Scientific Publications

SMAD3 gene variant is a risk factor for recurrent surgery in patients with Crohn's disease.

Publication TypeJournal Article
AuthorsFowler, SA, Ananthakrishnan AN, Gardet A., Stevens CR, Korzenik JR, Sands BE, Daly M. J., Xavier RJ, and Yajnik V.
AbstractMore than 80% of Crohn's disease (CD) patients will require surgery. Surgery is not curative and rates of re-operation are high. Identification of genetic variants associated with repeat surgery would allow risk stratification of patients who may benefit from early aggressive therapy and/or post-operative prophylactic treatment.
Year of Publication2014
JournalJournal of Crohn's & colitis
Date Published (YYYY/MM/DD)2014/01/22
ISSN Number1873-9946
DOI10.1016/j.crohns.2014.01.003
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/24461721?dopt=Abstract