Scientific Publications

'Lnc'-ing enhancers to MYC regulation.

Publication TypeJournal Article
AuthorsYounger, ST, and Rinn JL
AbstractLong noncoding RNAs (lncRNAs) are emerging as important functional components in the establishment of long-range chromosomal interactions. In a recent paper published in Cell Research, Xiang et al. provide mechanistic insight into this phenomenon by characterizing the role of CCAT1-L, a colorectal cancer-specific lncRNA, in intra-chromosome looping between the MYC gene promoter and distal upstream enhancer elements that regulate MYC transcription.
Year of Publication2014
JournalCell research
Date Published (YYYY/MM/DD)2014/04/29
ISSN Number1001-0602
DOI10.1038/cr.2014.54
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/24777251?dopt=Abstract