, EP, Souza A., Farrell L., Pollak MR, Lewis GD, Steele DJ, Thadhani R., Clish CB, Greka A., and Gerszten RE Journal of the American Society of Nephrology : JASN, 2010/06/01, Volume 21, Issue 6, p.1041-1051, (2010) Read More / View Supplemental Materials
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Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2.Boulbes, D., Chen CH, Shaikenov T., Agarwal NK, Peterson TR, Addona TA, Keshishian H., Carr SA, Magnuson MA, Sabatini DM, and Sarbassov dos D. Molecular cancer research : MCR, 2010/06/01, Volume 8, Issue 6, p.896-906, (2010) Read More / View Supplemental Materials
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Metabolic signatures of exercise in human plasma.Lewis, GD, Farrell L., Wood MJ, Martinovic M., Arany Z., Rowe GC, Souza A., Cheng S., McCabe EL, Yang E., Shi X., Deo R., Roth FP, Asnani A., Rhee EP, Systrom DM, Semigran MJ, Vasan RS, Carr SA, Wang TJ, et al. Science translational medicine, 2010/05/26, Volume 2, Issue 33, p.33ra37, (2010) Read More / View Supplemental Materials
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A catalog of reference genomes from the human microbiome.Human Microbiome Jumpstart Reference Strains, Consortium, Nelson KE, Weinstock GM, Highlander SK, Worley KC, Creasy HH, Wortman JR, Rusch DB, Mitreva M., Sodergren E., Chinwalla AT, Feldgarden M., Gevers D., Haas BJ, Madupu R., Ward DV, Birren BW, Gibbs RA, Methe B., Petrosino JF, et al. Science (New York, N.Y.), 2010/05/21, Volume 328, Issue 5981, p.994-9, (2010) Read More / View Supplemental Materials
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Vibrio chromosomes share common history.Kirkup BC, Jr, Chang L., Chang S., Gevers D., and Polz MF BMC microbiology, 2010/05/10, Volume 10, p.137, (2010) Read More / View Supplemental Materials
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A draft sequence of the Neandertal genome.Green, RE, Krause J., Briggs AW, Maricic T., Stenzel U., Kircher M., Patterson N., Li H., Zhai W., Fritz MH, Hansen NF, Durand EY, Malaspinas AS, Jensen JD, Marques-Bonet T., Alkan C., Prüfer K., Meyer M., Burbano HA, Good JM, et al. Science (New York, N.Y.), 2010/05/07, Volume 328, Issue 5979, p.710-22, (2010) Read More / View Supplemental Materials
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Hi-C: a method to study the three-dimensional architecture of genomes.van Berkum, NL, Lieberman-Aiden E., Williams L., Imakaev M., Gnirke A., Mirny LA, Dekker J., and Lander E. S. Journal of visualized experiments : JoVE, 2010/05/06, Issue 39, (2010) Read More / View Supplemental Materials
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Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs.Guttman, M., Garber M., Levin JZ, Donaghey J., Robinson J., Adiconis X., Fan L., Koziol MJ, Gnirke A., Nusbaum C., Rinn JL, Lander E. S., and Regev A. Nature biotechnology, 2010/05/01, Volume 28, Issue 5, p.503-10, (2010) Read More / View Supplemental Materials
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Dynamic single-cell imaging of direct reprogramming reveals an early specifying event.Smith, ZD, Nachman I., Regev A., and Meissner A. Nature biotechnology, 2010/05/01, Volume 28, Issue 5, p.521-6, (2010) Read More / View Supplemental Materials
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Genome-wide synteny through highly sensitive sequence alignment: Satsuma.Grabherr, MG, Russell P., Meyer M., Mauceli E., Alföldi J., Di Palma F., and Lindblad-Toh K. Bioinformatics (Oxford, England), 2010/05/01, Volume 26, Issue 9, p.1145-51, (2010) Read More / View Supplemental Materials
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High-quality draft genome sequences of 28 Enterococcus sp. isolates.Palmer, KL, Carniol K., Manson JM, Heiman D., Shea T., Young S., Zeng Q., Gevers D., Feldgarden M., Birren B., and Gilmore MS Journal of bacteriology, 2010/05/01, Volume 192, Issue 9, p.2469-70, (2010) Read More / View Supplemental Materials
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The connectivity map links iron regulatory protein-1-mediated inhibition of hypoxia-inducible factor-2a translation to the anti-inflammatory 15-deoxy-delta12,14-prostaglandin J2.Zimmer, M., Lamb J., Ebert BL, Lynch M., Neil C., Schmidt E., Golub T. R., and Iliopoulos O. Cancer research, 2010/04/15, Volume 70, Issue 8, p.3071-9, (2010) Read More / View Supplemental Materials
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International network of cancer genome projects.International Cancer Genome, Consortium, Hudson T. J., Anderson W., Artez A., Barker AD, Bell C., Bernabé RR, Bhan MK, Calvo F., Eerola I., Gerhard DS, Guttmacher A., Guyer M., Hemsley FM, Jennings JL, Kerr D., Klatt P., Kolar P., Kusada J., Lane DP, et al. Nature, 2010/04/15, Volume 464, Issue 7291, p.993-8, (2010) Read More / View Supplemental Materials
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Optimizing performance of glycopeptide capture for plasma proteomics.Berven, FS, Ahmad R., Clauser KR, and Carr SA Journal of proteome research, 2010/04/05, Volume 9, Issue 4, p.1706-15, (2010) Read More / View Supplemental Materials
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Counterpoint: Data first.Golub, T. Nature, 2010/04/01, Volume 464, Issue 7289, p.679, (2010) Read More / View Supplemental Materials
Endoplasmic reticulum stress and atherosclerosis.Hotamisligil, GS Nature medicine, 2010/04/01, Volume 16, Issue 4, p.396-9, (2010) Read More / View Supplemental Materials
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Genetic resistance to diet-induced obesity in chromosome substitution strains of mice.Burrage, LC, Baskin-Hill AE, Sinasac DS, Singer JB, Croniger CM, Kirby A., Kulbokas E. J., Daly M. J., Lander E. S., Broman KW, and Nadeau JH Mammalian genome : official journal of the International Mammalian Genome Society, 2010/04/01, Volume 21, Issue 3-4, p.115-29, (2010) Read More / View Supplemental Materials
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Integrative analysis of the melanoma transcriptome.Berger, MF, Levin JZ, Vijayendran K., Sivachenko A., Adiconis X., Maguire J., Johnson LA, Robinson J., Verhaak RG, Sougnez C., Onofrio RC, Ziaugra L., Cibulskis K., Laine E., Barretina J., Winckler W., Fisher DE, Getz G., Meyerson M., Jaffe DB, et al. Genome research, 2010/04/01, Volume 20, Issue 4, p.413-27, (2010) Read More / View Supplemental Materials
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Screen for RAS-Selective Lethal Compounds and VDAC LigandsBittker, JA, Weiwer M., Shimada K., Yang WS, Macpherson L., Dandapani S., Munoz B., Palmer M., Stockwell BR, and Schreiber SL, 2010/03/26, (2010) Read More / View Supplemental Materials
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Systematic discovery of regulatory motifs in Fusarium graminearum by comparing four Fusarium genomes.Kumar, L., Breakspear A., Kistler C., Ma LJ, and Xie X. BMC genomics, 2010/03/26, Volume 11, p.208, (2010) Read More / View Supplemental Materials
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Endoplasmic reticulum stress and the inflammatory basis of metabolic disease.Hotamisligil, GS Cell, 2010/03/19, Volume 140, Issue 6, p.900-17, (2010) Read More / View Supplemental Materials
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Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium.Ma, LJ, van der Does HC, Borkovich KA, Coleman JJ, Daboussi MJ, Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B., Houterman PM, Kang S., Shim WB, Woloshuk C., Xie X., Xu JR, Antoniw J., Baker SE, Bluhm BH, Breakspear A., et al. Nature, 2010/03/18, Volume 464, Issue 7287, p.367-73, (2010) Read More / View Supplemental Materials
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Molecular sampling of prostate cancer: a dilemma for predicting disease progression.Sboner, A., Demichelis F., Calza S., Pawitan Y., Setlur SR, Hoshida Y., Perner S., Adami HO, Fall K., Mucci LA, Kantoff PW, Stampfer M., Andersson SO, Varenhorst E., Johansson JE, Gerstein MB, Golub T. R., Rubin MA, and Andrén O. BMC medical genomics, 2010/03/16, Volume 3, p.8, (2010) Read More / View Supplemental Materials
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Blood pressure and human genetic variation in the general population.Arora, P., and Newton-Cheh C. Current opinion in cardiology, 2010/03/10, (2010) Read More / View Supplemental Materials
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Carbon metabolism-mediated myogenic differentiation.Bracha, AL, Ramanathan A., Huang S., Ingber DE, and Schreiber SL Nature chemical biology, 2010/03/01, Volume 6, Issue 3, p.202-204, (2010) Read More / View Supplemental Materials
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Chemical phylogenetics of histone deacetylases.Bradner, JE, West N., Grachan ML, Greenberg EF, Haggarty SJ, Warnow T., and Mazitschek R. Nature chemical biology, 2010/03/01, Volume 6, Issue 3, p.238-243, (2010) Read More / View Supplemental Materials
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Hyperlipidemia and reduced white matter hyperintensity volume in patients with ischemic stroke.Jimenez-Conde, J., Biffi A., Rahman R., Kanakis A., Butler C., Sonni S., Massasa E., Cloonan L., Gilson A., Capozzo K., Cortellini L., Ois A., Cuadrado-Godia E., Rodriguez-Campello A., Furie KL, Roquer J., Rosand J., and Rost NS Stroke; a journal of cerebral circulation, 2010/03/01, Volume 41, Issue 3, p.437-42, (2010) Read More / View Supplemental Materials
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Mining regulatory 5'UTRs from cDNA deep sequencing datasets.Livny, J., and Waldor MK Nucleic acids research, 2010/03/01, Volume 38, Issue 5, p.1504-14, (2010) Read More / View Supplemental Materials
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Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis.Gohil, VM, Sheth SA, Nilsson R., Wojtovich AP, Lee JH, Perocchi F., Chen W., Clish CB, and Mootha VK Nature biotechnology, 2010/03/01, Volume 28, Issue 3, p.249-55, (2010) Read More / View Supplemental Materials
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Rapid behavior-based identification of neuroactive small molecules in the zebrafish.Kokel, D., Bryan J., Laggner C., White R., Cheung CY, Mateus R., Healey D., Kim S., Werdich AA, Haggarty SJ, Macrae CA, Shoichet B., and Peterson RT Nature chemical biology, 2010/03/01, Volume 6, Issue 3, p.231-237, (2010) Read More / View Supplemental Materials
Abstract
Synthetic chemistry: An upfront investment.Young, DW Nature chemical biology, 2010/03/01, Volume 6, Issue 3, p.174-175, (2010) Read More / View Supplemental Materials
Unbiased identification of protein-bait interactions using biochemical enrichment and quantitative proteomics.Ong, SE Cold Spring Harbor protocols, 2010/03/01, Volume 2010, Issue 3, p.pdb.prot5400, (2010) Read More / View Supplemental Materials
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The landscape of somatic copy-number alteration across human cancers.Beroukhim, R., Mermel CH, Porter D., Wei G., Raychaudhuri S., Donovan J., Barretina J., Boehm JS, Dobson J., Urashima M., Mc Henry KT, Pinchback RM, Ligon AH, Cho YJ, Haery L., Greulich H., Reich M., Winckler W., Lawrence MS, Weir BA, et al. Nature, 2010/02/18, Volume 463, Issue 7283, p.899-905, (2010) Read More / View Supplemental Materials
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A composite of multiple signals distinguishes causal variants in regions of positive selection.Grossman, SR, Shylakhter I., Karlsson EK, Byrne EH, Morales S., Frieden G., Hostetter E., Angelino E., Garber M., Zuk O., Lander E. S., Schaffner SF, and Sabeti PC Science (New York, N.Y.), 2010/02/12, Volume 327, Issue 5967, p.883-6, (2010) Read More / View Supplemental Materials
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The fast track to multidrug resistance.Kaufmann, BB, and Hung DT Molecular cell, 2010/02/12, Volume 37, Issue 3, p.297-8, (2010) Read More / View Supplemental Materials
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Analysis of high-throughput sequencing and annotation strategies for phage genomes.Henn, MR, Sullivan MB, Stange-Thomann N., Osburne MS, Berlin AM, Kelly L., Yandava C., Kodira C., Zeng Q., Weiand M., Sparrow T., Saif S., Giannoukos G., Young SK, Nusbaum C., Birren BW, and Chisholm SW PloS one, 2010/02/05, Volume 5, Issue 2, p.e9083, (2010) Read More / View Supplemental Materials
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Repeatability and reproducibility in proteomic identifications by liquid chromatography-tandem mass spectrometry.Tabb, DL, Vega-Montoto L., Rudnick PA, Variyath AM, Ham AJ, Bunk DM, Kilpatrick LE, Billheimer DD, Blackman RK, Cardasis HL, Carr SA, Clauser KR, Jaffe JD, Kowalski KA, Neubert TA, Regnier FE, Schilling B., Tegeler TJ, Wang M., Wang P., et al. Journal of proteome research, 2010/02/05, Volume 9, Issue 2, p.761-76, (2010) Read More / View Supplemental Materials
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Replication and active demethylation represent partially overlapping mechanisms for erasure of H3K4me3 in budding yeast.Radman-Livaja, M., Liu CL, Friedman N., Schreiber SL, and Rando OJ PLoS genetics, 2010/02/05, Volume 6, Issue 2, p.e1000837, (2010) Read More / View Supplemental Materials
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A scalable, fully automated process for construction of sequence-ready barcoded libraries for 454.Lennon, NJ, Lintner RE, Anderson S., Alvarez P., Barry A., Brockman W., Daza R., Erlich RL, Giannoukos G., Green L., Hollinger A., Hoover CA, Jaffe DB, Juhn F., McCarthy D., Perrin D., Ponchner K., Powers TL, Rizzolo K., Robbins D., et al. Genome biology, 2010/02/05, Volume 11, Issue 2, p.R15, (2010) Read More / View Supplemental Materials
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Analytical validation of protein-based multiplex assays: a workshop report by the NCI-FDA interagency oncology task force on molecular diagnostics.Rodriguez, H., Tezak Z., Mesri M., Carr SA, Liebler DC, Fisher SJ, Tempst P., Hiltke T., Kessler LG, Kinsinger CR, Philip R., Ransohoff DF, Skates SJ, Regnier FE, Anderson NL, Mansfield E., and Workshop Participants Clinical chemistry, 2010/02/01, Volume 56, Issue 2, p.237-43, (2010) Read More / View Supplemental Materials
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Automated detection of inaccurate and imprecise transitions in peptide quantification by multiple reaction monitoring mass spectrometry.Abbatiello, SE, Mani D. R., Keshishian H., and Carr SA Clinical chemistry, 2010/02/01, Volume 56, Issue 2, p.291-305, (2010) Read More / View Supplemental Materials
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CK1epsilon is required for breast cancers dependent on beta-catenin activity.Kim, SY, Dunn IF, Firestein R., Gupta P., Wardwell L., Repich K., Schinzel AC, Wittner B., Silver SJ, Root DE, Boehm JS, Ramaswamy S., Lander E. S., and Hahn WC PloS one, 2010/02/01, Volume 5, Issue 2, p.e8979, (2010) Read More / View Supplemental Materials
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Genetic structure of a unique admixed population: implications for medical research.Patterson, N., Petersen DC, van der Ross RE, Sudoyo H., Glashoff RH, Marzuki S., Reich D., and Hayes VM Human molecular genetics, 2010/02/01, Volume 19, Issue 3, p.411-9, (2010) Read More / View Supplemental Materials
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Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.Saxena, R., Hivert MF, Langenberg C., Tanaka T., Pankow JS, Vollenweider P., Lyssenko V., Bouatia-Naji N., Dupuis J., Jackson AU, Kao WH, Li M., Glazer NL, Manning AK, Luan J., Stringham HM, Prokopenko I., Johnson T., Grarup N., Boesgaard TW, et al. Nature genetics, 2010/02/01, Volume 42, Issue 2, p.142-8, (2010) Read More / View Supplemental Materials
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Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution.Gu, H., Bock C., Mikkelsen TS, Jäger N., Smith ZD, Tomazou E., Gnirke A., Lander E. S., and Meissner A. Nature methods, 2010/02/01, Volume 7, Issue 2, p.133-6, (2010) Read More / View Supplemental Materials
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