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2005
GeneCruiser: a web service for the annotation of microarray dataLiefeld, Ted, Reich Michael, Gould Joshua, Zhang Peili, Tamayo Pablo, and Mesirov Jill P. Bioinformatics (Oxford, England), 2005/09/15/, Volume 21, Issue 18, p.3681 - 2, (2005) Read More / View Supplemental Materials
Abstract
GeneCruiser: a web service for the annotation of microarray data.Liefeld, T., Reich M., Gould J., Zhang P., Tamayo P., and Mesirov J. P. Bioinformatics (Oxford, England), 2005/09/15, Volume 21, Issue 18, p.3681-2, (2005) Read More / View Supplemental Materials
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A zebrafish bmyb mutation causes genome instability and increased cancer susceptibilityShepard, Jennifer L., Amatruda James F., Stern Howard M., Subramanian Aravind, Finkelstein David, Ziai James, Finley Rose K., Pfaff Kathleen L., Hersey Candace, Zhou Yi, Barut Bruce, Freedman Matthew, Lee Charles, Spitsbergen Jan, Neuberg Donna, and Weber Gerhard Proceedings of the National Academy of Sciences of the United States of America, 2005/09/13/, Volume 102, Issue 37, p.13194 - 9, (2005) Read More / View Supplemental Materials
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A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility.Shepard, JL, Amatruda JF, Stern HM, Subramanian A., Finkelstein D., Ziai J., Finley KR, Pfaff KL, Hersey C., Zhou Y., Barut B., Freedman M., Lee C., Spitsbergen J., Neuberg D., Weber G., Golub T. R., Glickman JN, Kutok JL, Aster J. C., et al. Proceedings of the National Academy of Sciences of the United States of America, 2005/09/13, Volume 102, Issue 37, p.13194-9, (2005) Read More / View Supplemental Materials
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A high-density screen for linkage in multiple sclerosis.Sawcer, S., Ban M., Maranian M., Yeo TW, Compston A., Kirby A., Daly M. J., De Jager PL, Walsh E., Lander E. S., Rioux JD, Hafler DA, Ivinson A., Rimmler J., Gregory SG, Schmidt S., Pericak-Vance MA, Akesson E., Hillert J., Datta P., et al. American journal of human genetics, 2005/09/01, Volume 77, Issue 3, p.454-67, (2005) Read More / View Supplemental Materials
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From solution-phase to solid-phase enyne metathesis: crossover in the relative performance of two commonly used ruthenium pre-catalysts.Brittain, DE, Gray BL, and Schreiber SL Chemistry (Weinheim an der Bergstrasse, Germany), 2005/08/19, Volume 11, Issue 17, p.5086-93, (2005) Read More / View Supplemental Materials
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NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypesFeuerhake, Friedrich, Kutok Jeffery L., Monti Stefano, Chen Wen, LaCasce Ann S., Cattoretti Giorgio, Kurtin Paul, Pinkus Geraldine S., de Leval Laurence, Harris Nancy L., Savage Kerry J., Neuberg Donna, Habermann Thomas M., Dalla-Favera Riccardo, Golub Todd R., and A Blood, 2005/08/15/, Volume 106, Issue 4, p.1392 - 9, (2005) Read More / View Supplemental Materials
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A haplotype-based case-control study of BRCA1 and sporadic breast cancer risk.Freedman, ML, Penney KL, Stram DO, Riley S., McKean-Cowdin R., Le Marchand L., Altshuler D., and Haiman CA Cancer research, 2005/08/15, Volume 65, Issue 16, p.7516-22, (2005) Read More / View Supplemental Materials
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NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes.Feuerhake, F., Kutok JL, Monti S., Chen W., LaCasce AS, Cattoretti G., Kurtin P., Pinkus GS, de Leval L., Harris NL, Savage KJ, Neuberg D., Habermann TM, Dalla-Favera R., Golub T. R., Aster J. C., and Shipp M. A. Blood, 2005/08/15, Volume 106, Issue 4, p.1392-9, (2005) Read More / View Supplemental Materials
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Assembly of polymorphic genomes: algorithms and application to Ciona savignyi.Vinson, JP, Jaffe DB, O'Neill K., Karlsson EK, Stange-Thomann N., Anderson S., Mesirov J. P., Satoh N., Satou Y., Nusbaum C., Birren B., Galagan JE, and Lander E. S. Genome research, 2005/08/01, Volume 15, Issue 8, p.1127-35, (2005) Read More / View Supplemental Materials
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Imaging biomarkers in drug development: an overview of opportunities and open issues.Chandra, S., Muir C., Silva M., and Carr S. Journal of proteome research, 2005/07/20, Volume 4, Issue 4, p.1134-7, (2005) Read More / View Supplemental Materials
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanomaGarraway, Levi A., Widlund Hans R., Rubin Mark A., Getz Gad, Berger Aaron J., Ramaswamy Sridhar, Beroukhim Rameen, Milner Danny A., Granter Scott R., Du Jinyan, Lee Charles, Wagner Stephan N., Li Cheng, Golub Todd R., Rimm David L., Meyerson Matthew L., and Fisher David Nature, 2005/07/07/, Volume 436, Issue 7047, p.117 - 22, (2005) Read More / View Supplemental Materials
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Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.Garraway, LA, Widlund HR, Rubin MA, Getz G., Berger AJ, Ramaswamy S., Beroukhim R., Milner DA, Granter SR, Du J., Lee C., Wagner SN, Li C., Golub T. R., Rimm DL, Meyerson ML, Fisher DE, and Sellers WR Nature, 2005/07/07, Volume 436, Issue 7047, p.117-22, (2005) Read More / View Supplemental Materials
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Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysisZhao, Xiaojun, Weir Barbara A., LaFramboise Thomas, Lin Ming, Beroukhim Rameen, Garraway Levi, Beheshti Javad, Lee Jeffrey C., Naoki Katsuhiko, Richards William G., Sugarbaker David, Chen Fei, Rubin Mark A., and J Cancer Research, 2005/07/01/, Volume 65, Issue 13, p.5561 - 70, (2005) Read More / View Supplemental Materials
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Association of DLG5 R30Q variant with inflammatory bowel disease.Daly, M. J., Pearce AV, Farwell L., Fisher SA, Latiano A., Prescott NJ, Forbes A., Mansfield J., Sanderson J., Langelier D., Cohen A., Bitton A., Wild G., Lewis CM, Annese V., Mathew CG, and Rioux JD European journal of human genetics : EJHG, 2005/07/01, Volume 13, Issue 7, p.835-9, (2005) Read More / View Supplemental Materials
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Small molecules: the missing link in the central dogma.Schreiber, SL Nature chemical biology, 2005/07/01, Volume 1, Issue 2, p.64-6, (2005) Read More / View Supplemental Materials
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Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer.Saji, S., Kawakami M., Hayashi S., Yoshida N., Hirose M., Horiguchi S., Itoh A., Funata N., Schreiber SL, Yoshida M., and Toi M. Oncogene, 2005/06/30, Volume 24, Issue 28, p.4531-9, (2005) Read More / View Supplemental Materials
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Small-molecule diversity using a skeletal transformation strategy.Kumar, N., Kiuchi M., Tallarico JA, and Schreiber SL Organic letters, 2005/06/23, Volume 7, Issue 13, p.2535-8, (2005) Read More / View Supplemental Materials
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An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarrayEbert, Benjamin L., Lee Michele M., Pretz Jennifer L., Subramanian Aravind, Mak Raymond, Golub Todd R., and Sieff Colin A. Blood, 2005/06/15/, Volume 105, Issue 12, p.4620 - 6, (2005) Read More / View Supplemental Materials
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An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarray.Ebert, BL, Lee MM, Pretz JL, Subramanian A., Mak R., Golub T. R., and Sieff CA Blood, 2005/06/15, Volume 105, Issue 12, p.4620-6, (2005) Read More / View Supplemental Materials
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Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma.Hideshima, T., Bradner JE, Wong J., Chauhan D., Richardson P., Schreiber SL, and Anderson KC Proceedings of the National Academy of Sciences of the United States of America, 2005/06/14, Volume 102, Issue 24, p.8567-72, (2005) Read More / View Supplemental Materials
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MicroRNA expression profiles classify human cancersLu, Jun, Getz Gad, Miska Eric A., Alvarez-Saavedra Ezequiel, Lamb Justin, Peck David, Sweet-Cordero Alejandro, Ebert Benjamin L., Mak Raymond H., Ferrando Adolfo A., Downing James R., Jacks Tyler, Horvitz Robert H., and Golub Todd R. Nature, 2005/06/09/, Volume 435, Issue 7043, p.834 - 8, (2005) Read More / View Supplemental Materials
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MicroRNA expression profiles classify human cancers.Lu, J., Getz G., Miska EA, Alvarez-Saavedra E., Lamb J., Peck D., Sweet-Cordero A., Ebert BL, Mak RH, Ferrando AA, Downing J. R., Jacks T., Horvitz HR, and Golub T. R. Nature, 2005/06/09, Volume 435, Issue 7043, p.834-8, (2005) Read More / View Supplemental Materials
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Distinct effectors of platelet-derived growth factor receptor-alpha signaling are required for cell survival during embryogenesis.Van Stry, M., Kazlauskas A., Schreiber SL, and Symes K. Proceedings of the National Academy of Sciences of the United States of America, 2005/06/07, Volume 102, Issue 23, p.8233-8, (2005) Read More / View Supplemental Materials
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Synthesis and biological evaluation of novel fumagillin and ovalicin analogues.Mazitschek, R., Huwe A., and Giannis A. Organic & biomolecular chemistry, 2005/06/07, Volume 3, Issue 11, p.2150-4, (2005) Read More / View Supplemental Materials
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Genetic association studies of complex traits: design and analysis issues.Newton-Cheh, C., and Hirschhorn JN Mutation research, 2005/06/03, Volume 573, Issue 1-2, p.54-69, (2005) Read More / View Supplemental Materials
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Paths to understanding the genetic basis of autoimmune disease.Rioux, JD, and Abbas AK Nature, 2005/06/02, Volume 435, Issue 7042, p.584-9, (2005) Read More / View Supplemental Materials
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The principle of complementarity: chemical versus biological space.Haggarty, SJ Current opinion in chemical biology, 2005/06/01, Volume 9, Issue 3, p.296-303, (2005) Read More / View Supplemental Materials
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Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer.Febbo, PG, Lowenberg M., Thorner AR, Brown M., Loda M., and Golub T. R. The Journal of urology, 2005/05/01, Volume 173, Issue 5, p.1772-7, (2005) Read More / View Supplemental Materials
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DNA polymorphism detector: an automated tool that searches for allelic matches in public databases for discrepancies found in clone or cDNA sequences.Chang, CY, and LaBaer J. Bioinformatics (Oxford, England), 2005/05/01, Volume 21, Issue 9, p.2133-5, (2005) Read More / View Supplemental Materials
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Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements.Ramanathan, A., Wang C., and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2005/04/26, Volume 102, Issue 17, p.5992-7, (2005) Read More / View Supplemental Materials
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Convergent diversity-oriented synthesis of small-molecule hybrids.Chen, C., Li X., Neumann CS, Lo MM, and Schreiber SL Angewandte Chemie (International ed. in English), 2005/04/08, Volume 44, Issue 15, p.2249-52, (2005) Read More / View Supplemental Materials
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.Levine, RL, Wadleigh M., Cools J., Ebert BL, Wernig G., Huntly BJ, Boggon TJ, Wlodarska I., Clark JJ, Moore S., Adelsperger J., Koo S., Lee JC, Gabriel S., Mercher T., D'Andrea A., Fröhling S., Döhner K., Marynen P., Vandenberghe P., et al. Cancer cell, 2005/04/01, Volume 7, Issue 4, p.387-97, (2005) Read More / View Supplemental Materials
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A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms.Miretti, MM, Walsh EC, Ke X., Delgado M., Griffiths M., Hunt S., Morrison J., Whittaker P., Lander E. S., Cardon LR, Bentley DR, Rioux JD, Beck S., and Deloukas P. American journal of human genetics, 2005/04/01, Volume 76, Issue 4, p.634-46, (2005) Read More / View Supplemental Materials
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Support for involvement of neuregulin 1 in schizophrenia pathophysiology.Petryshen, TL, Middleton FA, Kirby A., Aldinger KA, Purcell S., Tahl AR, Morley CP, McGann L., Gentile KL, Rockwell GN, Medeiros HM, Carvalho C., Macedo A., Dourado A., Valente J., Ferreira CP, Patterson NJ, Azevedo MH, Daly M. J., Pato CN, et al. Molecular psychiatry, 2005/04/01, Volume 10, Issue 4, p.366-74, 328, (2005) Read More / View Supplemental Materials
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An initial strategy for the systematic identification of functional elements in the human genome by low-redundancy comparative sequencing.Margulies, EH, Vinson JP, NISC Comparative Sequencing Program, Miller W., Jaffe DB, Lindblad-Toh K., Chang JL, Green ED, Lander E. S., Mullikin JC, and Clamp M. Proceedings of the National Academy of Sciences of the United States of America, 2005/03/29, Volume 102, Issue 13, p.4795-800, (2005) Read More / View Supplemental Materials
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Interacting genetic loci cause airway hyperresponsiveness.Ackerman, KG, Huang H., Grasemann H., Puma C., Singer JB, Hill AE, Lander E., Nadeau JH, Churchill GA, Drazen JM, and Beier DR Physiological genomics, 2005/03/21, Volume 21, Issue 1, p.105-11, (2005) Read More / View Supplemental Materials
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Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammalsXie, Xiaohui, Lu Jun, Kulbokas E. J., Golub Todd R., Mootha Vamsi, Lindblad-Toh Kerstin, Lander Eric S., and Kellis Manolis Nature, 2005/03/17/, Volume 434, Issue 7031, p.338 - 45, (2005) Read More / View Supplemental Materials
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Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals.Xie, X., Lu J., Kulbokas E. J., Golub T. R., Mootha V., Lindblad-Toh K., Lander E. S., and Kellis M. Nature, 2005/03/17, Volume 434, Issue 7031, p.338-45, (2005) Read More / View Supplemental Materials
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Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory responseMonti, Stefano, Savage Kerry J., Kutok Jeffery L., Feuerhake Friedrich, Kurtin Paul, Mihm Martin, Wu Bingyan, Pasqualucci Laura, Neuberg Donna, Aguiar Ricardo C. T., Dal Cin Paola, Ladd Christine, Pinkus Geraldine S., Salles Gilles, Harris Nancy Lee, and Dalla-Fave Blood, 2005/03/01/, Volume 105, Issue 5, p.1851 - 61, (2005) Read More / View Supplemental Materials
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Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response.Monti, S., Savage KJ, Kutok JL, Feuerhake F., Kurtin P., Mihm M., Wu B., Pasqualucci L., Neuberg D., Aguiar RC, Dal Cin P., Ladd C., Pinkus GS, Salles G., Harris NL, Dalla-Favera R., Habermann TM, Aster J. C., Golub T. R., and Shipp M. A. Blood, 2005/03/01, Volume 105, Issue 5, p.1851-61, (2005) Read More / View Supplemental Materials
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Genetics. Harvesting medical information from the human family tree.Altshuler, D., and Clark AG Science (New York, N.Y.), 2005/02/18, Volume 307, Issue 5712, p.1052-3, (2005) Read More / View Supplemental Materials
Improving genome annotations using phylogenetic profile anomaly detection.Mikkelsen, TS, Galagan JE, and Mesirov J. P. Bioinformatics (Oxford, England), 2005/02/15, Volume 21, Issue 4, p.464-70, (2005) Read More / View Supplemental Materials
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Genome-wide association studies for common diseases and complex traits.Hirschhorn, JN, and Daly M. J. Nature reviews. Genetics, 2005/02/01, Volume 6, Issue 2, p.95-108, (2005) Read More / View Supplemental Materials
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How old is the most recent ancestor of two copies of an allele?Patterson, NJ Genetics, 2005/02/01, Volume 169, Issue 2, p.1093-104, (2005) Read More / View Supplemental Materials
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Mapping quantitative trait loci for anxiety in chromosome substitution strains of mice.Singer, JB, Hill AE, Nadeau JH, and Lander E. S. Genetics, 2005/02/01, Volume 169, Issue 2, p.855-62, (2005) Read More / View Supplemental Materials
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Using genome-wide transcriptional profiling to elucidate small-molecule mechanism.Butcher, RA, and Schreiber SL Current opinion in chemical biology, 2005/02/01, Volume 9, Issue 1, p.25-30, (2005) Read More / View Supplemental Materials
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Genomic maps and comparative analysis of histone modifications in human and mouse.Bernstein, BE, Kamal M., Lindblad-Toh K., Bekiranov S., Bailey DK, Huebert DJ, McMahon S., Karlsson EK, Kulbokas EJ 3rd, Gingeras TR, Schreiber SL, and Lander E. S. Cell, 2005/01/28, Volume 120, Issue 2, p.169-81, (2005) Read More / View Supplemental Materials
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Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.Wang, J., Iwasaki H., Krivtsov A., Febbo PG, Thorner AR, Ernst P., Anastasiadou E., Kutok JL, Kogan SC, Zinkel SS, Fisher JK, Hess JL, Golub T. R., Armstrong SA, Akashi K., and Korsmeyer SJ The EMBO journal, 2005/01/26, Volume 24, Issue 2, p.368-81, (2005) Read More / View Supplemental Materials
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Skeletal diversity via a folding pathway: synthesis of indole alkaloid-like skeletons.Oguri, H., and Schreiber SL Organic letters, 2005/01/06, Volume 7, Issue 1, p.47-50, (2005) Read More / View Supplemental Materials
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Mapping posttranslational modifications of proteins by MS-based selective detection: application to phosphoproteomics.Carr, SA, Annan RS, and Huddleston MJ Methods in enzymology, 2005/01/01, Volume 405, p.82-115, (2005) Read More / View Supplemental Materials
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An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis.Sweet-Cordero, A., Mukherjee S., Subramanian A., You H., Roix JJ, Ladd-Acosta C., Mesirov J., Golub T. R., and Jacks T. Nature genetics, 2005/01/01, Volume 37, Issue 1, p.48-55, (2005) Read More / View Supplemental Materials
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An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysisSweet-Cordero, Alejandro, Mukherjee Sayan, Subramanian Aravind, You Han, Roix Jeffrey J., Ladd-Acosta Christine, Mesirov Jill, Golub Todd R., and Jacks Tyler Nature Genetics, 2005/01//, Volume 37, Issue 1, p.48 - 55, (2005) Read More / View Supplemental Materials
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Identifying biologically active compound classes using phenotypic screening data and sampling statistics.Klekota, J., Brauner E., and Schreiber SL Journal of chemical information and modeling, 1969/12/31, Volume 45, Issue 6, p.1824-36, (2005) Read More / View Supplemental Materials
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2004
Identification of AML1-ETO Modulators with Chemical GenomicsCorsello, Steven M., Roti Giovanni, Ross Kenneth N., Chow Kwan T., Golub Todd R., and Stegmaier Kimberly, unknown, (2004) Read More / View Supplemental Materials
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Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells.Berger, R., Febbo PG, Majumder PK, Zhao JJ, Mukherjee S., Signoretti S., Campbell KT, Sellers WR, Roberts TM, Loda M., Golub T. R., and Hahn WC Cancer research, 2004/12/15, Volume 64, Issue 24, p.8867-75, (2004) Read More / View Supplemental Materials
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A library of spirooxindoles based on a stereoselective three-component coupling reaction.Lo, MM, Neumann CS, Nagayama S., Perlstein EO, and Schreiber SL Journal of the American Chemical Society, 2004/12/15, Volume 126, Issue 49, p.16077-86, (2004) Read More / View Supplemental Materials
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Program to improve cognitive functioning in patients with schizophrenia: reflections.Scolnick, E. Schizophrenia research, 2004/12/15, Volume 72, Issue 1, p.75-7, (2004) Read More / View Supplemental Materials
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Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF.Du, J., Widlund HR, Horstmann MA, Ramaswamy S., Ross K., Huber WE, Nishimura EK, Golub T. R., and Fisher DE Cancer cell, 2004/12/01, Volume 6, Issue 6, p.565-76, (2004) Read More / View Supplemental Materials
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Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips.Huang, J., Zhu H., Haggarty SJ, Spring DR, Hwang H., Jin F., Snyder M., and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2004/11/23, Volume 101, Issue 47, p.16594-9, (2004) Read More / View Supplemental Materials
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Relationship of stereochemical and skeletal diversity of small molecules to cellular measurement space.Kim, YK, Arai MA, Arai T., Lamenzo JO, Dean EF 3rd, Patterson N., Clemons PA, and Schreiber SL Journal of the American Chemical Society, 2004/11/17, Volume 126, Issue 45, p.14740-5, (2004) Read More / View Supplemental Materials
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Stereochemical control of the Passerini reaction.Andreana, PR, Liu CC, and Schreiber SL Organic letters, 2004/11/11, Volume 6, Issue 23, p.4231-3, (2004) Read More / View Supplemental Materials
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A synthesis strategy yielding skeletally diverse small molecules combinatorially.Burke, MD, Berger EM, and Schreiber SL Journal of the American Chemical Society, 2004/11/03, Volume 126, Issue 43, p.14095-104, (2004) Read More / View Supplemental Materials
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A complex interaction of imprinted and maternal-effect genes modifies sex determination in Odd Sex (Ods) mice.Poirier, C., Qin Y., Adams CP, Anaya Y., Singer JB, Hill AE, Lander E. S., Nadeau JH, and Bishop CE Genetics, 2004/11/01, Volume 168, Issue 3, p.1557-62, (2004) Read More / View Supplemental Materials
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Genomewide search and association studies in a Finnish celiac disease population: Identification of a novel locus and replication of the HLA and CTLA4 loci.Rioux, JD, Karinen H., Kocher K., McMahon SG, Kärkkäinen P., Janatuinen E., Heikkinen M., Julkunen R., Pihlajamäki J., Naukkarinen A., Kosma VM, Daly M. J., Lander E. S., and Laakso M. American journal of medical genetics. Part A, 2004/11/01, Volume 130A, Issue 4, p.345-50, (2004) Read More / View Supplemental Materials
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Mapping chemical space using molecular descriptors and chemical genetics: deacetylase inhibitors.Haggarty, SJ, Clemons PA, Wong JC, and Schreiber SL Combinatorial chemistry & high throughput screening, 2004/11/01, Volume 7, Issue 7, p.669-76, (2004) Read More / View Supplemental Materials
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Syntheses of stereochemically diverse nine-membered ring-containing biaryls.Krishnan, S., and Schreiber SL Organic letters, 2004/10/28, Volume 6, Issue 22, p.4021-4, (2004) Read More / View Supplemental Materials
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Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype.Jaillon, O., Aury JM, Brunet F., Petit JL, Stange-Thomann N., Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S., Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C., Salanoubat M., Levy M., Boudet N., et al. Nature, 2004/10/21, Volume 431, Issue 7011, p.946-57, (2004) Read More / View Supplemental Materials
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Common variation in BRCA2 and breast cancer risk: a haplotype-based analysis in the Multiethnic Cohort.Freedman, ML, Penney KL, Stram DO, Le Marchand L., Hirschhorn JN, Kolonel LN, Altshuler D., Henderson BE, and Haiman CA Human molecular genetics, 2004/10/15, Volume 13, Issue 20, p.2431-41, (2004) Read More / View Supplemental Materials
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Transgenic rescue demonstrates involvement of the Ian5 gene in T cell development in the rat.Michalkiewicz, M., Michalkiewicz T., Ettinger RA, Rutledge EA, Fuller JM, Moralejo DH, Van Yserloo B., MacMurray AJ, Kwitek AE, Jacob HJ, Lander E. S., and Lernmark A. Physiological genomics, 2004/10/04, Volume 19, Issue 2, p.228-32, (2004) Read More / View Supplemental Materials
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Chromosomes 6 and 13 harbor genes that regulate pubertal timing in mouse chromosome substitution strains.Krewson, TD, Supelak PJ, Hill AE, Singer JB, Lander E. S., Nadeau JH, and Palmert MR Endocrinology, 2004/10/01, Volume 145, Issue 10, p.4447-51, (2004) Read More / View Supplemental Materials
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Transcriptional regulatory code of a eukaryotic genome.Harbison, CT, Gordon DB, Lee TI, Rinaldi NJ, Macisaac KD, Danford TW, Hannett NM, Tagne JB, Reynolds DB, Yoo J., Jennings EG, Zeitlinger J., Pokholok DK, Kellis M., Rolfe PA, Takusagawa KT, Lander E. S., Gifford DK, Fraenkel E., and Young RA Nature, 2004/09/02, Volume 431, Issue 7004, p.99-104, (2004) Read More / View Supplemental Materials
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Enhancing linkage analysis of complex disorders: an evaluation of high-density genotyping.Sawcer, SJ, Maranian M., Singlehurst S., Yeo T., Compston A., Daly M. J., De Jager PL, Gabriel S., Hafler DA, Ivinson AJ, Lander E. S., Rioux JD, Walsh E., Gregory SG, Schmidt S., Pericak-Vance MA, Barcellos L., Hauser SL, Oksenberg JR, Kenealy SJ, et al. Human molecular genetics, 2004/09/01, Volume 13, Issue 17, p.1943-9, (2004) Read More / View Supplemental Materials
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Eric S. Lander.Lander, E. S. Nature reviews. Drug discovery, 2004/09/01, Volume 3, Issue 9, p.730, (2004) Read More / View Supplemental Materials
Modular synthesis and preliminary biological evaluation of stereochemically diverse 1,3-dioxanes.Wong, JC, Sternson SM, Louca JB, Hong R., and Schreiber SL Chemistry & biology, 2004/09/01, Volume 11, Issue 9, p.1279-91, (2004) Read More / View Supplemental Materials
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RIP: the evolutionary cost of genome defense.Galagan, JE, and Selker EU Trends in genetics : TIG, 2004/09/01, Volume 20, Issue 9, p.417-23, (2004) Read More / View Supplemental Materials
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SNP genotyping using Sequenom MassARRAY 7K platform.Gabriel, S., and Ziaugra L. Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.], 2004/09/01, Volume Chapter 2, p.Unit 2.12, (2004) Read More / View Supplemental Materials
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Genomic approaches to hematologic malignanciesEbert, Benjamin L., and Golub Todd R. Blood, 2004/08/15/, Volume 104, Issue 4, p.923 - 32, (2004) Read More / View Supplemental Materials
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Genomic approaches to hematologic malignancies.Ebert, BL, and Golub T. R. Blood, 2004/08/15, Volume 104, Issue 4, p.923-32, (2004) Read More / View Supplemental Materials
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Toward a functional taxonomy of cancer.Golub, T. R. Cancer cell, 2004/08/01, Volume 6, Issue 2, p.107-8, (2004) Read More / View Supplemental Materials
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GeneCluster 2.0: an advanced toolset for bioarray analysisReich, M., Ohm K., Angelo M., Tamayo P., and Mesirov J. P. Bioinformatics (Oxford, England), 2004/07/22/, Volume 20, Issue 11, p.1797 - 8, (2004) Read More / View Supplemental Materials
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GeneCluster 2.0: an advanced toolset for bioarray analysis.Reich, M., Ohm K., Angelo M., Tamayo P., and Mesirov J. P. Bioinformatics (Oxford, England), 2004/07/22, Volume 20, Issue 11, p.1797-8, (2004) Read More / View Supplemental Materials
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Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids.Tantisira, KG, Lake S., Silverman ES, Palmer LJ, Lazarus R., Silverman EK, Liggett SB, Gelfand EW, Rosenwasser LJ, Richter B., Israel E., Wechsler M., Gabriel S., Altshuler D., Lander E., Drazen J., and Weiss ST Human molecular genetics, 2004/07/01, Volume 13, Issue 13, p.1353-9, (2004) Read More / View Supplemental Materials
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Molecular characterization of the tumor microenvironment in breast cancerAllinen, Minna, Beroukhim Rameen, Cai Li, Brennan Cameron, Lahti-Domenici Jaana, Huang Haiyan, Porter Dale, Hu Min, Chin Lynda, Richardson Andrea, Schnitt Stuart, Sellers William R., and Polyak Kornelia Cancer Cell, 2004/07//, Volume 6, Issue 1, p.17 - 32, (2004) Read More / View Supplemental Materials
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A transcriptional profiling study of CCAAT/enhancer binding protein targets identifies hepatocyte nuclear factor 3 beta as a novel tumor suppressor in lung cancerHalmos, Balazs, and Bass Cancer Research, 2004/06/15/, Volume 64, Issue 12, p.4137 - 47, (2004) Read More / View Supplemental Materials
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A transcriptional profiling study of CCAAT/enhancer binding protein targets identifies hepatocyte nuclear factor 3 beta as a novel tumor suppressor in lung cancer.Halmos, B., Bassères DS, Monti S., D'Aló F., Dayaram T., Ferenczi K., Wouters BJ, Huettner CS, Golub T. R., and Tenen D. G. Cancer research, 2004/06/15, Volume 64, Issue 12, p.4137-47, (2004) Read More / View Supplemental Materials
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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.Paez, JG, Jänne PA, Lee JC, Tracy S., Greulich H., Gabriel S., Herman P., Kaye FJ, Lindeman N., Boggon TJ, Naoki K., Sasaki H., Fujii Y., Eck MJ, Sellers WR, Johnson B. E., and Meyerson M. Science (New York, N.Y.), 2004/06/04, Volume 304, Issue 5676, p.1497-500, (2004) Read More / View Supplemental Materials
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Complex phenotypic assays in high-throughput screening.Clemons, PA Current opinion in chemical biology, 2004/06/01, Volume 8, Issue 3, p.334-8, (2004) Read More / View Supplemental Materials
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mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.Majumder, PK, Febbo PG, Bikoff R., Berger R., Xue Q., McMahon LM, Manola J., Brugarolas J., McDonnell TJ, Golub T. R., Loda M., Lane HA, and Sellers WR Nature medicine, 2004/06/01, Volume 10, Issue 6, p.594-601, (2004) Read More / View Supplemental Materials
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Selective detection of glycopeptides on ion trap mass spectrometers.Sullivan, B., Addona TA, and Carr SA Analytical chemistry, 2004/06/01, Volume 76, Issue 11, p.3112-8, (2004) Read More / View Supplemental Materials
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Identification of Ald6p as the target of a class of small-molecule suppressors of FK506 and their use in network dissection.Butcher, RA, and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2004/05/25, Volume 101, Issue 21, p.7868-73, (2004) Read More / View Supplemental Materials
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dChipSNP: significance curve and clustering of SNP-array-based loss-of-heterozygosity dataLin, Ming, Wei Lee-Jen, Sellers William R., Lieberfarb Marshall, Wong Wing Hung, and Li Cheng Bioinformatics (Oxford, England), 2004/05/22/, Volume 20, Issue 8, p.1233 - 40, (2004) Read More / View Supplemental Materials
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An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arraysZhao, Xiaojun, Li Cheng, Paez Guillermo J., Chin Koei, and J Cancer Research, 2004/05/01/, Volume 64, Issue 9, p.3060 - 71, (2004) Read More / View Supplemental Materials
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Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation.Peterson, RT, Shaw SY, Peterson TA, Milan DJ, Zhong TP, Schreiber SL, Macrae CA, and Fishman MC Nature biotechnology, 2004/05/01, Volume 22, Issue 5, p.595-9, (2004) Read More / View Supplemental Materials
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The Ensembl computing architecture.Cuff, JA, Coates GM, Cutts TJ, and Rae M. Genome research, 2004/05/01, Volume 14, Issue 5, p.971-5, (2004) Read More / View Supplemental Materials
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Methods for high-density admixture mapping of disease genes.Patterson, N., Hattangadi N., Lane B., Lohmueller KE, Hafler DA, Oksenberg JR, Hauser SL, Smith MW, O'Brien SJ, Altshuler D., Daly M. J., and Reich D. American journal of human genetics, 2004/05/01, Volume 74, Issue 5, p.979-1000, (2004) Read More / View Supplemental Materials
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Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscleMootha, Vamsi K., Handschin Christoph, Arlow Dan, Xie Xiaohui, St Pierre Julie, Sihag Smita, Yang Wenli, Altshuler David, Puigserver Pere, Patterson Nick, Willy Patricia J., Schulman Ira G., Heyman Richard A., Lander Eric S., and Spiegelman Bruce M. Proceedings of the National Academy of Sciences of the United States of America, 2004/04/27/, Volume 101, Issue 17, p.6570 - 5, (2004) Read More / View Supplemental Materials
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The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1Coletta, Ricardo D., Christensen Kimberly, Reichenberger Kelly J., Lamb Justin, Micomonaco Damian, Huang Lili, Wolf Douglas M., and M Proceedings of the National Academy of Sciences of the United States of America, 2004/04/27/, Volume 101, Issue 17, p.6478 - 83, (2004) Read More / View Supplemental Materials
Abstract
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle.Mootha, VK, Handschin C., Arlow D., Xie X., St Pierre J., Sihag S., Yang W., Altshuler D., Puigserver P., Patterson N., Willy PJ, Schulman IG, Heyman RA, Lander E. S., and Spiegelman BM Proceedings of the National Academy of Sciences of the United States of America, 2004/04/27, Volume 101, Issue 17, p.6570-5, (2004) Read More / View Supplemental Materials
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The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1.Coletta, RD, Christensen K., Reichenberger KJ, Lamb J., Micomonaco D., Huang L., Wolf DM, Müller-Tidow C., Golub T. R., Kawakami K., and Ford HL Proceedings of the National Academy of Sciences of the United States of America, 2004/04/27, Volume 101, Issue 17, p.6478-83, (2004) Read More / View Supplemental Materials
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