Scientific Publications

Pathway analyses implicate glial cells in schizophrenia.

Publication TypeJournal Article
AuthorsDuncan, LE, Holmans PA, Lee PH, O'Dushlaine CT, Kirby AW, Smoller JW, Öngür D., and Cohen BM
AbstractThe quest to understand the neurobiology of schizophrenia and bipolar disorder is ongoing with multiple lines of evidence indicating abnormalities of glia, mitochondria, and glutamate in both disorders. Despite high heritability estimates of 81% for schizophrenia and 75% for bipolar disorder, compelling links between findings from neurobiological studies, and findings from large-scale genetic analyses, are only beginning to emerge.
Year of Publication2014
JournalPloS one
Volume9
Issue2
Pagese89441
Date Published (YYYY/MM/DD)2014/01/01
DOI10.1371/journal.pone.0089441
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/24586781?dopt=Abstract