Scientific Publications

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance.

Publication TypeJournal Article
AuthorsRamos, YF, Metrustry S., Arden N., Bay-Jensen AC, Beekman M., de Craen AJ, Cupples LA, Esko T., Evangelou E., Felson DT, Hart DJ, Ioannidis JP, Karsdal M., Kloppenburg M., Lafeber F., Metspalu A., Panoutsopoulou K., Slagboom PE, Spector TD, van Spil EW, Uitterlinden AG, Zhu Y., arcOGENconsortium, collaborators TreatOA, Valdes AM, van Meurs JB, and Meulenbelt I.
AbstractResearch for the use of biomarkers in osteoarthritis (OA) is promising, however, adequate discrimination between patients and controls may be hampered due to innate differences. We set out to identify loci influencing levels of serum cartilage oligomeric protein (sCOMP) and urinary C-telopeptide of type II collagen (uCTX-II).
Year of Publication2014
JournalJournal of medical genetics
Date Published (YYYY/MM/DD)2014/07/23
ISSN Number0022-2593
DOI10.1136/jmedgenet-2014-102478
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/25057126?dopt=Abstract