Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.
Nat Commun
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| Abstract | Metabolites are small molecules involved in cellular metabolism, which can be detected in biological samples using metabolomic techniques. Here we present the results of genome-wide association and meta-analyses for variation in the blood serum levels of 129 metabolites as measured by the Biocrates metabolomic platform. In a discovery sample of 7,478 individuals of European descent, we find 4,068 genome- and metabolome-wide significant (Z-test, P |
| Year of Publication | 2015
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| Journal | Nat Commun
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| Volume | 6
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| Pages | 7208
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| Date Published | 2015 Jun 12
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| ISSN | 2041-1723
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| URL | |
| DOI | 10.1038/ncomms8208
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| PubMed ID | 26068415
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| PubMed Central ID | PMC4745136
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| Grant list | 230374 / European Research Council / International
R01 DK075787 / DK / NIDDK NIH HHS / United States
R01DK075787 / DK / NIDDK NIH HHS / United States
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