Scientific Publications

Comparative gene marker selection suite

Publication TypeJournal Article
AuthorsGould, Joshua, Getz Gad, Monti Stefano, Reich Michael, and Mesirov Jill P.
AbstractMOTIVATION: An important step in analyzing expression profiles from microarray data is to identify genes that can discriminate between distinct classes of samples. Many statistical approaches for assigning significance values to genes have been developed. The Comparative Marker Selection suite consists of three modules that allow users to apply and compare different methods of computing significance for each marker gene, a viewer to assess the results, and a tool to create derivative datasets and marker lists based on user-defined significance criteria. AVAILABILITY: The Comparative Marker Selection application suite is freely available as a GenePattern module. The GenePattern analysis environment is freely available at http://www.broad.mit.edu/genepattern.
Year of Publication2006
JournalBioinformatics (Oxford, England)
Volume22
Issue15
Pages1924 - 5
Date Published (YYYY/MM/DD)2006/08/01/
ISBN Number1460-2059
KeywordsAlgorithms, Cancer, Computer Simulation, Gene Expression Profiling, Genetic, Genetic Markers, Information Storage and Retrieval, Models, Oligonucleotide Array Sequence Analysis, Statistical, User-Computer Interface