Constellation Map: Downstream visualization and interpretation of gene set enrichment results.
F1000Res
Authors | |
Abstract | UNLABELLED: Gene set enrichment analysis (GSEA) approaches are widely used to identify coordinately regulated genes associated with phenotypes of interest. Here, we present Constellation Map, a tool to visualize and interpret the results when enrichment analyses yield a long list of significantly enriched gene sets. Constellation Map identifies commonalities that explain the enrichment of multiple top-scoring gene sets and maps the relationships between them. Constellation Map can help investigators take full advantage of GSEA and facilitates the biological interpretation of enrichment results. AVAILABILITY: Constellation Map is freely available as a GenePattern module at http://www.genepattern.org. |
Year of Publication | 2015
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Journal | F1000Res
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Volume | 4
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Pages | 167
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Date Published | 2015
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URL | |
DOI | 10.12688/f1000research.6644.1
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PubMed ID | 26594333
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PubMed Central ID | PMC4648224
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Links | |
Grant list | R01 CA121941 / CA / NCI NIH HHS / United States
R01 GM074024 / GM / NIGMS NIH HHS / United States
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