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2004
Genetic dissection of complex traits with chromosome substitution strains of mice.Singer, JB, Hill AE, Burrage LC, Olszens KR, Song J., Justice M., O'Brien WE, Conti DV, Witte JS, Lander E. S., and Nadeau JH Science (New York, N.Y.), 2004/04/16, Volume 304, Issue 5669, p.445-8, (2004) Read More / View Supplemental Materials
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High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines.Jänne, PA, Li C., Zhao X., Girard L., Chen TH, Minna J., Christiani DC, Johnson B. E., and Meyerson M. Oncogene, 2004/04/08, Volume 23, Issue 15, p.2716-26, (2004) Read More / View Supplemental Materials
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Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae.Kellis, M., Birren BW, and Lander E. S. Nature, 2004/04/08, Volume 428, Issue 6983, p.617-24, (2004) Read More / View Supplemental Materials
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Assessing the impact of population stratification on genetic association studies.Freedman, ML, Reich D., Penney KL, McDonald GJ, Mignault AA, Patterson N., Gabriel SB, Topol EJ, Smoller JW, Pato CN, Pato MT, Petryshen TL, Kolonel LN, Lander E. S., Sklar P., Henderson B., Hirschhorn JN, and Altshuler D. Nature genetics, 2004/04/01, Volume 36, Issue 4, p.388-93, (2004) Read More / View Supplemental Materials
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Stuart Schreiber: biology from a chemist's perspective. Interview by Joanna Owens.Schreiber, SL Drug discovery today, 2004/04/01, Volume 9, Issue 7, p.299-303, (2004) Read More / View Supplemental Materials
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Metagenes and molecular pattern discovery using matrix factorizationBrunet, Jean-Philippe, Tamayo Pablo, Golub Todd R., and Mesirov Jill P. Proceedings of the National Academy of Sciences of the United States of America, 2004/03/23/, Volume 101, Issue 12, p.4164 - 9, (2004) Read More / View Supplemental Materials
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Metagenes and molecular pattern discovery using matrix factorization.Brunet, JP, Tamayo P., Golub T. R., and Mesirov J. P. Proceedings of the National Academy of Sciences of the United States of America, 2004/03/23, Volume 101, Issue 12, p.4164-9, (2004) Read More / View Supplemental Materials
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Synthetic strategy toward skeletal diversity via solid-supported, otherwise unstable reactive intermediates.Taylor, SJ, Taylor AM, and Schreiber SL Angewandte Chemie (International ed. in English), 2004/03/19, Volume 43, Issue 13, p.1681-5, (2004) Read More / View Supplemental Materials
Combining gene expression profiles and clinical parameters for risk stratification in medulloblastomasFernandez-Teijeiro, Ana, Betensky Rebecca A., Sturla Lisa M., Kim John Y. H., Tamayo Pablo, and Pomeroy Scott L. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 2004/03/15/, Volume 22, Issue 6, p.994 - 8, (2004) Read More / View Supplemental Materials
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Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation.Stegmaier, K., Ross KN, Colavito SA, O'Malley S., Stockwell BR, and Golub T. R. Nature genetics, 2004/03/01, Volume 36, Issue 3, p.257-63, (2004) Read More / View Supplemental Materials
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Rpd3p relocation mediates a transcriptional response to rapamycin in yeast.Humphrey, EL, Shamji AF, Bernstein BE, and Schreiber SL Chemistry & biology, 2004/03/01, Volume 11, Issue 3, p.295-9, (2004) Read More / View Supplemental Materials
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Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiationStegmaier, Kimberly, Ross Kenneth N., Colavito Sierra A., O'Malley Shawn, Stockwell Brent R., and Golub Todd R. Nature Genetics, 2004/03//, Volume 36, Issue 3, p.257 - 63, (2004) Read More / View Supplemental Materials
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Globally distributed object identification for biological knowledgebasesClark, Tim, Martin Sean, and Liefeld Ted Briefings in Bioinformatics, 2004/03//, Volume 5, Issue 1, p.59 - 70, (2004) Read More / View Supplemental Materials
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Macrolactones in diversity-oriented synthesis: preparation of a pilot library and exploration of factors controlling macrocyclization.Schmidt, DR, Kwon O., and Schreiber SL Journal of combinatorial chemistry, 2004/01/20, Volume 6, Issue 2, p.286-92, (2004) Read More / View Supplemental Materials
Loss of heterozygosity and its correlation with expression profiles in subclasses of invasive breast cancersWang, Zhigang C., Lin Ming, Wei Lee-Jen, Li Cheng, Miron Alexander, Lodeiro Gabriella, Harris Lyndsay, Ramaswamy Sridhar, Tanenbaum David M., Meyerson Matthew, Iglehart James D., and Richardson Andrea Cancer Research, 2004/01/01/, Volume 64, Issue 1, p.64 - 71, (2004) Read More / View Supplemental Materials
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Genome coverage and sequence fidelity of phi29 polymerase-based multiple strand displacement whole genome amplificationPaez, Guillermo J., Lin Ming, Beroukhim Rameen, Lee Jeffrey C., Zhao Xiaojun, Richter Daniel J., Gabriel Stacey, Herman Paula, Sasaki Hidefumi, Altshuler David, Li Cheng, Meyerson Matthew, and Sellers William R. Nucleic Acids Research, 2004///, Volume 32, Issue 9, p.e71 - e71, (2004) Read More / View Supplemental Materials
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2003
The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphomaSavage, Kerry J., Monti Stefano, Kutok Jeffery L., Cattoretti Giorgio, Neuberg Donna, de Leval Laurence, Kurtin Paul, Dal Cin Paola, Ladd Christine, Feuerhake Friedrich, Aguiar Ricardo C. T., Li Sigui, Salles Gilles, Berger Francoise, Jing Wen, and Pinkus Geraldin Blood, 2003/12/01/, Volume 102, Issue 12, p.3871 - 9, (2003) Read More / View Supplemental Materials
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Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondriaMootha, Vamsi K., Bunkenborg Jakob, Olsen Jesper V., Hjerrild Majbrit, Wisniewski Jacek R., Stahl Erich, Bolouri Marjan S., Ray Heta N., Sihag Smita, Kamal Michael, Patterson Nick, Lander Eric S., and Mann Matthias Cell, 2003/11/26/, Volume 115, Issue 5, p.629 - 40, (2003) Read More / View Supplemental Materials
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MLL-rearranged leukemias: insights from gene expression profilingArmstrong, Scott A., Golub Todd R., and Korsmeyer Stanley J. Seminars in Hematology, 2003/10//, Volume 40, Issue 4, p.268 - 73, (2003) Read More / View Supplemental Materials
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A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancerLamb, Justin, Ramaswamy Sridhar, Ford Heide L., Contreras Bernardo, Martinez Robert V., Kittrell Frances S., Zahnow Cynthia A., Patterson Nick, Golub Todd R., and Ewen Mark E. Cell, 2003/08/08/, Volume 114, Issue 3, p.323 - 34, (2003) Read More / View Supplemental Materials
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Discovery of an inhibitor of a transcription factor using small molecule microarrays and diversity-oriented synthesis.Koehler, AN, Shamji AF, and Schreiber SL Journal of the American Chemical Society, 2003/07/16, Volume 125, Issue 28, p.8420-1, (2003) Read More / View Supplemental Materials
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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetesMootha, Vamsi K., Lindgren Cecilia M., Eriksson Karl-Fredrik, Subramanian Aravind, Sihag Smita, Lehar Joseph, Puigserver Pere, Carlsson Emma, and Ridderstr Nature Genetics, 2003/07//, Volume 34, Issue 3, p.267 - 73, (2003) Read More / View Supplemental Materials
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Expanding the functional group compatibility of small-molecule microarrays: discovery of novel calmodulin ligands.Barnes-Seeman, D., Park SB, Koehler AN, and Schreiber SL Angewandte Chemie (International ed. in English), 2003/05/30, Volume 42, Issue 21, p.2376-9, (2003) Read More / View Supplemental Materials
DNA microarrays in breast cancer: the promise of personalised medicineRamaswamy, Sridhar, and Perou Charles M. Lancet, 2003/05/10/, Volume 361, Issue 9369, p.1576 - 7, (2003) Read More / View Supplemental Materials
Gene expression-based classification of malignant gliomas correlates better with survival than histological classificationNutt, Catherine L., Mani D. R., Betensky Rebecca A., Tamayo Pablo, Cairncross Gregory J., Ladd Christine, Pohl Ute, Hartmann Christian, McLaughlin Margaret E., Batchelor Tracy T., Black Peter M., von Deimling Andreas, Pomeroy Scott L., Golub Todd R., and Louis David N. Cancer Research, 2003/04/01/, Volume 63, Issue 7, p.1602 - 7, (2003) Read More / View Supplemental Materials
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Gene expression-based classification of malignant gliomas correlates better with survival than histological classificationNutt, Catherine L., Mani D. R., Betensky Rebecca A., Tamayo Pablo, Cairncross Gregory J., Ladd Christine, Pohl Ute, Hartmann Christian, McLaughlin Margaret E., Batchelor Tracy T., Black Peter M., von Deimling Andreas, Pomeroy Scott L., Golub Todd R., and Louis David N. Cancer Research, 2003/04/01/, Volume 63, Issue 7, p.1602 - 7, (2003) Read More / View Supplemental Materials
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Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomicsMootha, Vamsi K., Lepage Pierre, Miller Kathleen, Bunkenborg Jakob, Reich Michael, Hjerrild Majbrit, Delmonte Terrye, Villeneuve Amelie, Sladek Robert, Xu Fenghao, Mitchell Grant A., Morin Charles, Mann Matthias, Hudson Thomas J., Robinson Brian, and Rioux John D. Proceedings of the National Academy of Sciences of the United States of America, 2003/01/21/, Volume 100, Issue 2, p.605 - 10, (2003) Read More / View Supplemental Materials
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A molecular signature of metastasis in primary solid tumorsRamaswamy, Sridhar, Ross Ken N., Lander Eric S., and Golub Todd R. Nature Genetics, 2003/01//, Volume 33, Issue 1, p.49 - 54, (2003) Read More / View Supplemental Materials
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Estimating dataset size requirements for classifying DNA microarray dataMukherjee, Sayan, Tamayo Pablo, Rogers Simon, Rifkin Ryan, Engle Anna, Campbell Colin, Golub Todd R., and Mesirov Jill P. Journal of Computational Biology: A Journal of Computational Molecular Cell Biology, 2003///, Volume 10, Issue 2, p.119 - 42, (2003) Read More / View Supplemental Materials
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Genome-wide loss of heterozygosity analysis from laser capture microdissected prostate cancer using single nucleotide polymorphic allele (SNP) arrays and a novel bioinformatics platform Lieberfarb, Marshall E., Lin Ming, Lechpammer Mirna, Li Cheng, Tanenbaum David M., Febbo Phillip G., Wright Renee L., Shim Judy, Kantoff Philip W., Loda Massimo, Meyerson Matthew, and Sellers William R., Volume 63, Issue 16, p.4781-5, (2003) Read More / View Supplemental Materials
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Microarray Data Mining: Facing the ChallengesPiatetsky-Shapiro, Gregory, and Tamayo Pablo, Volume 5, Issue 2, (2003) Read More / View Supplemental Materials
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2002
Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cellsChen, Chang-Zheng, Li Min, de Graaf David, Monti Stefano, and G Proceedings of the National Academy of Sciences of the United States of America, 2002/11/26/, Volume 99, Issue 24, p.15468 - 73, (2002) Read More / View Supplemental Materials
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The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblastsLessnick, Stephen L., Dacwag Caroline S., and Golub Todd R. Cancer Cell, 2002/05//, Volume 1, Issue 4, p.393 - 401, (2002) Read More / View Supplemental Materials
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DNA microarrays in clinical oncologyRamaswamy, Sridhar, and Golub Todd R. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 2002/04/01/, Volume 20, Issue 7, p.1932 - 41, (2002) Read More / View Supplemental Materials
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Gene expression correlates of clinical prostate cancer behaviorSingh, Dinesh, Febbo Phillip G., Ross Kenneth, Jackson Donald G., Manola Judith, Ladd Christine, Tamayo Pablo, Renshaw Andrew A., D'Amico Anthony V., Richie Jerome P., Lander Eric S., Loda Massimo, Kantoff Philip W., Golub Todd R., and Sellers William R. Cancer Cell, 2002/03//, Volume 1, Issue 2, p.203 - 9, (2002) Read More / View Supplemental Materials
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Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemiaFerrando, Adolfo A., Neuberg Donna S., Staunton Jane, Loh Mignon L., Huard Christine, Raimondi Susana C., Behm Fred G., Pui Ching Hon, Downing James R., Gilliland Gary D., Lander Eric S., Golub Todd R., and Look Thomas A. Cancer Cell, 2002/02//, Volume 1, Issue 1, p.75 - 87, (2002) Read More / View Supplemental Materials
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Prediction of central nervous system embryonal tumour outcome based on gene expressionPomeroy, Scott L., Tamayo Pablo, Gaasenbeek Michelle, Sturla Lisa M., Angelo Michael, McLaughlin Margaret E., Kim John Y. H., Goumnerova Liliana C., Black Peter M., Lau Ching, Allen Jeffrey C., Zagzag David, Olson James M., Curran Tom, Wetmore Cynthia, and Biegel Jacly Nature, 2002/01/24/, Volume 415, Issue 6870, p.436 - 42, (2002) Read More / View Supplemental Materials
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Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learningShipp, Margaret A., Ross Ken N., Tamayo Pablo, Weng Andrew P., Kutok Jeffery L., Aguiar Ricardo C. T., Gaasenbeek Michelle, Angelo Michael, Reich Michael, Pinkus Geraldine S., Ray Tane S., Koval Margaret A., Last Kim W., Norton Andrew, Lister Andrew T., and Mesirov Jill Nature Medicine, 2002/01//, Volume 8, Issue 1, p.68 - 74, (2002) Read More / View Supplemental Materials
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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemiaArmstrong, Scott A., Staunton Jane E., Silverman Lewis B., Pieters Rob, den Boer Monique L., Minden Mark D., Sallan Stephen E., Lander Eric S., Golub Todd R., and Korsmeyer Stanley J. Nature Genetics, 2002/01//, Volume 30, Issue 1, p.41 - 7, (2002) Read More / View Supplemental Materials
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A strategy for oligonucleotide microarray probe reductionAntipova, Alena A., Tamayo Pablo, and Golub Todd R. Genome Biology, 2002///, Volume 3, Issue 12, p.RESEARCH0073 - RESEARCH0073, (2002) Read More / View Supplemental Materials
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Molecular Determinants of Lymph Node Metastasis in Breast CancerXuegong Zhang, Catherine Gradek, Robert Gentleman Igor Leykin Stefano Monti Sridhar Ramaswamy Wing Wong Todd Golub H. R. J., and Richardson Andrea L., 05/01/2002, (2002) Read More / View Supplemental Materials
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2001
Multiclass cancer diagnosis using tumor gene expression signaturesRamaswamy, S., Tamayo P., Rifkin R., Mukherjee S., Yeang C. H., Angelo M., Ladd C., Reich M., Latulippe E., Mesirov J. P., Poggio T., Gerald W., Loda M., Lander E. S., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2001/12/18/, Volume 98, Issue 26, p.15149 - 54, (2001) Read More / View Supplemental Materials
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A one-bead, one-stock solution approach to chemical genetics: part 2.Clemons, PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, and Foley MA Chemistry & biology, 2001/12/01, Volume 8, Issue 12, p.1183-95, (2001) Read More / View Supplemental Materials
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Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclassesBhattacharjee, A., Richards W. G., Staunton J., Li C., Monti S., Vasa P., Ladd C., Beheshti J., Bueno R., Gillette M., Loda M., Weber G., Mark E. J., Lander E. S., Wong W., Johnson B. E., Golub T. R., Sugarbaker D. J., and Meyerson M. Proceedings of the National Academy of Sciences of the United States of America, 2001/11/20/, Volume 98, Issue 24, p.13790 - 5, (2001) Read More / View Supplemental Materials
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Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclassesBhattacharjee, A., Richards W. G., Staunton J., Li C., Monti S., Vasa P., Ladd C., Beheshti J., Bueno R., Gillette M., Loda M., Weber G., Mark E. J., Lander E. S., Wong W., Johnson B. E., Golub T. R., Sugarbaker D. J., and Meyerson M. Proceedings of the National Academy of Sciences of the United States of America, 2001/11/20/, Volume 98, Issue 24, p.13790 - 5, (2001) Read More / View Supplemental Materials
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Chemosensitivity prediction by transcriptional profilingStaunton, J. E., Slonim D. K., Coller H. A., Tamayo P., Angelo M. J., Park J., Scherf U., Lee J. K., Reinhold W. O., Weinstein J. N., Mesirov J. P., Lander E. S., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2001/09/11/, Volume 98, Issue 19, p.10787 - 92, (2001) Read More / View Supplemental Materials
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c-Myc is a critical target for c/EBPalpha in granulopoiesisJohansen, L. M., Iwama A., Lodie T. A., Sasaki K., Felsher D. W., Golub T. R., and Tenen D. G. Molecular and Cellular Biology, 2001/06//, Volume 21, Issue 11, p.3789 - 806, (2001) Read More / View Supplemental Materials
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Genome-wide views of cancerGolub, T. R. The New England Journal of Medicine, 2001/02/22/, Volume 344, Issue 8, p.601 - 2, (2001) Read More / View Supplemental Materials
Genome-wide views of cancerGolub, T. R. The New England Journal of Medicine, 2001/02/22/, Volume 344, Issue 8, p.601 - 2, (2001) Read More / View Supplemental Materials
Molecular classification of multiple tumor typesYeang, C. H., Ramaswamy S., Tamayo P., Mukherjee S., Rifkin R. M., Angelo M., Reich M., Lander E., Mesirov J., and Golub T. Bioinformatics (Oxford, England), 2001///, Volume 17 Suppl 1, p.S316-22 - S316-22, (2001) Read More / View Supplemental Materials
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2000
Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arraysLindblad-Toh, K., Tanenbaum D. M., Daly M. J., Winchester E., Lui W. O., Villapakkam A., Stanton S. E., Larsson C., Hudson T. J., Johnson B. E., Lander E. S., and Meyerson M. Nature Biotechnology, 2000/09//, Volume 18, Issue 9, p.1001 - 5, (2000) Read More / View Supplemental Materials
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Genomic analysis of metastasis reveals an essential role for RhoCClark, E. A., Golub T. R., Lander E. S., and Hynes R. O. Nature, 2000/08/03/, Volume 406, Issue 6795, p.532 - 5, (2000) Read More / View Supplemental Materials
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Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesionColler, H. A., Grandori C., Tamayo P., Colbert T., Lander E. S., Eisenman R. N., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2000/03/28/, Volume 97, Issue 7, p.3260 - 5, (2000) Read More / View Supplemental Materials
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GENOMICS: Journey to the Center of BiologyLander, E. S., and Weinberg R. A. Science (New York, N.Y.), 2000/03/10/, Volume 287, Issue 5459, p.1777 - 82, (2000) Read More / View Supplemental Materials
1999
Molecular classification of cancer: class discovery and class prediction by gene expression monitoringGolub, T. R., Slonim D. K., Tamayo P., Huard C., Gaasenbeek M., Mesirov J. P., Coller H., Loh M. L., Downing J. R., Caligiuri M. A., Bloomfield C. D., and Lander E. S. Science (New York, N.Y.), 1999/10/15/, Volume 286, Issue 5439, p.531 - 7, (1999) Read More / View Supplemental Materials
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The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.Glasfeld, A., Koehler AN, Schumacher MA, and Brennan RG Journal of molecular biology, 1999/08/13, Volume 291, Issue 2, p.347-61, (1999) Read More / View Supplemental Materials
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Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genesFambrough, D., McClure K., Kazlauskas A., and Lander E. S. Cell, 1999/06/11/, Volume 97, Issue 6, p.727 - 41, (1999) Read More / View Supplemental Materials
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Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiationTamayo, P., Slonim D., Mesirov J., Zhu Q., Kitareewan S., Dmitrovsky E., Lander E. S., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 1999/03/16/, Volume 96, Issue 6, p.2907 - 12, (1999) Read More / View Supplemental Materials
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1969
Place of pattern in proteomic biomarker discovery.Gillette, MA, Mani D. R., and Carr SA Journal of proteome research, 2005/1/1, Volume 4, Issue 4, p.1143-54, (1969) Read More / View Supplemental Materials
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Large scale preparation of silicon-functionalized SynPhase Polystyrene lanterns for solid-phase synthesis.Ryba, TD, Depew KM, and Marcaurelle LA Journal of combinatorial chemistry, 1969/12/31, Volume 11, Issue 1, p.110-6, (1969) Read More / View Supplemental Materials
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Provoking progress: a new chapter.Siegel, V. Disease models & mechanisms, 1969/12/31, Volume 6, Issue 3, p.557-8, (1969) Read More / View Supplemental Materials
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Skeletal diversity in small-molecule synthesis using ligand-controlled catalysis.Gray, BL, and Schreiber SL Journal of combinatorial chemistry, 1969/12/31, Volume 9, Issue 6, p.1028-35, (1969) Read More / View Supplemental Materials
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Small molecule enhancers of rapamycin-induced TOR inhibition promote autophagy, reduce toxicity in Huntington's disease models and enhance killing of mycobacteria by macrophages.Floto, RA, Sarkar S., Perlstein EO, Kampmann B., Schreiber SL, and Rubinsztein DC Autophagy, 1969/12/31, Volume 3, Issue 6, p.620-2, (1969) Read More / View Supplemental Materials
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