Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.
Nat Commun
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Abstract | Variation in body iron is associated with or causes diseases, including anaemia and iron overload. Here, we analyse genetic association data on biochemical markers of iron status from 11 European-population studies, with replication in eight additional cohorts (total up to 48,972 subjects). We find 11 genome-wide-significant (P |
Year of Publication | 2014
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Journal | Nat Commun
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Volume | 5
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Pages | 4926
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Date Published | 2014 Oct 29
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ISSN | 2041-1723
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URL | |
DOI | 10.1038/ncomms5926
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PubMed ID | 25352340
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PubMed Central ID | PMC4215164
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Grant list | RP-PG-0310-1002 / Department of Health / United Kingdom
R01 AA014041 / AA / NIAAA NIH HHS / United States
MC_UU_12015/1 / Medical Research Council / United Kingdom
MC_U106179471 / Medical Research Council / United Kingdom
U54 EB020403 / EB / NIBIB NIH HHS / United States
RG/09/012/28096 / British Heart Foundation / United Kingdom
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