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2008
Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiationHahn, Cynthia K., Ross Kenneth N., Warrington Ian M., Mazitschek Ralph, Kanegai Cindy M., Wright Renee D., Kung Andrew L., Golub Todd R., and Stegmaier Kimberly Proceedings of the National Academy of Sciences of the United States of America, 2008/07/15/, Volume 105, Issue 28, p.9751 - 6, (2008) Read More / View Supplemental Materials
Abstract
15-Hydroxyprostaglandin dehydrogenase is a target of hepatocyte nuclear factor 3beta and a tumor suppressor in lung cancerHuang, Guosheng, Eisenberg Rosana, Yan Min, Monti Stefano, Lawrence Earl, Fu Pingfu, Walbroehl Jaclyn, and L Cancer Research, 2008/07/01/, Volume 68, Issue 13, p.5040 - 8, (2008) Read More / View Supplemental Materials
Abstract
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancerSetlur, Sunita R., Mertz Kirsten D., Hoshida Yujin, Demichelis Francesca, Lupien Mathieu, Perner Sven, Sboner Andrea, Pawitan Yudi, and Andr Journal of the National Cancer Institute, 2008/06/04/, Volume 100, Issue 11, p.815 - 25, (2008) Read More / View Supplemental Materials
Abstract
Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cellsMishra, Pravin J., Mishra Prasun J., Humeniuk Rita, Medina Daniel J., Alexe Gabriela, Mesirov Jill P., Ganesan Sridhar, Glod John W., and Banerjee Debabrata Cancer Research, 2008/06/01/, Volume 68, Issue 11, p.4331 - 9, (2008) Read More / View Supplemental Materials
Abstract
MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitorsLu, Jun, Guo Shangqin, Ebert Benjamin L., Zhang Hao, Peng Xiao, Bosco Jocelyn, Pretz Jennifer, Schlanger Rita, Wang Judy Y., Mak Raymond H., Dombkowski David M., Preffer Frederic I., Scadden David T., and Golub Todd R. Developmental Cell, 2008/06//, Volume 14, Issue 6, p.843 - 53, (2008) Read More / View Supplemental Materials
Abstract
Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastasesXu, Lei, Shen Steven S., Hoshida Yujin, Subramanian Aravind, Ross Ken, Brunet Jean-Philippe, Wagner Stephan N., Ramaswamy Sridhar, Mesirov Jill P., and Hynes Richard O. Molecular Cancer Research: MCR, 2008/05//, Volume 6, Issue 5, p.760 - 9, (2008) Read More / View Supplemental Materials
Abstract
SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphomaChen, Linfeng, Monti Stefano, Juszczynski Przemyslaw, Daley John, Chen Wen, Witzig Thomas E., Habermann Thomas M., Kutok Jeffery L., and Shipp Margaret A. Blood, 2008/02/15/, Volume 111, Issue 4, p.2230 - 7, (2008) Read More / View Supplemental Materials
Abstract
An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndromeEbert, Benjamin L., Galili Naomi, Tamayo Pablo, Bosco Jocelyn, Mak Raymond, Pretz Jennifer, Tanguturi Shyam, Ladd-Acosta Christine, Stone Richard, Golub Todd R., and Raza Azra PLoS Medicine, 2008/02//, Volume 5, Issue 2, p.e35 - e35, (2008) Read More / View Supplemental Materials
Abstract
An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndromeEbert, Benjamin L., Galili Naomi, Tamayo Pablo, Bosco Jocelyn, Mak Raymond, Pretz Jennifer, Tanguturi Shyam, Ladd-Acosta Christine, Stone Richard, Golub Todd R., and Raza Azra PLoS Medicine, 2008/02//, Volume 5, Issue 2, p.e35 - e35, (2008) Read More / View Supplemental Materials
Abstract
Cancer: hay in a haystackShannon, Kevin M., and Le Beau Michelle M. Nature, 2008/01/17/, Volume 451, Issue 7176, p.252 - 3, (2008) Read More / View Supplemental Materials
Identification of RPS14 as a 5q- syndrome gene by RNA interference screenEbert, Benjamin L., Pretz Jennifer, Bosco Jocelyn, Chang Cindy Y., Tamayo Pablo, Galili Naomi, Raza Azra, Root David E., Attar Eyal, Ellis Steven R., and Golub Todd R. Nature, 2008/01/17/, Volume 451, Issue 7176, p.335 - 9, (2008) Read More / View Supplemental Materials
Abstract
Integrative analysis reveals 53BP1 copy loss and decreased expression in a subset of human diffuse large B-cell lymphomasTakeyama, K., Monti S., Manis J. P., Cin Dal P., Getz G., Beroukhim R., Dutt S., Aster J. C., Alt F. W., Golub T. R., and Shipp M. A. Oncogene, 2008/01/10/, Volume 27, Issue 3, p.318 - 22, (2008) Read More / View Supplemental Materials
Abstract
2007
Assessing the significance of chromosomal aberrations in cancer: methodology and application to gliomaBeroukhim, Rameen, Getz Gad, Nghiemphu Leia, Barretina Jordi, Hsueh Teli, Linhart David, Vivanco Igor, Lee Jeffrey C., Huang Julie H., Alexander Sethu, Du Jinyan, Kau Tweeny, Thomas Roman K., Shah Kinjal, Soto Horacio, Perner Sven, Prensner John, and Debiasi Ralp Proceedings of the National Academy of Sciences of the United States of America, 2007/12/11/, Volume 104, Issue 50, p.20007 - 12, (2007) Read More / View Supplemental Materials
Abstract
Characterizing the cancer genome in lung adenocarcinomaWeir, Barbara A., Woo Michele S., Getz Gad, Perner Sven, Ding Li, Beroukhim Rameen, Lin William M., Province Michael A., Kraja Aldi, Johnson Laura A., Shah Kinjal, Sato Mitsuo, Thomas Roman K., Barletta Justine A., Borecki Ingrid B., Broderick Stephen, and Chang Andre Nature, 2007/12/06/, Volume 450, Issue 7171, p.893 - 8, (2007) Read More / View Supplemental Materials
Abstract
High expression of lymphocyte-associated genes in node-negative HER2+ breast cancers correlates with lower recurrence ratesAlexe, Gabriela, Dalgin Gul S., Scanfeld Daniel, Tamayo Pablo, Mesirov Jill P., DeLisi Charles, Harris Lyndsay, Barnard Nicola, Martel Maritza, Levine Arnold J., Ganesan Shridar, and Bhanot Gyan Cancer Research, 2007/11/15/, Volume 67, Issue 22, p.10669 - 76, (2007) Read More / View Supplemental Materials
Abstract
Lesional gene expression profiling in cutaneous T-cell lymphoma reveals natural clusters associated with disease outcomeShin, Jessica, Monti Stefano, Aires Daniel J., Duvic Madeleine, Golub Todd, Jones David A., and Kupper Thomas S. Blood, 2007/10/15/, Volume 110, Issue 8, p.3015 - 27, (2007) Read More / View Supplemental Materials
Abstract
MicroRNAs and cancerCowland, Jack B., Hother Christoffer, and Gr APMIS: Acta Pathologica, Microbiologica, Et Immunologica Scandinavica, 2007/10//, Volume 115, Issue 10, p.1090 - 106, (2007) Read More / View Supplemental Materials
Abstract
The AP1-dependent secretion of galectin-1 by Reed Sternberg cells fosters immune privilege in classical Hodgkin lymphomaJuszczynski, Przemyslaw, Ouyang Jing, Monti Stefano, Rodig Scott J., Takeyama Kunihiko, Abramson Jeremy, Chen Wen, Kutok Jeffery L., Rabinovich Gabriel A., and Shipp Margaret A. Proceedings of the National Academy of Sciences of the United States of America, 2007/08/07/, Volume 104, Issue 32, p.13134 - 9, (2007) Read More / View Supplemental Materials
Abstract
TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohortDemichelis, F., Fall K., Perner S., and Andr Oncogene, 2007/07/05/, Volume 26, Issue 31, p.4596 - 9, (2007) Read More / View Supplemental Materials
Abstract
Impaired microRNA processing enhances cellular transformation and tumorigenesisKumar, Madhu S., Lu Jun, Mercer Kim L., Golub Todd R., and Jacks Tyler Nature Genetics, 2007/05//, Volume 39, Issue 5, p.673 - 7, (2007) Read More / View Supplemental Materials
Abstract
Metagene projection for cross-platform, cross-species characterization of global transcriptional statesTamayo, Pablo, Scanfeld Daniel, Ebert Benjamin L., Gillette Michael A., Roberts Charles W. M., and Mesirov Jill P. Proceedings of the National Academy of Sciences of the United States of America, 2007/04/03/, Volume 104, Issue 14, p.5959 - 64, (2007) Read More / View Supplemental Materials
Abstract
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcomaStegmaier, Kimberly, Wong Jenny S., Ross Kenneth N., Chow Kwan T., Peck David, Wright Renee D., Lessnick Stephen L., Kung Andrew L., and Golub Todd R. PLoS Medicine, 2007/04//, Volume 4, Issue 4, p.e122 - e122, (2007) Read More / View Supplemental Materials
Abstract
Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomasPolo, Jose M., Juszczynski Przemyslaw, Monti Stefano, Cerchietti Leandro, Ye Kenny, Greally John M., Shipp Margaret, and Melnick Ari Proceedings of the National Academy of Sciences of the United States of America, 2007/02/27/, Volume 104, Issue 9, p.3207 - 12, (2007) Read More / View Supplemental Materials
Abstract
Portraits of breast cancer progressionDalgin, Gul S., Alexe Gabriela, Scanfeld Daniel, Tamayo Pablo, Mesirov Jill P., Ganesan Shridar, DeLisi Charles, and Bhanot Gyan BMC Bioinformatics, 2007///, Volume 8, p.291 - 291, (2007) Read More / View Supplemental Materials
Abstract
Subclass mapping: identifying common subtypes in independent disease data setsHoshida, Yujin, Brunet Jean-Philippe, Tamayo Pablo, Golub Todd R., and Mesirov Jill P. PLoS ONE, 2007///, Volume 2, Issue 11, p.e1195 - e1195, (2007) Read More / View Supplemental Materials
Abstract
2006
Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signalingKobayashi, Susumu, Shimamura Takeshi, Monti Stefano, Steidl Ulrich, Hetherington Christopher J., Lowell April M., Golub Todd, Meyerson Matthew, Tenen Daniel G., Shapiro Geoffrey I., and Halmos Bal Cancer Research, 2006/12/01/, Volume 66, Issue 23, p.11389 - 98, (2006) Read More / View Supplemental Materials
Abstract
Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohortsHayes, Neil D., Monti Stefano, Parmigiani Giovanni, Gilks Blake C., Naoki Katsuhiko, Bhattacharjee Arindam, Socinski Mark A., Perou Charles, and Meyerson Matthew Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 2006/11/01/, Volume 24, Issue 31, p.5079 - 90, (2006) Read More / View Supplemental Materials
Abstract
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulatorsHieronymus, Haley, Lamb Justin, Ross Kenneth N., Peng Xiao P., Clement Cristina, Rodina Anna, Nieto Maria, Du Jinyan, Stegmaier Kimberly, Raj Srilakshmi M., Maloney Katherine N., Clardy Jon, Hahn William C., Chiosis Gabriela, and Golub Todd R. Cancer Cell, 2006/10//, Volume 10, Issue 4, p.321 - 30, (2006) Read More / View Supplemental Materials
Abstract
Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistanceWei, Guo, Twomey David, Lamb Justin, Schlis Krysta, Agarwal Jyoti, Stam Ronald W., Opferman Joseph T., Sallan Stephen E., den Boer Monique L., Pieters Rob, Golub Todd R., and Armstrong Scott A. Cancer Cell, 2006/10//, Volume 10, Issue 4, p.331 - 42, (2006) Read More / View Supplemental Materials
Abstract
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and diseaseLamb, Justin, Crawford Emily D., Peck David, Modell Joshua W., Blat Irene C., Wrobel Matthew J., Lerner Jim, Brunet Jean-Philippe, Subramanian Aravind, Ross Kenneth N., Reich Michael, Hieronymus Haley, Wei Guo, Armstrong Scott A., Haggarty Stephen J., and Clemons Pau Science (New York, N.Y.), 2006/09/29/, Volume 313, Issue 5795, p.1929 - 35, (2006) Read More / View Supplemental Materials
Abstract
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9Krivtsov, Andrei V., Twomey David, Feng Zhaohui, Stubbs Matthew C., Wang Yingzi, Faber Joerg, Levine Jason E., Wang Jing, Hahn William C., Gilliland Gary D., Golub Todd R., and Armstrong Scott A. Nature, 2006/08/17/, Volume 442, Issue 7104, p.818 - 22, (2006) Read More / View Supplemental Materials
Abstract
Comparative gene marker selection suiteGould, Joshua, Getz Gad, Monti Stefano, Reich Michael, and Mesirov Jill P. Bioinformatics (Oxford, England), 2006/08/01/, Volume 22, Issue 15, p.1924 - 5, (2006) Read More / View Supplemental Materials
Abstract
Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcomaSmith, Richard, Owen Leah A., Trem Deborah J., Wong Jenny S., Whangbo Jennifer S., Golub Todd R., and Lessnick Stephen L. Cancer Cell, 2006/05//, Volume 9, Issue 5, p.405 - 16, (2006) Read More / View Supplemental Materials
Abstract
GenePattern 2.0Reich, Michael, Liefeld Ted, Gould Joshua, Lerner Jim, Tamayo Pablo, and Mesirov Jill P. Nature Genetics, 2006/05//, Volume 38, Issue 5, p.500 - 1, (2006) Read More / View Supplemental Materials
Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profilingBourquin, Jean-Pierre, Subramanian Aravind, Langebrake Claudia, Reinhardt Dirk, Bernard Olivier, Ballerini Paola, and Baruchel Andr Proceedings of the National Academy of Sciences of the United States of America, 2006/02/28/, Volume 103, Issue 9, p.3339 - 44, (2006) Read More / View Supplemental Materials
Abstract
2005
Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformationIsakoff, Michael S., Sansam Courtney G., Tamayo Pablo, Subramanian Aravind, Evans Julia A., Fillmore Christine M., Wang Xi, Biegel Jaclyn A., Pomeroy Scott L., Mesirov Jill P., and Roberts Charles W. M. Proceedings of the National Academy of Sciences of the United States of America, 2005/12/06/, Volume 102, Issue 49, p.17745 - 50, (2005) Read More / View Supplemental Materials
Abstract
Epstein-Barr-virus-encoded LMP2A induces primary epithelial cell migration and invasion: possible role in nasopharyngeal carcinoma metastasisPegtel, Dirk M., Subramanian Aravind, Sheen Tzung-Shiahn, Tsai Ching-Hwa, Golub Todd R., and Thorley-Lawson David A. Journal of Virology, 2005/12//, Volume 79, Issue 24, p.15430 - 42, (2005) Read More / View Supplemental Materials
Abstract
The impact of Life Science Identifier on informatics dataMartin, Sean, Hohman Moses M., and Liefeld Ted Drug Discovery Today, 2005/11/15/, Volume 10, Issue 22, p.1566 - 72, (2005) Read More / View Supplemental Materials
Abstract
Allele-specific amplification in cancer revealed by SNP array analysisLaFramboise, Thomas, Weir Barbara A., Zhao Xiaojun, Beroukhim Rameen, Li Cheng, Harrington David, Sellers William R., and Meyerson Matthew PLoS Computational Biology, 2005/11//, Volume 1, Issue 6, p.e65 - e65, (2005) Read More / View Supplemental Materials
Abstract
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesSubramanian, Aravind, Tamayo Pablo, Mootha Vamsi K., Mukherjee Sayan, Ebert Benjamin L., Gillette Michael A., Paulovich Amanda, Pomeroy Scott L., Golub Todd R., Lander Eric S., and Mesirov Jill P. Proceedings of the National Academy of Sciences of the United States of America, 2005/10/25/, Volume 102, Issue 43, p.15545 - 50, (2005) Read More / View Supplemental Materials
Abstract
Gefitinib induces myeloid differentiation of acute myeloid leukemiaStegmaier, Kimberly, Corsello Steven M., Ross Kenneth N., Wong Jenny S., Deangelo Daniel J., and Golub Todd R. Blood, 2005/10/15/, Volume 106, Issue 8, p.2841 - 8, (2005) Read More / View Supplemental Materials
Abstract
GeneCruiser: a web service for the annotation of microarray dataLiefeld, Ted, Reich Michael, Gould Joshua, Zhang Peili, Tamayo Pablo, and Mesirov Jill P. Bioinformatics (Oxford, England), 2005/09/15/, Volume 21, Issue 18, p.3681 - 2, (2005) Read More / View Supplemental Materials
Abstract
A zebrafish bmyb mutation causes genome instability and increased cancer susceptibilityShepard, Jennifer L., Amatruda James F., Stern Howard M., Subramanian Aravind, Finkelstein David, Ziai James, Finley Rose K., Pfaff Kathleen L., Hersey Candace, Zhou Yi, Barut Bruce, Freedman Matthew, Lee Charles, Spitsbergen Jan, Neuberg Donna, and Weber Gerhard Proceedings of the National Academy of Sciences of the United States of America, 2005/09/13/, Volume 102, Issue 37, p.13194 - 9, (2005) Read More / View Supplemental Materials
Abstract
NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypesFeuerhake, Friedrich, Kutok Jeffery L., Monti Stefano, Chen Wen, LaCasce Ann S., Cattoretti Giorgio, Kurtin Paul, Pinkus Geraldine S., de Leval Laurence, Harris Nancy L., Savage Kerry J., Neuberg Donna, Habermann Thomas M., Dalla-Favera Riccardo, Golub Todd R., and A Blood, 2005/08/15/, Volume 106, Issue 4, p.1392 - 9, (2005) Read More / View Supplemental Materials
Abstract
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanomaGarraway, Levi A., Widlund Hans R., Rubin Mark A., Getz Gad, Berger Aaron J., Ramaswamy Sridhar, Beroukhim Rameen, Milner Danny A., Granter Scott R., Du Jinyan, Lee Charles, Wagner Stephan N., Li Cheng, Golub Todd R., Rimm David L., Meyerson Matthew L., and Fisher David Nature, 2005/07/07/, Volume 436, Issue 7047, p.117 - 22, (2005) Read More / View Supplemental Materials
Abstract
Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysisZhao, Xiaojun, Weir Barbara A., LaFramboise Thomas, Lin Ming, Beroukhim Rameen, Garraway Levi, Beheshti Javad, Lee Jeffrey C., Naoki Katsuhiko, Richards William G., Sugarbaker David, Chen Fei, Rubin Mark A., and J Cancer Research, 2005/07/01/, Volume 65, Issue 13, p.5561 - 70, (2005) Read More / View Supplemental Materials
Abstract
An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarrayEbert, Benjamin L., Lee Michele M., Pretz Jennifer L., Subramanian Aravind, Mak Raymond, Golub Todd R., and Sieff Colin A. Blood, 2005/06/15/, Volume 105, Issue 12, p.4620 - 6, (2005) Read More / View Supplemental Materials
Abstract
MicroRNA expression profiles classify human cancersLu, Jun, Getz Gad, Miska Eric A., Alvarez-Saavedra Ezequiel, Lamb Justin, Peck David, Sweet-Cordero Alejandro, Ebert Benjamin L., Mak Raymond H., Ferrando Adolfo A., Downing James R., Jacks Tyler, Horvitz Robert H., and Golub Todd R. Nature, 2005/06/09/, Volume 435, Issue 7043, p.834 - 8, (2005) Read More / View Supplemental Materials
Abstract
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammalsXie, Xiaohui, Lu Jun, Kulbokas E. J., Golub Todd R., Mootha Vamsi, Lindblad-Toh Kerstin, Lander Eric S., and Kellis Manolis Nature, 2005/03/17/, Volume 434, Issue 7031, p.338 - 45, (2005) Read More / View Supplemental Materials
Abstract
Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory responseMonti, Stefano, Savage Kerry J., Kutok Jeffery L., Feuerhake Friedrich, Kurtin Paul, Mihm Martin, Wu Bingyan, Pasqualucci Laura, Neuberg Donna, Aguiar Ricardo C. T., Dal Cin Paola, Ladd Christine, Pinkus Geraldine S., Salles Gilles, Harris Nancy Lee, and Dalla-Fave Blood, 2005/03/01/, Volume 105, Issue 5, p.1851 - 61, (2005) Read More / View Supplemental Materials
Abstract
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysisSweet-Cordero, Alejandro, Mukherjee Sayan, Subramanian Aravind, You Han, Roix Jeffrey J., Ladd-Acosta Christine, Mesirov Jill, Golub Todd R., and Jacks Tyler Nature Genetics, 2005/01//, Volume 37, Issue 1, p.48 - 55, (2005) Read More / View Supplemental Materials
Abstract
2004
Genomic approaches to hematologic malignanciesEbert, Benjamin L., and Golub Todd R. Blood, 2004/08/15/, Volume 104, Issue 4, p.923 - 32, (2004) Read More / View Supplemental Materials
Abstract
GeneCluster 2.0: an advanced toolset for bioarray analysisReich, M., Ohm K., Angelo M., Tamayo P., and Mesirov J. P. Bioinformatics (Oxford, England), 2004/07/22/, Volume 20, Issue 11, p.1797 - 8, (2004) Read More / View Supplemental Materials
Abstract
Molecular characterization of the tumor microenvironment in breast cancerAllinen, Minna, Beroukhim Rameen, Cai Li, Brennan Cameron, Lahti-Domenici Jaana, Huang Haiyan, Porter Dale, Hu Min, Chin Lynda, Richardson Andrea, Schnitt Stuart, Sellers William R., and Polyak Kornelia Cancer Cell, 2004/07//, Volume 6, Issue 1, p.17 - 32, (2004) Read More / View Supplemental Materials
Abstract
A transcriptional profiling study of CCAAT/enhancer binding protein targets identifies hepatocyte nuclear factor 3 beta as a novel tumor suppressor in lung cancerHalmos, Balazs, and Bass Cancer Research, 2004/06/15/, Volume 64, Issue 12, p.4137 - 47, (2004) Read More / View Supplemental Materials
Abstract
dChipSNP: significance curve and clustering of SNP-array-based loss-of-heterozygosity dataLin, Ming, Wei Lee-Jen, Sellers William R., Lieberfarb Marshall, Wong Wing Hung, and Li Cheng Bioinformatics (Oxford, England), 2004/05/22/, Volume 20, Issue 8, p.1233 - 40, (2004) Read More / View Supplemental Materials
Abstract
An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arraysZhao, Xiaojun, Li Cheng, Paez Guillermo J., Chin Koei, and J Cancer Research, 2004/05/01/, Volume 64, Issue 9, p.3060 - 71, (2004) Read More / View Supplemental Materials
Abstract
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscleMootha, Vamsi K., Handschin Christoph, Arlow Dan, Xie Xiaohui, St Pierre Julie, Sihag Smita, Yang Wenli, Altshuler David, Puigserver Pere, Patterson Nick, Willy Patricia J., Schulman Ira G., Heyman Richard A., Lander Eric S., and Spiegelman Bruce M. Proceedings of the National Academy of Sciences of the United States of America, 2004/04/27/, Volume 101, Issue 17, p.6570 - 5, (2004) Read More / View Supplemental Materials
Abstract
The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1Coletta, Ricardo D., Christensen Kimberly, Reichenberger Kelly J., Lamb Justin, Micomonaco Damian, Huang Lili, Wolf Douglas M., and M Proceedings of the National Academy of Sciences of the United States of America, 2004/04/27/, Volume 101, Issue 17, p.6478 - 83, (2004) Read More / View Supplemental Materials
Abstract
Metagenes and molecular pattern discovery using matrix factorizationBrunet, Jean-Philippe, Tamayo Pablo, Golub Todd R., and Mesirov Jill P. Proceedings of the National Academy of Sciences of the United States of America, 2004/03/23/, Volume 101, Issue 12, p.4164 - 9, (2004) Read More / View Supplemental Materials
Abstract
Combining gene expression profiles and clinical parameters for risk stratification in medulloblastomasFernandez-Teijeiro, Ana, Betensky Rebecca A., Sturla Lisa M., Kim John Y. H., Tamayo Pablo, and Pomeroy Scott L. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 2004/03/15/, Volume 22, Issue 6, p.994 - 8, (2004) Read More / View Supplemental Materials
Abstract
Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiationStegmaier, Kimberly, Ross Kenneth N., Colavito Sierra A., O'Malley Shawn, Stockwell Brent R., and Golub Todd R. Nature Genetics, 2004/03//, Volume 36, Issue 3, p.257 - 63, (2004) Read More / View Supplemental Materials
Abstract
Globally distributed object identification for biological knowledgebasesClark, Tim, Martin Sean, and Liefeld Ted Briefings in Bioinformatics, 2004/03//, Volume 5, Issue 1, p.59 - 70, (2004) Read More / View Supplemental Materials
Abstract
Loss of heterozygosity and its correlation with expression profiles in subclasses of invasive breast cancersWang, Zhigang C., Lin Ming, Wei Lee-Jen, Li Cheng, Miron Alexander, Lodeiro Gabriella, Harris Lyndsay, Ramaswamy Sridhar, Tanenbaum David M., Meyerson Matthew, Iglehart James D., and Richardson Andrea Cancer Research, 2004/01/01/, Volume 64, Issue 1, p.64 - 71, (2004) Read More / View Supplemental Materials
Abstract
Genome coverage and sequence fidelity of phi29 polymerase-based multiple strand displacement whole genome amplificationPaez, Guillermo J., Lin Ming, Beroukhim Rameen, Lee Jeffrey C., Zhao Xiaojun, Richter Daniel J., Gabriel Stacey, Herman Paula, Sasaki Hidefumi, Altshuler David, Li Cheng, Meyerson Matthew, and Sellers William R. Nucleic Acids Research, 2004///, Volume 32, Issue 9, p.e71 - e71, (2004) Read More / View Supplemental Materials
Abstract
2003
The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphomaSavage, Kerry J., Monti Stefano, Kutok Jeffery L., Cattoretti Giorgio, Neuberg Donna, de Leval Laurence, Kurtin Paul, Dal Cin Paola, Ladd Christine, Feuerhake Friedrich, Aguiar Ricardo C. T., Li Sigui, Salles Gilles, Berger Francoise, Jing Wen, and Pinkus Geraldin Blood, 2003/12/01/, Volume 102, Issue 12, p.3871 - 9, (2003) Read More / View Supplemental Materials
Abstract
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondriaMootha, Vamsi K., Bunkenborg Jakob, Olsen Jesper V., Hjerrild Majbrit, Wisniewski Jacek R., Stahl Erich, Bolouri Marjan S., Ray Heta N., Sihag Smita, Kamal Michael, Patterson Nick, Lander Eric S., and Mann Matthias Cell, 2003/11/26/, Volume 115, Issue 5, p.629 - 40, (2003) Read More / View Supplemental Materials
Abstract
MLL-rearranged leukemias: insights from gene expression profilingArmstrong, Scott A., Golub Todd R., and Korsmeyer Stanley J. Seminars in Hematology, 2003/10//, Volume 40, Issue 4, p.268 - 73, (2003) Read More / View Supplemental Materials
Abstract
A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancerLamb, Justin, Ramaswamy Sridhar, Ford Heide L., Contreras Bernardo, Martinez Robert V., Kittrell Frances S., Zahnow Cynthia A., Patterson Nick, Golub Todd R., and Ewen Mark E. Cell, 2003/08/08/, Volume 114, Issue 3, p.323 - 34, (2003) Read More / View Supplemental Materials
Abstract
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetesMootha, Vamsi K., Lindgren Cecilia M., Eriksson Karl-Fredrik, Subramanian Aravind, Sihag Smita, Lehar Joseph, Puigserver Pere, Carlsson Emma, and Ridderstr Nature Genetics, 2003/07//, Volume 34, Issue 3, p.267 - 73, (2003) Read More / View Supplemental Materials
Abstract
DNA microarrays in breast cancer: the promise of personalised medicineRamaswamy, Sridhar, and Perou Charles M. Lancet, 2003/05/10/, Volume 361, Issue 9369, p.1576 - 7, (2003) Read More / View Supplemental Materials
Gene expression-based classification of malignant gliomas correlates better with survival than histological classificationNutt, Catherine L., Mani D. R., Betensky Rebecca A., Tamayo Pablo, Cairncross Gregory J., Ladd Christine, Pohl Ute, Hartmann Christian, McLaughlin Margaret E., Batchelor Tracy T., Black Peter M., von Deimling Andreas, Pomeroy Scott L., Golub Todd R., and Louis David N. Cancer Research, 2003/04/01/, Volume 63, Issue 7, p.1602 - 7, (2003) Read More / View Supplemental Materials
Abstract
Gene expression-based classification of malignant gliomas correlates better with survival than histological classificationNutt, Catherine L., Mani D. R., Betensky Rebecca A., Tamayo Pablo, Cairncross Gregory J., Ladd Christine, Pohl Ute, Hartmann Christian, McLaughlin Margaret E., Batchelor Tracy T., Black Peter M., von Deimling Andreas, Pomeroy Scott L., Golub Todd R., and Louis David N. Cancer Research, 2003/04/01/, Volume 63, Issue 7, p.1602 - 7, (2003) Read More / View Supplemental Materials
Abstract
Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomicsMootha, Vamsi K., Lepage Pierre, Miller Kathleen, Bunkenborg Jakob, Reich Michael, Hjerrild Majbrit, Delmonte Terrye, Villeneuve Amelie, Sladek Robert, Xu Fenghao, Mitchell Grant A., Morin Charles, Mann Matthias, Hudson Thomas J., Robinson Brian, and Rioux John D. Proceedings of the National Academy of Sciences of the United States of America, 2003/01/21/, Volume 100, Issue 2, p.605 - 10, (2003) Read More / View Supplemental Materials
Abstract
A molecular signature of metastasis in primary solid tumorsRamaswamy, Sridhar, Ross Ken N., Lander Eric S., and Golub Todd R. Nature Genetics, 2003/01//, Volume 33, Issue 1, p.49 - 54, (2003) Read More / View Supplemental Materials
Abstract
Estimating dataset size requirements for classifying DNA microarray dataMukherjee, Sayan, Tamayo Pablo, Rogers Simon, Rifkin Ryan, Engle Anna, Campbell Colin, Golub Todd R., and Mesirov Jill P. Journal of Computational Biology: A Journal of Computational Molecular Cell Biology, 2003///, Volume 10, Issue 2, p.119 - 42, (2003) Read More / View Supplemental Materials
Abstract
2002
Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cellsChen, Chang-Zheng, Li Min, de Graaf David, Monti Stefano, and G Proceedings of the National Academy of Sciences of the United States of America, 2002/11/26/, Volume 99, Issue 24, p.15468 - 73, (2002) Read More / View Supplemental Materials
Abstract
The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblastsLessnick, Stephen L., Dacwag Caroline S., and Golub Todd R. Cancer Cell, 2002/05//, Volume 1, Issue 4, p.393 - 401, (2002) Read More / View Supplemental Materials
Abstract
DNA microarrays in clinical oncologyRamaswamy, Sridhar, and Golub Todd R. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 2002/04/01/, Volume 20, Issue 7, p.1932 - 41, (2002) Read More / View Supplemental Materials
Abstract
Gene expression correlates of clinical prostate cancer behaviorSingh, Dinesh, Febbo Phillip G., Ross Kenneth, Jackson Donald G., Manola Judith, Ladd Christine, Tamayo Pablo, Renshaw Andrew A., D'Amico Anthony V., Richie Jerome P., Lander Eric S., Loda Massimo, Kantoff Philip W., Golub Todd R., and Sellers William R. Cancer Cell, 2002/03//, Volume 1, Issue 2, p.203 - 9, (2002) Read More / View Supplemental Materials
Abstract
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemiaFerrando, Adolfo A., Neuberg Donna S., Staunton Jane, Loh Mignon L., Huard Christine, Raimondi Susana C., Behm Fred G., Pui Ching Hon, Downing James R., Gilliland Gary D., Lander Eric S., Golub Todd R., and Look Thomas A. Cancer Cell, 2002/02//, Volume 1, Issue 1, p.75 - 87, (2002) Read More / View Supplemental Materials
Abstract
Prediction of central nervous system embryonal tumour outcome based on gene expressionPomeroy, Scott L., Tamayo Pablo, Gaasenbeek Michelle, Sturla Lisa M., Angelo Michael, McLaughlin Margaret E., Kim John Y. H., Goumnerova Liliana C., Black Peter M., Lau Ching, Allen Jeffrey C., Zagzag David, Olson James M., Curran Tom, Wetmore Cynthia, and Biegel Jacly Nature, 2002/01/24/, Volume 415, Issue 6870, p.436 - 42, (2002) Read More / View Supplemental Materials
Abstract
Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learningShipp, Margaret A., Ross Ken N., Tamayo Pablo, Weng Andrew P., Kutok Jeffery L., Aguiar Ricardo C. T., Gaasenbeek Michelle, Angelo Michael, Reich Michael, Pinkus Geraldine S., Ray Tane S., Koval Margaret A., Last Kim W., Norton Andrew, Lister Andrew T., and Mesirov Jill Nature Medicine, 2002/01//, Volume 8, Issue 1, p.68 - 74, (2002) Read More / View Supplemental Materials
Abstract
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemiaArmstrong, Scott A., Staunton Jane E., Silverman Lewis B., Pieters Rob, den Boer Monique L., Minden Mark D., Sallan Stephen E., Lander Eric S., Golub Todd R., and Korsmeyer Stanley J. Nature Genetics, 2002/01//, Volume 30, Issue 1, p.41 - 7, (2002) Read More / View Supplemental Materials
Abstract
A strategy for oligonucleotide microarray probe reductionAntipova, Alena A., Tamayo Pablo, and Golub Todd R. Genome Biology, 2002///, Volume 3, Issue 12, p.RESEARCH0073 - RESEARCH0073, (2002) Read More / View Supplemental Materials
Abstract
Molecular Determinants of Lymph Node Metastasis in Breast CancerXuegong Zhang, Catherine Gradek, Robert Gentleman Igor Leykin Stefano Monti Sridhar Ramaswamy Wing Wong Todd Golub H. R. J., and Richardson Andrea L., 05/01/2002, (2002) Read More / View Supplemental Materials
Abstract
2001
Multiclass cancer diagnosis using tumor gene expression signaturesRamaswamy, S., Tamayo P., Rifkin R., Mukherjee S., Yeang C. H., Angelo M., Ladd C., Reich M., Latulippe E., Mesirov J. P., Poggio T., Gerald W., Loda M., Lander E. S., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2001/12/18/, Volume 98, Issue 26, p.15149 - 54, (2001) Read More / View Supplemental Materials
Abstract
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclassesBhattacharjee, A., Richards W. G., Staunton J., Li C., Monti S., Vasa P., Ladd C., Beheshti J., Bueno R., Gillette M., Loda M., Weber G., Mark E. J., Lander E. S., Wong W., Johnson B. E., Golub T. R., Sugarbaker D. J., and Meyerson M. Proceedings of the National Academy of Sciences of the United States of America, 2001/11/20/, Volume 98, Issue 24, p.13790 - 5, (2001) Read More / View Supplemental Materials
Abstract
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclassesBhattacharjee, A., Richards W. G., Staunton J., Li C., Monti S., Vasa P., Ladd C., Beheshti J., Bueno R., Gillette M., Loda M., Weber G., Mark E. J., Lander E. S., Wong W., Johnson B. E., Golub T. R., Sugarbaker D. J., and Meyerson M. Proceedings of the National Academy of Sciences of the United States of America, 2001/11/20/, Volume 98, Issue 24, p.13790 - 5, (2001) Read More / View Supplemental Materials
Abstract
Chemosensitivity prediction by transcriptional profilingStaunton, J. E., Slonim D. K., Coller H. A., Tamayo P., Angelo M. J., Park J., Scherf U., Lee J. K., Reinhold W. O., Weinstein J. N., Mesirov J. P., Lander E. S., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2001/09/11/, Volume 98, Issue 19, p.10787 - 92, (2001) Read More / View Supplemental Materials
Abstract
c-Myc is a critical target for c/EBPalpha in granulopoiesisJohansen, L. M., Iwama A., Lodie T. A., Sasaki K., Felsher D. W., Golub T. R., and Tenen D. G. Molecular and Cellular Biology, 2001/06//, Volume 21, Issue 11, p.3789 - 806, (2001) Read More / View Supplemental Materials
Abstract
Genome-wide views of cancerGolub, T. R. The New England Journal of Medicine, 2001/02/22/, Volume 344, Issue 8, p.601 - 2, (2001) Read More / View Supplemental Materials
Genome-wide views of cancerGolub, T. R. The New England Journal of Medicine, 2001/02/22/, Volume 344, Issue 8, p.601 - 2, (2001) Read More / View Supplemental Materials
Molecular classification of multiple tumor typesYeang, C. H., Ramaswamy S., Tamayo P., Mukherjee S., Rifkin R. M., Angelo M., Reich M., Lander E., Mesirov J., and Golub T. Bioinformatics (Oxford, England), 2001///, Volume 17 Suppl 1, p.S316-22 - S316-22, (2001) Read More / View Supplemental Materials
Abstract
2000
Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arraysLindblad-Toh, K., Tanenbaum D. M., Daly M. J., Winchester E., Lui W. O., Villapakkam A., Stanton S. E., Larsson C., Hudson T. J., Johnson B. E., Lander E. S., and Meyerson M. Nature Biotechnology, 2000/09//, Volume 18, Issue 9, p.1001 - 5, (2000) Read More / View Supplemental Materials
Abstract
Genomic analysis of metastasis reveals an essential role for RhoCClark, E. A., Golub T. R., Lander E. S., and Hynes R. O. Nature, 2000/08/03/, Volume 406, Issue 6795, p.532 - 5, (2000) Read More / View Supplemental Materials
Abstract
Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesionColler, H. A., Grandori C., Tamayo P., Colbert T., Lander E. S., Eisenman R. N., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2000/03/28/, Volume 97, Issue 7, p.3260 - 5, (2000) Read More / View Supplemental Materials
Abstract
GENOMICS: Journey to the Center of BiologyLander, E. S., and Weinberg R. A. Science (New York, N.Y.), 2000/03/10/, Volume 287, Issue 5459, p.1777 - 82, (2000) Read More / View Supplemental Materials
1999
Molecular classification of cancer: class discovery and class prediction by gene expression monitoringGolub, T. R., Slonim D. K., Tamayo P., Huard C., Gaasenbeek M., Mesirov J. P., Coller H., Loh M. L., Downing J. R., Caligiuri M. A., Bloomfield C. D., and Lander E. S. Science (New York, N.Y.), 1999/10/15/, Volume 286, Issue 5439, p.531 - 7, (1999) Read More / View Supplemental Materials
Abstract
Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genesFambrough, D., McClure K., Kazlauskas A., and Lander E. S. Cell, 1999/06/11/, Volume 97, Issue 6, p.727 - 41, (1999) Read More / View Supplemental Materials
Abstract
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