Recent Cancer Papers

Paired exome analysis of Barrett's esophagus and adenocarcinoma.Stachler, MD, Taylor-Weiner A., Peng S., McKenna A., Loda M., Stewart C., Stojanov P., Seepo S., Lawrence MS, Lin J., Chang AC, Gabriel SB, Lander E. S., Beer DG, Getz G., Carter SL, and Bass AJ Nature genetics, 2015/07/20, (2015) Read More / View Supplemental Materials
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Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.Krönke, J., Fink EC, Hollenbach PW, MacBeth KJ, Hurst SN, Udeshi ND, Chamberlain PP, Mani D. R., Man HW, Gandhi AK, Svinkina T., Schneider RK, McConkey M., Järås M., Griffiths E., Wetzler M., Bullinger L., Cathers BE, Carr SA, Chopra R., et al. Nature, 2015/07/09, Volume 523, Issue 7559, p.183-8, (2015) Read More / View Supplemental Materials
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An ecosystem of cancer cell line factories to support a cancer dependency map.Boehm, JS, and Golub T. R. Nature reviews. Genetics, 2015/07/01, Volume 16, Issue 7, p.373-4, (2015) Read More / View Supplemental Materials
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Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.Cancer Genome Atlas Research, Network, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E., Miller CR, Vitucci M., Morozova O., Robertson AG, Noushmehr H., Laird PW, Cherniack AD, Akbani R., Huse JT, Ciriello G., Poisson LM, Barnholtz-Sloan JS, et al. The New England journal of medicine, 2015/06/25, Volume 372, Issue 26, p.2481-98, (2015) Read More / View Supplemental Materials
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Chromothripsis from DNA damage in micronuclei.Zhang, CZ, Spektor A., Cornils H., Francis JM, Jackson EK, Liu S., Meyerson M., and Pellman D. Nature, 2015/05/27, (2015) Read More / View Supplemental Materials
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Precision medicine in breast cancer: genes, genomes, and the future of genomically driven treatments.Stover, DG, and Wagle N. Current oncology reports, 2015/04/01, Volume 17, Issue 4, p.15, (2015) Read More / View Supplemental Materials
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Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations.Ahronian, LG, Sennott EM, Van Allen EM, Wagle N., Kwak EL, Faris JE, Godfrey JT, Nishimura K., Lynch KD, Mermel CH, Lockerman EL, Kalsy A., Gurski JM Jr, Bahl S., Anderka K., Green LM, Lennon NJ, Huynh TG, Mino-Kenudson M., Getz G., et al. Cancer discovery, 2015/04/01, Volume 5, Issue 4, p.358-67, (2015) Read More / View Supplemental Materials
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Dynamic epigenetic regulation by menin during pancreatic islet tumor formation.Lin, W., Watanabe H., Peng S., Francis JM, Kaplan N., Pedamallu CS, Ramachandran A., Agoston A., Bass AJ, and Meyerson M. Molecular cancer research : MCR, 2015/04/01, Volume 13, Issue 4, p.689-98, (2015) Read More / View Supplemental Materials
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The tumor virus landscape of AIDS-related lymphomas.Arvey, A., Ojesina A., Pedamallu CS, Ballon G., Jung J., Duke F., Leoncini L., De Falco G., Bressman E., Tam W., Chadburn A., Meyerson M., and Cesarman E. Blood, 2015/03/31, (2015) Read More / View Supplemental Materials
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DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.Chen, CW, Koche RP, Sinha AU, Deshpande AJ, Zhu N., Eng R., Doench JG, Xu H., Chu SH, Qi J., Wang X., Delaney C., Bernt KM, Root DE, Hahn WC, Bradner JE, and Armstrong SA Nature medicine, 2015/03/30, (2015) Read More / View Supplemental Materials
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PLZF, a Tumor Suppressor Genetically Lost in Metastatic Castration Resistant Prostate Cancer, is a Mediator of Resistance to Androgen Deprivation Therapy.Hsieh, CL, Botta G., Gao S., Li T., Van Allen EM, Treacy DJ, Cai C., He HH, Sweeney CJ, Brown M., Balk SP, Nelson PS, Garraway LA, and Kantoff PW Cancer research, 2015/03/25, (2015) Read More / View Supplemental Materials
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Inactivation of HDAC1 or HDAC2 induces gamma globin expression without altering cell cycle or proliferation.Esrick, EB, McConkey M., Lin K., Frisbee A., and Ebert BL American journal of hematology, 2015/03/23, (2015) Read More / View Supplemental Materials
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A genomic data viewer for iPad.Thorvaldsdóttir, H., Robinson JT, Turner D., and Mesirov J. P. Genome biology, 2015/02/26, Volume 16, p.46, (2015) Read More / View Supplemental Materials
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Oncotator: Cancer Variant Annotation Tool.Ramos, AH, Lichtenstein L., Gupta M., Lawrence MS, Pugh TJ, Saksena G., Meyerson M., and Getz G. Human mutation, 2015/02/23, (2015) Read More / View Supplemental Materials
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Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects.Singh, S., Wu X., Ljosa V., Bray MA, Piccioni F., Root DE, Doench JG, Boehm JS, and Carpenter AE PloS one, 2015/01/01, Volume 10, Issue 7, p.e0131370, (2015) Read More / View Supplemental Materials
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A Genome-Wide siRNA Screen in Mammalian Cells for Regulators of S6 Phosphorylation.Papageorgiou, A., Rapley J., Mesirov J. P., Tamayo P., and Avruch J. PloS one, 2015/01/01, Volume 10, Issue 3, p.e0116096, (2015) Read More / View Supplemental Materials
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Next-generation sequencing to guide cancer therapy.Gagan, J., and Van Allen EM Genome medicine, 2015/01/01, Volume 7, Issue 1, p.80, (2015) Read More / View Supplemental Materials
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Genetic modifiers of EGFR dependence in non-small cell lung cancer.Sharifnia, T., Rusu V., Piccioni F., Bagul M., Imielinski M., Cherniack AD, Pedamallu CS, Wong B., Wilson FH, Garraway LA, Altshuler D., Golub T. R., Root DE, Subramanian A., and Meyerson M. Proceedings of the National Academy of Sciences of the United States of America, 2014/12/15, (2014) Read More / View Supplemental Materials
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Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.Perry, JA, Kiezun A., Tonzi P., Van Allen EM, Carter SL, Baca SC, Cowley GS, Bhatt AS, Rheinbay E., Pedamallu CS, Helman E., Taylor-Weiner A., McKenna A., Deluca DS, Lawrence MS, Ambrogio L., Sougnez C., Sivachenko A., Walensky LD, Wagle N., et al. Proceedings of the National Academy of Sciences of the United States of America, 2014/12/15, (2014) Read More / View Supplemental Materials
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