Recent Cancer Papers

Dynamic epigenetic regulation by menin during pancreatic islet tumor formation.Lin, W., Watanabe H., Peng S., Francis JM, Kaplan N., Pedamallu CS, Ramachandran A., Agoston A., Bass AJ, and Meyerson M. Molecular cancer research : MCR, 2015/04/01, Volume 13, Issue 4, p.689-98, (2015) Read More / View Supplemental Materials
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Precision medicine in breast cancer: genes, genomes, and the future of genomically driven treatments.Stover, DG, and Wagle N. Current oncology reports, 2015/04/01, Volume 17, Issue 4, p.15, (2015) Read More / View Supplemental Materials
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Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations.Ahronian, LG, Sennott EM, Van Allen EM, Wagle N., Kwak EL, Faris JE, Godfrey JT, Nishimura K., Lynch KD, Mermel CH, Lockerman EL, Kalsy A., Gurski JM Jr, Bahl S., Anderka K., Green LM, Lennon NJ, Huynh TG, Mino-Kenudson M., Getz G., et al. Cancer discovery, 2015/04/01, Volume 5, Issue 4, p.358-67, (2015) Read More / View Supplemental Materials
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The tumor virus landscape of AIDS-related lymphomas.Arvey, A., Ojesina A., Pedamallu CS, Ballon G., Jung J., Duke F., Leoncini L., De Falco G., Bressman E., Tam W., Chadburn A., Meyerson M., and Cesarman E. Blood, 2015/03/31, (2015) Read More / View Supplemental Materials
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DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.Chen, CW, Koche RP, Sinha AU, Deshpande AJ, Zhu N., Eng R., Doench JG, Xu H., Chu SH, Qi J., Wang X., Delaney C., Bernt KM, Root DE, Hahn WC, Bradner JE, and Armstrong SA Nature medicine, 2015/03/30, (2015) Read More / View Supplemental Materials
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PLZF, a Tumor Suppressor Genetically Lost in Metastatic Castration Resistant Prostate Cancer, is a Mediator of Resistance to Androgen Deprivation Therapy.Hsieh, CL, Botta G., Gao S., Li T., Van Allen EM, Treacy DJ, Cai C., He HH, Sweeney CJ, Brown M., Balk SP, Nelson PS, Garraway LA, and Kantoff PW Cancer research, 2015/03/25, (2015) Read More / View Supplemental Materials
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Inactivation of HDAC1 or HDAC2 induces gamma globin expression without altering cell cycle or proliferation.Esrick, EB, McConkey M., Lin K., Frisbee A., and Ebert BL American journal of hematology, 2015/03/23, (2015) Read More / View Supplemental Materials
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A genomic data viewer for iPad.Thorvaldsdóttir, H., Robinson JT, Turner D., and Mesirov J. P. Genome biology, 2015/02/26, Volume 16, p.46, (2015) Read More / View Supplemental Materials
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Oncotator: Cancer Variant Annotation Tool.Ramos, AH, Lichtenstein L., Gupta M., Lawrence MS, Pugh TJ, Saksena G., Meyerson M., and Getz G. Human mutation, 2015/02/23, (2015) Read More / View Supplemental Materials
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A Genome-Wide siRNA Screen in Mammalian Cells for Regulators of S6 Phosphorylation.Papageorgiou, A., Rapley J., Mesirov J. P., Tamayo P., and Avruch J. PloS one, 2015/01/01, Volume 10, Issue 3, p.e0116096, (2015) Read More / View Supplemental Materials
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Genetic modifiers of EGFR dependence in non-small cell lung cancer.Sharifnia, T., Rusu V., Piccioni F., Bagul M., Imielinski M., Cherniack AD, Pedamallu CS, Wong B., Wilson FH, Garraway LA, Altshuler D., Golub T. R., Root DE, Subramanian A., and Meyerson M. Proceedings of the National Academy of Sciences of the United States of America, 2014/12/15, (2014) Read More / View Supplemental Materials
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Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.Perry, JA, Kiezun A., Tonzi P., Van Allen EM, Carter SL, Baca SC, Cowley GS, Bhatt AS, Rheinbay E., Pedamallu CS, Helman E., Taylor-Weiner A., McKenna A., Deluca DS, Lawrence MS, Ambrogio L., Sougnez C., Sivachenko A., Walensky LD, Wagle N., et al. Proceedings of the National Academy of Sciences of the United States of America, 2014/12/15, (2014) Read More / View Supplemental Materials
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Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1).Fang, C., D'Souza B., Thompson CF, Clifton MC, Fairman JW, Fulroth B., Leed A., McCarren P., Wang L., Wang Y., Feau C., Kaushik VK, Palmer M., Wei G., Golub T. R., Hubbard BK, and Serrano-Wu MH ACS medicinal chemistry letters, 2014/12/11, Volume 5, Issue 12, p.1308-12, (2014) Read More / View Supplemental Materials
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Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes.Jaiswal, S., Fontanillas P., Flannick J., Manning A., Grauman PV, Mar BG, Lindsley RC, Mermel CH, Burtt N., Chavez A., Higgins JM, Moltchanov V., Kuo FC, Kluk MJ, Henderson B., Kinnunen L., Koistinen HA, Ladenvall C., Getz G., Correa A., et al. The New England journal of medicine, 2014/11/26, (2014) Read More / View Supplemental Materials
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TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients. Blood, 2014/09/15, (2014) Read More / View Supplemental Materials
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The Genomic Landscape of Pediatric Ewing Sarcoma.Crompton, BD, Stewart C., Taylor-Weiner A., Alexe G., Kurek KC, Calicchio ML, Kiezun A., Carter SL, Shukla SA, Mehta SS, Thorner AR, de Torres C., Lavarino C., Sunol M., McKenna A., Sivachenko A., Cibulskis K., Lawrence MS, Stojanov P., Rosenberg M., et al. Cancer discovery, 2014/09/03, (2014) Read More / View Supplemental Materials
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Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine.Van Allen, EM, Wagle N., Stojanov P., Perrin DL, Cibulskis K., Marlow S., Jane-Valbuena J., Friedrich DC, Kryukov G., Carter SL, McKenna A., Sivachenko A., Rosenberg M., Kiezun A., Voet D., Lawrence M., Lichtenstein LT, Gentry JG, Huang FW, Fostel J., et al. Nature medicine, 2014/06/01, Volume 20, Issue 6, p.682-8, (2014) Read More / View Supplemental Materials
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Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing.Helman, E., Lawrence ML, Stewart C., Sougnez C., Getz G., and Meyerson M. Genome research, 2014/05/13, (2014) Read More / View Supplemental Materials
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Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer.Lohr, JG, Adalsteinsson VA, Cibulskis K., Choudhury AD, Rosenberg M., Cruz-Gordillo P., Francis JM, Zhang CZ, Shalek AK, Satija R., Trombetta JJ, Lu D., Tallapragada N., Tahirova N., Kim S., Blumenstiel B., Sougnez C., Lowe A., Wong B., Auclair D., et al. Nature biotechnology, 2014/05/01, Volume 32, Issue 5, p.479-84, (2014) Read More / View Supplemental Materials
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Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL.Wang, L., Shalek AK, Lawrence M., Ding R., Gaublomme JT, Pochet N., Stojanov P., Sougnez C., Shukla SA, Stevenson KE, Zhang W., Wong J., Sievers QL, Macdonald BT, Vartanov AR, Goldstein NR, Neuberg D., He X., Lander E., Hacohen N., et al. Blood, 2014/04/28, (2014) Read More / View Supplemental Materials
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