Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.

Nat Commun
Authors
Keywords
Abstract

Variation in body iron is associated with or causes diseases, including anaemia and iron overload. Here, we analyse genetic association data on biochemical markers of iron status from 11 European-population studies, with replication in eight additional cohorts (total up to 48,972 subjects). We find 11 genome-wide-significant (P

Year of Publication
2014
Journal
Nat Commun
Volume
5
Pages
4926
Date Published
2014 Oct 29
ISSN
2041-1723
URL
DOI
10.1038/ncomms5926
PubMed ID
25352340
PubMed Central ID
PMC4215164
Links
Grant list
RP-PG-0310-1002 / Department of Health / United Kingdom
R01 AA014041 / AA / NIAAA NIH HHS / United States
MC_UU_12015/1 / Medical Research Council / United Kingdom
MC_U106179471 / Medical Research Council / United Kingdom
U54 EB020403 / EB / NIBIB NIH HHS / United States
RG/09/012/28096 / British Heart Foundation / United Kingdom