Scientific Publications

Twelve-Single Nucleotide Polymorphism Genetic Risk Score Identifies Individuals at Increased Risk for Future Atrial Fibrillation and Stroke.

Publication TypeJournal Article
AuthorsTada, H., Shiffman D., Smith JG, Sjögren M., Lubitz SA, Ellinor PT, Louie JZ, Catanese JJ, Engström G., Devlin JJ, Kathiresan S., and Melander O.
AbstractAtrial fibrillation (AF) is prevalent and there is a clinical need for biomarkers to identify individuals at higher risk for AF. Fixed throughout a life course and assayable early in life, genetic biomarkers may meet this need. Here, we investigate whether multiple single nucleotide polymorphisms together as an AF genetic risk score (AF-GRS) can improve prediction of one's risk for AF.
Year of Publication2014
JournalStroke; a journal of cerebral circulation
Date Published (YYYY/MM/DD)2014/08/14
ISSN Number0039-2499
DOI10.1161/STROKEAHA.114.006072
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/25123217?dopt=Abstract