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2012
ChromHMM: automating chromatin-state discovery and characterization.Ernst, J., and Kellis M. Nature methods, 2012/02/28, Volume 9, Issue 3, p.215-6, (2012) Read More / View Supplemental Materials
Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay.Melnikov, A., Murugan A., Zhang X., Tesileanu T., Wang L., Rogov P., Feizi S., Gnirke A., Callan CG Jr, Kinney JB, Kellis M., Lander E. S., and Mikkelsen TS Nature biotechnology, 2012/02/26, Volume 30, Issue 3, p.271-7, (2012) Read More / View Supplemental Materials
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Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011.Grad, YH, Lipsitch M., Feldgarden M., Arachchi HM, Cerqueira GC, FitzGerald M., Godfrey P., Haas BJ, Murphy CI, Russ C., Sykes S., Walker BJ, Wortman JR, Young S., Zeng Q., Abouelleil A., Bochicchio J., Chauvin S., Desmet T., Gujja S., et al. Proceedings of the National Academy of Sciences of the United States of America, 2012/02/21, Volume 109, Issue 8, p.3065-70, (2012) Read More / View Supplemental Materials
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STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability.Luo, T., Masson K., Jaffe JD, Silkworth W., Ross NT, Scherer CA, Scholl C., Fröhling S., Carr SA, Stern AM, Schreiber SL, and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2012/02/21, Volume 109, Issue 8, p.2860-5, (2012) Read More / View Supplemental Materials
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Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture.Rohland, N., and Reich D. Genome research, 2012/02/16, (2012) Read More / View Supplemental Materials
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A PIP Gets the Plasmodium Protein Export Pathway Going.Jiang, RH, and Marti M. Cell host & microbe, 2012/02/16, Volume 11, Issue 2, p.99-100, (2012) Read More / View Supplemental Materials
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Unified modeling of gene duplication, loss, and coalescence using a locus tree.Rasmussen, MD, and Kellis M. Genome research, 2012/02/16, (2012) Read More / View Supplemental Materials
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Development of small-molecule probes that selectively kill cells induced to express mutant RAS.Weïwer, M., Bittker JA, Lewis TA, Shimada K., Yang WS, Macpherson L., Dandapani S., Palmer M., Stockwell BR, Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2012/02/15, Volume 22, Issue 4, p.1822-6, (2012) Read More / View Supplemental Materials
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Modular regulatory principles of large non-coding RNAs.Guttman, M., and Rinn JL Nature, 2012/02/15, Volume 482, Issue 7385, p.339-46, (2012) Read More / View Supplemental Materials
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Genome-wide siRNA screen for mediators of NF-κB activation.Gewurz, BE, Towfic F., Mar JC, Shinners NP, Takasaki K., Zhao B., Cahir-McFarland ED, Quackenbush J., Xavier RJ, and Kieff E. Proceedings of the National Academy of Sciences of the United States of America, 2012/02/14, Volume 109, Issue 7, p.2467-72, (2012) Read More / View Supplemental Materials
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Build/Couple/Pair Strategy for the Synthesis of Stereochemically Diverse Macrolactams via Head-to-Tail Cyclization.Fitzgerald, ME, Mulrooney CA, Duvall JR, Wei J., Suh BC, Akella LB, Vrcic A., and Marcaurelle LA ACS combinatorial science, 2012/02/13, Volume 14, Issue 2, p.89-96, (2012) Read More / View Supplemental Materials
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Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria.Heidebrecht RW, Jr, Mulrooney C., Austin CP, Barker RH Jr, Beaudoin JA, Cheng KC, Comer E., Dandapani S., Dick J., Duvall JR, Ekland EH, Fidock DA, Fitzgerald ME, Foley M., Guha R., Hinkson P., Kramer M., Lukens AK, Masi D., Marcaurelle LA, et al. ACS medicinal chemistry letters, 2012/02/09, Volume 3, Issue 2, p.112-117, (2012) Read More / View Supplemental Materials
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Treatment of the respiratory distress syndrome in newborns: smoothened agonist counterbalances deleterious effects of glucocorticoids .Griveau, A. Medecine sciences : M/S, 2012/02/01, Volume 28, Issue 2, p.141-3, (2012) Read More / View Supplemental Materials
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis.Raychaudhuri, S., Sandor C., Stahl EA, Freudenberg J., Lee HS, Jia X., Alfredsson L., Padyukov L., Klareskog L., Worthington J., Siminovitch KA, Bae SC, Plenge RM, Gregersen PK, and de Bakker PI Nature genetics, 2012/01/29, Volume 44, Issue 3, p.291-6, (2012) Read More / View Supplemental Materials
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RNA folding with soft constraints: reconciliation of probing data and thermodynamic secondary structure prediction.Washietl, S., Hofacker IL, Stadler PF, and Kellis M. Nucleic acids research, 2012/01/28, (2012) Read More / View Supplemental Materials
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The numerology of T cell functional diversity.Haining, WN Immunity, 2012/01/27, Volume 36, Issue 1, p.10-2, (2012) Read More / View Supplemental Materials
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The mystery of missing heritability: Genetic interactions create phantom heritability.Zuk, O., Hechter E., Sunyaev SR, and Lander E. S. Proceedings of the National Academy of Sciences of the United States of America, 2012/01/24, Volume 109, Issue 4, p.1193-8, (2012) Read More / View Supplemental Materials
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Human evolutionary genomics: ethical and interpretive issues.Vitti, JJ, Cho MK, Tishkoff SA, and Sabeti PC Trends in genetics : TIG, 2012/01/20, (2012) Read More / View Supplemental Materials
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Genetic variation at CR1 increases risk of cerebral amyloid angiopathy.Biffi, A., Shulman JM, Jagiella JM, Cortellini L., Ayres AM, Schwab K., Brown DL, Silliman SL, Selim M., Worrall BB, Meschia JF, Slowik A., De Jager PL, Greenberg SM, Schneider JA, Bennett DA, and Rosand J. Neurology, 2012/01/18, (2012) Read More / View Supplemental Materials
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Analyzing and minimizing PCR amplification bias in Illumina sequencing libraries.Aird, D., Ross MG, Chen WS, Danielsson M., Fennell T., Russ C., Jaffe DB, Nusbaum C., and Gnirke A. Genome biology, 2012/01/09, Volume 12, Issue 2, p.R18, (2012) Read More / View Supplemental Materials
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Assisted assembly: how to improve a de novo genome assembly by using related species.Gnerre, S., Lander E. S., Lindblad-Toh K., and Jaffe DB Genome biology, 2012/01/09, Volume 10, Issue 8, p.R88, (2012) Read More / View Supplemental Materials
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Chemical Genetic Analysis of Platelet Granule Secretion-Probe 1VerPlank, L., Dockendorff C., Negri J., Perez JR, Dilks J., Macpherson L., Palmer M., Flaumenhaft R., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
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Chemical Genetic Analysis of Platelet Granule Secretion-Probe 2VerPlank, L., Dockendorff C., Negri J., Perez JR, Dilks J., Macpherson L., Palmer M., Flaumenhaft R., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
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Chemical Genetic Analysis of Platelet Granule Secretion-Probe 3VerPlank, L., Dockendorff C., Negri J., Perez JR, Dilks J., Macpherson L., Palmer M., Flaumenhaft R., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
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Exploiting nucleotide composition to engineer promoters.Grabherr, MG, Pontiller J., Mauceli E., Ernst W., Baumann M., Biagi T., Swofford R., Russell P., Zody MC, Di Palma F., Lindblad-Toh K., and Grabherr RM PloS one, 2012/01/09, Volume 6, Issue 5, p.e20136, (2012) Read More / View Supplemental Materials
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Extracting rich information from images.Carpenter, AE Methods in molecular biology (Clifton, N.J.), 2012/01/09, Volume 486, p.193-211, (2012) Read More / View Supplemental Materials
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The fungal genome initiative and lessons learned from genome sequencing.Cuomo, CA, and Birren BW Methods in enzymology, 2012/01/09, Volume 470, p.833-55, (2012) Read More / View Supplemental Materials
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GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers.Mermel, CH, Schumacher SE, Hill B., Meyerson ML, Beroukhim R., and Getz G. Genome biology, 2012/01/09, Volume 12, Issue 4, p.R41, (2012) Read More / View Supplemental Materials
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High-throughput real-time PCR for detection of gene-expression levels.Wagner, BK, and Arany Z. Methods in molecular biology (Clifton, N.J.), 2012/01/09, Volume 486, p.167-75, (2012) Read More / View Supplemental Materials
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Identification of a small molecule that selectively activates alpha-synuclein translational expressionRoss, NT, Metkar SR, Le H., Burbank J., Cahill C., Germain A., Macpherson L., Bittker J., Palmer M., Rogers J., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
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Identification of a small molecule that selectively inhibits alpha-synuclein translational expressionRoss, NT, Metkar SR, Le H., Burbank J., Cahill C., Germain A., Macpherson L., Bittker J., Palmer M., Rogers J., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
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Identification of Small Molecule Inhibitors that Suppress Cytokine-Induced Apoptosis in Human Pancreatic Islet CellsFaloon, PW, Chou DHC, Forbeck EM, Walpita D., Morgan B., Buhrlage S., Ting A., Perez J., MacPherson LJ, Duvall JR, Dandapani S., Marcaurelle LA, Munoz B., Palmer M., Foley M., Wagner B., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
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Identification of small molecules that selectively inhibit streptokinase expression without suppression of viability in Group A streptococci - Probe 1An, WF, Metkar SR, Nag PP, Hartland CL, Barker D., Perez JR, Sun H., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
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Identification of small molecules that selectively inhibit streptokinase expression without suppression of viability in Group A streptococci - Probe 2An, WF, Metkar SR, Lewis TA, Nag PP, Hartland CL, Barker D., Perez JR, Sun H., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
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Identification of small molecules that selectively inhibit streptokinase expression without suppression of viability in Group A streptococci - Probe 3An, WF, Metkar SR, Youngsaye W., Nag PP, Hartland CL, Barker D., Perez JR, Sun H., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
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Identification of Small-Molecule Inhibitors of Trypansoma cruzi InfectionCarmody, LC, Germain A., Barker D., Galan-Rodriguez C., Bettiol E., Rodriguez A., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
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Identification of Small-Molecule Inhibitors of Trypansoma cruzi Infection - Probe 1Carmody, LC, Germain A., Barker D., Galan-Rodriguez C., Bettiol E., Rodriguez A., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
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Identification of Small-Molecule Inhibitors of Trypansoma cruzi Infection - Probe 3Carmody, LC, Germain A., Barker D., Galan-Rodriguez C., Bettiol E., Rodriguez A., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
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Identifying cellular targets of small-molecule probes and drugs with biochemical enrichment and SILAC.Ong, SE, Li X., Schenone M., Schreiber SL, and Carr SA Methods in molecular biology (Clifton, N.J.), 2012/01/09, Volume 803, p.129-40, (2012) Read More / View Supplemental Materials
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Introduction: cell-based assays for high-throughput screening.An, WF, and Tolliday NJ Methods in molecular biology (Clifton, N.J.), 2012/01/09, Volume 486, p.1-12, (2012) Read More / View Supplemental Materials
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Large-scale identification of genetic design strategies using local search.Lun, DS, Rockwell G., Guido NJ, Baym M., Kelner JA, Berger B., Galagan JE, and Church GM Molecular systems biology, 2012/01/09, Volume 5, p.296, (2012) Read More / View Supplemental Materials
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Layout.Wong, B. Nature methods, 2012/01/09, Volume 8, Issue 10, p.783, (2012) Read More / View Supplemental Materials
Ligand discovery using small-molecule microarrays.Casalena, DE, Wassaf D., and Koehler AN Methods in molecular biology (Clifton, N.J.), 2012/01/09, Volume 803, p.249-63, (2012) Read More / View Supplemental Materials
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'Next-generation' sequencing becomes 'now-generation'.Neafsey, DE, and Haas BJ Genome biology, 2012/01/09, Volume 12, Issue 3, p.303, (2012) Read More / View Supplemental Materials
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The NIH's role in accelerating translational sciences.Reed, JC, White EL, Aubé J., Lindsley C., Li M., Sklar L., and Schreiber S. Nature biotechnology, 2012/01/09, Volume 30, Issue 1, p.16-9, (2012) Read More / View Supplemental Materials
A scalable, fully automated process for construction of sequence-ready human exome targeted capture libraries.Fisher, S., Barry A., Abreu J., Minie B., Nolan J., Delorey TM, Young G., Fennell TJ, Allen A., Ambrogio L., Berlin AM, Blumenstiel B., Cibulskis K., Friedrich D., Johnson R., Juhn F., Reilly B., Shammas R., Stalker J., Sykes SM, et al. Genome biology, 2012/01/09, Volume 12, Issue 1, p.R1, (2012) Read More / View Supplemental Materials
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Sequences to systems.Kellis, M., and Rinn JL Genome biology, 2012/01/09, Volume 11, Issue 5, p.303, (2012) Read More / View Supplemental Materials
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Strand-specific RNA sequencing reveals extensive regulated long antisense transcripts that are conserved across yeast species.Yassour, M., Pfiffner J., Levin JZ, Adiconis X., Gnirke A., Nusbaum C., Thompson DA, Friedman N., and Regev A. Genome biology, 2012/01/09, Volume 11, Issue 8, p.R87, (2012) Read More / View Supplemental Materials
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Targeted next-generation sequencing of a cancer transcriptome enhances detection of sequence variants and novel fusion transcripts.Levin, JZ, Berger MF, Adiconis X., Rogov P., Melnikov A., Fennell T., Nusbaum C., Garraway LA, and Gnirke A. Genome biology, 2012/01/09, Volume 10, Issue 10, p.R115, (2012) Read More / View Supplemental Materials
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Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence.Neafsey, DE, Schaffner SF, Volkman SK, Park D., Montgomery P., Milner DA Jr, Lukens A., Rosen D., Daniels R., Houde N., Cortese JF, Tyndall E., Gates C., Stange-Thomann N., Sarr O., Ndiaye D., Ndir O., Mboup S., Ferreira MU, Moraes Sdo L., et al. Genome biology, 2012/01/07, Volume 9, Issue 12, p.R171, (2012) Read More / View Supplemental Materials
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Complex alpha-pyrones synthesized by a gold-catalyzed coupling reaction.Luo, T., and Schreiber SL Angewandte Chemie (International ed. in English), 2012/01/06, Volume 46, Issue 43, p.8250-3, (2012) Read More / View Supplemental Materials
Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts.D'Souza, CA, Kronstad JW, Taylor G., Warren R., Yuen M., Hu G., Jung WH, Sham A., Kidd SE, Tangen K., Lee N., Zeilmaker T., Sawkins J., McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W., et al. mBio, 2012/01/06, Volume 2, Issue 1, p.e00342-10, (2012) Read More / View Supplemental Materials
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A microarray-based protocol for monitoring the growth of yeast overexpression strains.Butcher, RA, and Schreiber SL Nature protocols, 2012/01/06, Volume 1, Issue 2, p.569-76, (2012) Read More / View Supplemental Materials
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Multilevel regulation of growth rate in yeast revealed using systems biology.Ramanathan, A., and Schreiber SL Journal of biology, 2012/01/06, Volume 6, Issue 2, p.3, (2012) Read More / View Supplemental Materials
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A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC).Ong, SE, and Mann M. Nature protocols, 2012/01/06, Volume 1, Issue 6, p.2650-60, (2012) Read More / View Supplemental Materials
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Stable isotope labeling by amino acids in cell culture for quantitative proteomics.Ong, SE, and Mann M. Methods in molecular biology (Clifton, N.J.), 2012/01/06, Volume 359, p.37-52, (2012) Read More / View Supplemental Materials
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Application of natural product-inspired diversity-oriented synthesis to drug discovery.Marcaurelle, LA, and Johannes CW Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 2012/01/05, Volume 66, p.187, 189-216, (2012) Read More / View Supplemental Materials
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Cross-kingdom patterns of alternative splicing and splice recognition.McGuire, AM, Pearson MD, Neafsey DE, and Galagan JE Genome biology, 2012/01/05, Volume 9, Issue 3, p.R50, (2012) Read More / View Supplemental Materials
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Gene expression-based screening for inhibitors of PDGFR signaling.Antipova, AA, Stockwell BR, and Golub T. R. Genome biology, 2012/01/05, Volume 9, Issue 3, p.R47, (2012) Read More / View Supplemental Materials
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A transcription activator-like effector toolbox for genome engineering.Sanjana, NE, Cong L., Zhou Y., Cunniff MM, Feng G., and Zhang F. Nature protocols, 2012/01/05, Volume 7, Issue 1, p.171-92, (2012) Read More / View Supplemental Materials
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Autophagy and the immune system.Kuballa, P., Nolte WM, Castoreno AB, and Xavier RJ Annual review of immunology, 2012/01/01, Volume 30, p.611-46, (2012) Read More / View Supplemental Materials
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Bioinformatic Discovery of Bacterial Regulatory RNAs Using SIPHT.Livny, J. Methods in molecular biology (Clifton, N.J.), 2012/01/01, Volume 905, p.3-14, (2012) Read More / View Supplemental Materials
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Characterization and Robust Classification of EEG Signal from Image RSVP Events with Independent Time-Frequency Features.Meng, J., Meriño LM, Shamlo NB, Makeig S., Robbins K., and Huang Y. PloS one, 2012/01/01, Volume 7, Issue 9, p.e44464, (2012) Read More / View Supplemental Materials
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Chemical Methods to Induce Beta-Cell Proliferation.Vetere, A., and Wagner BK International journal of endocrinology, 2012/01/01, Volume 2012, p.925143, (2012) Read More / View Supplemental Materials
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A Chemical Screen Probing the Relationship between Mitochondrial Content and Cell Size.Kitami, T., Logan DJ, Negri J., Hasaka T., Tolliday NJ, Carpenter AE, Spiegelman BM, and Mootha VK PloS one, 2012/01/01, Volume 7, Issue 3, p.e33755, (2012) Read More / View Supplemental Materials
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Comparative Genome Analysis of Trichophyton rubrum and Related Dermatophytes Reveals Candidate Genes Involved in Infection.Martinez, DA, Oliver BG, Gräser Y., Goldberg JM, Li W., Martinez-Rossi NM, Monod M., Shelest E., Barton RC, Birch E., Brakhage AA, Chen Z., Gurr SJ, Heiman D., Heitman J., Kosti I., Rossi A., Saif S., Samalova M., Saunders CW, et al. mBio, 2012/01/01, Volume 3, Issue 5, (2012) Read More / View Supplemental Materials
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Correction: GW8510 Increases Insulin Expression in Pancreatic Alpha Cells through Activation of p53 Transcriptional Activity.Fomina-Yadlin, D., Kubicek S., Vetere A., Hu He KH, Schreiber SL, and Wagner BK PloS one, 2012/01/01, Volume 7, Issue 3, (2012) Read More / View Supplemental Materials
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Effects of genetic variants previously associated with fasting glucose and insulin in the diabetes prevention program.Florez, JC, Jablonski KA, McAteer JB, Franks PW, Mason CC, Mather K., Horton E., Goldberg R., Dabelea D., Kahn SE, Arakaki RF, Shuldiner AR, Knowler WC, and Diabetes Prevention Program Research Group PloS one, 2012/01/01, Volume 7, Issue 9, p.e44424, (2012) Read More / View Supplemental Materials
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GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity.Fomina-Yadlin, D., Kubicek S., Vetere A., He KH, Schreiber SL, and Wagner BK PloS one, 2012/01/01, Volume 7, Issue 1, p.e28808, (2012) Read More / View Supplemental Materials
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HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants.Ward, LD, and Kellis M. Nucleic acids research, 2012/01/01, Volume 40, Issue 1, p.D930-4, (2012) Read More / View Supplemental Materials
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High-resolution analysis of intrahost genetic diversity in dengue virus serotype 1 infection identifies mixed infections.Thai, KT, Henn MR, Zody MC, Tricou V., Nguyet NM, Charlebois P., Lennon NJ, Green L., de Vries PJ, Hien TT, Farrar J., van Doorn HR, de Jong MD, Birren BW, Holmes EC, and Simmons CP Journal of virology, 2012/01/01, Volume 86, Issue 2, p.835-43, (2012) Read More / View Supplemental Materials
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High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing.Wagle, N., Berger MF, Davis MJ, Blumenstiel B., DeFelice M., Pochanard P., Ducar M., Van Hummelen P., Macconaill LE, Hahn WC, Meyerson M., Gabriel SB, and Garraway LA Cancer discovery, 2012/01/01, Volume 2, Issue 1, p.82-93, (2012) Read More / View Supplemental Materials
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Independent Large Scale Duplications in Multiple M. tuberculosis Lineages Overlapping the Same Genomic Region.Weiner, B., Gomez J., Victor TC, Warren RM, Sloutsky A., Plikaytis BB, Posey JE, van Helden PD, Gey van Pittius NC, Koehrsen M., Sisk P., Stolte C., White J., Gagneux S., Birren B., Hung D., Murray M., and Galagan J. PloS one, 2012/01/01, Volume 7, Issue 2, p.e26038, (2012) Read More / View Supplemental Materials
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Inferring carbon sources from gene expression profiles using metabolic flux models.Brandes, A., Lun DS, Ip K., Zucker J., Colijn C., Weiner B., and Galagan JE PloS one, 2012/01/01, Volume 7, Issue 5, p.e36947, (2012) Read More / View Supplemental Materials
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Mechanisms of Resistance to Mitogen-Activated Protein Kinase Pathway Inhibition in BRAF-Mutant Melanoma.Goetz, EM, and Garraway LA American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting, 2012/01/01, Volume 32, p.680-684, (2012) Read More / View Supplemental Materials
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Multi-Ethnic Analysis of Lipid-Associated Loci: The NHLBI CARe Project.Musunuru, K., Romaine SP, Lettre G., Wilson JG, Volcik KA, Tsai MY, Taylor HA Jr, Schreiner PJ, Rotter JI, Rich SS, Redline S., Psaty BM, Papanicolaou GJ, Ordovas JM, Liu K., Krauss RM, Glazer NL, Gabriel SB, Fornage M., Cupples LA, et al. PloS one, 2012/01/01, Volume 7, Issue 5, p.e36473, (2012) Read More / View Supplemental Materials
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Non-invasive mapping of the gastrointestinal microbiota identifies children with inflammatory bowel disease.Papa, E., Docktor M., Smillie C., Weber S., Preheim SP, Gevers D., Giannoukos G., Ciulla D., Tabbaa D., Ingram J., Schauer DB, Ward DV, Korzenik JR, Xavier RJ, Bousvaros A., and Alm EJ PloS one, 2012/01/01, Volume 7, Issue 6, p.e39242, (2012) Read More / View Supplemental Materials
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Points of view: Data exploration.Shoresh, N., and Wong B. Nature methods, 2012/01/01, Volume 9, Issue 1, p.5, (2012) Read More / View Supplemental Materials
Statistical characterization of multiple-reaction monitoring mass spectrometry (MRM-MS) assays for quantitative proteomics.Mani, D. R., Abbatiello SE, and Carr SA BMC bioinformatics, 2012/01/01, Volume 13 Suppl 16, p.S9, (2012) Read More / View Supplemental Materials
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Three-dimensional genome architecture influences partner selection for chromosomal translocations in human disease.Engreitz, JM, Agarwala V., and Mirny LA PloS one, 2012/01/01, Volume 7, Issue 9, p.e44196, (2012) Read More / View Supplemental Materials
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iTRAQ labeling is superior to mTRAQ for quantitative global proteomics and phosphoproteomics.Mertins, P., Udeshi ND, Clauser KR, Mani D. R., Patel J., Ong SE, Jaffe JD, and Carr SA Molecular & cellular proteomics : MCP, 2011/12/30, (2012) Read More / View Supplemental Materials
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Quantitative assessment of ChIP-grade antbodies directed against histone modifications reveals patterns of co-occurring marks on histone protein moleculesPeach, Sally E., Rudomin Emily L., Udeshi Namrata D., Carr Steven A., and Jaffe Jacob D. Molecular & Cellular Proteomics, (2012) Read More / View Supplemental Materials
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2011
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia.Wang, L., Lawrence MS, Wan Y., Stojanov P., Sougnez C., Stevenson K., Werner L., Sivachenko A., Deluca DS, Zhang L., Zhang W., Vartanov AR, Fernandes SM, Goldstein NR, Folco EG, Cibulskis K., Tesar B., Sievers QL, Shefler E., Gabriel S., et al. The New England journal of medicine, 2011/12/29, Volume 365, Issue 26, p.2497-506, (2011) Read More / View Supplemental Materials
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Unbiased binding assays for discovering small-molecule probes and drugs.Kemp, MM, Weïwer M., and Koehler AN Bioorganic & medicinal chemistry, 2011/12/24, (2011) Read More / View Supplemental Materials
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Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells.Ram, O., Goren A., Amit I., Shoresh N., Yosef N., Ernst J., Kellis M., Gymrek M., Issner R., Coyne M., Durham T., Zhang X., Donaghey J., Epstein CB, Regev A., and Bernstein BE Cell, 2011/12/23, Volume 147, Issue 7, p.1628-39, (2011) Read More / View Supplemental Materials
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Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc(1) Inhibitors.Urgaonkar, S., Cortese JF, Patel V., Ross L., Clish CB, Serrano AE, Cromwell M., Duraisingh MT, Wirth DF, Clardy J., and Mazitschek R. Chemistry & biology, 2011/12/23, Volume 18, Issue 12, p.1602-10, (2011) Read More / View Supplemental Materials
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The microbial opsin family of optogenetic tools.Zhang, F., Vierock J., Yizhar O., Fenno LE, Tsunoda S., Kianianmomeni A., Prigge M., Berndt A., Cushman J., Polle J., Magnuson J., Hegemann P., and Deisseroth K. Cell, 2011/12/23, Volume 147, Issue 7, p.1446-57, (2011) Read More / View Supplemental Materials
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Inter-laboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for quantifying proteins in plasma.Kuhn, E., Whiteaker JR, Mani D. R., Jackson AM, Zhao L., Pope ME, Smith D., Rivera KD, Anderson NL, Skates SJ, Pearson TW, Paulovich AG, and Carr SA Molecular & cellular proteomics : MCP, 2011/12/22, (2011) Read More / View Supplemental Materials
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Dynamics of dengue disease severity determined by the interplay between viral genetics and serotype-specific immunity.Ohainle, M., Balmaseda A., Macalalad AR, Tellez Y., Zody MC, Saborío S., Nuñez A., Lennon NJ, Birren BW, Gordon A., Henn MR, and Harris E. Science translational medicine, 2011/12/21, Volume 3, Issue 114, p.114ra128, (2011) Read More / View Supplemental Materials
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Detecting novel associations in large data sets.Reshef, DN, Reshef YA, Finucane HK, Grossman SR, McVean G., Turnbaugh PJ, Lander E. S., Mitzenmacher M., and Sabeti PC Science (New York, N.Y.), 2011/12/16, Volume 334, Issue 6062, p.1518-24, (2011) Read More / View Supplemental Materials
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Experimental and analytical tools for studying the human microbiome.Kuczynski, J., Lauber CL, Walters WA, Parfrey LW, Clemente JC, Gevers D., and Knight R. Nature reviews. Genetics, 2011/12/16, Volume 13, Issue 1, p.47-58, (2011) Read More / View Supplemental Materials
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Glioblastoma-Derived Epidermal Growth Factor Receptor Carboxyl-Terminal Deletion Mutants Are Transforming and Are Sensitive to EGFR-Directed Therapies.Cho, J., Pastorino S., Zeng Q., Xu X., Johnson W., Vandenberg S., Verhaak R., Cherniack AD, Watanabe H., Dutt A., Kwon J., Chao YS, Onofrio RC, Chiang D., Yuza Y., Kesari S., and Meyerson M. Cancer research, 2011/12/15, Volume 71, Issue 24, p.7587-96, (2011) Read More / View Supplemental Materials
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Application of genomics to field investigations of malaria by the international centers of excellence for malaria research.Volkman, SK, Ndiaye D., Diakite M., Koita OA, Nwakanma D., Daniels RF, Park DJ, Neafsey DE, Muskavitch MA, Krogstad DJ, Sabeti PC, Hartl DL, and Wirth DF Acta tropica, 2011/12/13, (2011) Read More / View Supplemental Materials
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Genome-wide Association of Copy-Number Variation Reveals an Association between Short Stature and the Presence of Low-Frequency Genomic Deletions.Dauber, A., Yu Y., Turchin MC, Chiang CW, Meng YA, Demerath EW, Patel SR, Rich SS, Rotter JI, Schreiner PJ, Wilson JG, Shen Y., Wu BL, and Hirschhorn JN American journal of human genetics, 2011/12/09, Volume 89, Issue 6, p.751-9, (2011) Read More / View Supplemental Materials
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The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.Naba, A., Clauser KR, Hoersch S., Liu H., Carr SA, and Hynes R. O. Molecular & cellular proteomics : MCP, 2011/12/09, (2011) Read More / View Supplemental Materials
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The changing face of genomics.Kellis, M. Genome biology, 2011/12/08, Volume 5, Issue 5, p.324, (2011) Read More / View Supplemental Materials
Chemical genomics: probing protein function using small molecules.Wagner, BK, Haggarty SJ, and Clemons PA American journal of pharmacogenomics : genomics-related research in drug development and clinical practice, 2011/12/08, Volume 4, Issue 5, p.313-20, (2011) Read More / View Supplemental Materials
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Chromosome substitution strains: a new way to study genetically complex traits.Hill, AE, Lander E. S., and Nadeau JH Methods in molecular medicine, 2011/12/08, Volume 128, p.153-72, (2011) Read More / View Supplemental Materials
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Disease gene discovery through integrative genomics.Giallourakis, C., Henson C., Reich M., Xie X., and Mootha VK Annual review of genomics and human genetics, 2011/12/08, Volume 6, p.381-406, (2011) Read More / View Supplemental Materials
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Global nucleosome occupancy in yeast.Bernstein, BE, Liu CL, Humphrey EL, Perlstein EO, and Schreiber SL Genome biology, 2011/12/08, Volume 5, Issue 9, p.R62, (2011) Read More / View Supplemental Materials
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