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  • Showing 1-28 of 28 Results
2008
A mitochondrial protein compendium elucidates complex I disease biologyPagliarini, David J., Calvo Sarah E., Chang Betty, Sheth Sunil A., Vafai Scott B., Ong Shao-En, Walford Geoffrey A., Sugiana Canny, Boneh Avihu, Chen William K., Hill David E., Vidal Marc, Evans James G., Thorburn David R., Carr Steven A., and Mootha Vamsi K. Cell, 2008/07/11/, Volume 134, Issue 1, p.112 - 23, (2008) Read More / View Supplemental Materials
Abstract
15-Hydroxyprostaglandin dehydrogenase is a target of hepatocyte nuclear factor 3beta and a tumor suppressor in lung cancerHuang, Guosheng, Eisenberg Rosana, Yan Min, Monti Stefano, Lawrence Earl, Fu Pingfu, Walbroehl Jaclyn, and L Cancer Research, 2008/07/01/, Volume 68, Issue 13, p.5040 - 8, (2008) Read More / View Supplemental Materials
Abstract
MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitorsLu, Jun, Guo Shangqin, Ebert Benjamin L., Zhang Hao, Peng Xiao, Bosco Jocelyn, Pretz Jennifer, Schlanger Rita, Wang Judy Y., Mak Raymond H., Dombkowski David M., Preffer Frederic I., Scadden David T., and Golub Todd R. Developmental Cell, 2008/06//, Volume 14, Issue 6, p.843 - 53, (2008) Read More / View Supplemental Materials
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Cancer: hay in a haystackShannon, Kevin M., and Le Beau Michelle M. Nature, 2008/01/17/, Volume 451, Issue 7176, p.252 - 3, (2008) Read More / View Supplemental Materials
2007
Impaired microRNA processing enhances cellular transformation and tumorigenesisKumar, Madhu S., Lu Jun, Mercer Kim L., Golub Todd R., and Jacks Tyler Nature Genetics, 2007/05//, Volume 39, Issue 5, p.673 - 7, (2007) Read More / View Supplemental Materials
Abstract
Metagene projection for cross-platform, cross-species characterization of global transcriptional statesTamayo, Pablo, Scanfeld Daniel, Ebert Benjamin L., Gillette Michael A., Roberts Charles W. M., and Mesirov Jill P. Proceedings of the National Academy of Sciences of the United States of America, 2007/04/03/, Volume 104, Issue 14, p.5959 - 64, (2007) Read More / View Supplemental Materials
Abstract
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcomaStegmaier, Kimberly, Wong Jenny S., Ross Kenneth N., Chow Kwan T., Peck David, Wright Renee D., Lessnick Stephen L., Kung Andrew L., and Golub Todd R. PLoS Medicine, 2007/04//, Volume 4, Issue 4, p.e122 - e122, (2007) Read More / View Supplemental Materials
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2006
Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signalingKobayashi, Susumu, Shimamura Takeshi, Monti Stefano, Steidl Ulrich, Hetherington Christopher J., Lowell April M., Golub Todd, Meyerson Matthew, Tenen Daniel G., Shapiro Geoffrey I., and Halmos Bal Cancer Research, 2006/12/01/, Volume 66, Issue 23, p.11389 - 98, (2006) Read More / View Supplemental Materials
Abstract
Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistanceWei, Guo, Twomey David, Lamb Justin, Schlis Krysta, Agarwal Jyoti, Stam Ronald W., Opferman Joseph T., Sallan Stephen E., den Boer Monique L., Pieters Rob, Golub Todd R., and Armstrong Scott A. Cancer Cell, 2006/10//, Volume 10, Issue 4, p.331 - 42, (2006) Read More / View Supplemental Materials
Abstract
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9Krivtsov, Andrei V., Twomey David, Feng Zhaohui, Stubbs Matthew C., Wang Yingzi, Faber Joerg, Levine Jason E., Wang Jing, Hahn William C., Gilliland Gary D., Golub Todd R., and Armstrong Scott A. Nature, 2006/08/17/, Volume 442, Issue 7104, p.818 - 22, (2006) Read More / View Supplemental Materials
Abstract
Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcomaSmith, Richard, Owen Leah A., Trem Deborah J., Wong Jenny S., Whangbo Jennifer S., Golub Todd R., and Lessnick Stephen L. Cancer Cell, 2006/05//, Volume 9, Issue 5, p.405 - 16, (2006) Read More / View Supplemental Materials
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2005
Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformationIsakoff, Michael S., Sansam Courtney G., Tamayo Pablo, Subramanian Aravind, Evans Julia A., Fillmore Christine M., Wang Xi, Biegel Jaclyn A., Pomeroy Scott L., Mesirov Jill P., and Roberts Charles W. M. Proceedings of the National Academy of Sciences of the United States of America, 2005/12/06/, Volume 102, Issue 49, p.17745 - 50, (2005) Read More / View Supplemental Materials
Abstract
GeneCruiser: a web service for the annotation of microarray dataLiefeld, Ted, Reich Michael, Gould Joshua, Zhang Peili, Tamayo Pablo, and Mesirov Jill P. Bioinformatics (Oxford, England), 2005/09/15/, Volume 21, Issue 18, p.3681 - 2, (2005) Read More / View Supplemental Materials
Abstract
A zebrafish bmyb mutation causes genome instability and increased cancer susceptibilityShepard, Jennifer L., Amatruda James F., Stern Howard M., Subramanian Aravind, Finkelstein David, Ziai James, Finley Rose K., Pfaff Kathleen L., Hersey Candace, Zhou Yi, Barut Bruce, Freedman Matthew, Lee Charles, Spitsbergen Jan, Neuberg Donna, and Weber Gerhard Proceedings of the National Academy of Sciences of the United States of America, 2005/09/13/, Volume 102, Issue 37, p.13194 - 9, (2005) Read More / View Supplemental Materials
Abstract
MicroRNA expression profiles classify human cancersLu, Jun, Getz Gad, Miska Eric A., Alvarez-Saavedra Ezequiel, Lamb Justin, Peck David, Sweet-Cordero Alejandro, Ebert Benjamin L., Mak Raymond H., Ferrando Adolfo A., Downing James R., Jacks Tyler, Horvitz Robert H., and Golub Todd R. Nature, 2005/06/09/, Volume 435, Issue 7043, p.834 - 8, (2005) Read More / View Supplemental Materials
Abstract
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammalsXie, Xiaohui, Lu Jun, Kulbokas E. J., Golub Todd R., Mootha Vamsi, Lindblad-Toh Kerstin, Lander Eric S., and Kellis Manolis Nature, 2005/03/17/, Volume 434, Issue 7031, p.338 - 45, (2005) Read More / View Supplemental Materials
Abstract
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysisSweet-Cordero, Alejandro, Mukherjee Sayan, Subramanian Aravind, You Han, Roix Jeffrey J., Ladd-Acosta Christine, Mesirov Jill, Golub Todd R., and Jacks Tyler Nature Genetics, 2005/01//, Volume 37, Issue 1, p.48 - 55, (2005) Read More / View Supplemental Materials
Abstract
2004
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscleMootha, Vamsi K., Handschin Christoph, Arlow Dan, Xie Xiaohui, St Pierre Julie, Sihag Smita, Yang Wenli, Altshuler David, Puigserver Pere, Patterson Nick, Willy Patricia J., Schulman Ira G., Heyman Richard A., Lander Eric S., and Spiegelman Bruce M. Proceedings of the National Academy of Sciences of the United States of America, 2004/04/27/, Volume 101, Issue 17, p.6570 - 5, (2004) Read More / View Supplemental Materials
Abstract
The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1Coletta, Ricardo D., Christensen Kimberly, Reichenberger Kelly J., Lamb Justin, Micomonaco Damian, Huang Lili, Wolf Douglas M., and M Proceedings of the National Academy of Sciences of the United States of America, 2004/04/27/, Volume 101, Issue 17, p.6478 - 83, (2004) Read More / View Supplemental Materials
Abstract
Globally distributed object identification for biological knowledgebasesClark, Tim, Martin Sean, and Liefeld Ted Briefings in Bioinformatics, 2004/03//, Volume 5, Issue 1, p.59 - 70, (2004) Read More / View Supplemental Materials
Abstract
2003
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondriaMootha, Vamsi K., Bunkenborg Jakob, Olsen Jesper V., Hjerrild Majbrit, Wisniewski Jacek R., Stahl Erich, Bolouri Marjan S., Ray Heta N., Sihag Smita, Kamal Michael, Patterson Nick, Lander Eric S., and Mann Matthias Cell, 2003/11/26/, Volume 115, Issue 5, p.629 - 40, (2003) Read More / View Supplemental Materials
Abstract
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetesMootha, Vamsi K., Lindgren Cecilia M., Eriksson Karl-Fredrik, Subramanian Aravind, Sihag Smita, Lehar Joseph, Puigserver Pere, Carlsson Emma, and Ridderstr Nature Genetics, 2003/07//, Volume 34, Issue 3, p.267 - 73, (2003) Read More / View Supplemental Materials
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2002
Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cellsChen, Chang-Zheng, Li Min, de Graaf David, Monti Stefano, and G Proceedings of the National Academy of Sciences of the United States of America, 2002/11/26/, Volume 99, Issue 24, p.15468 - 73, (2002) Read More / View Supplemental Materials
Abstract
2001
c-Myc is a critical target for c/EBPalpha in granulopoiesisJohansen, L. M., Iwama A., Lodie T. A., Sasaki K., Felsher D. W., Golub T. R., and Tenen D. G. Molecular and Cellular Biology, 2001/06//, Volume 21, Issue 11, p.3789 - 806, (2001) Read More / View Supplemental Materials
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2000
Genomic analysis of metastasis reveals an essential role for RhoCClark, E. A., Golub T. R., Lander E. S., and Hynes R. O. Nature, 2000/08/03/, Volume 406, Issue 6795, p.532 - 5, (2000) Read More / View Supplemental Materials
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GENOMICS: Journey to the Center of BiologyLander, E. S., and Weinberg R. A. Science (New York, N.Y.), 2000/03/10/, Volume 287, Issue 5459, p.1777 - 82, (2000) Read More / View Supplemental Materials
1999
Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genesFambrough, D., McClure K., Kazlauskas A., and Lander E. S. Cell, 1999/06/11/, Volume 97, Issue 6, p.727 - 41, (1999) Read More / View Supplemental Materials
Abstract
Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiationTamayo, P., Slonim D., Mesirov J., Zhu Q., Kitareewan S., Dmitrovsky E., Lander E. S., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 1999/03/16/, Volume 96, Issue 6, p.2907 - 12, (1999) Read More / View Supplemental Materials
Abstract
  • Showing 1-28 of 28 Results