Recent Cancer Papers

A genomic data viewer for iPad.Thorvaldsdóttir, H., Robinson JT, Turner D., and Mesirov J. P. Genome biology, 2015/02/26, Volume 16, p.46, (2015) Read More / View Supplemental Materials
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Oncotator: Cancer Variant Annotation Tool.Ramos, AH, Lichtenstein L., Gupta M., Lawrence MS, Pugh TJ, Saksena G., Meyerson M., and Getz G. Human mutation, 2015/02/23, (2015) Read More / View Supplemental Materials
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Genetic modifiers of EGFR dependence in non-small cell lung cancer.Sharifnia, T., Rusu V., Piccioni F., Bagul M., Imielinski M., Cherniack AD, Pedamallu CS, Wong B., Wilson FH, Garraway LA, Altshuler D., Golub T. R., Root DE, Subramanian A., and Meyerson M. Proceedings of the National Academy of Sciences of the United States of America, 2014/12/15, (2014) Read More / View Supplemental Materials
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Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.Perry, JA, Kiezun A., Tonzi P., Van Allen EM, Carter SL, Baca SC, Cowley GS, Bhatt AS, Rheinbay E., Pedamallu CS, Helman E., Taylor-Weiner A., McKenna A., Deluca DS, Lawrence MS, Ambrogio L., Sougnez C., Sivachenko A., Walensky LD, Wagle N., et al. Proceedings of the National Academy of Sciences of the United States of America, 2014/12/15, (2014) Read More / View Supplemental Materials
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Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1).Fang, C., D'Souza B., Thompson CF, Clifton MC, Fairman JW, Fulroth B., Leed A., McCarren P., Wang L., Wang Y., Feau C., Kaushik VK, Palmer M., Wei G., Golub T. R., Hubbard BK, and Serrano-Wu MH ACS medicinal chemistry letters, 2014/12/11, Volume 5, Issue 12, p.1308-12, (2014) Read More / View Supplemental Materials
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Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes.Jaiswal, S., Fontanillas P., Flannick J., Manning A., Grauman PV, Mar BG, Lindsley RC, Mermel CH, Burtt N., Chavez A., Higgins JM, Moltchanov V., Kuo FC, Kluk MJ, Henderson B., Kinnunen L., Koistinen HA, Ladenvall C., Getz G., Correa A., et al. The New England journal of medicine, 2014/11/26, (2014) Read More / View Supplemental Materials
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TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients. Blood, 2014/09/15, (2014) Read More / View Supplemental Materials
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The Genomic Landscape of Pediatric Ewing Sarcoma.Crompton, BD, Stewart C., Taylor-Weiner A., Alexe G., Kurek KC, Calicchio ML, Kiezun A., Carter SL, Shukla SA, Mehta SS, Thorner AR, de Torres C., Lavarino C., Sunol M., McKenna A., Sivachenko A., Cibulskis K., Lawrence MS, Stojanov P., Rosenberg M., et al. Cancer discovery, 2014/09/03, (2014) Read More / View Supplemental Materials
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Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine.Van Allen, EM, Wagle N., Stojanov P., Perrin DL, Cibulskis K., Marlow S., Jane-Valbuena J., Friedrich DC, Kryukov G., Carter SL, McKenna A., Sivachenko A., Rosenberg M., Kiezun A., Voet D., Lawrence M., Lichtenstein LT, Gentry JG, Huang FW, Fostel J., et al. Nature medicine, 2014/06/01, Volume 20, Issue 6, p.682-8, (2014) Read More / View Supplemental Materials
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Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing.Helman, E., Lawrence ML, Stewart C., Sougnez C., Getz G., and Meyerson M. Genome research, 2014/05/13, (2014) Read More / View Supplemental Materials
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Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer.Lohr, JG, Adalsteinsson VA, Cibulskis K., Choudhury AD, Rosenberg M., Cruz-Gordillo P., Francis JM, Zhang CZ, Shalek AK, Satija R., Trombetta JJ, Lu D., Tallapragada N., Tahirova N., Kim S., Blumenstiel B., Sougnez C., Lowe A., Wong B., Auclair D., et al. Nature biotechnology, 2014/05/01, Volume 32, Issue 5, p.479-84, (2014) Read More / View Supplemental Materials
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Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL.Wang, L., Shalek AK, Lawrence M., Ding R., Gaublomme JT, Pochet N., Stojanov P., Sougnez C., Shukla SA, Stevenson KE, Zhang W., Wong J., Sievers QL, Macdonald BT, Vartanov AR, Goldstein NR, Neuberg D., He X., Lander E., Hacohen N., et al. Blood, 2014/04/28, (2014) Read More / View Supplemental Materials
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A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors.Konieczkowski, DJ, Johannessen CM, Abudayyeh O., Kim JW, Cooper ZA, Piris A., Frederick DT, Barzily-Rokni M., Straussman R., Haq R., Fisher DE, Mesirov J. P., Hahn WC, Flaherty KT, Wargo JA, Tamayo P., and Garraway LA Cancer discovery, 2014/04/25, (2014) Read More / View Supplemental Materials
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Targeted genomic rearrangements using CRISPR/Cas technology.Choi, PS, and Meyerson M. Nature communications, 2014/04/24, Volume 5, p.3728, (2014) Read More / View Supplemental Materials
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A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein.Pop, MS, Stransky N., Garvie CW, Theurillat JP, Lewis TA, Zhong C., Culyba EK, Lin F., Daniels DS, Pagliarini R., Ronco L., Koehler AN, and Garraway LA Molecular cancer therapeutics, 2014/04/15, (2014) Read More / View Supplemental Materials
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SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas.Watanabe, H., Ma Q., Peng S., Adelmant G., Swain D., Song W., Fox C., Francis JM, Pedamallu CS, Deluca DS, Brooks AN, Wang S., Que J., Rustgi AK, Wong KK, Ligon KL, Liu XS, Marto JA, Meyerson M., and Bass AJ The Journal of clinical investigation, 2014/04/01, Volume 124, Issue 4, p.1636-45, (2014) Read More / View Supplemental Materials
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Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib.Wagle, N., Grabiner BC, Van Allen EM, Hodis E., Jacobus S., Supko JG, Stewart M., Choueiri TK, Gandhi L., Cleary JM, Elfiky AA, Taplin ME, Stack EC, Signoretti S., Loda M., Shapiro GI, Sabatini DM, Lander E. S., Gabriel SB, Kantoff PW, et al. Cancer discovery, 2014/03/27, (2014) Read More / View Supplemental Materials
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Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing.McFadden, DG, Papagiannakopoulos T., Taylor-Weiner A., Stewart C., Carter SL, Cibulskis K., Bhutkar A., McKenna A., Dooley A., Vernon A., Sougnez C., Malstrom S., Heimann M., Park J., Chen F., Farago AF, Dayton T., Shefler E., Gabriel S., Getz G., et al. Cell, 2014/03/13, Volume 156, Issue 6, p.1298-311, (2014) Read More / View Supplemental Materials
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ARID1B is a specific vulnerability in ARID1A-mutant cancers.Helming, KC, Wang X., Wilson BG, Vazquez F., Haswell JR, Manchester HE, Kim Y., Kryukov GV, Ghandi M., Aguirre AJ, Jagani Z., Wang Z., Garraway LA, Hahn WC, and Roberts CW Nature medicine, 2014/03/01, Volume 20, Issue 3, p.251-4, (2014) Read More / View Supplemental Materials
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Residual Complexes Containing SMARCA2 (BRM) Underlie the Oncogenic Drive of SMARCA4 (BRG1) Mutation.Wilson, BG, Helming KC, Wang X., Kim Y., Vazquez F., Jagani Z., Hahn WC, and Roberts CW Molecular and cellular biology, 2014/03/01, Volume 34, Issue 6, p.1136-44, (2014) Read More / View Supplemental Materials
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