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2012
High-resolution analysis of intrahost genetic diversity in dengue virus serotype 1 infection identifies mixed infections.Thai, KT, Henn MR, Zody MC, Tricou V., Nguyet NM, Charlebois P., Lennon NJ, Green L., de Vries PJ, Hien TT, Farrar J., van Doorn HR, de Jong MD, Birren BW, Holmes EC, and Simmons CP Journal of virology, 2012/01/01, Volume 86, Issue 2, p.835-43, (2012) Read More / View Supplemental Materials
Abstract
High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing.Wagle, N., Berger MF, Davis MJ, Blumenstiel B., DeFelice M., Pochanard P., Ducar M., Van Hummelen P., Macconaill LE, Hahn WC, Meyerson M., Gabriel SB, and Garraway LA Cancer discovery, 2012/01/01, Volume 2, Issue 1, p.82-93, (2012) Read More / View Supplemental Materials
Abstract
Independent Large Scale Duplications in Multiple M. tuberculosis Lineages Overlapping the Same Genomic Region.Weiner, B., Gomez J., Victor TC, Warren RM, Sloutsky A., Plikaytis BB, Posey JE, van Helden PD, Gey van Pittius NC, Koehrsen M., Sisk P., Stolte C., White J., Gagneux S., Birren B., Hung D., Murray M., and Galagan J. PloS one, 2012/01/01, Volume 7, Issue 2, p.e26038, (2012) Read More / View Supplemental Materials
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Inferring carbon sources from gene expression profiles using metabolic flux models.Brandes, A., Lun DS, Ip K., Zucker J., Colijn C., Weiner B., and Galagan JE PloS one, 2012/01/01, Volume 7, Issue 5, p.e36947, (2012) Read More / View Supplemental Materials
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Mechanisms of Resistance to Mitogen-Activated Protein Kinase Pathway Inhibition in BRAF-Mutant Melanoma.Goetz, EM, and Garraway LA American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting, 2012/01/01, Volume 32, p.680-684, (2012) Read More / View Supplemental Materials
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Multi-Ethnic Analysis of Lipid-Associated Loci: The NHLBI CARe Project.Musunuru, K., Romaine SP, Lettre G., Wilson JG, Volcik KA, Tsai MY, Taylor HA Jr, Schreiner PJ, Rotter JI, Rich SS, Redline S., Psaty BM, Papanicolaou GJ, Ordovas JM, Liu K., Krauss RM, Glazer NL, Gabriel SB, Fornage M., Cupples LA, et al. PloS one, 2012/01/01, Volume 7, Issue 5, p.e36473, (2012) Read More / View Supplemental Materials
Abstract
Non-invasive mapping of the gastrointestinal microbiota identifies children with inflammatory bowel disease.Papa, E., Docktor M., Smillie C., Weber S., Preheim SP, Gevers D., Giannoukos G., Ciulla D., Tabbaa D., Ingram J., Schauer DB, Ward DV, Korzenik JR, Xavier RJ, Bousvaros A., and Alm EJ PloS one, 2012/01/01, Volume 7, Issue 6, p.e39242, (2012) Read More / View Supplemental Materials
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Points of view: Data exploration.Shoresh, N., and Wong B. Nature methods, 2012/01/01, Volume 9, Issue 1, p.5, (2012) Read More / View Supplemental Materials
Statistical characterization of multiple-reaction monitoring mass spectrometry (MRM-MS) assays for quantitative proteomics.Mani, D. R., Abbatiello SE, and Carr SA BMC bioinformatics, 2012/01/01, Volume 13 Suppl 16, p.S9, (2012) Read More / View Supplemental Materials
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Three-dimensional genome architecture influences partner selection for chromosomal translocations in human disease.Engreitz, JM, Agarwala V., and Mirny LA PloS one, 2012/01/01, Volume 7, Issue 9, p.e44196, (2012) Read More / View Supplemental Materials
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iTRAQ labeling is superior to mTRAQ for quantitative global proteomics and phosphoproteomics.Mertins, P., Udeshi ND, Clauser KR, Mani D. R., Patel J., Ong SE, Jaffe JD, and Carr SA Molecular & cellular proteomics : MCP, 2011/12/30, (2012) Read More / View Supplemental Materials
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Quantitative assessment of ChIP-grade antbodies directed against histone modifications reveals patterns of co-occurring marks on histone protein moleculesPeach, Sally E., Rudomin Emily L., Udeshi Namrata D., Carr Steven A., and Jaffe Jacob D. Molecular & Cellular Proteomics, (2012) Read More / View Supplemental Materials
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2011
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia.Wang, L., Lawrence MS, Wan Y., Stojanov P., Sougnez C., Stevenson K., Werner L., Sivachenko A., Deluca DS, Zhang L., Zhang W., Vartanov AR, Fernandes SM, Goldstein NR, Folco EG, Cibulskis K., Tesar B., Sievers QL, Shefler E., Gabriel S., et al. The New England journal of medicine, 2011/12/29, Volume 365, Issue 26, p.2497-506, (2011) Read More / View Supplemental Materials
Abstract
Unbiased binding assays for discovering small-molecule probes and drugs.Kemp, MM, Weïwer M., and Koehler AN Bioorganic & medicinal chemistry, 2011/12/24, (2011) Read More / View Supplemental Materials
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Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells.Ram, O., Goren A., Amit I., Shoresh N., Yosef N., Ernst J., Kellis M., Gymrek M., Issner R., Coyne M., Durham T., Zhang X., Donaghey J., Epstein CB, Regev A., and Bernstein BE Cell, 2011/12/23, Volume 147, Issue 7, p.1628-39, (2011) Read More / View Supplemental Materials
Abstract
Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc(1) Inhibitors.Urgaonkar, S., Cortese JF, Patel V., Ross L., Clish CB, Serrano AE, Cromwell M., Duraisingh MT, Wirth DF, Clardy J., and Mazitschek R. Chemistry & biology, 2011/12/23, Volume 18, Issue 12, p.1602-10, (2011) Read More / View Supplemental Materials
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The microbial opsin family of optogenetic tools.Zhang, F., Vierock J., Yizhar O., Fenno LE, Tsunoda S., Kianianmomeni A., Prigge M., Berndt A., Cushman J., Polle J., Magnuson J., Hegemann P., and Deisseroth K. Cell, 2011/12/23, Volume 147, Issue 7, p.1446-57, (2011) Read More / View Supplemental Materials
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Inter-laboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for quantifying proteins in plasma.Kuhn, E., Whiteaker JR, Mani D. R., Jackson AM, Zhao L., Pope ME, Smith D., Rivera KD, Anderson NL, Skates SJ, Pearson TW, Paulovich AG, and Carr SA Molecular & cellular proteomics : MCP, 2011/12/22, (2011) Read More / View Supplemental Materials
Abstract
Dynamics of dengue disease severity determined by the interplay between viral genetics and serotype-specific immunity.Ohainle, M., Balmaseda A., Macalalad AR, Tellez Y., Zody MC, Saborío S., Nuñez A., Lennon NJ, Birren BW, Gordon A., Henn MR, and Harris E. Science translational medicine, 2011/12/21, Volume 3, Issue 114, p.114ra128, (2011) Read More / View Supplemental Materials
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Detecting novel associations in large data sets.Reshef, DN, Reshef YA, Finucane HK, Grossman SR, McVean G., Turnbaugh PJ, Lander E. S., Mitzenmacher M., and Sabeti PC Science (New York, N.Y.), 2011/12/16, Volume 334, Issue 6062, p.1518-24, (2011) Read More / View Supplemental Materials
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Experimental and analytical tools for studying the human microbiome.Kuczynski, J., Lauber CL, Walters WA, Parfrey LW, Clemente JC, Gevers D., and Knight R. Nature reviews. Genetics, 2011/12/16, Volume 13, Issue 1, p.47-58, (2011) Read More / View Supplemental Materials
Abstract
Glioblastoma-Derived Epidermal Growth Factor Receptor Carboxyl-Terminal Deletion Mutants Are Transforming and Are Sensitive to EGFR-Directed Therapies.Cho, J., Pastorino S., Zeng Q., Xu X., Johnson W., Vandenberg S., Verhaak R., Cherniack AD, Watanabe H., Dutt A., Kwon J., Chao YS, Onofrio RC, Chiang D., Yuza Y., Kesari S., and Meyerson M. Cancer research, 2011/12/15, Volume 71, Issue 24, p.7587-96, (2011) Read More / View Supplemental Materials
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Application of genomics to field investigations of malaria by the international centers of excellence for malaria research.Volkman, SK, Ndiaye D., Diakite M., Koita OA, Nwakanma D., Daniels RF, Park DJ, Neafsey DE, Muskavitch MA, Krogstad DJ, Sabeti PC, Hartl DL, and Wirth DF Acta tropica, 2011/12/13, (2011) Read More / View Supplemental Materials
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Genome-wide Association of Copy-Number Variation Reveals an Association between Short Stature and the Presence of Low-Frequency Genomic Deletions.Dauber, A., Yu Y., Turchin MC, Chiang CW, Meng YA, Demerath EW, Patel SR, Rich SS, Rotter JI, Schreiner PJ, Wilson JG, Shen Y., Wu BL, and Hirschhorn JN American journal of human genetics, 2011/12/09, Volume 89, Issue 6, p.751-9, (2011) Read More / View Supplemental Materials
Abstract
The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.Naba, A., Clauser KR, Hoersch S., Liu H., Carr SA, and Hynes R. O. Molecular & cellular proteomics : MCP, 2011/12/09, (2011) Read More / View Supplemental Materials
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The changing face of genomics.Kellis, M. Genome biology, 2011/12/08, Volume 5, Issue 5, p.324, (2011) Read More / View Supplemental Materials
Chemical genomics: probing protein function using small molecules.Wagner, BK, Haggarty SJ, and Clemons PA American journal of pharmacogenomics : genomics-related research in drug development and clinical practice, 2011/12/08, Volume 4, Issue 5, p.313-20, (2011) Read More / View Supplemental Materials
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Chromosome substitution strains: a new way to study genetically complex traits.Hill, AE, Lander E. S., and Nadeau JH Methods in molecular medicine, 2011/12/08, Volume 128, p.153-72, (2011) Read More / View Supplemental Materials
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Disease gene discovery through integrative genomics.Giallourakis, C., Henson C., Reich M., Xie X., and Mootha VK Annual review of genomics and human genetics, 2011/12/08, Volume 6, p.381-406, (2011) Read More / View Supplemental Materials
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Global nucleosome occupancy in yeast.Bernstein, BE, Liu CL, Humphrey EL, Perlstein EO, and Schreiber SL Genome biology, 2011/12/08, Volume 5, Issue 9, p.R62, (2011) Read More / View Supplemental Materials
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Large-scale discovery and validation of functional elements in the human genome.Bernstein, BE, and Kellis M. Genome biology, 2011/12/08, Volume 6, Issue 3, p.312, (2011) Read More / View Supplemental Materials
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A method for high-throughput gene expression signature analysis.Peck, D., Crawford ED, Ross KN, Stegmaier K., Golub T. R., and Lamb J. Genome biology, 2011/12/08, Volume 7, Issue 7, p.R61, (2011) Read More / View Supplemental Materials
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Methods in comparative genomics: genome correspondence, gene identification and regulatory motif discovery.Kellis, M., Patterson N., Birren B., Berger B., and Lander E. S. Journal of computational biology : a journal of computational molecular cell biology, 2011/12/08, Volume 11, Issue 2-3, p.319-55, (2011) Read More / View Supplemental Materials
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Progress towards identifying inflammatory bowel disease susceptibility genes.Rioux, JD Novartis Foundation symposium, 2011/12/08, Volume 263, p.3-11; discussion 11-6, 211-8, (2011) Read More / View Supplemental Materials
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Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis.Meissner, A., Gnirke A., Bell GW, Ramsahoye B., Lander E. S., and Jaenisch R. Nucleic acids research, 2011/12/08, Volume 33, Issue 18, p.5868-77, (2011) Read More / View Supplemental Materials
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Transferability of tag SNPs to capture common genetic variation in DNA repair genes across multiple populations.de Bakker, PI, Graham RR, Altshuler D., Henderson BE, and Haiman CA Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 2011/12/08, p.478-86, (2011) Read More / View Supplemental Materials
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The use of chromatin immunoprecipitation assays in genome-wide analyses of histone modifications.Bernstein, BE, Humphrey EL, Liu CL, and Schreiber SL Methods in enzymology, 2011/12/08, Volume 376, p.349-60, (2011) Read More / View Supplemental Materials
What makes us human?Mikkelsen, TS Genome biology, 2011/12/08, Volume 5, Issue 8, p.238, (2011) Read More / View Supplemental Materials
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A Human Islet Cell Culture System for High-Throughput Screening.Walpita, D., Hasaka T., Spoonamore J., Vetere A., Takane KK, Fomina-Yadlin D., Fiaschi-Taesch N., Shamji A., Clemons PA, Stewart AF, Schreiber SL, and Wagner BK Journal of biomolecular screening, 2011/12/07, (2011) Read More / View Supplemental Materials
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Amplification of CRKL Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non-Small Cell Lung Cancers.Cheung, HW, Du J., Boehm JS, He F., Weir BA, Wang X., Butaney M., Sequist LV, Luo B., Engelman JA, Root DE, Meyerson M., Golub T. R., Jänne PA, and Hahn WC Cancer discovery, 2011/12/01, Volume 1, Issue 7, p.608-25, (2011) Read More / View Supplemental Materials
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Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.Patsopoulos, NA, the Bayer Pharma MS Genetics Working Group, the Steering Committees of Studies Evaluating IFNβ-1b and a CCR1-Antagonist ANZgene, and de Bakker PI Annals of neurology, 2011/12/01, Volume 70, Issue 6, p.897-912, (2011) Read More / View Supplemental Materials
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Genomic distribution and inter-sample variation of non-CpG methylation across human cell types.Ziller, MJ, Müller F., Liao J., Zhang Y., Gu H., Bock C., Boyle P., Epstein CB, Bernstein BE, Lengauer T., Gnirke A., and Meissner A. PLoS genetics, 2011/12/01, Volume 7, Issue 12, p.e1002389, (2011) Read More / View Supplemental Materials
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Identification of small-molecule inhibitors of Trypansoma cruzi replication.Germain, AR, Carmody LC, Dockendorff C., Galan-Rodriguez C., Rodriguez A., Johnston S., Bittker JA, Macpherson L., Dandapani S., Palmer M., Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2011/12/01, Volume 21, Issue 23, p.7197-200, (2011) Read More / View Supplemental Materials
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Image-based genome-wide siRNA screen identifies selective autophagy factors.Orvedahl, A., Sumpter R Jr, Xiao G., Ng A., Zou Z., Tang Y., Narimatsu M., Gilpin C., Sun Q., Roth M., Forst CV, Wrana JL, Zhang YE, Luby-Phelps K., Xavier RJ, Xie Y., and Levine B. Nature, 2011/12/01, Volume 480, Issue 7375, p.113-7, (2011) Read More / View Supplemental Materials
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A phylogenetic analysis using full-length viral genomes of South American dengue serotype 3 in consecutive Venezuelan outbreaks reveals a novel NS5 mutation.Schmidt, DJ, Pickett BE, Camacho D., Comach G., Xhaja K., Lennon NJ, Rizzolo K., de Bosch N., Becerra A., Nogueira ML, Mondini A., da Silva EV, Vasconcelos PF, Muñoz-Jordán JL, Santiago GA, Ocazionez R., Gehrke L., Lefkowitz EJ, Birren BW, Henn MR, et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2011/12/01, Volume 11, Issue 8, p.2011-9, (2011) Read More / View Supplemental Materials
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Visualization of parameter space for image analysis.Pretorius, AJ, Bray MA, Carpenter AE, and Ruddle RA IEEE transactions on visualization and computer graphics, 2011/12/01, Volume 17, Issue 12, p.2402-11, (2011) Read More / View Supplemental Materials
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What can genetic studies of left ventricular mass tell us?Newton-Cheh, C. Circulation. Cardiovascular genetics, 2011/12/01, Volume 4, Issue 6, p.581-4, (2011) Read More / View Supplemental Materials
The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease.Yu, L., Shulman JM, Chibnik L., Leurgans S., Schneider JA, De Jager PL, and Bennett DA Aging cell, 2011/11/28, (2011) Read More / View Supplemental Materials
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Genetic Defect in CYP24A1, the Vitamin D 24-Hydroxylase Gene, in a Patient with Severe Infantile Hypercalcemia.Dauber, A., Nguyen TT, Sochett E., Cole DE, Horst R., Abrams SA, Carpenter TO, and Hirschhorn JN The Journal of clinical endocrinology and metabolism, 2011/11/23, (2011) Read More / View Supplemental Materials
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Low Plasma Level of Atrial Natriuretic Peptide Predicts Development of Diabetes: The Prospective Malmo Diet and Cancer Study.Magnusson, M., Jujic A., Hedblad B., Engström G., Persson M., Struck J., Morgenthaler NG, Nilsson P., Newton-Cheh C., Wang TJ, and Melander O. The Journal of clinical endocrinology and metabolism, 2011/11/23, (2011) Read More / View Supplemental Materials
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PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling.Shrestha, Y., Schafer EJ, Boehm JS, Thomas SR, He F., Du J., Wang S., Barretina J., Weir BA, Zhao JJ, Polyak K., Golub T. R., Beroukhim R., and Hahn WC Oncogene, 2011/11/21, (2011) Read More / View Supplemental Materials
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GenomeView: a next-generation genome browser.Abeel, T., Van Parys T., Saeys Y., Galagan J., and Van de Peer Y. Nucleic acids research, 2011/11/18, (2011) Read More / View Supplemental Materials
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Strategies to discover regulatory circuits of the mammalian immune system.Amit, I., Regev A., and Hacohen N. Nature reviews. Immunology, 2011/11/18, Volume 11, Issue 12, p.873-80, (2011) Read More / View Supplemental Materials
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Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development.Singh, KK, De Rienzo G., Drane L., Mao Y., Flood Z., Madison J., Ferreira M., Bergen S., King C., Sklar P., Sive H., and Tsai LH Neuron, 2011/11/17, Volume 72, Issue 4, p.545-58, (2011) Read More / View Supplemental Materials
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Systematic discovery of TLR signaling components delineates viral-sensing circuits.Chevrier, N., Mertins P., Artyomov MN, Shalek AK, Iannacone M., Ciaccio MF, Gat-Viks I., Tonti E., Degrace MM, Clauser KR, Garber M., Eisenhaure TM, Yosef N., Robinson J., Sutton A., Andersen MS, Root DE, von Andrian U., Jones RB, Park H., et al. Cell, 2011/11/11, Volume 147, Issue 4, p.853-67, (2011) Read More / View Supplemental Materials
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RAS Mutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors.Oberholzer, PA, Kee D., Dziunycz P., Sucker A., Kamsukom N., Jones R., Roden C., Chalk CJ, Ardlie K., Palescandolo E., Piris A., Macconaill LE, Robert C., Hofbauer GF, McArthur GA, Schadendorf D., and Garraway LA Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011/11/07, (2011) Read More / View Supplemental Materials
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Comprehensive proteomic study identifies serpin and cystatin antiproteases as novel correlates of HIV-1 resistance in the cervicovaginal mucosa of female sex workers.Burgener, A., Rahman S., Ahmad R., Lajoie J., Ramdahin S., Mesa C., Brunet S., Wachihi C., Kimani J., Fowke K., Carr S., Plummer F., and Ball TB Journal of proteome research, 2011/11/04, Volume 10, Issue 11, p.5139-49, (2011) Read More / View Supplemental Materials
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Guiding DNA methylation.Meissner, A. Cell stem cell, 2011/11/04, Volume 9, Issue 5, p.388-90, (2011) Read More / View Supplemental Materials
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A genome-wide scan for common variants affecting the rate of age-related cognitive decline.De Jager, PL, Shulman JM, Chibnik LB, Keenan BT, Raj T., Wilson RS, Yu L., Leurgans SE, Tran D., Aubin C., Anderson CD, Biffi A., Corneveaux JJ, Huentelman MJ, Alzheimer's Disease Neuroimaging Initiative, Rosand J., Daly M. J., Myers AJ, Reiman EM, Bennett DA, et al. Neurobiology of aging, 2011/11/03, (2011) Read More / View Supplemental Materials
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Synaptic Deficits Are Rescued in the p25/Cdk5 Model of Neurodegeneration by the Reduction of β-Secretase (BACE1).Giusti-Rodríguez, P., Gao J., Gräff J., Rei D., Soda T., and Tsai LH The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011/11/02, Volume 31, Issue 44, p.15751-6, (2011) Read More / View Supplemental Materials
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Unfolding neurodevelopmental disorders: found in translation.Ting, JT, and Feng G. Nature medicine, 2011/11/02, Volume 17, Issue 11, p.1352-3, (2011) Read More / View Supplemental Materials
Distribution Pattern of Plasmodium falciparum Chloroquine Transporter (pfcrt) Gene Haplotypes in Sri Lanka 1996-2006.Zhang, JJ, Senaratne TN, Daniels R., Valim C., Alifrangis M., Amerasinghe P., Konradsen F., Rajakaruna R., Wirth DF, and Karunaweera ND The American journal of tropical medicine and hygiene, 2011/11/01, Volume 85, Issue 5, p.811-4, (2011) Read More / View Supplemental Materials
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Evolutionary divergence of intrinsic and trans-regulated nucleosome positioning sequences reveals plastic rules for chromatin organization.Tsankov, A., Yanagisawa Y., Rhind N., Regev A., and Rando OJ Genome research, 2011/11/01, Volume 21, Issue 11, p.1851-62, (2011) Read More / View Supplemental Materials
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A face in the crowd: recognizing peptides through database search.Eng, JK, Searle BC, Clauser KR, and Tabb DL Molecular & cellular proteomics : MCP, 2011/11/01, Volume 10, Issue 11, p.R111.009522, (2011) Read More / View Supplemental Materials
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Master Data Management: Getting your House in Order.Seiler, KP, Bodycombe NE, Hawkins T., Shell R., Lemon A., Souza A., and Clemons PA Combinatorial chemistry & high throughput screening, 2011/11/01, Volume 14, Issue 9, p.749-56, (2011) Read More / View Supplemental Materials
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A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data.Li, H. Bioinformatics (Oxford, England), 2011/11/01, Volume 27, Issue 21, p.2987-93, (2011) Read More / View Supplemental Materials
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The two-component sensor kinase KinB acts as a non-canonical switch between acute and chronic infection.Chand, NS, and Hung DT Virulence, 2011/11/01, Volume 2, Issue 6, p.553-8, (2011) Read More / View Supplemental Materials
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Reply to "More on color blindness".Wong, B. Nature methods, 2011/10/28, Volume 8, Issue 11, p.891-2, (2011) Read More / View Supplemental Materials
ANAT: a tool for constructing and analyzing functional protein networks.Yosef, N., Zalckvar E., Rubinstein AD, Homilius M., Atias N., Vardi L., Berman I., Zur H., Kimchi A., Ruppin E., and Sharan R. Science signaling, 2011/10/25, Volume 4, Issue 196, p.pl1, (2011) Read More / View Supplemental Materials
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A rare penetrant mutation in CFH confers high risk of age-related macular degeneration.Raychaudhuri, S., Iartchouk O., Chin K., Tan PL, Tai AK, Ripke S., Gowrisankar S., Vemuri S., Montgomery K., Yu Y., Reynolds R., Zack DJ, Campochiaro B., Campochiaro P., Katsanis N., Daly M. J., and Seddon JM Nature genetics, 2011/10/23, Volume 43, Issue 12, p.1232-6, (2011) Read More / View Supplemental Materials
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Diastereoselective control of intramolecular aza-Michael reactions using achiral catalysts.Zhong, C., Wang Y., Hung AW, Schreiber SL, and Young DW Organic letters, 2011/10/21, Volume 13, Issue 20, p.5556-9, (2011) Read More / View Supplemental Materials
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Genomic analysis identifies association of Fusobacterium with colorectal carcinoma.Kostic, AD, Gevers D., Pedamallu CS, Michaud M., Duke F., Earl AM, Ojesina AI, Jung J., Bass AJ, Tabernero J., Baselga J., Liu C., Shivdasani RA, Ogino S., Birren BW, Huttenhower C., Garrett WS, and Meyerson M. Genome research, 2011/10/18, (2011) Read More / View Supplemental Materials
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A high-resolution map of human evolutionary constraint using 29 mammals.Lindblad-Toh, K., Garber M., Zuk O., Lin MF, Parker BJ, Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward LD, Lowe CB, Holloway AK, Clamp M., Gnerre S., Alföldi J., Beal K., Chang J., Clawson H., Cuff J., et al. Nature, 2011/10/12, Volume 478, Issue 7370, p.476-82, (2011) Read More / View Supplemental Materials
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Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.Rivas, MA, Beaudoin M., Gardet A., Stevens C., Sharma Y., Zhang CK, Boucher G., Ripke S., Ellinghaus D., Burtt N., Fennell T., Kirby A., Latiano A., Goyette P., Green T., Halfvarson J., Haritunians T., Korn JM, Kuruvilla F., Lagacé C., et al. Nature genetics, 2011/10/09, Volume 43, Issue 11, p.1066-73, (2011) Read More / View Supplemental Materials
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Diversity-oriented synthesis of 13- to 18-membered macrolactams via ring-closing metathesis.Dandapani, S., Lowe JT, Comer E., and Marcaurelle LA The Journal of organic chemistry, 2011/10/07, Volume 76, Issue 19, p.8042-8, (2011) Read More / View Supplemental Materials
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Approaches to Fungal Genome Annotation.Haas, BJ, Zeng Q., Pearson MD, Cuomo CA, and Wortman JR Mycology, 2011/10/03, Volume 2, Issue 3, p.118-141, (2011) Read More / View Supplemental Materials
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Comparative genomic analysis of human fungal pathogens causing paracoccidioidomycosis.Desjardins, CA, Champion MD, Holder JW, Muszewska A., Goldberg J., Bailão AM, Brigido MM, Ferreira ME, Garcia AM, Grynberg M., Gujja S., Heiman DI, Henn MR, Kodira CD, León-Narváez H., Longo LV, Ma LJ, Malavazi I., Matsuo AL, Morais FV, et al. PLoS genetics, 2011/10/01, Volume 7, Issue 10, p.e1002345, (2011) Read More / View Supplemental Materials
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Genomic risk of hepatitis C-related hepatocellular carcinoma.Hoshida, Y., Fuchs BC, and Tanabe KK Journal of hepatology, 2011/09/29, (2011) Read More / View Supplemental Materials
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Whole-genome chromatin profiling from limited numbers of cells using nano-ChIP-seq.Adli, M., and Bernstein BE Nature protocols, 2011/09/29, Volume 6, Issue 10, p.1656-68, (2011) Read More / View Supplemental Materials
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Corridors of migrating neurons in the human brain and their decline during infancy.Sanai, N., Nguyen T., Ihrie RA, Mirzadeh Z., Tsai HH, Wong M., Gupta N., Berger MS, Huang E., Garcia-Verdugo JM, Rowitch DH, and Alvarez-Buylla A. Nature, 2011/09/28, Volume 478, Issue 7369, p.382-6, (2011) Read More / View Supplemental Materials
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Workflow and Metrics for Image Quality Control in Large-Scale High-Content Screens.Bray, MA, Fraser AN, Hasaka TP, and Carpenter AE Journal of biomolecular screening, 2011/09/28, (2011) Read More / View Supplemental Materials
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ContEst: estimating cross-contamination of human samples in next-generation sequencing data.Cibulskis, K., McKenna A., Fennell T., Banks E., DePristo M., and Getz G. Bioinformatics (Oxford, England), 2011/09/15, Volume 27, Issue 18, p.2601-2, (2011) Read More / View Supplemental Materials
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The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells.Wilson, AJ, Holson E., Wagner F., Zhang YL, Fass DM, Haggarty SJ, Bhaskara S., Hiebert SW, Schreiber SL, and Khabele D. Cancer biology & therapy, 2011/09/15, Volume 12, Issue 6, p.484-93, (2011) Read More / View Supplemental Materials
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The genome of th17 cell-inducing segmented filamentous bacteria reveals extensive auxotrophy and adaptations to the intestinal environment.Sczesnak, A., Segata N., Qin X., Gevers D., Petrosino JF, Huttenhower C., Littman DR, and Ivanov II Cell host & microbe, 2011/09/15, Volume 10, Issue 3, p.260-72, (2011) Read More / View Supplemental Materials
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Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses.Cabili, MN, Trapnell C., Goff L., Koziol M., Tazon-Vega B., Regev A., and Rinn JL Genes & development, 2011/09/15, Volume 25, Issue 18, p.1915-27, (2011) Read More / View Supplemental Materials
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Piperazinyl quinolines as chemosensitizers to increase fluconazole susceptibility of Candida albicans clinical isolates.Youngsaye, W., Vincent B., Hartland CL, Morgan BJ, Buhrlage SJ, Johnston S., Bittker JA, Macpherson L., Dandapani S., Palmer M., Whitesell L., Lindquist S., Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2011/09/15, Volume 21, Issue 18, p.5502-5, (2011) Read More / View Supplemental Materials
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Computational and statistical approaches to analyzing variants identified by exome sequencing.Stitziel, NO, Kiezun A., and Sunyaev S. Genome biology, 2011/09/14, Volume 12, Issue 9, p.227, (2011) Read More / View Supplemental Materials
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Optimization of Potent Inhibitors of P. falciparum Dihydroorotate Dehydrogenase for the Treatment of Malaria.Skerlj, RT, Bastos CM, Booker ML, Kramer ML, Barker RH Jr, Celatka CA, O'Shea TJ, Munoz B., Sidhu AB, Cortese JF, Wittlin S., Papastogiannidis P., Angulo-Barturen I., Jimenez-Diaz MB, and Sybertz E. ACS medicinal chemistry letters, 2011/09/08, Volume 2, Issue 9, p.708-13, (2011) Read More / View Supplemental Materials
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Synthesis of a novel suppressor of beta-cell apoptosis via diversity-oriented synthesis.Chou, DH, Duvall JR, Gerard B., Liu H., Pandya BA, Suh BC, Forbeck EM, Faloon P., Wagner BK, and Marcaurelle LA ACS medicinal chemistry letters, 2011/09/08, Volume 2, Issue 9, p.698-702, (2011) Read More / View Supplemental Materials
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Mutations in MTFMT underlie a human disorder of formylation causing impaired mitochondrial translation.Tucker, EJ, Hershman SG, Köhrer C., Belcher-Timme CA, Patel J., Goldberger OA, Christodoulou J., Silberstein JM, McKenzie M., Ryan MT, Compton AG, Jaffe JD, Carr SA, Calvo SE, RajBhandary UL, Thorburn DR, and Mootha VK Cell metabolism, 2011/09/07, Volume 14, Issue 3, p.428-34, (2011) Read More / View Supplemental Materials
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Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion.Bass, AJ, Lawrence MS, Brace LE, Ramos AH, Drier Y., Cibulskis K., Sougnez C., Voet D., Saksena G., Sivachenko A., Jing R., Parkin M., Pugh T., Verhaak RG, Stransky N., Boutin AT, Barretina J., Solit DB, Vakiani E., Shao W., et al. Nature genetics, 2011/09/04, Volume 43, Issue 10, p.964-8, (2011) Read More / View Supplemental Materials
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Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels development.Holder, JW, Ulrich JC, DeBono AC, Godfrey PA, Desjardins CA, Zucker J., Zeng Q., Leach AL, Ghiviriga I., Dancel C., Abeel T., Gevers D., Kodira CD, Desany B., Affourtit JP, Birren BW, and Sinskey AJ PLoS genetics, 2011/09/01, Volume 7, Issue 9, p.e1002219, (2011) Read More / View Supplemental Materials
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Leucine-rich repeat (LRR) proteins: integrators of pattern recognition and signaling in immunity.Ng, A., and Xavier RJ Autophagy, 2011/09/01, Volume 7, Issue 9, p.1082-4, (2011) Read More / View Supplemental Materials
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Molecular signatures and prognosis of hepatocellular carcinoma.Hoshida, Y. Minerva gastroenterologica e dietologica, 2011/09/01, Volume 57, Issue 3, p.311-22, (2011) Read More / View Supplemental Materials
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Points of view: arrows.Wong, B. Nature methods, 2011/09/01, Volume 8, Issue 9, p.701, (2011) Read More / View Supplemental Materials
STK33 kinase activity is nonessential in KRAS-dependent cancer cells.Babij, C., Zhang Y., Kurzeja RJ, Munzli A., Shehabeldin A., Fernando M., Quon K., Kassner PD, Ruefli-Brasse AA, Watson VJ, Fajardo F., Jackson A., Zondlo J., Sun Y., Ellison AR, Plewa CA, San MT, Robinson J., McCarter J., Schwandner R., et al. Cancer research, 2011/09/01, Volume 71, Issue 17, p.5818-26, (2011) Read More / View Supplemental Materials
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Clustering with position-specific constraints on variance: applying redescending M-estimators to label-free LC-MS data analysis.Frühwirth, R., Mani D. R., and Pyne S. BMC bioinformatics, 2011/08/31, Volume 12, p.358, (2011) Read More / View Supplemental Materials
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The genome of the green anole lizard and a comparative analysis with birds and mammals.Alföldi, J., Di Palma F., Grabherr M., Williams C., Kong L., Mauceli E., Russell P., Lowe CB, Glor RE, Jaffe JD, Ray DA, Boissinot S., Shedlock AM, Botka C., Castoe TA, Colbourne JK, Fujita MK, Moreno RG, ten Hallers BF, Haussler D., et al. Nature, 2011/08/31, Volume 477, Issue 7366, p.587-91, (2011) Read More / View Supplemental Materials
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lincRNAs act in the circuitry controlling pluripotency and differentiation.Guttman, M., Donaghey J., Carey BW, Garber M., Grenier JK, Munson G., Young G., Lucas AB, Ach R., Bruhn L., Yang X., Amit I., Meissner A., Regev A., Rinn JL, Root DE, and Lander E. S. Nature, 2011/08/28, Volume 477, Issue 7364, p.295-300, (2011) Read More / View Supplemental Materials
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Stem cell gene expression programs influence clinical outcome in human leukemia.Eppert, K., Takenaka K., Lechman ER, Waldron L., Nilsson B., van Galen P., Metzeler KH, Poeppl A., Ling V., Beyene J., Canty AJ, Danska JS, Bohlander SK, Buske C., Minden MD, Golub T. R., Jurisica I., Ebert BL, and Dick JE Nature medicine, 2011/08/28, Volume 17, Issue 9, p.1086-93, (2011) Read More / View Supplemental Materials
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