Scientific Publications

SPSB1 May Have MET Its Match during Breast Cancer Recurrence.

Publication TypeJournal Article
AuthorsQin, Y., and McAllister SS
AbstractDisease recurrence is the most common cause of death for patients with breast cancer, yet little is known about the molecular mechanisms underlying this process. Using inducible transgenic mouse model systems, Feng and colleagues identified SPSB1 as a determinant of breast cancer recurrence by virtue of its ability to protect tumor cells from apoptosis through c-MET activation. Cancer Discov; 4(7); 760-1. ©2014 AACR. See related article by Feng et al., p. 790.
Year of Publication2014
JournalCancer discovery
Volume4
Issue7
Pages760-1
Date Published (YYYY/MM/DD)2014/07/01
ISSN Number2159-8274
DOI10.1158/2159-8290.CD-14-0505
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/25002612?dopt=Abstract