Scientific Publications

RhoGTPases - NODes for effector-triggered immunity in animals.

Publication TypeJournal Article
AuthorsStuart, LM, and Boyer L.
AbstractA recent study published in Nature by Keestra and colleagues addresses how the immune system detects the pathogenic potential of microbes and provides evidence that one strategy involves NOD1, which monitors the activation state of the RhoGTPases that are targeted by virulence effectors produced by pathogenic microbes. Interestingly, their findings reveal striking similarities with previous observations made in flies and plants, establishing the evolutionary conservation of this detection system in the innate immune arsenal in many taxa.
Year of Publication2013
JournalCell research
Date Published (YYYY/MM/DD)2013/05/21
ISSN Number1001-0602
DOI10.1038/cr.2013.68
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/23689278?dopt=Abstract