Scientific Publications

Search by Keyword(s)
Found 1595 results

Search Results

2009
Ultrasome: efficient aberration caller for copy number studies of ultra-high resolution.Nilsson, B., Johansson M., Al-Shahrour F., Carpenter AE, and Ebert BL Bioinformatics (Oxford, England), 2009/04/15, Volume 25, Issue 8, p.1078-9, (2009) Read More / View Supplemental Materials
Abstract
Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells.Borowiak, M., Maehr R., Chen S., Chen AE, Tang W., Fox JL, Schreiber SL, and Melton DA Cell stem cell, 2009/04/03, Volume 4, Issue 4, p.348-58, (2009) Read More / View Supplemental Materials
Abstract
Skeletally diverse small molecules using a build/couple/pair strategy.Uchida, T., Rodriquez M., and Schreiber SL Organic letters, 2009/04/02, Volume 11, Issue 7, p.1559-62, (2009) Read More / View Supplemental Materials
Abstract
Common genetic variants on chromosome 9p21 confers risk of ischemic stroke: a large-scale genetic association study.Smith, JG, Melander O., Lövkvist H., Hedblad B., Engström G., Nilsson P., Carlson J., Berglund G., Norrving B., and Lindgren A. Circulation. Cardiovascular genetics, 2009/04/01, Volume 2, Issue 2, p.159-64, (2009) Read More / View Supplemental Materials
Abstract
Common polymorphic transcript variation in human disease.Fraser, HB, and Xie X. Genome research, 2009/04/01, Volume 19, Issue 4, p.567-75, (2009) Read More / View Supplemental Materials
Abstract
MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes.Ikeda, S., He A., Kong SW, Lu J., Bejar R., Bodyak N., Lee KH, Ma Q., Kang PM, Golub T. R., and Pu WT Molecular and cellular biology, 2009/04/01, Volume 29, Issue 8, p.2193-204, (2009) Read More / View Supplemental Materials
Abstract
A small molecule that directs differentiation of human ESCs into the pancreatic lineage.Chen, S., Borowiak M., Fox JL, Maehr R., Osafune K., Davidow L., Lam K., Peng LF, Schreiber SL, Rubin LL, and Melton D. Nature chemical biology, 2009/04/01, Volume 5, Issue 4, p.258-65, (2009) Read More / View Supplemental Materials
Abstract
Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries.Kelly, KA, Shaw SY, Nahrendorf M., Kristoff K., Aikawa E., Schreiber SL, Clemons PA, and Weissleder R. Integrative biology : quantitative biosciences from nano to macro, 2009/04/01, Volume 1, Issue 4, p.311-7, (2009) Read More / View Supplemental Materials
Abstract
Identifying the proteins to which small-molecule probes and drugs bind in cells.Ong, SE, Schenone M., Margolin AA, Li X., Do K., Doud MK, Mani D. R., Kuai L., Wang X., Wood JL, Tolliday NJ, Koehler AN, Marcaurelle LA, Golub T. R., Gould RJ, Schreiber SL, and Carr SA Proceedings of the National Academy of Sciences of the United States of America, 2009/03/24, Volume 106, Issue 12, p.4617-22, (2009) Read More / View Supplemental Materials
Abstract
Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation.Salvesen, HB, Carter SL, Mannelqvist M., Dutt A., Getz G., Stefansson IM, Raeder MB, Sos ML, Engelsen IB, Trovik J., Wik E., Greulich H., Bø TH, Jonassen I., Thomas RK, Zander T., Garraway LA, Oyan AM, Sellers WR, Kalland KH, et al. Proceedings of the National Academy of Sciences of the United States of America, 2009/03/24, Volume 106, Issue 12, p.4834-9, (2009) Read More / View Supplemental Materials
Abstract
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling.Mao, Y., Ge X., Frank CL, Madison JM, Koehler AN, Doud MK, Tassa C., Berry EM, Soda T., Singh KK, Biechele T., Petryshen TL, Moon RT, Haggarty SJ, and Tsai LH Cell, 2009/03/20, Volume 136, Issue 6, p.1017-31, (2009) Read More / View Supplemental Materials
Abstract
Synthesis and histone deacetylase inhibitory activity of largazole analogs: alteration of the zinc-binding domain and macrocyclic scaffold.Bowers, AA, West N., Newkirk TL, Troutman-Youngman AE, Schreiber SL, Wiest O., Bradner JE, and Williams RM Organic letters, 2009/03/19, Volume 11, Issue 6, p.1301-4, (2009) Read More / View Supplemental Materials
Abstract
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals.Guttman, M., Amit I., Garber M., French C., Lin MF, Feldser D., Huarte M., Zuk O., Carey BW, Cassady JP, Cabili MN, Jaenisch R., Mikkelsen TS, Jacks T., Hacohen N., Bernstein BE, Kellis M., Regev A., Rinn JL, and Lander E. S. Nature, 2009/03/12, Volume 458, Issue 7235, p.223-7, (2009) Read More / View Supplemental Materials
Abstract
Prolonged therapy for hepatitis C with low-dose peginterferon.Hoshida, Y., and Golub T. R. The New England journal of medicine, 2009/03/12, Volume 360, Issue 11, p.1152; author reply 1152-3, (2009) Read More / View Supplemental Materials
Synthesis and conformation-activity relationships of the peptide isosteres of FK228 and largazole.Bowers, AA, Greshock TJ, West N., Estiu G., Schreiber SL, Wiest O., Williams RM, and Bradner JE Journal of the American Chemical Society, 2009/03/04, Volume 131, Issue 8, p.2900-5, (2009) Read More / View Supplemental Materials
Abstract
A small molecule that binds Hedgehog and blocks its signaling in human cells.Stanton, BZ, Peng LF, Maloof N., Nakai K., Wang X., Duffner JL, Taveras KM, Hyman JM, Lee SW, Koehler AN, Chen JK, Fox JL, Mandinova A., and Schreiber SL Nature chemical biology, 2009/03/01, Volume 5, Issue 3, p.154-6, (2009) Read More / View Supplemental Materials
Abstract
Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning.Jones, TR, Carpenter AE, Lamprecht MR, Moffat J., Silver SJ, Grenier JK, Castoreno AB, Eggert US, Root DE, Golland P., and Sabatini DM Proceedings of the National Academy of Sciences of the United States of America, 2009/02/10, Volume 106, Issue 6, p.1826-31, (2009) Read More / View Supplemental Materials
Abstract
Prediction of high-responding peptides for targeted protein assays by mass spectrometry.Fusaro, VA, Mani D. R., Mesirov J. P., and Carr SA Nature biotechnology, 2009/02/01, Volume 27, Issue 2, p.190-8, (2009) Read More / View Supplemental Materials
Abstract
Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing.Gnirke, A., Melnikov A., Maguire J., Rogov P., LeProust EM, Brockman W., Fennell T., Giannoukos G., Fisher S., Russ C., Gabriel S., Jaffe DB, Lander E. S., and Nusbaum C. Nature biotechnology, 2009/02/01, Volume 27, Issue 2, p.182-9, (2009) Read More / View Supplemental Materials
Abstract
Organic chemistry: Molecular diversity by design.Schreiber, SL Nature, 2009/01/08, Volume 457, Issue 7226, p.153-4, (2009) Read More / View Supplemental Materials
The state of the art of chemical biology.Altmann, KH, Buchner J., Kessler H., Diederich F., Kräutler B., Lippard S., Liskamp R., Müller K., Nolan EM, Samori B., Schneider G., Schreiber SL, Schwalbe H., Toniolo C., van Boeckel CA, Waldmann H., and Walsh CT Chembiochem : a European journal of chemical biology, 2009/01/05, Volume 10, Issue 1, p.16-29, (2009) Read More / View Supplemental Materials
ALLPATHS 2: small genomes assembled accurately and with high continuity from short paired reads.Maccallum, I., Przybylski D., Gnerre S., Burton J., Shlyakhter I., Gnirke A., Malek J., McKernan K., Ranade S., Shea TP, Williams L., Young S., Nusbaum C., and Jaffe DB Genome biology, 2009/01/01, Volume 10, Issue 10, p.R103, (2009) Read More / View Supplemental Materials
Abstract
Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy.Du, J., Bernasconi P., Clauser KR, Mani D. R., Finn SP, Beroukhim R., Burns M., Julian B., Peng XP, Hieronymus H., Maglathlin RL, Lewis TA, Liau LM, Nghiemphu P., Mellinghoff IK, Louis DN, Loda M., Carr SA, Kung AL, and Golub T. R. Nature biotechnology, 2009/01/01, Volume 27, Issue 1, p.77-83, (2009) Read More / View Supplemental Materials
Abstract
Closing gaps in the human genome using sequencing by synthesis.Garber, M., Zody MC, Arachchi HM, Berlin A., Gnerre S., Green LM, Lennon N., and Nusbaum C. Genome biology, 2009/01/01, Volume 10, Issue 6, p.R60, (2009) Read More / View Supplemental Materials
Abstract
High-resolution mapping of copy-number alterations with massively parallel sequencing.Chiang, DY, Getz G., Jaffe DB, O'Kelly MJ, Zhao X., Carter SL, Russ C., Nusbaum C., Meyerson M., and Lander E. S. Nature methods, 2009/01/01, Volume 6, Issue 1, p.99-103, (2009) Read More / View Supplemental Materials
Abstract
Sensitive, specific polymorphism discovery in bacteria using massively parallel sequencing.Nusbaum, C., Ohsumi TK, Gomez J., Aquadro J., Victor TC, Warren RM, Hung DT, Birren BW, Lander E. S., and Jaffe DB Nature methods, 2009/01/01, Volume 6, Issue 1, p.67-9, (2009) Read More / View Supplemental Materials
Abstract
SNP genotyping using the Sequenom MassARRAY iPLEX platform.Gabriel, S., Ziaugra L., and Tabbaa D. Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.], 2009/01/01, Volume Chapter 2, p.Unit 2.12, (2009) Read More / View Supplemental Materials
Abstract
2008
Highly parallel identification of essential genes in cancer cells.Luo, B., Cheung HW, Subramanian A., Sharifnia T., Okamoto M., Yang X., Hinkle G., Boehm JS, Beroukhim R., Weir BA, Mermel C., Barbie DA, Awad T., Zhou X., Nguyen T., Piqani B., Li C., Golub T. R., Meyerson M., Hacohen N., et al. Proceedings of the National Academy of Sciences of the United States of America, 2008/12/23, Volume 105, Issue 51, p.20380-5, (2008) Read More / View Supplemental Materials
Abstract
Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis.Shao, H., Burrage LC, Sinasac DS, Hill AE, Ernest SR, O'Brien W., Courtland HW, Jepsen KJ, Kirby A., Kulbokas E. J., Daly M. J., Broman KW, Lander E. S., and Nadeau JH Proceedings of the National Academy of Sciences of the United States of America, 2008/12/16, Volume 105, Issue 50, p.19910-4, (2008) Read More / View Supplemental Materials
Abstract
Synthesis of spiro-1,2-dioxolanes and their activity against Plasmodium falciparum.Martyn, DC, Ramirez AP, Beattie MJ, Cortese JF, Patel V., Rush MA, Woerpel KA, and Clardy J. Bioorganic & medicinal chemistry letters, 2008/12/15, Volume 18, Issue 24, p.6521-4, (2008) Read More / View Supplemental Materials
Abstract
Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients.Kuntzen, T., Timm J., Berical A., Lennon N., Berlin AM, Young SK, Lee B., Heckerman D., Carlson J., Reyor LL, Kleyman M., McMahon CM, Birch C., Schulze Zur Wiesch J., Ledlie T., Koehrsen M., Kodira C., Roberts AD, Lauer GM, Rosen HR, et al. Hepatology (Baltimore, Md.), 2008/12/01, Volume 48, Issue 6, p.1769-78, (2008) Read More / View Supplemental Materials
Abstract
Nodal signaling promotes the speed and directional movement of cardiomyocytes in zebrafish.de Campos-Baptista, MI, Holtzman NG, Yelon D., and Schier AF Developmental dynamics : an official publication of the American Association of Anatomists, 2008/12/01, Volume 237, Issue 12, p.3624-33, (2008) Read More / View Supplemental Materials
Abstract
Sequencing the nuclear genome of the extinct woolly mammoth.Miller, W., Drautz DI, Ratan A., Pusey B., Qi J., Lesk AM, Tomsho LP, Packard MD, Zhao F., Sher A., Tikhonov A., Raney B., Patterson N., Lindblad-Toh K., Lander E. S., Knight JR, Irzyk GP, Fredrikson KM, Harkins TT, Sheridan S., et al. Nature, 2008/11/20, Volume 456, Issue 7220, p.387-90, (2008) Read More / View Supplemental Materials
Abstract
CellProfiler Analyst: data exploration and analysis software for complex image-based screens.Jones, TR, Kang IH, Wheeler DB, Lindquist RA, Papallo A., Sabatini DM, Golland P., and Carpenter AE BMC bioinformatics, 2008/11/15, Volume 9, p.482, (2008) Read More / View Supplemental Materials
Abstract
Genetic mapping in human disease.Altshuler, D., Daly M. J., and Lander E. S. Science (New York, N.Y.), 2008/11/07, Volume 322, Issue 5903, p.881-8, (2008) Read More / View Supplemental Materials
Abstract
Gene expression in fixed tissues and outcome in hepatocellular carcinoma.Hoshida, Y., Villanueva A., Kobayashi M., Peix J., Chiang DY, Camargo A., Gupta S., Moore J., Wrobel MJ, Lerner J., Reich M., Chan JA, Glickman JN, Ikeda K., Hashimoto M., Watanabe G., Daidone MG, Roayaie S., Schwartz M., Thung S., et al. The New England journal of medicine, 2008/11/06, Volume 359, Issue 19, p.1995-2004, (2008) Read More / View Supplemental Materials
Abstract
Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines.Choy, E., Yelensky R., Bonakdar S., Plenge RM, Saxena R., De Jager PL, Shaw SY, Wolfish CS, Slavik JM, Cotsapas C., Rivas M., Dermitzakis ET, Cahir-McFarland E., Kieff E., Hafler D., Daly M. J., and Altshuler D. PLoS genetics, 2008/11/01, Volume 4, Issue 11, p.e1000287, (2008) Read More / View Supplemental Materials
Abstract
PCA and clustering reveal alternate mtDNA phylogeny of N and M clades.Alexe, G., Satya RV, Seiler M., Platt D., Bhanot T., Hui S., Tanaka M., Levine AJ, and Bhanot G. Journal of molecular evolution, 2008/11/01, Volume 67, Issue 5, p.465-87, (2008) Read More / View Supplemental Materials
Abstract
Protein quantitation through targeted mass spectrometry: the way out of biomarker purgatory?Carr, SA, and Anderson L. Clinical chemistry, 2008/11/01, Volume 54, Issue 11, p.1749-52, (2008) Read More / View Supplemental Materials
A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking.Daniels, R., Volkman SK, Milner DA, Mahesh N., Neafsey DE, Park DJ, Rosen D., Angelino E., Sabeti PC, Wirth DF, and Wiegand RC Malaria journal, 2008/10/29, Volume 7, p.223, (2008) Read More / View Supplemental Materials
Abstract
Somatic mutations affect key pathways in lung adenocarcinoma.Ding, L., Getz G., Wheeler DA, Mardis ER, McLellan MD, Cibulskis K., Sougnez C., Greulich H., Muzny DM, Morgan MB, Fulton L., Fulton RS, Zhang Q., Wendl MC, Lawrence MS, Larson DE, Chen K., Dooling DJ, Sabo A., Hawes AC, et al. Nature, 2008/10/23, Volume 455, Issue 7216, p.1069-75, (2008) Read More / View Supplemental Materials
Abstract
Activating mutations in ALK provide a therapeutic target in neuroblastoma.George, RE, Sanda T., Hanna M., Fröhling S., Luther W 2nd, Zhang J., Ahn Y., Zhou W., London WB, McGrady P., Xue L., Zozulya S., Gregor VE, Webb TR, Gray NS, Gilliland DG, Diller L., Greulich H., Morris SW, Meyerson M., et al. Nature, 2008/10/16, Volume 455, Issue 7215, p.975-8, (2008) Read More / View Supplemental Materials
Abstract
Autoimmune diseases: insights from genome-wide association studies.Lettre, G., and Rioux JD Human molecular genetics, 2008/10/15, Volume 17, Issue R2, p.R116-21, (2008) Read More / View Supplemental Materials
Abstract
Extending genome-wide association studies to copy-number variation.McCarroll, SA Human molecular genetics, 2008/10/15, Volume 17, Issue R2, p.R135-42, (2008) Read More / View Supplemental Materials
Abstract
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.Li, Z., Lu J., Sun M., Mi S., Zhang H., Luo RT, Chen P., Wang Y., Yan M., Qian Z., Neilly MB, Jin J., Zhang Y., Bohlander SK, Zhang DE, Larson RA, Le Beau MM, Thirman MJ, Golub T. R., Rowley JD, et al. Proceedings of the National Academy of Sciences of the United States of America, 2008/10/07, Volume 105, Issue 40, p.15535-40, (2008) Read More / View Supplemental Materials
Abstract
Accurate inclusion mass screening: a bridge from unbiased discovery to targeted assay development for biomarker verification.Jaffe, JD, Keshishian H., Chang B., Addona TA, Gillette MA, and Carr SA Molecular & cellular proteomics : MCP, 2008/10/01, Volume 7, Issue 10, p.1952-62, (2008) Read More / View Supplemental Materials
Abstract
Common variants at CD40 and other loci confer risk of rheumatoid arthritis.Raychaudhuri, S., Remmers EF, Lee AT, Hackett R., Guiducci C., Burtt NP, Gianniny L., Korman BD, Padyukov L., Kurreeman FA, Chang M., Catanese JJ, Ding B., Wong S., van der Helm-van Mil AH, Neale BM, Coblyn J., Cui J., Tak PP, Wolbink GJ, et al. Nature genetics, 2008/10/01, Volume 40, Issue 10, p.1216-23, (2008) Read More / View Supplemental Materials
Abstract
Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains.Ku, M., Koche RP, Rheinbay E., Mendenhall EM, Endoh M., Mikkelsen TS, Presser A., Nusbaum C., Xie X., Chi AS, Adli M., Kasif S., Ptaszek LM, Cowan CA, Lander E. S., Koseki H., and Bernstein BE PLoS genetics, 2008/10/01, Volume 4, Issue 10, p.e1000242, (2008) Read More / View Supplemental Materials
Abstract
HapMap and mapping genes for cardiovascular disease.Musunuru, K., and Kathiresan S. Circulation. Cardiovascular genetics, 2008/10/01, Volume 1, Issue 1, p.66-71, (2008) Read More / View Supplemental Materials
Abstract
High-throughput screens for fluorescent dye discovery.Ljosa, V., and Carpenter AE Trends in biotechnology, 2008/10/01, Volume 26, Issue 10, p.527-30, (2008) Read More / View Supplemental Materials
Abstract
In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis.Caron, SJ, Prober D., Choy M., and Schier AF Development (Cambridge, England), 2008/10/01, Volume 135, Issue 19, p.3259-69, (2008) Read More / View Supplemental Materials
Abstract
Integrated detection and population-genetic analysis of SNPs and copy number variation.McCarroll, SA, Kuruvilla FG, Korn JM, Cawley S., Nemesh J., Wysoker A., Shapero MH, de Bakker PI, Maller JB, Kirby A., Elliott AL, Parkin M., Hubbell E., Webster T., Mei R., Veitch J., Collins PJ, Handsaker R., Lincoln S., Nizzari M., et al. Nature genetics, 2008/10/01, Volume 40, Issue 10, p.1166-74, (2008) Read More / View Supplemental Materials
Abstract
Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs.Korn, JM, Kuruvilla FG, McCarroll SA, Wysoker A., Nemesh J., Cawley S., Hubbell E., Veitch J., Collins PJ, Darvishi K., Lee C., Nizzari MM, Gabriel SB, Purcell S., Daly M. J., and Altshuler D. Nature genetics, 2008/10/01, Volume 40, Issue 10, p.1253-60, (2008) Read More / View Supplemental Materials
Abstract
Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury.Lewis, GD, Wei R., Liu E., Yang E., Shi X., Martinovic M., Farrell L., Asnani A., Cyrille M., Ramanathan A., Shaham O., Berriz G., Lowry PA, Palacios IF, Taşan M., Roth FP, Min J., Baumgartner C., Keshishian H., Addona T., et al. The Journal of clinical investigation, 2008/10/01, Volume 118, Issue 10, p.3503-12, (2008) Read More / View Supplemental Materials
Abstract
A common sequence motif associated with recombination hot spots and genome instability in humans.Myers, S., Freeman C., Auton A., Donnelly P., and McVean G. Nature genetics, 2008/09/01, Volume 40, Issue 9, p.1124-9, (2008) Read More / View Supplemental Materials
Abstract
Evolutionary toggling of the MAPT 17q21.31 inversion region.Zody, MC, Jiang Z., Fung HC, Antonacci F., Hillier LW, Cardone MF, Graves TA, Kidd JM, Cheng Z., Abouelleil A., Chen L., Wallis J., Glasscock J., Wilson RK, Reily AD, Duckworth J., Ventura M., Hardy J., Warren WC, and Eichler EE Nature genetics, 2008/09/01, Volume 40, Issue 9, p.1076-83, (2008) Read More / View Supplemental Materials
Abstract
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.Graham, RR, Cotsapas C., Davies L., Hackett R., Lessard CJ, Leon JM, Burtt NP, Guiducci C., Parkin M., Gates C., Plenge RM, Behrens TW, Wither JE, Rioux JD, Fortin PR, Graham DC, Wong AK, Vyse TJ, Daly M. J., Altshuler D., et al. Nature genetics, 2008/09/01, Volume 40, Issue 9, p.1059-61, (2008) Read More / View Supplemental Materials
Abstract
Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells.Tam, WF, Gu TL, Chen J., Lee BH, Bullinger L., Fröhling S., Wang A., Monti S., Golub T. R., and Gilliland DG Blood, 2008/09/01, Volume 112, Issue 5, p.1981-92, (2008) Read More / View Supplemental Materials
Abstract
Leader of the pack: gene mapping in dogs and other model organisms.Karlsson, EK, and Lindblad-Toh K. Nature reviews. Genetics, 2008/09/01, Volume 9, Issue 9, p.713-25, (2008) Read More / View Supplemental Materials
Abstract
Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor.Bowers, A., West N., Taunton J., Schreiber SL, Bradner JE, and Williams RM Journal of the American Chemical Society, 2008/08/20, Volume 130, Issue 33, p.11219-22, (2008) Read More / View Supplemental Materials
Abstract
DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease.Lettre, G., Sankaran VG, Bezerra MA, Araújo AS, Uda M., Sanna S., Cao A., Schlessinger D., Costa FF, Hirschhorn JN, and Orkin SH Proceedings of the National Academy of Sciences of the United States of America, 2008/08/19, Volume 105, Issue 33, p.11869-74, (2008) Read More / View Supplemental Materials
Abstract
Genome-scale DNA methylation maps of pluripotent and differentiated cells.Meissner, A., Mikkelsen TS, Gu H., Wernig M., Hanna J., Sivachenko A., Zhang X., Bernstein BE, Nusbaum C., Jaffe DB, Gnirke A., Jaenisch R., and Lander E. S. Nature, 2008/08/07, Volume 454, Issue 7205, p.766-70, (2008) Read More / View Supplemental Materials
Abstract
Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells.Haining, WN, Ebert BL, Subrmanian A., Wherry EJ, Eichbaum Q., Evans JW, Mak R., Rivoli S., Pretz J., Angelosanto J., Smutko JS, Walker BD, Kaech SM, Ahmed R., Nadler LM, and Golub T. R. Journal of immunology (Baltimore, Md. : 1950), 2008/08/01, Volume 181, Issue 3, p.1859-68, (2008) Read More / View Supplemental Materials
Abstract
A set of reference sequences for the hepatitis C genotypes 4d, 4f, and 4k covering the full open reading frame.Kuntzen, T., Berical A., Ndjomou J., Bennett P., Schneidewind A., Lennon N., Birren BW, Kuiken C., Henn MR, Simmonds P., and Allen TM Journal of medical virology, 2008/08/01, Volume 80, Issue 8, p.1370-8, (2008) Read More / View Supplemental Materials
Abstract
Conserved secondary structures in Aspergillus.McGuire, AM, and Galagan JE PloS one, 2008/07/30, Volume 3, Issue 7, p.e2812, (2008) Read More / View Supplemental Materials
Abstract
Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiationHahn, Cynthia K., Ross Kenneth N., Warrington Ian M., Mazitschek Ralph, Kanegai Cindy M., Wright Renee D., Kung Andrew L., Golub Todd R., and Stegmaier Kimberly Proceedings of the National Academy of Sciences of the United States of America, 2008/07/15/, Volume 105, Issue 28, p.9751 - 6, (2008) Read More / View Supplemental Materials
Abstract
Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation.Hahn, CK, Ross KN, Warrington IM, Mazitschek R., Kanegai CM, Wright RD, Kung AL, Golub T. R., and Stegmaier K. Proceedings of the National Academy of Sciences of the United States of America, 2008/07/15, Volume 105, Issue 28, p.9751-6, (2008) Read More / View Supplemental Materials
Abstract
A mitochondrial protein compendium elucidates complex I disease biologyPagliarini, David J., Calvo Sarah E., Chang Betty, Sheth Sunil A., Vafai Scott B., Ong Shao-En, Walford Geoffrey A., Sugiana Canny, Boneh Avihu, Chen William K., Hill David E., Vidal Marc, Evans James G., Thorburn David R., Carr Steven A., and Mootha Vamsi K. Cell, 2008/07/11/, Volume 134, Issue 1, p.112 - 23, (2008) Read More / View Supplemental Materials
Abstract
A mitochondrial protein compendium elucidates complex I disease biology.Pagliarini, DJ, Calvo SE, Chang B., Sheth SA, Vafai SB, Ong SE, Walford GA, Sugiana C., Boneh A., Chen WK, Hill DE, Vidal M., Evans JG, Thorburn DR, Carr SA, and Mootha VK Cell, 2008/07/11, Volume 134, Issue 1, p.112-23, (2008) Read More / View Supplemental Materials
Abstract
Dissecting direct reprogramming through integrative genomic analysis.Mikkelsen, TS, Hanna J., Zhang X., Ku M., Wernig M., Schorderet P., Bernstein BE, Jaenisch R., Lander E. S., and Meissner A. Nature, 2008/07/03, Volume 454, Issue 7200, p.49-55, (2008) Read More / View Supplemental Materials
Abstract
Diversity synthesis of complex pyridines yields a probe of a neurotrophic signaling pathway.Gray, BL, Wang X., Brown WC, Kuai L., and Schreiber SL Organic letters, 2008/07/03, Volume 10, Issue 13, p.2621-4, (2008) Read More / View Supplemental Materials
Abstract
15-Hydroxyprostaglandin dehydrogenase is a target of hepatocyte nuclear factor 3beta and a tumor suppressor in lung cancerHuang, Guosheng, Eisenberg Rosana, Yan Min, Monti Stefano, Lawrence Earl, Fu Pingfu, Walbroehl Jaclyn, and L Cancer Research, 2008/07/01/, Volume 68, Issue 13, p.5040 - 8, (2008) Read More / View Supplemental Materials
Abstract
Increasing ecological inference from high throughput sequencing of fungi in the environment through a tagging approach.Taylor, DL, Booth MG, McFarland JW, Herriott IC, Lennon NJ, Nusbaum C., and Marr TG Molecular ecology resources, 2008/07/01, Volume 8, Issue 4, p.742-52, (2008) Read More / View Supplemental Materials
Abstract
Small-molecule microarrays as tools in ligand discovery.Vegas, AJ, Fuller JH, and Koehler AN Chemical Society reviews, 2008/07/01, Volume 37, Issue 7, p.1385-94, (2008) Read More / View Supplemental Materials
Abstract
Drug-sensitive FGFR2 mutations in endometrial carcinoma.Dutt, A., Salvesen HB, Chen TH, Ramos AH, Onofrio RC, Hatton C., Nicoletti R., Winckler W., Grewal R., Hanna M., Wyhs N., Ziaugra L., Richter DJ, Trovik J., Engelsen IB, Stefansson IM, Fennell T., Cibulskis K., Zody MC, Akslen LA, et al. Proceedings of the National Academy of Sciences of the United States of America, 2008/06/24, Volume 105, Issue 25, p.8713-7, (2008) Read More / View Supplemental Materials
Abstract
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancerSetlur, Sunita R., Mertz Kirsten D., Hoshida Yujin, Demichelis Francesca, Lupien Mathieu, Perner Sven, Sboner Andrea, Pawitan Yudi, and Andr Journal of the National Cancer Institute, 2008/06/04/, Volume 100, Issue 11, p.815 - 25, (2008) Read More / View Supplemental Materials
Abstract
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer.Setlur, SR, Mertz KD, Hoshida Y., Demichelis F., Lupien M., Perner S., Sboner A., Pawitan Y., Andrén O., Johnson LA, Tang J., Adami HO, Calza S., Chinnaiyan AM, Rhodes D., Tomlins S., Fall K., Mucci LA, Kantoff PW, Stampfer MJ, et al. Journal of the National Cancer Institute, 2008/06/04, Volume 100, Issue 11, p.815-25, (2008) Read More / View Supplemental Materials
Abstract
The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.Lee, KB, De Backer P., Aono T., Liu CT, Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer DM, Najar FZ, Wiley GB, Roe B., Binnewies TT, Ussery DW, D'Haeze W., Herder JD, Gevers D., Vereecke D., Holsters M., et al. BMC genomics, 2008/06/04, Volume 9, p.271, (2008) Read More / View Supplemental Materials
Abstract
Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cellsMishra, Pravin J., Mishra Prasun J., Humeniuk Rita, Medina Daniel J., Alexe Gabriela, Mesirov Jill P., Ganesan Sridhar, Glod John W., and Banerjee Debabrata Cancer Research, 2008/06/01/, Volume 68, Issue 11, p.4331 - 9, (2008) Read More / View Supplemental Materials
Abstract
MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors.Lu, J., Guo S., Ebert BL, Zhang H., Peng X., Bosco J., Pretz J., Schlanger R., Wang JY, Mak RH, Dombkowski DM, Preffer FI, Scadden DT, and Golub T. R. Developmental cell, 2008/06/01, Volume 14, Issue 6, p.843-53, (2008) Read More / View Supplemental Materials
Abstract
Targeted mutagenesis in zebrafish.Woods, IG, and Schier AF Nature biotechnology, 2008/06/01, Volume 26, Issue 6, p.650-1, (2008) Read More / View Supplemental Materials
Transcriptome and metabolite responses to predation in a South pacific soft coral.Hoover, CA, Slattery M., Targett NM, and Marsh AG The Biological bulletin, 2008/06/01, Volume 214, Issue 3, p.319-28, (2008) Read More / View Supplemental Materials
Abstract
Using ChemBank to probe chemical biology.Petri Seiler, K., Kuehn H., Pat Happ M., DeCaprio D., and Clemons PA Current protocols in bioinformatics / editoral board, Andreas D. Baxevanis ... [et al.], 2008/06/01, Volume Chapter 14, p.Unit 14.5, (2008) Read More / View Supplemental Materials
Abstract
Using GenePattern for gene expression analysis.Kuehn, H., Liberzon A., Reich M., and Mesirov J. P. Current protocols in bioinformatics / editoral board, Andreas D. Baxevanis ... [et al.], 2008/06/01, Volume Chapter 7, p.Unit 7.12, (2008) Read More / View Supplemental Materials
Abstract
MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitorsLu, Jun, Guo Shangqin, Ebert Benjamin L., Zhang Hao, Peng Xiao, Bosco Jocelyn, Pretz Jennifer, Schlanger Rita, Wang Judy Y., Mak Raymond H., Dombkowski David M., Preffer Frederic I., Scadden David T., and Golub Todd R. Developmental Cell, 2008/06//, Volume 14, Issue 6, p.843 - 53, (2008) Read More / View Supplemental Materials
Abstract
Perturbational profiling of nanomaterial biologic activity.Shaw, SY, Westly EC, Pittet MJ, Subramanian A., Schreiber SL, and Weissleder R. Proceedings of the National Academy of Sciences of the United States of America, 2008/05/27, Volume 105, Issue 21, p.7387-92, (2008) Read More / View Supplemental Materials
Abstract
Resource partitioning and sympatric differentiation among closely related bacterioplankton.Hunt, DE, David LA, Gevers D., Preheim SP, Alm EJ, and Polz MF Science (New York, N.Y.), 2008/05/23, Volume 320, Issue 5879, p.1081-5, (2008) Read More / View Supplemental Materials
Abstract
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways.Onder, TT, Gupta PB, Mani SA, Yang J., Lander E. S., and Weinberg R. A. Cancer research, 2008/05/15, Volume 68, Issue 10, p.3645-54, (2008) Read More / View Supplemental Materials
Abstract
ALLPATHS: de novo assembly of whole-genome shotgun microreads.Butler, J., Maccallum I., Kleber M., Shlyakhter IA, Belmonte MK, Lander E. S., Nusbaum C., and Jaffe DB Genome research, 2008/05/01, Volume 18, Issue 5, p.810-20, (2008) Read More / View Supplemental Materials
Abstract
Can one learn history from the allelic spectrum?Myers, S., Fefferman C., and Patterson N. Theoretical population biology, 2008/05/01, Volume 73, Issue 3, p.342-8, (2008) Read More / View Supplemental Materials
Abstract
Development of a fluorescence polarization based assay for histone deacetylase ligand discovery.Mazitschek, R., Patel V., Wirth DF, and Clardy J. Bioorganic & medicinal chemistry letters, 2008/05/01, Volume 18, Issue 9, p.2809-12, (2008) Read More / View Supplemental Materials
Abstract
Identification of ten loci associated with height highlights new biological pathways in human growth.Lettre, G., Jackson AU, Gieger C., Schumacher FR, Berndt SI, Sanna S., Eyheramendy S., Voight BF, Butler JL, Guiducci C., Illig T., Hackett R., Heid IM, Jacobs KB, Lyssenko V., Uda M., Diabetes Genetics Initiative, FUSION, KORA, Prostate, Lung Colorectal and Ovarian Cancer Screening Trial, et al. Nature genetics, 2008/05/01, Volume 40, Issue 5, p.584-91, (2008) Read More / View Supplemental Materials
Abstract
Mapping and sequencing of structural variation from eight human genomes.Kidd, JM, Cooper GM, Donahue WF, Hayden HS, Sampas N., Graves T., Hansen N., Teague B., Alkan C., Antonacci F., Haugen E., Zerr T., Yamada NA, Tsang P., Newman TL, Tüzün E., Cheng Z., Ebling HM, Tusneem N., David R., et al. Nature, 2008/05/01, Volume 453, Issue 7191, p.56-64, (2008) Read More / View Supplemental Materials
Abstract
Quality scores and SNP detection in sequencing-by-synthesis systems.Brockman, W., Alvarez P., Young S., Garber M., Giannoukos G., Lee WL, Russ C., Lander E. S., Nusbaum C., and Jaffe DB Genome research, 2008/05/01, Volume 18, Issue 5, p.763-70, (2008) Read More / View Supplemental Materials
Abstract
Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): I. CIP Treatment of Samples and Tailing Reaction with Terminal Transferase.Liu, CL, Bernstein BE, and Schreiber SL CSH protocols, 2008/05/01, Volume 2008, p.pdb.prot5002, (2008) Read More / View Supplemental Materials
Abstract
Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): II. Second-Strand Synthesis and In Vitro Transcription.Liu, CL, Bernstein BE, and Schreiber SL CSH protocols, 2008/05/01, Volume 2008, p.pdb.prot5003, (2008) Read More / View Supplemental Materials
Abstract
Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): III. Sample Purification.Liu, CL, Bernstein BE, and Schreiber SL CSH protocols, 2008/05/01, Volume 2008, p.pdb.prot5004, (2008) Read More / View Supplemental Materials
Abstract
Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): Overview.Liu, CL, Bernstein BE, and Schreiber SL CSH protocols, 2008/05/01, Volume 2008, p.pdb.top42, (2008) Read More / View Supplemental Materials
Abstract
Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastasesXu, Lei, Shen Steven S., Hoshida Yujin, Subramanian Aravind, Ross Ken, Brunet Jean-Philippe, Wagner Stephan N., Ramaswamy Sridhar, Mesirov Jill P., and Hynes Richard O. Molecular Cancer Research: MCR, 2008/05//, Volume 6, Issue 5, p.760 - 9, (2008) Read More / View Supplemental Materials
Abstract
Performance and scalability of discriminative metrics for comparative gene identification in 12 Drosophila genomes.Lin, MF, Deoras AN, Rasmussen MD, and Kellis M. PLoS computational biology, 2008/04/18, Volume 4, Issue 4, p.e1000067, (2008) Read More / View Supplemental Materials
Abstract