Scientific Publications

Effect of Genetic Variants Associated With Plasma Homocysteine Levels on Stroke Risk.

Publication TypeJournal Article
AuthorsCotlarciuc, I., Malik R., Holliday EG, Ahmadi KR, Paré G., Psaty BM, Fornage M., Hasan N., Rinne PE, Ikram MA, Markus HS, Rosand J., Mitchell BD, Kittner SJ, Meschia JF, van Meurs JB, Uitterlinden AG, Worrall BB, Dichgans M., Sharma P., and on behalf of METASTROKE and the International Stroke Genetics Consortium
AbstractElevated total plasma homocysteine (tHcy) levels are known to be associated with increased risk of ischemic stroke (IS). Given that both tHcy and IS are heritable traits, we investigated a potential genetic relationship between homocysteine levels and stroke risk by assessing 18 polymorphisms previously associated with tHcy levels for their association with IS and its subtypes.
Year of Publication2014
JournalStroke; a journal of cerebral circulation
Date Published (YYYY/MM/DD)2014/05/20
ISSN Number0039-2499
DOI10.1161/STROKEAHA.114.005208
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/24846872?dopt=Abstract