Pharmacogenomic agreement between two cancer cell line data sets.

Nature
Authors
Keywords
Abstract

Large cancer cell line collections broadly capture the genomic diversity of human cancers and provide valuable insight into anti-cancer drug response. Here we show substantial agreement and biological consilience between drug sensitivity measurements and their associated genomic predictors from two publicly available large-scale pharmacogenomics resources: The Cancer Cell Line Encyclopedia and the Genomics of Drug Sensitivity in Cancer databases.

Year of Publication
2015
Journal
Nature
Volume
528
Issue
7580
Pages
84-7
Date Published
2015 Dec 03
ISSN
1476-4687
URL
DOI
10.1038/nature15736
PubMed ID
26570998
Links
Grant list
086357 / Wellcome Trust / United Kingdom
102696 / Wellcome Trust / United Kingdom
1U54HG006097-01 / HG / NHGRI NIH HHS / United States
A16629 / Cancer Research UK / United Kingdom