Scientific Publications

Rare Copy Number Variation in Treatment-Resistant Major Depressive Disorder.

Publication TypeJournal Article
AuthorsO'Dushlaine, C., Ripke S., Ruderfer DM, Hamilton SP, Fava M., Iosifescu DV, Kohane IS, Churchill SE, Castro VM, Clements CC, Blumenthal SR, Murphy SN, Smoller JW, and Perlis RH
AbstractWhile antidepressant treatment response appears to be partially heritable, no consistent genetic associations have been identified. Large, rare copy number variants (CNVs) play a role in other neuropsychiatric diseases, so we assessed their association with treatment-resistant depression (TRD).
Year of Publication2014
JournalBiological psychiatry
Date Published (YYYY/MM/DD)2014/01/19
ISSN Number0006-3223
DOI10.1016/j.biopsych.2013.10.028
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/24529801?dopt=Abstract