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  • Showing 1-26 of 26 Results
2008
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancerSetlur, Sunita R., Mertz Kirsten D., Hoshida Yujin, Demichelis Francesca, Lupien Mathieu, Perner Sven, Sboner Andrea, Pawitan Yudi, and Andr Journal of the National Cancer Institute, 2008/06/04/, Volume 100, Issue 11, p.815 - 25, (2008) Read More / View Supplemental Materials
Abstract
SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphomaChen, Linfeng, Monti Stefano, Juszczynski Przemyslaw, Daley John, Chen Wen, Witzig Thomas E., Habermann Thomas M., Kutok Jeffery L., and Shipp Margaret A. Blood, 2008/02/15/, Volume 111, Issue 4, p.2230 - 7, (2008) Read More / View Supplemental Materials
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2007
Assessing the significance of chromosomal aberrations in cancer: methodology and application to gliomaBeroukhim, Rameen, Getz Gad, Nghiemphu Leia, Barretina Jordi, Hsueh Teli, Linhart David, Vivanco Igor, Lee Jeffrey C., Huang Julie H., Alexander Sethu, Du Jinyan, Kau Tweeny, Thomas Roman K., Shah Kinjal, Soto Horacio, Perner Sven, Prensner John, and Debiasi Ralp Proceedings of the National Academy of Sciences of the United States of America, 2007/12/11/, Volume 104, Issue 50, p.20007 - 12, (2007) Read More / View Supplemental Materials
Abstract
Characterizing the cancer genome in lung adenocarcinomaWeir, Barbara A., Woo Michele S., Getz Gad, Perner Sven, Ding Li, Beroukhim Rameen, Lin William M., Province Michael A., Kraja Aldi, Johnson Laura A., Shah Kinjal, Sato Mitsuo, Thomas Roman K., Barletta Justine A., Borecki Ingrid B., Broderick Stephen, and Chang Andre Nature, 2007/12/06/, Volume 450, Issue 7171, p.893 - 8, (2007) Read More / View Supplemental Materials
Abstract
Impaired microRNA processing enhances cellular transformation and tumorigenesisKumar, Madhu S., Lu Jun, Mercer Kim L., Golub Todd R., and Jacks Tyler Nature Genetics, 2007/05//, Volume 39, Issue 5, p.673 - 7, (2007) Read More / View Supplemental Materials
Abstract
Metagene projection for cross-platform, cross-species characterization of global transcriptional statesTamayo, Pablo, Scanfeld Daniel, Ebert Benjamin L., Gillette Michael A., Roberts Charles W. M., and Mesirov Jill P. Proceedings of the National Academy of Sciences of the United States of America, 2007/04/03/, Volume 104, Issue 14, p.5959 - 64, (2007) Read More / View Supplemental Materials
Abstract
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcomaStegmaier, Kimberly, Wong Jenny S., Ross Kenneth N., Chow Kwan T., Peck David, Wright Renee D., Lessnick Stephen L., Kung Andrew L., and Golub Todd R. PLoS Medicine, 2007/04//, Volume 4, Issue 4, p.e122 - e122, (2007) Read More / View Supplemental Materials
Abstract
Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomasPolo, Jose M., Juszczynski Przemyslaw, Monti Stefano, Cerchietti Leandro, Ye Kenny, Greally John M., Shipp Margaret, and Melnick Ari Proceedings of the National Academy of Sciences of the United States of America, 2007/02/27/, Volume 104, Issue 9, p.3207 - 12, (2007) Read More / View Supplemental Materials
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2006
Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signalingKobayashi, Susumu, Shimamura Takeshi, Monti Stefano, Steidl Ulrich, Hetherington Christopher J., Lowell April M., Golub Todd, Meyerson Matthew, Tenen Daniel G., Shapiro Geoffrey I., and Halmos Bal Cancer Research, 2006/12/01/, Volume 66, Issue 23, p.11389 - 98, (2006) Read More / View Supplemental Materials
Abstract
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulatorsHieronymus, Haley, Lamb Justin, Ross Kenneth N., Peng Xiao P., Clement Cristina, Rodina Anna, Nieto Maria, Du Jinyan, Stegmaier Kimberly, Raj Srilakshmi M., Maloney Katherine N., Clardy Jon, Hahn William C., Chiosis Gabriela, and Golub Todd R. Cancer Cell, 2006/10//, Volume 10, Issue 4, p.321 - 30, (2006) Read More / View Supplemental Materials
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Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistanceWei, Guo, Twomey David, Lamb Justin, Schlis Krysta, Agarwal Jyoti, Stam Ronald W., Opferman Joseph T., Sallan Stephen E., den Boer Monique L., Pieters Rob, Golub Todd R., and Armstrong Scott A. Cancer Cell, 2006/10//, Volume 10, Issue 4, p.331 - 42, (2006) Read More / View Supplemental Materials
Abstract
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and diseaseLamb, Justin, Crawford Emily D., Peck David, Modell Joshua W., Blat Irene C., Wrobel Matthew J., Lerner Jim, Brunet Jean-Philippe, Subramanian Aravind, Ross Kenneth N., Reich Michael, Hieronymus Haley, Wei Guo, Armstrong Scott A., Haggarty Stephen J., and Clemons Pau Science (New York, N.Y.), 2006/09/29/, Volume 313, Issue 5795, p.1929 - 35, (2006) Read More / View Supplemental Materials
Abstract
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9Krivtsov, Andrei V., Twomey David, Feng Zhaohui, Stubbs Matthew C., Wang Yingzi, Faber Joerg, Levine Jason E., Wang Jing, Hahn William C., Gilliland Gary D., Golub Todd R., and Armstrong Scott A. Nature, 2006/08/17/, Volume 442, Issue 7104, p.818 - 22, (2006) Read More / View Supplemental Materials
Abstract
2005
Epstein-Barr-virus-encoded LMP2A induces primary epithelial cell migration and invasion: possible role in nasopharyngeal carcinoma metastasisPegtel, Dirk M., Subramanian Aravind, Sheen Tzung-Shiahn, Tsai Ching-Hwa, Golub Todd R., and Thorley-Lawson David A. Journal of Virology, 2005/12//, Volume 79, Issue 24, p.15430 - 42, (2005) Read More / View Supplemental Materials
Abstract
Allele-specific amplification in cancer revealed by SNP array analysisLaFramboise, Thomas, Weir Barbara A., Zhao Xiaojun, Beroukhim Rameen, Li Cheng, Harrington David, Sellers William R., and Meyerson Matthew PLoS Computational Biology, 2005/11//, Volume 1, Issue 6, p.e65 - e65, (2005) Read More / View Supplemental Materials
Abstract
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesSubramanian, Aravind, Tamayo Pablo, Mootha Vamsi K., Mukherjee Sayan, Ebert Benjamin L., Gillette Michael A., Paulovich Amanda, Pomeroy Scott L., Golub Todd R., Lander Eric S., and Mesirov Jill P. Proceedings of the National Academy of Sciences of the United States of America, 2005/10/25/, Volume 102, Issue 43, p.15545 - 50, (2005) Read More / View Supplemental Materials
Abstract
NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypesFeuerhake, Friedrich, Kutok Jeffery L., Monti Stefano, Chen Wen, LaCasce Ann S., Cattoretti Giorgio, Kurtin Paul, Pinkus Geraldine S., de Leval Laurence, Harris Nancy L., Savage Kerry J., Neuberg Donna, Habermann Thomas M., Dalla-Favera Riccardo, Golub Todd R., and A Blood, 2005/08/15/, Volume 106, Issue 4, p.1392 - 9, (2005) Read More / View Supplemental Materials
Abstract
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanomaGarraway, Levi A., Widlund Hans R., Rubin Mark A., Getz Gad, Berger Aaron J., Ramaswamy Sridhar, Beroukhim Rameen, Milner Danny A., Granter Scott R., Du Jinyan, Lee Charles, Wagner Stephan N., Li Cheng, Golub Todd R., Rimm David L., Meyerson Matthew L., and Fisher David Nature, 2005/07/07/, Volume 436, Issue 7047, p.117 - 22, (2005) Read More / View Supplemental Materials
Abstract
Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysisZhao, Xiaojun, Weir Barbara A., LaFramboise Thomas, Lin Ming, Beroukhim Rameen, Garraway Levi, Beheshti Javad, Lee Jeffrey C., Naoki Katsuhiko, Richards William G., Sugarbaker David, Chen Fei, Rubin Mark A., and J Cancer Research, 2005/07/01/, Volume 65, Issue 13, p.5561 - 70, (2005) Read More / View Supplemental Materials
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An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarrayEbert, Benjamin L., Lee Michele M., Pretz Jennifer L., Subramanian Aravind, Mak Raymond, Golub Todd R., and Sieff Colin A. Blood, 2005/06/15/, Volume 105, Issue 12, p.4620 - 6, (2005) Read More / View Supplemental Materials
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2004
The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1Coletta, Ricardo D., Christensen Kimberly, Reichenberger Kelly J., Lamb Justin, Micomonaco Damian, Huang Lili, Wolf Douglas M., and M Proceedings of the National Academy of Sciences of the United States of America, 2004/04/27/, Volume 101, Issue 17, p.6478 - 83, (2004) Read More / View Supplemental Materials
Abstract
Genome coverage and sequence fidelity of phi29 polymerase-based multiple strand displacement whole genome amplificationPaez, Guillermo J., Lin Ming, Beroukhim Rameen, Lee Jeffrey C., Zhao Xiaojun, Richter Daniel J., Gabriel Stacey, Herman Paula, Sasaki Hidefumi, Altshuler David, Li Cheng, Meyerson Matthew, and Sellers William R. Nucleic Acids Research, 2004///, Volume 32, Issue 9, p.e71 - e71, (2004) Read More / View Supplemental Materials
Abstract
2003
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondriaMootha, Vamsi K., Bunkenborg Jakob, Olsen Jesper V., Hjerrild Majbrit, Wisniewski Jacek R., Stahl Erich, Bolouri Marjan S., Ray Heta N., Sihag Smita, Kamal Michael, Patterson Nick, Lander Eric S., and Mann Matthias Cell, 2003/11/26/, Volume 115, Issue 5, p.629 - 40, (2003) Read More / View Supplemental Materials
Abstract
2001
c-Myc is a critical target for c/EBPalpha in granulopoiesisJohansen, L. M., Iwama A., Lodie T. A., Sasaki K., Felsher D. W., Golub T. R., and Tenen D. G. Molecular and Cellular Biology, 2001/06//, Volume 21, Issue 11, p.3789 - 806, (2001) Read More / View Supplemental Materials
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2000
Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesionColler, H. A., Grandori C., Tamayo P., Colbert T., Lander E. S., Eisenman R. N., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2000/03/28/, Volume 97, Issue 7, p.3260 - 5, (2000) Read More / View Supplemental Materials
Abstract
1999
Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genesFambrough, D., McClure K., Kazlauskas A., and Lander E. S. Cell, 1999/06/11/, Volume 97, Issue 6, p.727 - 41, (1999) Read More / View Supplemental Materials
Abstract
  • Showing 1-26 of 26 Results