An inflammatory situation: SOX2 and STAT3 cooperate in squamous cell carcinoma initiation.
Cell Stem Cell
Authors | |
Abstract | Although SOX2 has been identified as a squamous cell carcinoma oncogene, mechanisms of SOX2-induce oncogenesis have remained elusive. In this issue of Cell Stem Cell, Li et al. (2013) show that SOX2 synergizes with inflammation-induced STAT3 activation to transform basal progenitors and initiate squamous cell carcinoma. |
Year of Publication | 2013
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Journal | Cell Stem Cell
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Volume | 12
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Issue | 3
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Pages | 266-8
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Date Published | 2013 Mar 07
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ISSN | 1875-9777
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URL | |
DOI | 10.1016/j.stem.2013.02.004
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PubMed ID | 23472866
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