From Dish to Bedside: Lessons Learned While Translating Findings from a Stem Cell Model of Disease to a Clinical Trial.

Cell Stem Cell
Authors
Keywords
Abstract

While iPSCs have created unprecedented opportunities for drug discovery, there remains uncertainty concerning the path to the clinic for candidate therapeutics discovered with their use. Here we share lessons that we learned, and believe are generalizable to similar efforts, while taking a discovery made using iPSCs into a clinical trial.

Year of Publication
2015
Journal
Cell Stem Cell
Volume
17
Issue
1
Pages
8-10
Date Published
2015 Jul 02
ISSN
1875-9777
URL
DOI
10.1016/j.stem.2015.06.013
PubMed ID
26140603
Links
Grant list
R01 NS038253 / NS / NINDS NIH HHS / United States
Howard Hughes Medical Institute / United States